Experiment set12IT033 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_glucose with 2,2'-Dipyridyl 200 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS23920 -7.6 -5.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS26085 -5.4 -3.7 3-dehydroquinate synthase compare
BWI76_RS00400 -5.0 -3.4 glutamine synthetase compare
BWI76_RS04465 -4.7 -7.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04470 -4.7 -10.8 carbamoyl phosphate synthase large subunit compare
BWI76_RS02995 -4.4 -12.0 aspartate carbamoyltransferase compare
BWI76_RS23360 -4.4 -4.9 diaminopimelate decarboxylase compare
BWI76_RS27385 -4.4 -9.9 orotate phosphoribosyltransferase compare
BWI76_RS09755 -4.3 -10.4 phosphoserine transaminase compare
BWI76_RS21265 -4.3 -14.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS10990 -4.3 -5.1 dihydroorotase compare
BWI76_RS17720 -4.3 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS21475 -4.1 -6.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS07065 -4.1 -9.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS05835 -4.1 -5.2 gamma-glutamyl-phosphate reductase compare
BWI76_RS01615 -4.0 -10.3 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS01610 -3.9 -6.2 phosphoribosylamine--glycine ligase compare
BWI76_RS04160 -3.9 -4.9 phosphoserine phosphatase compare
BWI76_RS20965 -3.8 -5.2 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS04645 -3.7 -7.3 3-dehydroquinase compare
BWI76_RS00850 -3.7 -8.7 acetylglutamate kinase compare
BWI76_RS02530 -3.7 -3.5 tRNA dimethylallyltransferase compare
BWI76_RS20895 -3.6 -7.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS05840 -3.6 -8.2 glutamate 5-kinase compare
BWI76_RS09910 -3.6 -14.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS20350 -3.5 -9.3 amidophosphoribosyltransferase compare
BWI76_RS23365 -3.4 -6.4 LysR family transcriptional regulator compare
BWI76_RS07070 -3.4 -3.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00855 -3.3 -10.2 argininosuccinate lyase compare
BWI76_RS03010 -3.3 -9.3 ornithine carbamoyltransferase compare
BWI76_RS22755 -3.1 -7.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04255 -3.1 -11.1 threonine synthase compare
BWI76_RS04250 -3.1 -5.3 homoserine kinase compare
BWI76_RS23240 -3.1 -4.6 exonuclease V subunit gamma compare
BWI76_RS22765 -3.1 -13.2 sulfite reductase subunit alpha compare
BWI76_RS18930 -3.0 -7.3 histidinol-phosphate transaminase compare
BWI76_RS23220 -3.0 -9.8 amino-acid N-acetyltransferase compare
BWI76_RS18955 -3.0 -7.9 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS18950 -3.0 -7.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00845 -3.0 -7.8 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS01800 -3.0 -4.5 glucose-6-phosphate isomerase compare
BWI76_RS20355 -2.9 -6.7 colicin V production protein compare
BWI76_RS00975 -2.9 -8.7 dihydroxy-acid dehydratase compare
BWI76_RS09660 -2.9 -2.0 DNA translocase FtsK compare
BWI76_RS05015 -2.9 -4.7 transcriptional regulator compare
BWI76_RS09760 -2.8 -3.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS05200 -2.8 -3.6 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS23265 -2.8 -4.9 hypothetical protein compare
BWI76_RS00990 -2.8 -11.2 ketol-acid reductoisomerase compare
BWI76_RS18940 -2.8 -5.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS22760 -2.8 -6.5 sulfite reductase subunit beta compare
BWI76_RS23230 -2.8 -4.2 exodeoxyribonuclease V subunit beta compare
BWI76_RS27390 -2.7 -4.8 ribonuclease PH compare
BWI76_RS25115 -2.7 -9.5 argininosuccinate synthase compare
BWI76_RS22690 -2.6 -4.4 adenylyl-sulfate kinase compare
BWI76_RS00965 -2.6 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS04245 -2.5 -13.4 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS20650 -2.5 -3.7 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS17975 -2.4 -5.3 tail-specific protease compare
BWI76_RS00805 -2.4 -6.1 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS08385 -2.4 -2.9 citrate (Si)-synthase compare
BWI76_RS04685 -2.3 -10.1 putative leucine operon leader peptide compare
BWI76_RS25645 -2.3 -8.1 shikimate dehydrogenase compare
BWI76_RS11965 -2.3 -4.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS18925 -2.3 -5.0 histidinol dehydrogenase compare
BWI76_RS00785 -2.3 -7.1 cystathionine gamma-synthase compare
BWI76_RS22805 -2.3 -7.2 GTP diphosphokinase compare
BWI76_RS00980 -2.3 -13.2 PLP-dependent threonine dehydratase compare
BWI76_RS02735 -2.3 -6.8 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS18935 -2.2 -8.9 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS04680 -2.1 -14.1 2-isopropylmalate synthase compare
BWI76_RS00835 -2.1 -12.0 phosphoenolpyruvate carboxylase compare
BWI76_RS04665 -2.1 -16.0 3-isopropylmalate dehydratase small subunit compare
BWI76_RS11840 -2.1 -3.4 tryptophan synthase subunit alpha compare
BWI76_RS01655 -2.1 -6.4 homoserine O-succinyltransferase compare
BWI76_RS24285 -2.1 -7.7 cystathionine beta-lyase compare
BWI76_RS08520 -2.0 -2.0 colicin transporter TolQ compare
BWI76_RS25335 -2.0 -4.6 stringent starvation protein A compare
BWI76_RS15825 -2.0 -1.5 hypothetical protein compare
BWI76_RS26390 -2.0 -5.7 cell division protein FtsX compare
BWI76_RS06905 -1.9 -9.1 Cu+ exporting ATPase compare
BWI76_RS04240 -1.9 -3.7 thr operon leader peptide compare
BWI76_RS12495 -1.8 -2.6 2-Cys peroxiredoxin compare
BWI76_RS20995 -1.8 -4.6 RNA degradosome polyphosphate kinase compare
BWI76_RS25425 -1.8 -2.9 arginine repressor compare
BWI76_RS04675 -1.7 -5.8 3-isopropylmalate dehydrogenase compare
BWI76_RS09645 -1.7 -1.5 thioredoxin-disulfide reductase compare
BWI76_RS18920 -1.7 -3.4 ATP phosphoribosyltransferase compare
BWI76_RS26460 -1.6 -6.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS25320 -1.6 -6.5 glutamate synthase compare
BWI76_RS04670 -1.6 -8.0 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04530 -1.6 -2.3 peptidylprolyl isomerase SurA compare
BWI76_RS26620 -1.6 -1.9 Fe-S biogenesis protein NfuA compare
BWI76_RS18065 -1.6 -2.6 DNA polymerase III subunit theta compare
BWI76_RS04715 -1.6 -2.1 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS26395 -1.6 -4.1 cell division protein FtsE compare
BWI76_RS09655 -1.5 -3.9 leucine-responsive regulatory protein compare
BWI76_RS20380 -1.5 -1.8 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS11860 -1.5 -8.2 anthranilate synthase component I compare
BWI76_RS11845 -1.5 -4.7 tryptophan synthase subunit beta compare
BWI76_RS04955 -1.4 -2.2 hypoxanthine phosphoribosyltransferase compare
BWI76_RS11850 -1.4 -7.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS20435 -1.4 -1.6 chorismate synthase compare
BWI76_RS26000 -1.4 -7.7 aspartate aminotransferase family protein compare
BWI76_RS19850 -1.4 -2.7 tRNA-Pro compare
BWI76_RS25315 -1.3 -8.5 glutamate synthase large subunit compare
BWI76_RS26570 -1.3 -3.7 anion permease compare
BWI76_RS21465 -1.3 -5.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS11855 -1.3 -6.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00355 -1.3 -1.7 DNA polymerase I compare
BWI76_RS00385 -1.3 -5.7 nitrogen assimilation regulatory protein compare
BWI76_RS01200 -1.3 -1.6 diaminopimelate epimerase compare
BWI76_RS08605 -1.2 -2.9 phosphoglyceromutase compare
BWI76_RS26055 -1.2 -6.6 siroheme synthase compare
BWI76_RS07730 -1.2 -1.8 iron-enterobactin transporter membrane protein compare
BWI76_RS24900 -1.2 -1.8 DeoR family transcriptional regulator compare
BWI76_RS12090 -1.1 -2.8 HNH endonuclease compare
BWI76_RS00345 -1.1 -3.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS00985 -1.1 -4.4 transcriptional regulator IlvY compare
BWI76_RS17980 -1.1 -2.8 RNA chaperone ProQ compare
BWI76_RS22700 -1.1 -5.4 sulfate adenylyltransferase subunit 2 compare
BWI76_RS04270 -1.1 -3.6 transaldolase compare
BWI76_RS09650 -1.1 -3.4 hypothetical protein compare
BWI76_RS04305 -1.1 -1.1 molecular chaperone DnaJ compare
BWI76_RS16515 -1.1 -2.3 LysR family transcriptional regulator compare
BWI76_RS21480 -1.0 -4.6 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS00390 -1.0 -3.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS20640 -1.0 -4.5 cysteine synthase A compare
BWI76_RS16965 -1.0 -2.1 murein lipoprotein compare
BWI76_RS19845 -1.0 -3.6 phosphatase compare
BWI76_RS00970 -1.0 -2.9 branched chain amino acid aminotransferase compare
BWI76_RS21075 -1.0 -1.6 membrane protein compare
BWI76_RS26455 -1.0 -3.4 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS00960 -0.9 -4.4 acetolactate synthase 2 catalytic subunit compare
BWI76_RS13980 -0.9 -1.5 hypothetical protein compare
BWI76_RS00640 -0.9 -2.2 L-rhamnose mutarotase compare
BWI76_RS17110 -0.9 -1.5 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS01870 -0.9 -3.8 diacylglycerol kinase compare
BWI76_RS07705 -0.9 -3.1 enterochelin esterase compare
BWI76_RS06765 -0.9 -2.1 transcriptional regulator compare
BWI76_RS27440 -0.9 -2.4 DNA helicase RecG compare
BWI76_RS20440 -0.9 -0.9 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS08330 -0.9 -1.5 hypothetical protein compare
BWI76_RS15360 -0.9 -2.3 hypothetical protein compare
BWI76_RS11635 -0.9 -1.6 ABC transporter compare
BWI76_RS21570 -0.9 -2.2 RnfH family protein compare
BWI76_RS01790 -0.8 -5.0 lysine-sensitive aspartokinase 3 compare
BWI76_RS08525 -0.8 -1.5 colicin transporter compare
BWI76_RS06535 -0.8 -1.9 endopeptidase La compare
BWI76_RS26470 -0.8 -3.7 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS02580 -0.8 -1.0 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS23480 -0.8 -4.9 EAL domain-containing protein compare
BWI76_RS20970 -0.8 -1.4 phosphoribosylglycinamide formyltransferase compare
BWI76_RS16955 -0.8 -1.0 hypothetical protein compare
BWI76_RS15835 -0.8 -1.2 hypothetical protein compare
BWI76_RS07740 -0.8 -1.6 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS15035 -0.8 -1.4 metal ABC transporter permease compare
BWI76_RS20900 -0.8 -1.3 outer membrane protein assembly factor BamC compare
BWI76_RS16470 -0.8 -1.4 transcriptional repressor NemR compare
BWI76_RS01385 -0.7 -1.5 potassium transporter compare
BWI76_RS17805 -0.7 -1.1 membrane protein compare
BWI76_RS27235 -0.7 -4.6 murein hydrolase activator EnvC compare
BWI76_RS19035 -0.7 -3.5 dTDP-rhamnosyl transferase compare
BWI76_RS01115 -0.7 -2.3 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS19840 -0.7 -1.1 hypothetical protein compare
BWI76_RS01125 -0.7 -3.0 4-alpha-L-fucosyltransferase compare
BWI76_RS26200 -0.7 -4.5 starch synthase compare
BWI76_RS22695 -0.7 -2.8 sulfate adenylyltransferase compare
BWI76_RS01350 -0.7 -0.9 NAD(P)H-flavin reductase compare
BWI76_RS12870 -0.7 -1.7 putative phytanoyl-CoA dioxygenase compare
BWI76_RS20150 -0.7 -1.4 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS27820 -0.7 -0.9 ilvB operon leader peptide IvbL compare
BWI76_RS10835 -0.7 -1.1 hypothetical protein compare
BWI76_RS13330 -0.7 -1.1 tellurite resistance methyltransferase TehB compare
BWI76_RS01070 -0.7 -2.7 thiol reductase thioredoxin compare
BWI76_RS11755 -0.7 -2.1 catalase HPII compare
BWI76_RS01795 -0.7 -1.6 hypothetical protein compare
BWI76_RS20750 -0.7 -1.0 carboxysome structural protein EutK compare
BWI76_RS01210 -0.7 -0.9 tyrosine recombinase XerC compare
BWI76_RS21375 -0.7 -1.3 autonomous glycyl radical cofactor GrcA compare
BWI76_RS15920 -0.7 -1.2 hypothetical protein compare
BWI76_RS22950 -0.7 -2.0 membrane protein compare
BWI76_RS09150 -0.6 -1.7 DNA-binding transcriptional repressor DeoR compare
BWI76_RS24620 -0.6 -1.6 PadR family transcriptional regulator compare
BWI76_RS23930 -0.6 -3.4 transcriptional regulator ArgP compare
BWI76_RS23170 -0.6 -2.5 aldehyde dehydrogenase EutE compare
BWI76_RS01685 -0.6 -3.9 methionine synthase compare
BWI76_RS03995 -0.6 -2.1 hypothetical protein compare
BWI76_RS16315 -0.6 -1.0 SirA-like protein compare
BWI76_RS19050 -0.6 -4.0 NAD(P)-dependent oxidoreductase compare
BWI76_RS25225 -0.6 -1.9 ABC transporter permease compare
BWI76_RS09450 -0.6 -1.4 30S ribosomal protein S6--L-glutamate ligase compare
BWI76_RS00760 -0.6 -2.5 cell division protein FtsN compare
BWI76_RS18235 -0.6 -1.7 trehalose-phosphatase compare
BWI76_RS13960 -0.6 -1.9 urea ABC transporter periplasmic protein compare
BWI76_RS14870 -0.6 -1.8 hypothetical protein compare
BWI76_RS18565 -0.6 -1.1 pemk protein compare
BWI76_RS25070 -0.6 -1.1 hypothetical protein compare
BWI76_RS14050 -0.6 -1.8 AP endonuclease, family 2 compare
BWI76_RS16075 -0.6 -0.9 oxidoreductase compare


Specific Phenotypes

For 1 genes in this experiment

For stress 2,2'-Dipyridyl in Klebsiella michiganensis M5al

For stress 2,2'-Dipyridyl across organisms