Experiment set12IT031 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

Varel_Bryant_medium_Glucose with Chenodeoxycholic acid 0.25 mg/ml

200 most important genes:

  gene name fitness t score description  
BT0892 -6.4 -3.2 dihydroorotate dehydrogenase (NCBI ptt file) compare
BT3757 -6.3 -8.7 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) compare
BT3918 -6.1 -4.1 pyridoxal phosphate biosynthetic protein pdxJ (NCBI ptt file) compare
BT1607 -6.0 -4.1 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) compare
BT1421 -6.0 -4.8 hypothetical protein (NCBI ptt file) compare
BT2074 -5.9 -9.1 ketol-acid reductoisomerase (NCBI ptt file) compare
BT2402 -5.9 -9.8 phosphoglycerate mutase (NCBI ptt file) compare
BT3933 -5.8 -6.9 prephenate dehydrogenase (EC 1.3.1.13) (from data) compare
BT3193 -5.8 -10.4 putative coenzyme A transferase (NCBI ptt file) compare
BT3761 -5.7 -5.6 N-succinylglutamate synthase (from data) compare
BT2401 -5.7 -7.9 threonine synthase (NCBI ptt file) compare
BT3395 -5.7 -12.2 N-succinylglutamate kinase (EC 2.7.2.-) (from data) compare
BT3733 -5.6 -12.6 arginosuccinate lyase (EC 4.3.2.1) (from data) compare
BT2837 -5.6 -15.7 2-oxoglutarate synthase subunit korB (NCBI ptt file) compare
BT3759 -5.6 -8.6 N-succinylglutamylphosphate reductase (EC 1.2.1.-) (from data) compare
BT2836 -5.5 -17.6 2-oxoglutarate synthase subunit korA (NCBI ptt file) compare
BT1746 -5.5 -2.8 conserved hypothetical protein (NCBI ptt file) compare
BT3758 -5.4 -3.7 N-succinylornithine aminotransferase (EC 2.6.1.81) (from data) compare
BT1843 -5.4 -7.4 adenylosuccinate synthetase (NCBI ptt file) compare
BT0891 -5.4 -3.7 dihydroorotate dehydrogenase electron transfer subunit (NCBI ptt file) compare
BT3253 -5.4 -3.7 phosphoribosylamine--glycine ligase (NCBI ptt file) compare
BT2078 -5.3 -8.2 dihydroxy-acid dehydratase (NCBI ptt file) compare
BT3549 -5.3 -3.6 N-succinylcitrulline desuccinylase (EC 3.5.1.-) (from data) compare
BT1857 -5.3 -8.8 3-isopropylmalate dehydrogenase (NCBI ptt file) compare
BT1859 -5.2 -3.6 3-isopropylmalate dehydratase small subunit (NCBI ptt file) compare
BT3760 -5.2 -5.1 arginosuccinate synthetase (EC 6.3.4.5) (from data) compare
BT1374 -5.2 -3.6 diaminopimelate decarboxylase (EC 4.1.1.20) (from data) compare
BT2403 -5.2 -9.3 aspartate kinase / homoserine dehydrogenase (EC 2.7.2.4; EC 1.1.1.3) (from data) compare
BT1153 -5.1 -3.6 phosphoserine aminotransferase (NCBI ptt file) compare
BT0532 -5.1 -3.5 anthranilate synthase component I (NCBI ptt file) compare
BT2077 -5.0 -4.9 acetolactate synthase large subunit (NCBI ptt file) compare
BT1858 -5.0 -6.0 (R)-citramalate synthase (EC 2.3.1.182) (from data) compare
BT3717 -5.0 -4.9 N-succinylornithine carbamoyltransferase (EC 2.1.3.11) (from data) compare
BT0528 -5.0 -4.9 phosphoribosylanthranilate isomerase (EC 5.3.1.24) (from data) compare
BT2076 -5.0 -7.6 acetohydroxybutanoate synthase regulatory subunit (EC 2.2.1.6) (from data) compare
BT3936 -5.0 -4.8 prephenate and/or arogenate dehydratase (EC 4.2.1.51) (from data) compare
BT0530 -5.0 -3.4 anthranilate phosphoribosyltransferase (EC 2.4.2.18) (from data) compare
BT0201 -4.9 -3.4 histidinol dehydrogenase (NCBI ptt file) compare
BT1377 -4.9 -4.8 phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase (NCBI ptt file) compare
BT3719 -4.9 -6.7 glutamate 5-kinase (EC 2.7.2.11) (from data) compare
BT1861 -4.9 -7.5 2-isopropylmalate synthase (EC 2.3.3.13) (from data) compare
BT1379 -4.9 -4.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
BT3718 -4.8 -14.5 gamma-glutamyl phosphate reductase (NCBI ptt file) compare
BT2415 -4.8 -15.2 aspartate aminotransferase (NCBI ptt file) compare
BT1860 -4.7 -3.3 3-isopropylmalate dehydratase large subunit (NCBI ptt file) compare
BT1152 -4.7 -3.2 D-3-phosphoglycerate dehydrogenase (NCBI ptt file) compare
BT1419 -4.7 -3.2 hypothetical protein (NCBI ptt file) compare
BT3361 -4.6 -11.9 erythronate-4-phosphate dehydrogenase (NCBI ptt file) compare
BT4211 -4.6 -3.2 putative phosphoribosylformylglycinamidine cyclo-ligase (NCBI ptt file) compare
BT1970 -4.5 -12.7 glutamate dehydrogenase (NCBI ptt file) compare
BT0527 -4.4 -4.3 tryptophan synthase alpha chain (NCBI ptt file) compare
BT0700 -4.4 -5.2 GTP pyrophosphokinase (NCBI ptt file) compare
BT2686 -4.3 -18.4 putative cation efflux transporter (NCBI ptt file) compare
BT2003 -4.3 -2.5 putative membrane peptidase (NCBI ptt file) compare
BT0202 -4.3 -8.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
BT2688 -4.3 -9.0 outer membrane efflux protein (NCBI ptt file) compare
BT0875 -4.1 -7.4 beta-ureidopropionase (NCBI ptt file) compare
BT2687 -4.1 -11.7 cation efflux system protein (NCBI ptt file) compare
BT0529 -4.1 -2.8 indole-3-glycerol phosphate synthase (NCBI ptt file) compare
BT1420 -4.1 -4.8 conserved hypothetical protein (NCBI ptt file) compare
BT4699 -4.0 -3.9 putative hydrolase, haloacid dehalogenase-like hydrolase (NCBI ptt file) compare
BT1270 -3.9 -8.4 putative Na+/H+ antiporter (NCBI ptt file) compare
BT0533 -3.9 -3.8 tryptophan synthase beta chain (NCBI ptt file) compare
BT1733 -3.9 -5.4 putative phosphoribosylformylglycinamidine synthase (NCBI ptt file) compare
BT0531 -3.9 -4.4 anthranilate synthase component II (NCBI ptt file) compare
BT3164 -3.9 -14.0 quinolinate synthetase A (NCBI ptt file) compare
BT0200 -3.9 -5.3 ATP phosphoribosyltransferase (NCBI ptt file) compare
BT0203 -3.9 -3.8 histidine biosynthesis bifunctional protein hisB (NCBI ptt file) compare
BT2080 -3.9 -3.8 L-cysteine desulfidase cdsB (from data) compare
BT2129 -3.9 -8.6 aspartate--ammonia ligase (NCBI ptt file) compare
BT0876 -3.8 -3.1 conserved hypothetical protein (NCBI ptt file) compare
BT2062 -3.8 -10.0 6-phosphofructokinase (NCBI ptt file) compare
BT3394 -3.7 -14.6 putative arginine decarboxylase (NCBI ptt file) compare
BT3184 -3.7 -20.5 L-aspartate oxidase (NCBI ptt file) compare
BT3320 -3.6 -6.1 dihydrodipicolinate reductase (NCBI ptt file) compare
BT1336 -3.6 -5.8 putative translation initiation inhibitor (NCBI ptt file) compare
BT1476 -3.5 -6.2 aspartate aminotransferase (NCBI ptt file) compare
BT0738 -3.5 -5.3 serine hydroxymethyltransferase (NCBI ptt file) compare
BT1375 -3.3 -12.6 aspartokinase (NCBI ptt file) compare
BT1442 -3.3 -9.3 adenosylmethionine-8-amino-7-oxononanoate aminotransferase (NCBI ptt file) compare
BT0674 -3.3 -4.8 carboxynorspermidine decarboxylase (NCBI ptt file) compare
BT3935 -3.2 -7.9 aminotransferase (NCBI ptt file) compare
BT0652 -3.2 -2.8 putative thiamine-phosphate pyrophosphorylase (NCBI ptt file) compare
BT4339 -3.2 -5.2 glutamine synthetase (NCBI ptt file) compare
BT1446 -3.1 -9.2 dethiobiotin synthetase (NCBI ptt file) compare
BT4644 -3.0 -5.0 putative anti-sigma factor (NCBI ptt file) compare
BT1381 -2.9 -7.6 formyltetrahydrofolate deformylase (NCBI ptt file) compare
BT1747 -2.9 -10.6 pyruvate-flavodoxin oxidoreductase (NCBI ptt file) compare
BT3845 -2.9 -3.9 inosine-5'-monophosphate dehydrogenase (NCBI ptt file) compare
BT1976 -2.9 -2.6 hypothetical protein (NCBI ptt file) compare
BT1378 -2.9 -3.6 imidazole glycerol phosphate synthase subunit hisF (NCBI ptt file) compare
BT1445 -2.8 -6.2 putative biotin synthesis protein bioC (NCBI ptt file) compare
BT1443 -2.8 -7.4 8-amino-7-oxononanoate synthase (NCBI ptt file) compare
BT2845 -2.7 -9.7 conserved hypothetical protein (NCBI ptt file) compare
BT4382 -2.7 -5.0 hypothetical protein (NCBI ptt file) compare
BT2742 -2.7 -2.5 integrase, site-specific recombinase (NCBI ptt file) compare
BT4612 -2.7 -7.1 conserved hypothetical protein (NCBI ptt file) compare
BT3762 -2.6 -4.6 arginine repressor, transcriptional regulator of arginine metabolism (NCBI ptt file) compare
BT0747 -2.6 -1.8 putative phosphatidylinositol-4-phosphate 5-kinase (NCBI ptt file) compare
BT1844 -2.6 -4.8 transcriptional regulator, putative iron uptake regulation protein (NCBI ptt file) compare
BT4557 -2.5 -10.3 hypothetical protein (NCBI ptt file) compare
BT3370 -2.5 -5.8 putative glycosyltransferase yibD (NCBI ptt file) compare
p5482_02 -2.5 -6.9 hypothetical protein (NCBI) compare
BT1380 -2.4 -2.3 imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) compare
BT2173 -2.4 -8.4 hypothetical protein (NCBI ptt file) compare
BT4563 -2.3 -3.5 hypothetical protein (NCBI ptt file) compare
BT0647 -2.3 -3.3 thiamine phosphate pyrophosphorylase (NCBI ptt file) compare
BT4322 -2.3 -3.3 conserved hypothetical protein, with a diacylglycerol kinase catalytic domain (NCBI ptt file) compare
BT0828 -2.2 -3.2 dTDP-4-dehydrorhamnose 3,5-epimerase (NCBI ptt file) compare
BT_2008 -2.2 -1.7 hypothetical protein (RefSeq) compare
BT2546 -2.2 -2.3 transcriptional regulator (NCBI ptt file) compare
BT3035 -2.2 -10.8 carboxy-terminal processing protease precursor (NCBI ptt file) compare
BT0648 -2.2 -5.3 molybdopterin biosynthesis protein (NCBI ptt file) compare
BT3369 -2.2 -4.3 putative glycosyltransferase (NCBI ptt file) compare
BT0704 -2.1 -1.5 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) compare
BT0638 -2.1 -6.9 putative methionine aminopeptidase A (NCBI ptt file) compare
BT3912 -2.1 -3.7 conserved hypothetical protein (NCBI ptt file) compare
BT3866 -2.1 -13.6 ammonium-dependent carbamoyl phosphate synthetase CarB2 (EC 6.3.4.16) (from data) compare
BT1222 -2.1 -3.7 6-phosphogluconate dehydrogenase,decarboxylating (NCBI ptt file) compare
BT1867 -2.0 -3.9 hypothetical protein (NCBI ptt file) compare
BT1972 -1.9 -9.6 phosphoenolpyruvate synthase/pyruvate phosphate dikinase (NCBI ptt file) compare
BT1326 -1.9 -2.5 TPR-domain containing protein (NCBI ptt file) compare
BT2689 -1.9 -6.2 conserved hypothetical protein (NCBI ptt file) compare
BT1363 -1.9 -2.2 DNA Pol III Epsilon Chain (NCBI ptt file) compare
BT0790 -1.9 -3.1 phosphomethylpyrimidine kinase (NCBI ptt file) compare
BT3074 -1.8 -4.8 conserved hypothetical protein (NCBI ptt file) compare
BT3920 -1.8 -1.3 conserved hypothetical protein (NCBI ptt file) compare
BT4206 -1.7 -1.6 UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (NCBI ptt file) compare
BT1526 -1.7 -4.1 myo-inositol-1-phosphate synthase (NCBI ptt file) compare
BT1444 -1.7 -2.7 conserved hypothetical protein (NCBI ptt file) compare
BT0418 -1.7 -2.4 outer membrane porin F precursor (NCBI ptt file) compare
BT2844 -1.7 -7.6 conserved hypothetical protein (NCBI ptt file) compare
BT2843 -1.7 -2.4 integrase (NCBI ptt file) compare
BT2781 -1.7 -4.1 putative mannose-1-phosphate guanylyltransferase (NCBI ptt file) compare
BT4102 -1.6 -2.2 putative Sec-independent protein translocase (NCBI ptt file) compare
BT4674 -1.6 -5.3 hypothetical protein (NCBI ptt file) compare
BT3712 -1.6 -3.4 ribosomal large subunit pseudouridine synthase D (NCBI ptt file) compare
BT3911 -1.6 -4.2 malate dehydrogenase (NCBI ptt file) compare
BT2172 -1.6 -9.6 putative outer membrane protein, probably involved in nutrient binding (NCBI ptt file) compare
BT1557 -1.6 -2.3 hypothetical protein (NCBI ptt file) compare
BT2071 -1.6 -5.5 isocitrate dehydrogenase [NADP] (NCBI ptt file) compare
BT0249 -1.6 -2.7 5-methyltetrahydrofolate--homocysteine methyltransferase or methionine synthase (NCBI ptt file) compare
BT3770 -1.6 -2.0 transcriptional regulator (NCBI ptt file) compare
BT1894 -1.6 -6.1 TPR-repeat-containing proteins (NCBI ptt file) compare
BT3481 -1.5 -1.8 putative glutaminase A (NCBI ptt file) compare
BT1555 -1.5 -4.0 dioxygenase, related to 2-nitropropane dioxygenase (NCBI ptt file) compare
BT0650 -1.5 -5.4 thiamine biosynthesis protein ThiC (NCBI ptt file) compare
BT1234 -1.5 -2.9 conserved hypothetical protein (NCBI ptt file) compare
BT3554 -1.5 -4.0 conserved hypothetical protein (NCBI ptt file) compare
BT3268 -1.4 -3.7 glucose-inhibited division protein A (NCBI ptt file) compare
BT3894 -1.4 -3.7 putative methyltransferase (NCBI ptt file) compare
BT4310 -1.4 -8.4 NADPH-dependent glutamate synthase small chain (NCBI ptt file) compare
BT1851 -1.4 -3.6 TPR-repeat-containing protein (NCBI ptt file) compare
BT0151 -1.4 -1.7 hypothetical protein (NCBI ptt file) compare
BT3372 -1.4 -6.2 glycosyltransferase (NCBI ptt file) compare
BT1220 -1.4 -3.1 6-phosphogluconolactonase (NCBI ptt file) compare
BT3371 -1.4 -3.4 putative glycosyltransferase yibD (NCBI ptt file) compare
BT4618 -1.4 -2.1 conserved hypothetical protein (NCBI ptt file) compare
BT1680 -1.3 -2.4 putative NADH dehydrogenase/NAD(P)H nitroreductase (NCBI ptt file) compare
BT4570 -1.3 -3.9 hypothetical protein (NCBI ptt file) compare
BT3724 -1.3 -3.9 cationic outer membrane protein precursor (NCBI ptt file) compare
BT1905 -1.3 -2.3 conserved hypothetical protein (NCBI ptt file) compare
BT1752 -1.3 -2.1 hypothetical protein (NCBI ptt file) compare
BT1608 -1.3 -5.3 capsule biosynthesis protein capA (NCBI ptt file) compare
BT4193 -1.2 -7.0 dipeptidyl peptidase IV (NCBI ptt file) compare
BT2417 -1.2 -1.0 conserved hypothetical protein (NCBI ptt file) compare
BT3224 -1.2 -4.3 putative lysine decarboxylase (NCBI ptt file) compare
BT3368 -1.2 -1.6 putative glycosyltransferase (NCBI ptt file) compare
BT4551 -1.2 -2.7 putative GTPase, ThdF family (NCBI ptt file) compare
BT1679 -1.2 -2.3 hypothetical protein (NCBI ptt file) compare
BT3840 -1.2 -2.4 putative RNA-binding protein rbpA (NCBI ptt file) compare
BT3286 -1.2 -2.0 conserved hypothetical protein (NCBI ptt file) compare
BT2072 -1.2 -5.3 aconitate hydratase (NCBI ptt file) compare
BT3376 -1.2 -5.3 nucleotide sugar transaminase (NCBI ptt file) compare
BT2170 -1.2 -2.9 hypothetical protein (NCBI ptt file) compare
BT3373 -1.2 -2.9 spermidine n1-acetyltransferase (NCBI ptt file) compare
BT1804 -1.1 -2.6 electron transfer flavoprotein beta-subunit (NCBI ptt file) compare
BT4590 -1.1 -2.3 conserved hypothetical protein (NCBI ptt file) compare
BT0820 -1.1 -2.4 conserved hypothetical protein (NCBI ptt file) compare
BT3374 -1.1 -4.7 putative carbamoyl-phosphate-synthetase (NCBI ptt file) compare
BT0241 -1.1 -1.7 hypothetical protein (NCBI ptt file) compare
BT3210 -1.1 -2.5 cell division protein FtsX (NCBI ptt file) compare
BT1376 -1.1 -2.5 putative ATP-binding protein involved in cell division (NCBI ptt file) compare
BT4333 -1.1 -3.4 hypothetical protein (NCBI ptt file) compare
BT4258 -1.1 -4.7 putative 5-formyltetrahydrofolate cyclo-ligase (NCBI ptt file) compare
BT0649 -1.1 -2.4 thiamine biosynthesis protein ThiH (NCBI ptt file) compare
BT0771 -1.1 -4.4 1,4-alpha-glucan branching enzyme (isoamylase or pullulanase type II) (NCBI ptt file) compare
BT3812 -1.1 -2.9 phosphoribosylaminoimidazole carboxy formyl formyltransferase; inosine-monophosphate cyclohydrolase; bifunctional purine biosynthesis protein purH (NCBI ptt file) compare
BT0722 -1.1 -2.6 conserved hypothetical protein, putative surface protein, function unknown (NCBI ptt file) compare
BT1240 -1.1 -3.5 conserved hypothetical protein (NCBI ptt file) compare
BT1256 -1.1 -1.2 conserved hypothetical protein (NCBI ptt file) compare
BT4328 -1.1 -1.0 conserved hypothetical protein (NCBI ptt file) compare
BT0912 -1.0 -1.6 DNA-binding protein HU (NCBI ptt file) compare
BT1524 -1.0 -1.4 hypothetical protein (NCBI ptt file) compare
BT3727 -1.0 -2.2 hypothetical protein (NCBI ptt file) compare
BT3578 -1.0 -4.0 hypothetical protein (NCBI ptt file) compare
BT4003 -1.0 -1.9 stationary-phase survival protein SurE (NCBI ptt file) compare
BT1979 -1.0 -2.6 Meso-diaminopimelate D-dehydrogenase (NCBI ptt file) compare
BT1641 -1.0 -1.5 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT1854 -1.0 -1.0 putative membrane-associated phospholipid phosphatase (NCBI ptt file) compare


Specific Phenotypes

For 2 genes in this experiment

For stress Chenodeoxycholic acid in Bacteroides thetaiotaomicron VPI-5482

For stress Chenodeoxycholic acid across organisms