Experiment set12IT014 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

Varel_Bryant_medium_Glucose with Bile salts 0.125 mg/mL; pH 6

200 most detrimental genes:

  gene name fitness t score description  
BT3642 +1.8 11.9 Na+-dependent transporter (NCBI ptt file) compare
BT1169 +1.3 3.2 hypothetical protein (NCBI ptt file) compare
BT0581 +1.1 2.6 putative acetyltransferase, GNAT family (NCBI ptt file) compare
BT3503 +1.1 2.1 glutaminase A (NCBI ptt file) compare
BT4453 +1.0 1.5 6-pyruvoyl-tetrahydropterin synthase (NCBI ptt file) compare
BT1947 +0.9 2.1 hypothetical protein (NCBI ptt file) compare
BT0869 +0.9 1.7 hypothetical protein (NCBI ptt file) compare
BT0007 +0.9 2.4 hypothetical protein (NCBI ptt file) compare
BT1229 +0.9 1.9 conserved hypothetical protein, putative membrane protein (NCBI ptt file) compare
BT3213 +0.9 1.9 tRNA pseudouridine synthase B (NCBI ptt file) compare
BT0400 +0.8 2.3 putative tyrosine-protein kinase in capsular polysaccharide biosynthesis region (NCBI ptt file) compare
BT0878 +0.8 1.6 ABC transporter, ATP-binding protein (NCBI ptt file) compare
BT0699 +0.8 2.8 putative sugar transporter (NCBI ptt file) compare
BT3839 +0.8 1.6 ABC transporter ATP-binding protein (NCBI ptt file) compare
BT3639 +0.8 4.8 ThiF family protein, putative dinucleotide-utilizing enzyme involved in molybdopterin and thiamine biosynthesis (NCBI ptt file) compare
BT1385 +0.8 4.0 transcriptional regulator (NCBI ptt file) compare
BT0567 +0.8 2.8 putative protein involved in barrier function of the cell envelope (NCBI ptt file) compare
BT1854 +0.8 1.0 putative membrane-associated phospholipid phosphatase (NCBI ptt file) compare
BT0795 +0.8 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT1516 +0.7 2.9 replicative DNA helicase (NCBI ptt file) compare
BT1612 +0.7 3.1 hypothetical protein (NCBI ptt file) compare
BT2853 +0.7 1.8 hypothetical protein (NCBI ptt file) compare
BT1808 +0.7 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT0847 +0.7 2.5 hypothetical protein (NCBI ptt file) compare
BT0723 +0.7 1.5 hypothetical protein (NCBI ptt file) compare
BT0389 +0.7 2.1 putative galactoside acetyltransferase (NCBI ptt file) compare
BT1741 +0.7 1.6 hypothetical protein (NCBI ptt file) compare
BT0902 +0.7 2.0 hypothetical protein (NCBI ptt file) compare
BT3392 +0.7 3.3 nitroreductase (NCBI ptt file) compare
BT4646 +0.7 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT4760 +0.7 3.1 hypothetical protein (NCBI ptt file) compare
BT0080 +0.7 2.6 hypothetical protein (NCBI ptt file) compare
BT0776 +0.7 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT1505 +0.7 2.3 hypothetical protein (NCBI ptt file) compare
BT2979 +0.7 2.4 conserved hypothetical protein, putative membrane protein (NCBI ptt file) compare
BT1805 +0.7 1.5 electron transfer flavoprotein alpha-subunit (NCBI ptt file) compare
BT0427 +0.7 1.6 xanthine phosphoribosyltransferase (NCBI ptt file) compare
BT3643 +0.7 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT2302 +0.6 0.9 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT2280 +0.6 1.6 hypothetical protein (NCBI ptt file) compare
BT0119 +0.6 1.6 hypothetical protein (NCBI ptt file) compare
BT0170 +0.6 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT0321 +0.6 1.2 cytidine/deoxycytidylate deaminase (NCBI ptt file) compare
BT2799 +0.6 4.0 putative PfkB family carbohydrate kinase (NCBI ptt file) compare
BT4097 +0.6 1.8 Trk system K+ uptake protein trkH (NCBI ptt file) compare
BT3801 +0.6 2.3 rteB, two-component system response regulator (NCBI ptt file) compare
BT1200 +0.6 2.3 hypothetical protein (NCBI ptt file) compare
BT2490 +0.6 1.5 hypothetical protein (NCBI ptt file) compare
BT1990 +0.6 1.4 hypothetical protein (NCBI ptt file) compare
BT1964 +0.6 2.4 hypothetical protein (NCBI ptt file) compare
BT1018 +0.6 2.4 polygalacturonase (Pectinase) (NCBI ptt file) compare
BT1011 +0.6 2.6 conserved hypothetical protein (NCBI ptt file) compare
BT0397 +0.6 0.9 conserved hypothetical protein (NCBI ptt file) compare
BT1758 +0.6 2.5 fructose transporter (from data) compare
BT0593 +0.6 1.3 conserved hypothetical protein (NCBI ptt file) compare
BT4025 +0.6 1.6 hypothetical protein (NCBI ptt file) compare
BT0429 +0.6 1.2 indolepyruvate oxidoreductase subunit iorB (NCBI ptt file) compare
BT3509 +0.6 3.2 conserved hypothetical protein (NCBI ptt file) compare
BT2018 +0.6 2.7 conserved hypothetical protein (NCBI ptt file) compare
BT0932 +0.6 1.4 hypothetical protein (NCBI ptt file) compare
BT2142 +0.5 0.9 conserved hypothetical protein, with a conserved domain (NCBI ptt file) compare
BT1569 +0.5 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT4468 +0.5 2.9 conserved hypothetical protein (NCBI ptt file) compare
BT4730 +0.5 2.0 hypothetical protein (NCBI ptt file) compare
BT0153 +0.5 2.3 hypothetical protein (NCBI ptt file) compare
BT1202 +0.5 1.0 UDP-N-acetylglucosamine 2-epimerase (NCBI ptt file) compare
BT1997 +0.5 2.1 hypothetical protein (NCBI ptt file) compare
BT0015 +0.5 1.4 rteB, two-component system response regulator (NCBI ptt file) compare
BT4031 +0.5 1.7 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT0880 +0.5 1.1 hypothetical protein (NCBI ptt file) compare
BT4018 +0.5 1.2 hypothetical protein (NCBI ptt file) compare
BT1226 +0.5 2.7 putative long-chain-fatty-acid--CoA ligase (NCBI ptt file) compare
BT2281 +0.5 1.2 hypothetical protein (NCBI ptt file) compare
BT0341 +0.5 3.2 Na+/glucose cotransporter (NCBI ptt file) compare
BT1320 +0.5 2.4 putative transcriptional regulator, phosphate uptake regulation (NCBI ptt file) compare
BT1104 +0.5 0.9 small heat shock protein (NCBI ptt file) compare
BT0238 +0.5 2.4 transcriptional regulator (NCBI ptt file) compare
BT1536 +0.5 1.9 ABC transporter permease (NCBI ptt file) compare
BT1667 +0.5 1.2 hypothetical protein (NCBI ptt file) compare
BT0056 +0.5 3.0 putative glycosyltransferase (NCBI ptt file) compare
BT0501 +0.5 1.6 hypothetical protein (NCBI ptt file) compare
BT1322 +0.5 2.2 putative ABC transporter permease protein (NCBI ptt file) compare
BT0508 +0.5 1.3 ABC transporter ATP-binding protein (NCBI ptt file) compare
BT0972 +0.5 1.0 putative oxidoreductase (NCBI ptt file) compare
BT2031 +0.5 2.2 hypothetical protein (NCBI ptt file) compare
BT0148 +0.5 2.2 putative hemolysin (NCBI ptt file) compare
BT3869 +0.5 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT0984 +0.5 2.7 hypothetical protein (NCBI ptt file) compare
BT0302 +0.5 1.5 hypothetical protein (NCBI ptt file) compare
BT3232 +0.5 0.9 gluconate 5-dehydrogenase (NCBI ptt file) compare
BT4503 +0.5 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT0027 +0.5 2.5 putative transposase (NCBI ptt file) compare
BT2413 +0.5 3.4 homoserine O-succinyltransferase (NCBI ptt file) compare
BT0418 +0.5 1.4 outer membrane porin F precursor (NCBI ptt file) compare
BT1203 +0.5 1.3 putative UDP-N-acetylglucosamine 2-epimerase (NCBI ptt file) compare
BT4666 +0.5 1.4 putative K+ uptake system protein (NCBI ptt file) compare
BT0493 +0.5 1.2 hypothetical protein (NCBI ptt file) compare
BT0877 +0.5 1.3 ferredoxin domain containing protein (NCBI ptt file) compare
BT1291 +0.5 2.3 spermidine/putrescine transport ATP-binding protein (NCBI ptt file) compare
BT0737 +0.5 2.2 formate--tetrahydrofolate ligase (NCBI ptt file) compare
BT1402 +0.5 1.4 iron-sulfur flavoprotein (NCBI ptt file) compare
BT0637 +0.5 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT1172 +0.4 1.8 DNA primase/helicase (NCBI ptt file) compare
BT0844 +0.4 1.1 hypothetical protein (NCBI ptt file) compare
BT0256 +0.4 1.8 hypothetical protein (NCBI ptt file) compare
BT1138 +0.4 1.3 transposase (NCBI ptt file) compare
BT0516 +0.4 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT2555 +0.4 2.0 hypothetical protein (NCBI ptt file) compare
BT4271 +0.4 1.1 hypothetical protein (NCBI ptt file) compare
BT3628 +0.4 1.4 conserved hypothetical protein (NCBI ptt file) compare
BT0291 +0.4 2.1 integrase (NCBI ptt file) compare
BT1817 +0.4 1.9 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT4734 +0.4 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT2136 +0.4 2.2 putative purple acid phosphatase (NCBI ptt file) compare
BT3730 +0.4 0.9 putative regulatory protein (NCBI ptt file) compare
BT1262 +0.4 0.9 putative transcriptional regulator (NCBI ptt file) compare
BT2597 +0.4 1.5 hypothetical protein (NCBI ptt file) compare
BT1577 +0.4 1.5 pyridoxamine 5'-phosphate oxidase (NCBI ptt file) compare
BT1793 +0.4 2.0 integrase protein (NCBI ptt file) compare
BT0432 +0.4 1.6 putative endonuclease BB0411 (NCBI ptt file) compare
BT3249 +0.4 1.6 putative zinc ABC transporter, zinc-binding protein (NCBI ptt file) compare
BT4033 +0.4 1.2 hypothetical protein (NCBI ptt file) compare
BT1286 +0.4 2.6 putative two-component system response regulator (NCBI ptt file) compare
BT0767 +0.4 2.1 putative para-aminobenzoate synthase component I (NCBI ptt file) compare
BT1583 +0.4 0.8 putative protein disulfide isomerase (NCBI ptt file) compare
BT0792 +0.4 1.7 xylulokinase (EC 2.7.1.17) (from data) compare
BT1803 +0.4 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT0860 +0.4 1.0 putative ABC transporter ATP-binding protein (NCBI ptt file) compare
BT2537 +0.4 1.8 hypothetical protein (NCBI ptt file) compare
BT3077 +0.4 0.8 ribonuclease R (NCBI ptt file) compare
BT1367 +0.4 1.5 hydrolase, metal-dependent (NCBI ptt file) compare
BT0705 +0.4 1.8 hypothetical protein (NCBI ptt file) compare
BT0409 +0.4 1.5 putative short-chain dehydrogenase (NCBI ptt file) compare
BT3819 +0.4 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT0783 +0.4 0.5 hypothetical protein (NCBI ptt file) compare
BT3457 +0.4 1.6 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT4184 +0.4 2.2 phosphoglycolate phosphatase (NCBI ptt file) compare
BT1532 +0.4 2.3 ABC transporter permease (NCBI ptt file) compare
BT0843 +0.4 1.7 hypothetical protein (NCBI ptt file) compare
BT2539 +0.4 1.5 rubredoxin (NCBI ptt file) compare
BT4752 +0.4 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT0853 +0.4 1.5 putative methyltransferase (NCBI ptt file) compare
BT1633 +0.4 1.8 mannose-1-phosphate guanyltransferase (NCBI ptt file) compare
BT1201 +0.4 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT2181 +0.4 1.6 transcriptional regulator (NCBI ptt file) compare
BT3772 +0.4 1.1 ribosomal large subunit pseudouridine synthase D (NCBI ptt file) compare
BT2034 +0.4 1.6 two-component system response regulator (NCBI ptt file) compare
BT0155 +0.4 2.2 putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (NCBI ptt file) compare
BT2844 +0.4 2.7 conserved hypothetical protein (NCBI ptt file) compare
BT0505 +0.4 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT4737 +0.4 1.6 pyruvate formate-lyase activating enzyme (NCBI ptt file) compare
BT1535 +0.4 1.0 ABC transporter ATP-binding protein (NCBI ptt file) compare
BT0619 +0.4 0.9 Na+-transporting NADH:ubiquinone oxidoreductase, Electron transport complex protein rnfD (NCBI ptt file) compare
BT0073 +0.4 1.8 putative ABC transporter, ATP-binding protein (NCBI ptt file) compare
BT4545 +0.4 1.2 hypothetical protein (NCBI ptt file) compare
BT1945 +0.4 1.2 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT3339 +0.4 2.7 RND efflux system for fusidic acid, chlorpromazine, and thioridazine, membrane fusion component (from data) compare
BT0411 +0.4 1.4 CysQ, sulfite synthesis pathway protein (NCBI ptt file) compare
BT0353 +0.4 1.6 putative sugar epimerase/aldolase (NCBI ptt file) compare
BT0113 +0.4 1.3 hypothetical protein (NCBI ptt file) compare
BT4719 +0.4 1.7 hypothetical protein (NCBI ptt file) compare
BT0184 +0.4 1.1 uridine kinase (uridine monophosphokinase) (NCBI ptt file) compare
BT4738 +0.4 2.4 formate acetyltransferase (NCBI ptt file) compare
BT3852 +0.4 2.0 major outer membrane protein OmpA (NCBI ptt file) compare
BT1316 +0.4 0.8 putative NADH dehydrogenase/NAD(P)H nitroreductase (NCBI ptt file) compare
BT1199 +0.4 1.8 putative protease (NCBI ptt file) compare
BT4386 +0.4 0.7 hypoxanthine-guanine phosphoribosyltransferase (NCBI ptt file) compare
BT0216 +0.4 1.0 putative rubrerythrin (NCBI ptt file) compare
BT0010 +0.4 1.3 hypothetical protein (NCBI ptt file) compare
BT0077 +0.4 1.0 conserved hypothetical protein (NCBI ptt file) compare
BT4466 +0.4 0.7 hypothetical protein (NCBI ptt file) compare
BT0703 +0.4 1.4 hypothetical protein (NCBI ptt file) compare
BT0463 +0.4 1.2 glucose-1-phosphate thymidylyltransferase (NCBI ptt file) compare
BT4242 +0.4 1.5 putative transporter (NCBI ptt file) compare
BT3921 +0.4 1.2 hypothetical protein (NCBI ptt file) compare
BT0720 +0.4 2.3 hypothetical protein (NCBI ptt file) compare
BT2336 +0.4 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT0063 +0.4 1.0 hypothetical protein (NCBI ptt file) compare
BT4103 +0.4 1.4 putative Sec-independent protein translocase (NCBI ptt file) compare
BT3038 +0.4 2.3 putative anti-sigma factor (NCBI ptt file) compare
BT4429 +0.4 1.2 putative pteridine-dependent dioxygenase (NCBI ptt file) compare
BT1531 +0.4 2.5 two-component system sensor histidine kinase (NCBI ptt file) compare
BT3882 +0.4 0.5 putative DNA binding protein (NCBI ptt file) compare
BT3262 +0.4 1.5 hypothetical protein (NCBI ptt file) compare
BT3899 +0.4 1.8 transcriptional regulator (NCBI ptt file) compare
BT1126 +0.4 0.5 mobilization protein BmgA (NCBI ptt file) compare
BT0639 +0.4 1.2 conserved hypothetical protein (NCBI ptt file) compare
BT4232 +0.3 1.8 hypothetical protein (NCBI ptt file) compare
BT0550 +0.3 1.4 putative glycerophosphodiester phosphodiesterase (NCBI ptt file) compare
BT1274 +0.3 1.4 L-fuculose-1-phosphate aldolase FucA (4.1.2.17); D-ribulose-1-phosphate aldolase (from data) compare
BT1621 +0.3 1.8 beta-hexosaminidase precursor (NCBI ptt file) compare
BT4302 +0.3 1.1 conserved hypothetical protein (NCBI ptt file) compare
BT1289 +0.3 1.5 putrescine transport system permease protein potI (NCBI ptt file) compare
BT0338 +0.3 1.6 conserved hypothetical protein (NCBI ptt file) compare
BT0586 +0.3 1.6 hypothetical protein (NCBI ptt file) compare
BT2028 +0.3 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT2122 +0.3 0.6 lysyl-tRNA synthetase (NCBI ptt file) compare
BT1561 +0.3 0.7 hypothetical protein (NCBI ptt file) compare
BT1218 +0.3 1.7 conserved hypothetical protein, with conserved domain (NCBI ptt file) compare
BT1468 +0.3 1.6 putative outer membrane efflux protein (NCBI ptt file) compare


Specific Phenotypes

None in this experiment

For Bacteroides thetaiotaomicron VPI-5482 in stress experiments

For stress Bile salts across organisms