Experiment set12IT010 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_glucose with 2,2'-Dipyridyl 400 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS20895 -7.1 -6.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04465 -6.3 -7.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS09755 -5.3 -10.8 phosphoserine transaminase compare
BWI76_RS04470 -5.3 -9.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS23920 -5.3 -9.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00400 -5.1 -3.5 glutamine synthetase compare
BWI76_RS04160 -5.0 -7.5 phosphoserine phosphatase compare
BWI76_RS07070 -5.0 -8.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS01615 -4.8 -10.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS09645 -4.7 -2.1 thioredoxin-disulfide reductase compare
BWI76_RS02995 -4.5 -12.6 aspartate carbamoyltransferase compare
BWI76_RS11965 -4.4 -5.2 orotidine-5'-phosphate decarboxylase compare
BWI76_RS21475 -4.3 -6.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS21265 -4.3 -13.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS23360 -4.2 -5.9 diaminopimelate decarboxylase compare
BWI76_RS04645 -4.1 -8.3 3-dehydroquinase compare
BWI76_RS16980 -3.9 -6.2 bifunctional cysteine desulfurase/selenocysteine lyase compare
BWI76_RS18950 -3.9 -5.9 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS23230 -3.9 -2.7 exodeoxyribonuclease V subunit beta compare
BWI76_RS07065 -3.9 -8.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS01610 -3.8 -10.4 phosphoribosylamine--glycine ligase compare
BWI76_RS10990 -3.8 -5.8 dihydroorotase compare
BWI76_RS20350 -3.8 -5.1 amidophosphoribosyltransferase compare
BWI76_RS05835 -3.7 -4.2 gamma-glutamyl-phosphate reductase compare
BWI76_RS22690 -3.6 -5.5 adenylyl-sulfate kinase compare
BWI76_RS04250 -3.6 -9.2 homoserine kinase compare
BWI76_RS20355 -3.6 -4.8 colicin V production protein compare
BWI76_RS08385 -3.5 -4.9 citrate (Si)-synthase compare
BWI76_RS20965 -3.5 -6.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS17000 -3.5 -5.5 Fe-S cluster assembly scaffold SufA compare
BWI76_RS06905 -3.5 -10.4 Cu+ exporting ATPase compare
BWI76_RS23240 -3.3 -4.5 exonuclease V subunit gamma compare
BWI76_RS23265 -3.3 -5.3 hypothetical protein compare
BWI76_RS27385 -3.2 -10.0 orotate phosphoribosyltransferase compare
BWI76_RS22765 -3.2 -14.0 sulfite reductase subunit alpha compare
BWI76_RS15825 -3.2 -2.0 hypothetical protein compare
BWI76_RS00855 -3.2 -12.7 argininosuccinate lyase compare
BWI76_RS07725 -3.1 -2.4 iron-enterobactin transporter permease compare
BWI76_RS05840 -3.1 -6.3 glutamate 5-kinase compare
BWI76_RS18930 -3.1 -8.8 histidinol-phosphate transaminase compare
BWI76_RS23365 -3.1 -5.4 LysR family transcriptional regulator compare
BWI76_RS20380 -3.1 -2.3 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS22755 -3.0 -7.0 phosphoadenosine phosphosulfate reductase compare
BWI76_RS18940 -3.0 -7.8 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS22760 -3.0 -8.6 sulfite reductase subunit beta compare
BWI76_RS00975 -3.0 -7.9 dihydroxy-acid dehydratase compare
BWI76_RS00845 -3.0 -10.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS26460 -2.9 -6.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS04255 -2.9 -7.3 threonine synthase compare
BWI76_RS00990 -2.9 -10.6 ketol-acid reductoisomerase compare
BWI76_RS23220 -2.9 -8.9 amino-acid N-acetyltransferase compare
BWI76_RS18935 -2.8 -8.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS17720 -2.8 -1.8 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS25645 -2.8 -9.0 shikimate dehydrogenase compare
BWI76_RS05200 -2.8 -4.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS09910 -2.8 -16.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS02530 -2.8 -3.3 tRNA dimethylallyltransferase compare
BWI76_RS04245 -2.8 -14.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS00805 -2.8 -8.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS08605 -2.8 -2.4 phosphoglyceromutase compare
BWI76_RS03010 -2.6 -9.4 ornithine carbamoyltransferase compare
BWI76_RS00850 -2.6 -9.5 acetylglutamate kinase compare
BWI76_RS00980 -2.6 -11.4 PLP-dependent threonine dehydratase compare
BWI76_RS25115 -2.6 -5.1 argininosuccinate synthase compare
BWI76_RS04240 -2.6 -4.6 thr operon leader peptide compare
BWI76_RS18955 -2.6 -4.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS16975 -2.6 -7.4 cysteine desufuration protein SufE compare
BWI76_RS07705 -2.6 -6.1 enterochelin esterase compare
BWI76_RS00835 -2.6 -13.1 phosphoenolpyruvate carboxylase compare
BWI76_RS18925 -2.5 -6.0 histidinol dehydrogenase compare
BWI76_RS16995 -2.5 -9.7 Fe-S cluster assembly protein SufB compare
BWI76_RS09660 -2.5 -2.3 DNA translocase FtsK compare
BWI76_RS09760 -2.4 -3.6 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS01800 -2.4 -7.5 glucose-6-phosphate isomerase compare
BWI76_RS00785 -2.4 -8.7 cystathionine gamma-synthase compare
BWI76_RS02735 -2.4 -6.6 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS16990 -2.4 -6.6 ABC transporter ATP-binding protein compare
BWI76_RS01655 -2.3 -8.0 homoserine O-succinyltransferase compare
BWI76_RS22805 -2.3 -11.0 GTP diphosphokinase compare
BWI76_RS07740 -2.3 -3.0 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS26455 -2.2 -3.9 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS04665 -2.2 -16.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS17975 -2.1 -4.0 tail-specific protease compare
BWI76_RS20435 -2.1 -2.0 chorismate synthase compare
BWI76_RS07730 -2.1 -2.4 iron-enterobactin transporter membrane protein compare
BWI76_RS18920 -2.1 -4.9 ATP phosphoribosyltransferase compare
BWI76_RS24285 -2.0 -5.4 cystathionine beta-lyase compare
BWI76_RS25425 -2.0 -2.5 arginine repressor compare
BWI76_RS04680 -2.0 -10.3 2-isopropylmalate synthase compare
BWI76_RS04670 -2.0 -10.0 3-isopropylmalate dehydratase large subunit compare
BWI76_RS01385 -2.0 -3.9 potassium transporter compare
BWI76_RS04685 -2.0 -10.6 putative leucine operon leader peptide compare
BWI76_RS04675 -1.9 -5.0 3-isopropylmalate dehydrogenase compare
BWI76_RS16490 -1.9 -3.2 glutaredoxin compare
BWI76_RS26620 -1.9 -2.0 Fe-S biogenesis protein NfuA compare
BWI76_RS26570 -1.9 -4.6 anion permease compare
BWI76_RS26000 -1.9 -6.7 aspartate aminotransferase family protein compare
BWI76_RS01210 -1.8 -3.0 tyrosine recombinase XerC compare
BWI76_RS20650 -1.8 -3.4 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS26055 -1.8 -7.4 siroheme synthase compare
BWI76_RS20995 -1.8 -6.4 RNA degradosome polyphosphate kinase compare
BWI76_RS11860 -1.7 -7.7 anthranilate synthase component I compare
BWI76_RS01630 -1.7 -1.7 16S ribosomal RNA compare
BWI76_RS26200 -1.6 -7.9 starch synthase compare
BWI76_RS11845 -1.6 -5.1 tryptophan synthase subunit beta compare
BWI76_RS27425 -1.6 -2.0 DNA-directed RNA polymerase subunit omega compare
BWI76_RS11840 -1.6 -3.3 tryptophan synthase subunit alpha compare
BWI76_RS08525 -1.6 -2.9 colicin transporter compare
BWI76_RS11850 -1.6 -9.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS27390 -1.6 -2.6 ribonuclease PH compare
BWI76_RS24275 -1.6 -5.6 biopolymer transport protein ExbD compare
BWI76_RS05075 -1.6 -1.8 type II secretion system protein GspG compare
BWI76_RS11855 -1.6 -5.9 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS24885 -1.5 -1.6 PTS galactitol transporter subunit IIB compare
BWI76_RS05015 -1.5 -3.2 transcriptional regulator compare
BWI76_RS12090 -1.5 -2.0 HNH endonuclease compare
BWI76_RS27430 -1.5 -1.5 (p)ppGpp synthetase compare
BWI76_RS04530 -1.4 -2.3 peptidylprolyl isomerase SurA compare
BWI76_RS15350 -1.4 -1.7 hypothetical protein compare
BWI76_RS21465 -1.4 -5.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS13560 -1.4 -1.5 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS20640 -1.4 -3.8 cysteine synthase A compare
BWI76_RS01200 -1.4 -2.0 diaminopimelate epimerase compare
BWI76_RS00345 -1.4 -3.1 protein disulfide oxidoreductase DsbA compare
BWI76_RS19690 -1.3 -3.1 LysR family transcriptional regulator compare
BWI76_RS00970 -1.3 -2.3 branched chain amino acid aminotransferase compare
BWI76_RS21480 -1.3 -4.6 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS01350 -1.2 -1.3 NAD(P)H-flavin reductase compare
BWI76_RS25320 -1.2 -5.7 glutamate synthase compare
BWI76_RS26390 -1.2 -4.9 cell division protein FtsX compare
BWI76_RS09655 -1.2 -4.5 leucine-responsive regulatory protein compare
BWI76_RS00140 -1.2 -1.3 phosphate transport system regulator PhoU compare
BWI76_RS16895 -1.2 -2.4 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS17190 -1.2 -2.0 TonB system transport protein TonB compare
BWI76_RS08530 -1.2 -2.5 protein TolA compare
BWI76_RS24280 -1.2 -3.6 biopolymer transporter ExbB compare
BWI76_RS21165 -1.2 -2.2 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS18065 -1.1 -2.2 DNA polymerase III subunit theta compare
BWI76_RS00760 -1.1 -3.9 cell division protein FtsN compare
BWI76_RS23480 -1.1 -6.9 EAL domain-containing protein compare
BWI76_RS15605 -1.1 -2.0 hypothetical protein compare
BWI76_RS20970 -1.1 -1.9 phosphoribosylglycinamide formyltransferase compare
BWI76_RS26395 -1.1 -3.0 cell division protein FtsE compare
BWI76_RS23885 -1.1 -1.5 2-octaprenylphenol hydroxylase compare
BWI76_RS00180 -1.1 -2.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS19845 -1.1 -3.7 phosphatase compare
BWI76_RS00960 -1.1 -5.7 acetolactate synthase 2 catalytic subunit compare
BWI76_RS04715 -1.0 -1.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS00965 -1.0 -1.2 acetolactate synthase 2 small subunit compare
BWI76_RS12870 -1.0 -2.0 putative phytanoyl-CoA dioxygenase compare
BWI76_RS25315 -1.0 -6.9 glutamate synthase large subunit compare
BWI76_RS23930 -1.0 -5.3 transcriptional regulator ArgP compare
BWI76_RS25060 -1.0 -2.2 lipoprotein NlpI compare
BWI76_RS16360 -1.0 -1.5 electron transport complex subunit RsxB compare
BWI76_RS03610 -1.0 -3.2 hypothetical protein compare
BWI76_RS02410 -1.0 -1.2 EF-P beta-lysylation protein EpmB compare
BWI76_RS13135 -1.0 -2.3 3-oxoadipyl-CoA thiolase compare
BWI76_RS16955 -1.0 -1.2 hypothetical protein compare
BWI76_RS24075 -1.0 -3.2 glutathione synthase compare
BWI76_RS19055 -1.0 -5.9 dTDP-4-dehydrorhamnose 3,5-epimerase compare
BWI76_RS13445 -0.9 -1.5 alpha/beta hydrolase compare
BWI76_RS26775 -0.9 -3.9 endo-1,4-D-glucanase compare
BWI76_RS17980 -0.9 -2.7 RNA chaperone ProQ compare
BWI76_RS06805 -0.9 -0.9 primosomal replication protein N'' compare
BWI76_RS07640 -0.9 -1.2 short chain dehydrogenase compare
BWI76_RS13435 -0.9 -1.5 hypothetical protein compare
BWI76_RS00240 -0.9 -2.8 FMN-binding protein MioC compare
BWI76_RS12460 -0.9 -1.1 envelope stress response membrane protein PspC compare
BWI76_RS16965 -0.9 -2.0 murein lipoprotein compare
BWI76_RS04510 -0.9 -1.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS17805 -0.9 -1.3 membrane protein compare
BWI76_RS15260 -0.9 -1.7 hypothetical protein compare
BWI76_RS14065 -0.9 -1.6 hypothetical protein compare
BWI76_RS18755 -0.8 -1.2 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS25870 -0.8 -1.7 elongation factor Tu compare
BWI76_RS17180 -0.8 -1.8 hypothetical protein compare
BWI76_RS21070 -0.8 -1.7 outer membrane protein assembly factor BamB compare
BWI76_RS25225 -0.8 -4.1 ABC transporter permease compare
BWI76_RS25335 -0.8 -1.6 stringent starvation protein A compare
BWI76_RS04955 -0.8 -1.8 hypoxanthine phosphoribosyltransferase compare
BWI76_RS19215 -0.8 -1.7 proline-specific peptidase compare
BWI76_RS00390 -0.8 -4.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS20440 -0.8 -2.4 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS19685 -0.8 -3.9 lysine transporter compare
BWI76_RS02680 -0.8 -1.0 EamA family transporter compare
BWI76_RS21580 -0.8 -1.5 SsrA-binding protein compare
BWI76_RS22450 -0.8 -2.4 selenoprotein W-related protein compare
BWI76_RS22700 -0.8 -3.5 sulfate adenylyltransferase subunit 2 compare
BWI76_RS20795 -0.8 -1.1 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS04270 -0.8 -3.5 transaldolase compare
BWI76_RS10835 -0.8 -1.2 hypothetical protein compare
BWI76_RS11440 -0.8 -1.1 hypothetical protein compare
BWI76_RS21130 -0.8 -1.8 Fe-S assembly protein IscX compare
BWI76_RS12270 -0.8 -2.6 hypothetical protein compare
BWI76_RS01795 -0.8 -2.9 hypothetical protein compare
BWI76_RS05655 -0.8 -1.9 hypothetical protein compare
BWI76_RS24485 -0.8 -1.7 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS09650 -0.7 -3.4 hypothetical protein compare
BWI76_RS03040 -0.7 -2.9 leucyl aminopeptidase compare


Specific Phenotypes

For 1 genes in this experiment

For stress 2,2'-Dipyridyl in Klebsiella michiganensis M5al

For stress 2,2'-Dipyridyl across organisms