Experiment set12IT008 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_glucose with 2,2'-Dipyridyl 100 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS23920 -6.1 -7.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04160 -5.8 -8.0 phosphoserine phosphatase compare
BWI76_RS20895 -5.7 -5.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04465 -5.6 -7.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS26085 -5.3 -3.7 3-dehydroquinate synthase compare
BWI76_RS20355 -5.0 -5.2 colicin V production protein compare
BWI76_RS23265 -5.0 -4.6 hypothetical protein compare
BWI76_RS04470 -5.0 -13.8 carbamoyl phosphate synthase large subunit compare
BWI76_RS00400 -4.9 -3.4 glutamine synthetase compare
BWI76_RS11965 -4.9 -4.4 orotidine-5'-phosphate decarboxylase compare
BWI76_RS21265 -4.9 -15.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS20965 -4.9 -7.2 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00965 -4.9 -2.2 acetolactate synthase 2 small subunit compare
BWI76_RS27385 -4.8 -8.0 orotate phosphoribosyltransferase compare
BWI76_RS18950 -4.6 -5.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS09755 -4.5 -9.4 phosphoserine transaminase compare
BWI76_RS20350 -4.2 -7.6 amidophosphoribosyltransferase compare
BWI76_RS01615 -4.2 -14.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS07070 -4.1 -5.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS23360 -4.1 -5.3 diaminopimelate decarboxylase compare
BWI76_RS02995 -4.0 -9.0 aspartate carbamoyltransferase compare
BWI76_RS25115 -4.0 -9.9 argininosuccinate synthase compare
BWI76_RS04645 -3.9 -6.0 3-dehydroquinase compare
BWI76_RS09910 -3.8 -16.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS23230 -3.8 -2.6 exodeoxyribonuclease V subunit beta compare
BWI76_RS05835 -3.7 -4.7 gamma-glutamyl-phosphate reductase compare
BWI76_RS09760 -3.7 -5.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS08385 -3.6 -5.0 citrate (Si)-synthase compare
BWI76_RS10990 -3.6 -3.2 dihydroorotase compare
BWI76_RS21475 -3.6 -7.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS23365 -3.5 -9.2 LysR family transcriptional regulator compare
BWI76_RS00990 -3.4 -11.9 ketol-acid reductoisomerase compare
BWI76_RS22690 -3.4 -3.3 adenylyl-sulfate kinase compare
BWI76_RS04255 -3.4 -8.3 threonine synthase compare
BWI76_RS22755 -3.3 -8.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS01610 -3.3 -7.3 phosphoribosylamine--glycine ligase compare
BWI76_RS05840 -3.3 -7.8 glutamate 5-kinase compare
BWI76_RS23220 -3.3 -7.9 amino-acid N-acetyltransferase compare
BWI76_RS07065 -3.3 -8.9 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS00855 -3.3 -10.9 argininosuccinate lyase compare
BWI76_RS08530 -3.2 -3.6 protein TolA compare
BWI76_RS08520 -3.2 -3.2 colicin transporter TolQ compare
BWI76_RS05200 -3.2 -3.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS22765 -3.2 -10.1 sulfite reductase subunit alpha compare
BWI76_RS27390 -3.1 -4.8 ribonuclease PH compare
BWI76_RS00845 -3.1 -11.1 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00785 -3.1 -6.8 cystathionine gamma-synthase compare
BWI76_RS00975 -3.0 -8.2 dihydroxy-acid dehydratase compare
BWI76_RS09645 -3.0 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS09660 -3.0 -2.0 DNA translocase FtsK compare
BWI76_RS04240 -3.0 -4.6 thr operon leader peptide compare
BWI76_RS03010 -2.9 -8.6 ornithine carbamoyltransferase compare
BWI76_RS04250 -2.9 -9.2 homoserine kinase compare
BWI76_RS00835 -2.9 -13.9 phosphoenolpyruvate carboxylase compare
BWI76_RS25645 -2.9 -6.8 shikimate dehydrogenase compare
BWI76_RS20435 -2.8 -2.5 chorismate synthase compare
BWI76_RS18940 -2.8 -6.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS04245 -2.8 -11.5 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS17720 -2.8 -1.8 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS18930 -2.7 -6.5 histidinol-phosphate transaminase compare
BWI76_RS00805 -2.7 -4.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS00850 -2.7 -7.2 acetylglutamate kinase compare
BWI76_RS25335 -2.7 -3.9 stringent starvation protein A compare
BWI76_RS00980 -2.7 -13.7 PLP-dependent threonine dehydratase compare
BWI76_RS18935 -2.6 -6.9 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23240 -2.6 -4.3 exonuclease V subunit gamma compare
BWI76_RS18955 -2.5 -7.4 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS02735 -2.5 -5.0 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS05015 -2.4 -2.8 transcriptional regulator compare
BWI76_RS22805 -2.3 -10.0 GTP diphosphokinase compare
BWI76_RS01655 -2.3 -9.2 homoserine O-succinyltransferase compare
BWI76_RS18925 -2.3 -6.6 histidinol dehydrogenase compare
BWI76_RS22760 -2.3 -6.9 sulfite reductase subunit beta compare
BWI76_RS17975 -2.1 -5.3 tail-specific protease compare
BWI76_RS26000 -2.1 -8.7 aspartate aminotransferase family protein compare
BWI76_RS01200 -2.1 -2.1 diaminopimelate epimerase compare
BWI76_RS04680 -2.1 -9.8 2-isopropylmalate synthase compare
BWI76_RS04665 -2.1 -14.6 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04685 -2.1 -8.6 putative leucine operon leader peptide compare
BWI76_RS24285 -2.1 -9.0 cystathionine beta-lyase compare
BWI76_RS04670 -2.1 -7.6 3-isopropylmalate dehydratase large subunit compare
BWI76_RS26460 -2.0 -5.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS08525 -1.9 -3.7 colicin transporter compare
BWI76_RS20900 -1.8 -2.2 outer membrane protein assembly factor BamC compare
BWI76_RS20650 -1.8 -2.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS19870 -1.8 -3.9 malate:quinone oxidoreductase compare
BWI76_RS04675 -1.8 -5.8 3-isopropylmalate dehydrogenase compare
BWI76_RS25870 -1.8 -2.6 elongation factor Tu compare
BWI76_RS18920 -1.7 -4.3 ATP phosphoribosyltransferase compare
BWI76_RS25320 -1.7 -7.1 glutamate synthase compare
BWI76_RS21465 -1.7 -4.3 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS02530 -1.7 -2.3 tRNA dimethylallyltransferase compare
BWI76_RS00140 -1.7 -1.5 phosphate transport system regulator PhoU compare
BWI76_RS11850 -1.6 -7.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11845 -1.5 -4.9 tryptophan synthase subunit beta compare
BWI76_RS00390 -1.5 -4.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS26570 -1.5 -2.9 anion permease compare
BWI76_RS26470 -1.5 -6.0 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS09655 -1.5 -4.6 leucine-responsive regulatory protein compare
BWI76_RS04530 -1.5 -2.2 peptidylprolyl isomerase SurA compare
BWI76_RS01800 -1.5 -3.8 glucose-6-phosphate isomerase compare
BWI76_RS04715 -1.5 -2.4 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS25315 -1.5 -9.4 glutamate synthase large subunit compare
BWI76_RS11840 -1.4 -4.6 tryptophan synthase subunit alpha compare
BWI76_RS00345 -1.4 -3.1 protein disulfide oxidoreductase DsbA compare
BWI76_RS01210 -1.4 -1.4 tyrosine recombinase XerC compare
BWI76_RS16275 -1.3 -2.2 fumarate hydratase FumA compare
BWI76_RS25600 -1.3 -1.4 tRNA-Thr compare
BWI76_RS19845 -1.3 -4.2 phosphatase compare
BWI76_RS15435 -1.3 -1.8 hypothetical protein compare
BWI76_RS20995 -1.3 -4.6 RNA degradosome polyphosphate kinase compare
BWI76_RS06765 -1.3 -2.9 transcriptional regulator compare
BWI76_RS00180 -1.3 -2.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS20970 -1.3 -2.0 phosphoribosylglycinamide formyltransferase compare
BWI76_RS11860 -1.3 -6.3 anthranilate synthase component I compare
BWI76_RS27430 -1.3 -1.8 (p)ppGpp synthetase compare
BWI76_RS26395 -1.3 -2.6 cell division protein FtsE compare
BWI76_RS15835 -1.2 -1.4 hypothetical protein compare
BWI76_RS00385 -1.2 -6.6 nitrogen assimilation regulatory protein compare
BWI76_RS26055 -1.2 -6.0 siroheme synthase compare
BWI76_RS07725 -1.2 -1.6 iron-enterobactin transporter permease compare
BWI76_RS19840 -1.2 -1.6 hypothetical protein compare
BWI76_RS11335 -1.2 -1.5 tautomerase compare
BWI76_RS06905 -1.2 -5.6 Cu+ exporting ATPase compare
BWI76_RS17665 -1.1 -3.2 proteasome-type protease compare
BWI76_RS00985 -1.1 -4.6 transcriptional regulator IlvY compare
BWI76_RS08210 -1.1 -2.6 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS26455 -1.1 -3.7 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS00960 -1.1 -5.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS26390 -1.1 -2.7 cell division protein FtsX compare
BWI76_RS17980 -1.1 -2.7 RNA chaperone ProQ compare
BWI76_RS12790 -1.1 -1.5 lactate dehydrogenase compare
BWI76_RS21370 -1.1 -1.2 ATP-dependent RNA helicase SrmB compare
BWI76_RS01935 -1.1 -2.7 thiamin phosphate synthase compare
BWI76_RS11520 -1.1 -1.3 hypothetical protein compare
BWI76_RS27235 -1.0 -6.1 murein hydrolase activator EnvC compare
BWI76_RS20440 -1.0 -1.0 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS23480 -1.0 -6.2 EAL domain-containing protein compare
BWI76_RS01630 -1.0 -1.2 16S ribosomal RNA compare
BWI76_RS18065 -1.0 -2.0 DNA polymerase III subunit theta compare
BWI76_RS05260 -1.0 -2.0 chaperone compare
BWI76_RS11855 -1.0 -4.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04510 -1.0 -1.9 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS16965 -1.0 -1.6 murein lipoprotein compare
BWI76_RS10035 -1.0 -1.3 hypothetical protein compare
BWI76_RS24270 -1.0 -2.1 membrane protein compare
BWI76_RS27440 -1.0 -3.3 DNA helicase RecG compare
BWI76_RS05235 -1.0 -1.2 hypothetical protein compare
BWI76_RS17190 -1.0 -2.3 TonB system transport protein TonB compare
BWI76_RS07380 -1.0 -2.1 hypothetical protein compare
BWI76_RS21580 -1.0 -2.0 SsrA-binding protein compare
BWI76_RS14415 -1.0 -2.1 transcriptional regulator, TetR family protein compare
BWI76_RS13645 -1.0 -2.9 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS24100 -1.0 -3.4 YggS family pyridoxal phosphate enzyme compare
BWI76_RS08535 -1.0 -1.1 translocation protein TolB compare
BWI76_RS25925 -0.9 -3.6 hypothetical protein compare
BWI76_RS13445 -0.9 -1.5 alpha/beta hydrolase compare
BWI76_RS11820 -0.9 -1.3 short-chain dehydrogenase/reductase SDR compare
BWI76_RS20155 -0.9 -1.4 NADH-quinone oxidoreductase subunit I compare
BWI76_RS26890 -0.9 -1.5 hypothetical protein compare
BWI76_RS14410 -0.9 -2.4 hypothetical protein compare
BWI76_RS15920 -0.9 -1.5 hypothetical protein compare
BWI76_RS23930 -0.9 -2.9 transcriptional regulator ArgP compare
BWI76_RS09530 -0.9 -1.2 hypothetical protein compare
BWI76_RS17565 -0.9 -1.9 hypothetical protein compare
BWI76_RS23020 -0.9 -2.2 cobalamin biosynthesis protein CbiQ compare
BWI76_RS02180 -0.9 -0.9 hypothetical protein compare
BWI76_RS25505 -0.9 -4.0 RNase E specificity factor CsrD compare
BWI76_RS16210 -0.9 -1.5 hypothetical protein compare
BWI76_RS22695 -0.9 -3.4 sulfate adenylyltransferase compare
BWI76_RS21565 -0.8 -1.0 outer membrane protein assembly factor BamE compare
BWI76_RS19685 -0.8 -2.8 lysine transporter compare
BWI76_RS21690 -0.8 -1.8 hypothetical protein compare
BWI76_RS02410 -0.8 -1.1 EF-P beta-lysylation protein EpmB compare
BWI76_RS25065 -0.8 -2.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS04570 -0.8 -4.0 RNA polymerase-associated protein RapA compare
BWI76_RS21480 -0.8 -3.5 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS09650 -0.8 -3.2 hypothetical protein compare
BWI76_RS14970 -0.8 -1.6 pyrroline-5-carboxylate reductase compare
BWI76_RS25945 -0.8 -2.3 ABC transporter ATP-binding protein compare
BWI76_RS26200 -0.8 -3.7 starch synthase compare
BWI76_RS01385 -0.8 -1.5 potassium transporter compare
BWI76_RS17945 -0.8 -1.5 hypothetical protein compare
BWI76_RS03105 -0.8 -1.0 myo-inosose-2 dehydratase compare
BWI76_RS11300 -0.8 -1.0 cupin compare
BWI76_RS08665 -0.8 -3.7 6-phosphogluconolactonase compare
BWI76_RS25160 -0.8 -1.6 transcription elongation factor GreA compare
BWI76_RS19615 -0.8 -2.6 vancomycin high temperature exclusion protein compare
BWI76_RS11130 -0.8 -4.0 PTS glucose transporter subunit IIBC compare
BWI76_RS11675 -0.8 -2.3 arginine N-succinyltransferase compare
BWI76_RS12785 -0.8 -1.8 heat-shock protein HslJ compare
BWI76_RS16360 -0.7 -1.2 electron transport complex subunit RsxB compare
BWI76_RS26775 -0.7 -3.6 endo-1,4-D-glucanase compare
BWI76_RS23885 -0.7 -1.5 2-octaprenylphenol hydroxylase compare
BWI76_RS06635 -0.7 -2.4 methylated-DNA--protein-cysteine methyltransferase compare
BWI76_RS06335 -0.7 -1.8 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS01070 -0.7 -2.6 thiol reductase thioredoxin compare
BWI76_RS24885 -0.7 -1.2 PTS galactitol transporter subunit IIB compare
BWI76_RS20380 -0.7 -1.1 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS24110 -0.7 -1.8 YggU family protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress 2,2'-Dipyridyl in Klebsiella michiganensis M5al

For stress 2,2'-Dipyridyl across organisms