Experiment set12IT007 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_glucose with 2,2'-Dipyridyl 50 uM

200 most important genes:

  gene name fitness t score description  
BWI76_RS04465 -6.1 -7.3 carbamoyl-phosphate synthase small subunit compare
BWI76_RS23920 -5.6 -8.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS26085 -5.4 -3.7 3-dehydroquinate synthase compare
BWI76_RS11965 -5.3 -4.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS00400 -5.0 -3.4 glutamine synthetase compare
BWI76_RS27385 -4.8 -6.9 orotate phosphoribosyltransferase compare
BWI76_RS09755 -4.7 -11.0 phosphoserine transaminase compare
BWI76_RS20965 -4.6 -7.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS04160 -4.6 -6.4 phosphoserine phosphatase compare
BWI76_RS02995 -4.5 -9.3 aspartate carbamoyltransferase compare
BWI76_RS08520 -4.5 -3.3 colicin transporter TolQ compare
BWI76_RS17720 -4.5 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS04470 -4.4 -12.2 carbamoyl phosphate synthase large subunit compare
BWI76_RS23360 -4.4 -4.6 diaminopimelate decarboxylase compare
BWI76_RS20350 -4.3 -7.4 amidophosphoribosyltransferase compare
BWI76_RS01615 -4.3 -12.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS07070 -4.2 -7.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS10990 -4.1 -5.6 dihydroorotase compare
BWI76_RS20895 -4.0 -5.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS22755 -4.0 -11.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23240 -3.9 -3.8 exonuclease V subunit gamma compare
BWI76_RS08525 -3.8 -4.5 colicin transporter compare
BWI76_RS21265 -3.7 -11.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS09910 -3.7 -18.2 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS20435 -3.7 -2.2 chorismate synthase compare
BWI76_RS22690 -3.7 -4.3 adenylyl-sulfate kinase compare
BWI76_RS23265 -3.7 -3.3 hypothetical protein compare
BWI76_RS20355 -3.7 -7.0 colicin V production protein compare
BWI76_RS01610 -3.5 -7.4 phosphoribosylamine--glycine ligase compare
BWI76_RS20650 -3.5 -3.4 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS26570 -3.5 -5.3 anion permease compare
BWI76_RS04645 -3.5 -8.3 3-dehydroquinase compare
BWI76_RS08385 -3.5 -4.2 citrate (Si)-synthase compare
BWI76_RS07065 -3.4 -9.4 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS05200 -3.3 -4.5 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS18950 -3.3 -6.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS08530 -3.2 -1.8 protein TolA compare
BWI76_RS00975 -3.2 -11.4 dihydroxy-acid dehydratase compare
BWI76_RS04255 -3.2 -8.1 threonine synthase compare
BWI76_RS00850 -3.2 -13.1 acetylglutamate kinase compare
BWI76_RS18930 -3.1 -8.5 histidinol-phosphate transaminase compare
BWI76_RS09645 -3.1 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS23365 -3.0 -7.1 LysR family transcriptional regulator compare
BWI76_RS09660 -3.0 -2.1 DNA translocase FtsK compare
BWI76_RS18935 -3.0 -7.1 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS09760 -3.0 -3.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS18955 -2.9 -6.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS18925 -2.9 -5.4 histidinol dehydrogenase compare
BWI76_RS22765 -2.9 -10.8 sulfite reductase subunit alpha compare
BWI76_RS05015 -2.9 -3.5 transcriptional regulator compare
BWI76_RS00855 -2.9 -11.7 argininosuccinate lyase compare
BWI76_RS18920 -2.9 -2.8 ATP phosphoribosyltransferase compare
BWI76_RS21475 -2.9 -5.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS02530 -2.8 -3.3 tRNA dimethylallyltransferase compare
BWI76_RS23230 -2.8 -4.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS22760 -2.8 -7.0 sulfite reductase subunit beta compare
BWI76_RS00990 -2.8 -9.3 ketol-acid reductoisomerase compare
BWI76_RS00845 -2.7 -10.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS05840 -2.7 -4.6 glutamate 5-kinase compare
BWI76_RS25115 -2.7 -7.8 argininosuccinate synthase compare
BWI76_RS03010 -2.6 -8.1 ornithine carbamoyltransferase compare
BWI76_RS00835 -2.6 -12.5 phosphoenolpyruvate carboxylase compare
BWI76_RS04245 -2.6 -11.9 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS26460 -2.6 -5.6 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS05835 -2.6 -3.1 gamma-glutamyl-phosphate reductase compare
BWI76_RS23220 -2.6 -7.7 amino-acid N-acetyltransferase compare
BWI76_RS00965 -2.5 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS02735 -2.5 -5.3 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS00980 -2.4 -12.0 PLP-dependent threonine dehydratase compare
BWI76_RS26395 -2.4 -4.8 cell division protein FtsE compare
BWI76_RS04250 -2.4 -7.0 homoserine kinase compare
BWI76_RS04715 -2.4 -2.9 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS18940 -2.4 -4.6 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS01210 -2.4 -2.8 tyrosine recombinase XerC compare
BWI76_RS26390 -2.3 -6.3 cell division protein FtsX compare
BWI76_RS21580 -2.2 -3.0 SsrA-binding protein compare
BWI76_RS04240 -2.2 -4.1 thr operon leader peptide compare
BWI76_RS22805 -2.2 -9.7 GTP diphosphokinase compare
BWI76_RS21465 -2.2 -5.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS20380 -2.1 -2.1 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS04670 -2.1 -11.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS23480 -2.0 -10.6 EAL domain-containing protein compare
BWI76_RS08535 -2.0 -1.7 translocation protein TolB compare
BWI76_RS04665 -2.0 -13.6 3-isopropylmalate dehydratase small subunit compare
BWI76_RS27390 -1.9 -3.4 ribonuclease PH compare
BWI76_RS04530 -1.9 -2.6 peptidylprolyl isomerase SurA compare
BWI76_RS04685 -1.9 -9.3 putative leucine operon leader peptide compare
BWI76_RS04680 -1.9 -10.5 2-isopropylmalate synthase compare
BWI76_RS01185 -1.9 -3.1 adenylate cyclase compare
BWI76_RS21070 -1.9 -3.2 outer membrane protein assembly factor BamB compare
BWI76_RS11845 -1.8 -5.7 tryptophan synthase subunit beta compare
BWI76_RS00785 -1.8 -7.1 cystathionine gamma-synthase compare
BWI76_RS00805 -1.8 -3.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS00390 -1.8 -6.2 two-component system sensor histidine kinase NtrB compare
BWI76_RS01655 -1.8 -6.2 homoserine O-succinyltransferase compare
BWI76_RS11860 -1.8 -7.0 anthranilate synthase component I compare
BWI76_RS04675 -1.8 -6.7 3-isopropylmalate dehydrogenase compare
BWI76_RS20360 -1.8 -1.5 cell division protein DedD compare
BWI76_RS17975 -1.7 -5.0 tail-specific protease compare
BWI76_RS26470 -1.7 -4.6 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS00385 -1.7 -10.2 nitrogen assimilation regulatory protein compare
BWI76_RS25335 -1.7 -4.0 stringent starvation protein A compare
BWI76_RS24285 -1.7 -7.0 cystathionine beta-lyase compare
BWI76_RS25320 -1.6 -5.7 glutamate synthase compare
BWI76_RS21565 -1.6 -1.6 outer membrane protein assembly factor BamE compare
BWI76_RS26000 -1.6 -6.8 aspartate aminotransferase family protein compare
BWI76_RS26455 -1.6 -4.5 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS27430 -1.6 -1.7 (p)ppGpp synthetase compare
BWI76_RS25645 -1.6 -6.7 shikimate dehydrogenase compare
BWI76_RS20995 -1.6 -3.5 RNA degradosome polyphosphate kinase compare
BWI76_RS00180 -1.5 -2.6 F0F1 ATP synthase subunit epsilon compare
BWI76_RS11635 -1.5 -2.4 ABC transporter compare
BWI76_RS00760 -1.5 -3.6 cell division protein FtsN compare
BWI76_RS25315 -1.5 -9.8 glutamate synthase large subunit compare
BWI76_RS19845 -1.4 -4.4 phosphatase compare
BWI76_RS06765 -1.4 -2.6 transcriptional regulator compare
BWI76_RS11850 -1.4 -6.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11840 -1.4 -3.1 tryptophan synthase subunit alpha compare
BWI76_RS09970 -1.4 -1.9 porin OmpA compare
BWI76_RS27235 -1.3 -8.1 murein hydrolase activator EnvC compare
BWI76_RS01200 -1.3 -1.3 diaminopimelate epimerase compare
BWI76_RS21480 -1.3 -4.0 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS00345 -1.3 -1.7 protein disulfide oxidoreductase DsbA compare
BWI76_RS11855 -1.2 -4.8 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS01800 -1.2 -4.3 glucose-6-phosphate isomerase compare
BWI76_RS19870 -1.2 -2.1 malate:quinone oxidoreductase compare
BWI76_RS26055 -1.2 -5.1 siroheme synthase compare
BWI76_RS00355 -1.2 -3.2 DNA polymerase I compare
BWI76_RS07985 -1.2 -1.2 fluoride ion transporter CrcB compare
BWI76_RS04510 -1.2 -2.3 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS06770 -1.2 -7.6 Hha toxicity attenuator compare
BWI76_RS25070 -1.2 -1.8 hypothetical protein compare
BWI76_RS27440 -1.1 -3.4 DNA helicase RecG compare
BWI76_RS17980 -1.1 -3.9 RNA chaperone ProQ compare
BWI76_RS25485 -1.1 -1.8 septum formation protein Maf compare
BWI76_RS13820 -1.1 -2.2 hypothetical protein compare
BWI76_RS18065 -1.1 -2.2 DNA polymerase III subunit theta compare
BWI76_RS01795 -1.1 -3.1 hypothetical protein compare
BWI76_RS11440 -1.1 -1.4 hypothetical protein compare
BWI76_RS25425 -1.1 -1.2 arginine repressor compare
BWI76_RS04305 -1.0 -1.1 molecular chaperone DnaJ compare
BWI76_RS14320 -1.0 -2.5 hypothetical protein compare
BWI76_RS01325 -1.0 -2.3 twin-arginine translocase subunit TatB compare
BWI76_RS24885 -1.0 -0.9 PTS galactitol transporter subunit IIB compare
BWI76_RS05260 -1.0 -2.1 chaperone compare
BWI76_RS08210 -1.0 -2.5 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS18710 -1.0 -7.4 GGDEF-domain containing protein compare
BWI76_RS17675 -1.0 -1.6 hypothetical protein compare
BWI76_RS24955 -0.9 -2.0 hypothetical protein compare
BWI76_RS16375 -0.9 -2.2 electron transport complex subunit G compare
BWI76_RS12895 -0.9 -2.2 hypothetical protein compare
BWI76_RS07185 -0.9 -1.1 hypothetical protein compare
BWI76_RS24120 -0.9 -3.8 YggW family oxidoreductase compare
BWI76_RS15290 -0.9 -1.4 transcriptional regulator compare
BWI76_RS18165 -0.9 -1.3 NUDIX pyrophosphatase compare
BWI76_RS17370 -0.9 -1.6 nitrate transporter NasD compare
BWI76_RS25870 -0.9 -1.7 elongation factor Tu compare
BWI76_RS09650 -0.9 -3.1 hypothetical protein compare
BWI76_RS12345 -0.9 -1.7 nitrite transporter compare
BWI76_RS21370 -0.9 -1.5 ATP-dependent RNA helicase SrmB compare
BWI76_RS13645 -0.9 -2.0 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS13560 -0.9 -1.1 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS14390 -0.9 -1.9 hypothetical protein compare
BWI76_RS15215 -0.9 -1.1 N-acetyltransferase compare
BWI76_RS04570 -0.9 -3.8 RNA polymerase-associated protein RapA compare
BWI76_RS23485 -0.9 -3.9 hypothetical protein compare
BWI76_RS20440 -0.8 -0.9 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS20640 -0.8 -3.9 cysteine synthase A compare
BWI76_RS09655 -0.8 -2.3 leucine-responsive regulatory protein compare
BWI76_RS25505 -0.8 -3.8 RNase E specificity factor CsrD compare
BWI76_RS00985 -0.8 -3.6 transcriptional regulator IlvY compare
BWI76_RS09895 -0.8 -2.9 aliphatic sulfonates ABC transporter ATP-binding protein compare
BWI76_RS08665 -0.8 -4.7 6-phosphogluconolactonase compare
BWI76_RS25280 -0.8 -1.7 RNase adaptor protein RapZ compare
BWI76_RS12495 -0.8 -1.6 2-Cys peroxiredoxin compare
BWI76_RS16805 -0.8 -1.7 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS18385 -0.8 -1.3 hypothetical protein compare
BWI76_RS00960 -0.8 -4.2 acetolactate synthase 2 catalytic subunit compare
BWI76_RS06905 -0.8 -4.0 Cu+ exporting ATPase compare
BWI76_RS06530 -0.8 -2.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS25285 -0.8 -0.9 HPr family phosphocarrier protein compare
BWI76_RS16470 -0.8 -1.4 transcriptional repressor NemR compare
BWI76_RS05450 -0.8 -1.3 ribonuclease HI compare
BWI76_RS07820 -0.8 -1.9 S-methyl-5-thioribose kinase compare
BWI76_RS25065 -0.8 -1.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS06560 -0.7 -2.5 7-cyano-7-deazaguanine synthase QueC compare
BWI76_RS18715 -0.7 -4.0 hypothetical protein compare
BWI76_RS17190 -0.7 -1.2 TonB system transport protein TonB compare
BWI76_RS24575 -0.7 -1.0 hypothetical protein compare
BWI76_RS19840 -0.7 -1.2 hypothetical protein compare
BWI76_RS19685 -0.7 -3.4 lysine transporter compare
BWI76_RS01220 -0.7 -3.4 DNA-dependent helicase II compare
BWI76_RS09710 -0.7 -2.2 transketolase compare
BWI76_RS06525 -0.7 -3.8 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS12550 -0.7 -2.0 hypothetical protein compare
BWI76_RS16485 -0.7 -1.5 ribonuclease T compare
BWI76_RS23885 -0.7 -1.5 2-octaprenylphenol hydroxylase compare
BWI76_RS15605 -0.7 -1.1 hypothetical protein compare
BWI76_RS20900 -0.7 -0.9 outer membrane protein assembly factor BamC compare
BWI76_RS18415 -0.7 -2.3 very short patch repair endonuclease compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in stress experiments

For stress 2,2'-Dipyridyl across organisms