Experiment set12IT002 for Klebsiella michiganensis M5al

Compare to:

D-Glucose 80 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -8.9 -6.1 colicin V production protein compare
BWI76_RS23920 -6.0 -8.2 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04465 -5.8 -6.9 carbamoyl-phosphate synthase small subunit compare
BWI76_RS26085 -5.5 -3.8 3-dehydroquinate synthase compare
BWI76_RS20350 -5.4 -7.2 amidophosphoribosyltransferase compare
BWI76_RS20965 -5.4 -6.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00400 -5.1 -3.5 glutamine synthetase compare
BWI76_RS04470 -5.0 -9.8 carbamoyl phosphate synthase large subunit compare
BWI76_RS09755 -4.8 -10.1 phosphoserine transaminase compare
BWI76_RS07065 -4.6 -10.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS07070 -4.5 -5.4 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS01615 -4.5 -13.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS27385 -4.5 -10.8 orotate phosphoribosyltransferase compare
BWI76_RS21265 -4.4 -15.5 phosphoribosylformylglycinamidine synthase compare
BWI76_RS23240 -4.4 -3.0 exonuclease V subunit gamma compare
BWI76_RS23360 -4.3 -5.8 diaminopimelate decarboxylase compare
BWI76_RS02995 -4.3 -7.8 aspartate carbamoyltransferase compare
BWI76_RS04160 -4.2 -10.4 phosphoserine phosphatase compare
BWI76_RS01610 -4.2 -8.0 phosphoribosylamine--glycine ligase compare
BWI76_RS20895 -4.1 -7.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS09910 -4.1 -16.7 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS18950 -3.7 -6.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS22755 -3.5 -11.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11965 -3.5 -6.1 orotidine-5'-phosphate decarboxylase compare
BWI76_RS00855 -3.5 -10.2 argininosuccinate lyase compare
BWI76_RS04250 -3.5 -7.9 homoserine kinase compare
BWI76_RS18920 -3.4 -3.8 ATP phosphoribosyltransferase compare
BWI76_RS04255 -3.4 -11.9 threonine synthase compare
BWI76_RS04645 -3.4 -9.7 3-dehydroquinase compare
BWI76_RS18935 -3.3 -11.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00990 -3.2 -10.3 ketol-acid reductoisomerase compare
BWI76_RS18925 -3.2 -10.0 histidinol dehydrogenase compare
BWI76_RS22760 -3.2 -9.6 sulfite reductase subunit beta compare
BWI76_RS09660 -3.1 -2.1 DNA translocase FtsK compare
BWI76_RS05015 -3.1 -5.1 transcriptional regulator compare
BWI76_RS23220 -3.1 -11.3 amino-acid N-acetyltransferase compare
BWI76_RS18930 -3.1 -8.5 histidinol-phosphate transaminase compare
BWI76_RS00850 -3.0 -13.2 acetylglutamate kinase compare
BWI76_RS00835 -3.0 -14.0 phosphoenolpyruvate carboxylase compare
BWI76_RS23230 -3.0 -4.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS05835 -2.9 -4.0 gamma-glutamyl-phosphate reductase compare
BWI76_RS00975 -2.9 -8.1 dihydroxy-acid dehydratase compare
BWI76_RS23365 -2.9 -7.6 LysR family transcriptional regulator compare
BWI76_RS22765 -2.9 -8.6 sulfite reductase subunit alpha compare
BWI76_RS21475 -2.8 -7.1 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS03010 -2.8 -10.2 ornithine carbamoyltransferase compare
BWI76_RS02530 -2.8 -3.3 tRNA dimethylallyltransferase compare
BWI76_RS00845 -2.8 -7.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS25645 -2.8 -7.9 shikimate dehydrogenase compare
BWI76_RS25115 -2.8 -7.1 argininosuccinate synthase compare
BWI76_RS22690 -2.8 -3.7 adenylyl-sulfate kinase compare
BWI76_RS09760 -2.7 -2.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS10990 -2.7 -4.5 dihydroorotase compare
BWI76_RS04245 -2.7 -14.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS05840 -2.7 -7.2 glutamate 5-kinase compare
BWI76_RS00805 -2.7 -4.9 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS27390 -2.6 -4.2 ribonuclease PH compare
BWI76_RS18940 -2.6 -6.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS01210 -2.6 -2.9 tyrosine recombinase XerC compare
BWI76_RS08385 -2.6 -5.1 citrate (Si)-synthase compare
BWI76_RS18955 -2.5 -5.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS26570 -2.5 -5.3 anion permease compare
BWI76_RS02735 -2.5 -6.2 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS11840 -2.5 -4.1 tryptophan synthase subunit alpha compare
BWI76_RS00980 -2.4 -11.5 PLP-dependent threonine dehydratase compare
BWI76_RS04675 -2.3 -6.5 3-isopropylmalate dehydrogenase compare
BWI76_RS25320 -2.3 -7.7 glutamate synthase compare
BWI76_RS17720 -2.2 -1.6 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS04680 -2.2 -11.6 2-isopropylmalate synthase compare
BWI76_RS25870 -2.2 -2.8 elongation factor Tu compare
BWI76_RS04665 -2.1 -13.9 3-isopropylmalate dehydratase small subunit compare
BWI76_RS27430 -2.1 -2.1 (p)ppGpp synthetase compare
BWI76_RS25315 -2.1 -11.9 glutamate synthase large subunit compare
BWI76_RS22805 -2.1 -10.5 GTP diphosphokinase compare
BWI76_RS20970 -2.1 -2.6 phosphoribosylglycinamide formyltransferase compare
BWI76_RS11845 -2.1 -5.8 tryptophan synthase subunit beta compare
BWI76_RS05200 -2.0 -3.5 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS18770 -2.0 -2.0 DNA gyrase inhibitor compare
BWI76_RS04670 -2.0 -9.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS08525 -1.9 -3.6 colicin transporter compare
BWI76_RS04685 -1.9 -9.3 putative leucine operon leader peptide compare
BWI76_RS09655 -1.9 -5.9 leucine-responsive regulatory protein compare
BWI76_RS20435 -1.9 -2.1 chorismate synthase compare
BWI76_RS00785 -1.9 -7.3 cystathionine gamma-synthase compare
BWI76_RS25425 -1.9 -2.9 arginine repressor compare
BWI76_RS24285 -1.8 -8.4 cystathionine beta-lyase compare
BWI76_RS01655 -1.8 -8.6 homoserine O-succinyltransferase compare
BWI76_RS11860 -1.8 -6.7 anthranilate synthase component I compare
BWI76_RS23885 -1.8 -1.4 2-octaprenylphenol hydroxylase compare
BWI76_RS20650 -1.7 -3.0 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS08520 -1.7 -2.0 colicin transporter TolQ compare
BWI76_RS26000 -1.5 -5.8 aspartate aminotransferase family protein compare
BWI76_RS26390 -1.5 -5.7 cell division protein FtsX compare
BWI76_RS00390 -1.5 -4.2 two-component system sensor histidine kinase NtrB compare
BWI76_RS26055 -1.5 -7.6 siroheme synthase compare
BWI76_RS11850 -1.5 -8.1 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26395 -1.5 -2.5 cell division protein FtsE compare
BWI76_RS21580 -1.4 -2.8 SsrA-binding protein compare
BWI76_RS19840 -1.4 -1.8 hypothetical protein compare
BWI76_RS17975 -1.4 -3.9 tail-specific protease compare
BWI76_RS09645 -1.4 -1.3 thioredoxin-disulfide reductase compare
BWI76_RS04715 -1.4 -2.3 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS21465 -1.4 -4.4 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS23265 -1.3 -3.5 hypothetical protein compare
BWI76_RS04240 -1.3 -2.3 thr operon leader peptide compare
BWI76_RS11855 -1.3 -6.0 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS08535 -1.3 -1.7 translocation protein TolB compare
BWI76_RS22695 -1.3 -3.7 sulfate adenylyltransferase compare
BWI76_RS01800 -1.3 -3.6 glucose-6-phosphate isomerase compare
BWI76_RS02410 -1.3 -1.4 EF-P beta-lysylation protein EpmB compare
BWI76_RS00345 -1.3 -2.7 protein disulfide oxidoreductase DsbA compare
BWI76_RS26075 -1.2 -3.3 DNA adenine methylase compare
BWI76_RS00385 -1.2 -7.7 nitrogen assimilation regulatory protein compare
BWI76_RS12790 -1.2 -1.6 lactate dehydrogenase compare
BWI76_RS05880 -1.2 -1.8 AraC-type DNA-binding domain-containing protein compare
BWI76_RS21480 -1.2 -5.3 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS26620 -1.2 -1.4 Fe-S biogenesis protein NfuA compare
BWI76_RS00960 -1.1 -5.4 acetolactate synthase 2 catalytic subunit compare
BWI76_RS22700 -1.1 -3.6 sulfate adenylyltransferase subunit 2 compare
BWI76_RS00965 -1.1 -1.2 acetolactate synthase 2 small subunit compare
BWI76_RS18755 -1.1 -1.3 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS08530 -1.1 -1.5 protein TolA compare
BWI76_RS25335 -1.1 -1.5 stringent starvation protein A compare
BWI76_RS01275 -1.1 -3.6 LysR family transcriptional regulator compare
BWI76_RS00985 -1.1 -4.0 transcriptional regulator IlvY compare
BWI76_RS00970 -1.1 -3.2 branched chain amino acid aminotransferase compare
BWI76_RS08665 -1.0 -5.4 6-phosphogluconolactonase compare
BWI76_RS15605 -1.0 -2.3 hypothetical protein compare
BWI76_RS21505 -1.0 -1.2 hypothetical protein compare
BWI76_RS15215 -1.0 -1.2 N-acetyltransferase compare
BWI76_RS21690 -1.0 -2.0 hypothetical protein compare
BWI76_RS03665 -1.0 -1.7 ABC transporter ATP-binding protein compare
BWI76_RS00180 -1.0 -1.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS16895 -1.0 -1.9 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS25505 -0.9 -5.8 RNase E specificity factor CsrD compare
BWI76_RS14770 -0.9 -1.4 PTS IIA 2 domain protein compare
BWI76_RS26455 -0.9 -3.2 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS26470 -0.9 -3.2 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS14050 -0.9 -1.9 AP endonuclease, family 2 compare
BWI76_RS01070 -0.9 -3.7 thiol reductase thioredoxin compare
BWI76_RS01200 -0.9 -1.0 diaminopimelate epimerase compare
BWI76_RS20640 -0.9 -2.6 cysteine synthase A compare
BWI76_RS23915 -0.9 -1.9 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS20440 -0.9 -1.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS13685 -0.9 -2.1 IclR family transcriptional regulator compare
BWI76_RS18065 -0.8 -1.8 DNA polymerase III subunit theta compare
BWI76_RS12495 -0.8 -1.6 2-Cys peroxiredoxin compare
BWI76_RS20995 -0.8 -2.3 RNA degradosome polyphosphate kinase compare
BWI76_RS10835 -0.8 -1.3 hypothetical protein compare
BWI76_RS21075 -0.8 -0.9 membrane protein compare
BWI76_RS23970 -0.8 -2.1 mechanosensitive ion channel protein MscS compare
BWI76_RS18390 -0.8 -1.7 hypothetical protein compare
BWI76_RS00720 -0.8 -1.8 DNA-binding response regulator compare
BWI76_RS09650 -0.8 -2.9 hypothetical protein compare
BWI76_RS25285 -0.8 -1.0 HPr family phosphocarrier protein compare
BWI76_RS00240 -0.8 -2.0 FMN-binding protein MioC compare
BWI76_RS20750 -0.8 -1.1 carboxysome structural protein EutK compare
BWI76_RS14915 -0.8 -1.9 hypothetical protein compare
BWI76_RS26890 -0.8 -1.3 hypothetical protein compare
BWI76_RS04305 -0.8 -0.9 molecular chaperone DnaJ compare
BWI76_RS21310 -0.8 -0.9 DNA repair protein RecO compare
BWI76_RS04530 -0.8 -1.0 peptidylprolyl isomerase SurA compare
BWI76_RS01890 -0.8 -3.8 transcriptional regulator Zur compare
BWI76_RS23480 -0.8 -5.0 EAL domain-containing protein compare
BWI76_RS12345 -0.8 -1.4 nitrite transporter compare
BWI76_RS01385 -0.8 -1.7 potassium transporter compare
BWI76_RS05235 -0.8 -1.0 hypothetical protein compare
BWI76_RS02050 -0.8 -1.5 CidA/LrgA family protein compare
BWI76_RS24080 -0.7 -1.6 DUF179 domain-containing protein compare
BWI76_RS12145 -0.7 -1.1 hypothetical protein compare
BWI76_RS12090 -0.7 -1.6 HNH endonuclease compare
BWI76_RS25065 -0.7 -2.5 polyribonucleotide nucleotidyltransferase compare
BWI76_RS00355 -0.7 -1.6 DNA polymerase I compare
BWI76_RS11130 -0.7 -3.5 PTS glucose transporter subunit IIBC compare
BWI76_RS13135 -0.7 -2.3 3-oxoadipyl-CoA thiolase compare
BWI76_RS06765 -0.7 -2.2 transcriptional regulator compare
BWI76_RS17955 -0.7 -2.2 hypothetical protein compare
BWI76_RS18190 -0.7 -1.2 carboxy-S-adenosyl-L-methionine synthase CmoA compare
BWI76_RS01325 -0.7 -1.3 twin-arginine translocase subunit TatB compare
BWI76_RS12390 -0.7 -1.1 antibiotic biosynthesis monooxygenase compare
BWI76_RS10580 -0.7 -2.2 amino acid ABC transporter permease compare
BWI76_RS21235 -0.7 -1.0 hypothetical protein compare
BWI76_RS27875 -0.7 -0.9 membrane protein compare
BWI76_RS02680 -0.7 -1.3 EamA family transporter compare
BWI76_RS07605 -0.7 -1.7 N-acetyltransferase GCN5 compare
BWI76_RS14835 -0.7 -1.0 hypothetical protein compare
BWI76_RS17180 -0.7 -2.3 hypothetical protein compare
BWI76_RS01685 -0.7 -4.4 methionine synthase compare
BWI76_RS22715 -0.6 -2.5 type I-E CRISPR-associated endoribonuclease Cas2 compare
BWI76_RS23930 -0.6 -3.1 transcriptional regulator ArgP compare
BWI76_RS20050 -0.6 -1.1 hypothetical protein compare
BWI76_RS04510 -0.6 -1.2 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS07820 -0.6 -1.5 S-methyl-5-thioribose kinase compare
BWI76_RS24925 -0.6 -1.2 DnaA initiator-associating protein DiaA compare
BWI76_RS16000 -0.6 -1.0 multidrug transporter subunit MdtI compare
BWI76_RS00140 -0.6 -0.7 phosphate transport system regulator PhoU compare
BWI76_RS04570 -0.6 -2.9 RNA polymerase-associated protein RapA compare
BWI76_RS11430 -0.6 -0.9 lipoprotein compare
BWI76_RS08260 -0.6 -2.2 LysR family transcriptional regulator compare
BWI76_RS11235 -0.6 -0.9 hypothetical protein compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source D-Glucose across organisms