Experiment set12H3 for Pseudomonas stutzeri RCH2

Compare to:

L-Malic acid disodium salt monohydrate carbon source

200 most important genes:

  gene name fitness t score description  
Psest_3944 -7.7 -5.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_3650 -6.4 -14.3 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3648 -6.4 -8.7 anthranilate phosphoribosyltransferase compare
Psest_0508 -6.2 -12.0 gamma-glutamyl phosphate reductase compare
Psest_3721 -6.2 -8.5 Malic enzyme compare
Psest_3866 -6.1 -19.0 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3647 -6.1 -8.4 Indole-3-glycerol phosphate synthase compare
Psest_3384 -6.1 -9.4 glutamate 5-kinase compare
Psest_0062 -6.1 -13.6 tryptophan synthase, alpha subunit compare
Psest_0155 -6.0 -7.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_2584 -5.9 -7.0 Phosphoribosylanthranilate isomerase compare
Psest_3299 -5.9 -17.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0153 -5.9 -14.7 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_2578 -5.6 -16.2 O-succinylhomoserine sulfhydrylase compare
Psest_0152 -5.6 -5.4 Imidazoleglycerol-phosphate dehydratase compare
Psest_3298 -5.4 -14.5 histidinol dehydrogenase compare
Psest_0063 -5.4 -14.0 tryptophan synthase, beta subunit compare
Psest_1473 -5.4 -7.4 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0313 -5.2 -7.1 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_0279 -5.0 -8.4 methionine biosynthesis protein MetW compare
Psest_3864 -5.0 -17.0 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0280 -4.9 -13.7 homoserine O-acetyltransferase compare
Psest_2088 -4.6 -3.6 Uncharacterized protein conserved in bacteria compare
Psest_2589 -4.5 -12.5 3-isopropylmalate dehydrogenase compare
Psest_0325 -4.4 -13.6 Putative threonine efflux protein compare
Psest_2590 -4.4 -2.2 3-isopropylmalate dehydratase, small subunit compare
Psest_3943 -4.4 -6.1 Phosphoribosyl-AMP cyclohydrolase compare
Psest_3998 -4.4 -8.9 glutamate--cysteine ligase compare
Psest_3649 -4.4 -12.8 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0326 -4.4 -13.5 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0687 -4.3 -11.7 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_2591 -4.3 -6.0 3-isopropylmalate dehydratase, large subunit compare
Psest_3818 -4.2 -9.7 endoribonuclease L-PSP, putative compare
Psest_0718 -4.0 -6.5 nicotinate-nucleotide pyrophosphorylase compare
Psest_1686 -3.9 -6.8 fatty acid/phospholipid synthesis protein PlsX compare
Psest_2579 -3.7 -3.6 amidophosphoribosyltransferase compare
Psest_1295 -3.4 -9.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2329 -3.4 -17.8 Transcriptional regulator compare
Psest_3297 -3.1 -13.3 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_2090 -2.9 -5.7 Protein of unknown function (DUF2970). compare
Psest_1772 -2.9 -6.3 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_1037 -2.7 -4.5 acetolactate synthase, small subunit compare
Psest_3351 -2.5 -7.2 peptide chain release factor 3 compare
Psest_1474 -2.4 -1.7 phosphoribosylaminoimidazole synthetase compare
Psest_0327 -2.4 -4.2 Transcriptional regulator compare
Psest_3301 -2.4 -5.9 Predicted transcriptional regulator, BolA superfamily compare
Psest_1509 -2.4 -10.4 quinolinate synthetase complex, A subunit compare
Psest_2651 -2.3 -5.5 DNA topoisomerase I, bacterial compare
Psest_0489 -2.3 -1.6 phosphoserine phosphatase SerB compare
Psest_2862 -2.3 -10.7 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_0498 -2.3 -2.2 ribosome small subunit-dependent GTPase A compare
Psest_2333 -2.3 -1.8 Protein of unknown function (DUF3359). compare
Psest_3226 -2.2 -1.9 Predicted membrane protein compare
Psest_1013 -2.2 -3.2 phosphoribosylamine--glycine ligase compare
Psest_1496 -2.1 -1.4 Holliday junction DNA helicase, RuvA subunit compare
Psest_2532 -2.0 -5.1 Uncharacterized protein conserved in bacteria compare
Psest_1704 -2.0 -1.9 Dehydrogenases (flavoproteins) compare
Psest_3810 -2.0 -1.3 orotate phosphoribosyltransferase compare
Psest_0442 -1.9 -2.6 ATPases of the AAA+ class compare
Psest_4044 -1.9 -2.9 type I site-specific deoxyribonuclease, HsdR family compare
Psest_2944 -1.9 -1.3 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_2327 -1.8 -8.2 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_3843 -1.7 -6.5 4-hydroxybenzoate synthetase (chorismate lyase) compare
Psest_2325 -1.7 -9.7 alpha-L-glutamate ligase-related protein compare
Psest_3922 -1.7 -5.2 Response regulator of citrate/malate metabolism conserved
Psest_2650 -1.6 -3.9 hypothetical protein compare
Psest_3159 -1.6 -6.0 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_3988 -1.6 -7.4 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_2809 -1.6 -3.6 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_2324 -1.6 -12.5 hypothetical protein compare
Psest_0257 -1.6 -3.9 Predicted Zn-dependent peptidases compare
Psest_0284 -1.5 -10.6 pyridoxal phosphate enzyme, YggS family compare
Psest_3338 -1.5 -2.0 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_3860 -1.5 -3.5 Predicted permeases compare
Psest_0028 -1.5 -4.1 Coproporphyrinogen III oxidase compare
Psest_2323 -1.5 -10.8 Uncharacterized protein conserved in archaea compare
Psest_2104 -1.5 -2.1 IscR-regulated protein YhgI compare
Psest_4003 -1.4 -4.7 TIGR00153 family protein compare
Psest_1292 -1.4 -7.8 monothiol glutaredoxin, Grx4 family compare
Psest_1277 -1.4 -8.3 2-isopropylmalate synthase, yeast type compare
Psest_3101 -1.4 -10.4 L-aspartate oxidase compare
Psest_1947 -1.4 -0.9 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_2863 -1.3 -4.7 Transcriptional regulator compare
Psest_3456 -1.3 -2.0 RNA polymerase sigma factor, sigma-70 family compare
Psest_1661 -1.3 -2.3 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_4406 -1.2 -1.4 hypothetical protein compare
Psest_3322 -1.2 -10.5 TIGR02099 family protein compare
Psest_2023 -1.2 -2.5 isocitrate dehydrogenase, NADP-dependent, monomeric type compare
Psest_4191 -1.2 -2.6 Transcriptional regulator compare
Psest_3228 -1.2 -7.4 Zn-dependent protease with chaperone function compare
Psest_0722 -1.2 -6.4 Predicted ATPase compare
Psest_2018 -1.2 -2.7 Uncharacterized conserved protein compare
Psest_3767 -1.2 -2.9 tyrosine recombinase XerC compare
Psest_1012 -1.2 -4.3 Signal transduction histidine kinase compare
Psest_1695 -1.1 -3.5 Tfp pilus assembly protein PilZ compare
Psest_0445 -1.1 -7.8 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3924 -1.1 -8.2 Na+/citrate symporter compare
Psest_0959 -1.1 -2.3 Uncharacterized protein conserved in bacteria compare
Psest_2538 -1.1 -1.8 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases compare
Psest_3720 -1.1 -8.7 penicillin-binding protein, 1A family compare
Psest_2527 -1.1 -5.0 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_2718 -1.1 -1.5 hypothetical protein compare
Psest_0969 -1.0 -2.2 transcription elongation factor GreA compare
Psest_0485 -1.0 -2.1 clan AA aspartic protease, TIGR02281 family compare
Psest_1724 -1.0 -3.0 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_2946 -1.0 -2.6 septum site-determining protein MinD compare
Psest_0138 -1.0 -6.2 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_1643 -1.0 -1.4 hypothetical protein compare
Psest_1655 -1.0 -3.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit compare
Psest_3395 -1.0 -1.2 hypothetical protein compare
Psest_3853 -1.0 -2.1 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_0296 -0.9 -5.6 glutathione synthetase, prokaryotic compare
Psest_3923 -0.9 -5.9 Signal transduction histidine kinase regulating citrate/malate metabolism compare
Psest_1636 -0.9 -4.0 putative transporter, required for glycine utilization (from data) compare
Psest_3042 -0.9 -1.5 Nitrate reductase cytochrome c-type subunit compare
Psest_1656 -0.9 -2.0 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_3458 -0.9 -3.3 hypothetical protein compare
Psest_0193 -0.9 -1.2 conserved hypothetical protein compare
Psest_1167 -0.9 -1.1 hypothetical protein compare
Psest_1144 -0.9 -1.6 AmpG-related permease compare
Psest_0136 -0.9 -5.7 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_0292 -0.9 -1.5 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_0411 -0.8 -5.4 biotin synthetase compare
Psest_0066 -0.8 -1.7 Protein of unknown function (DUF3060). compare
Psest_3146 -0.8 -1.4 hypothetical protein compare
Psest_3339 -0.8 -3.9 Signal transduction histidine kinase compare
Psest_1008 -0.8 -1.2 hypothetical protein compare
Psest_0137 -0.8 -4.2 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_1082 -0.8 -2.0 Enoyl-CoA hydratase/carnithine racemase compare
Psest_2719 -0.8 -1.6 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_0716 -0.8 -2.0 Protein of unknown function (DUF3094). compare
Psest_2810 -0.8 -3.8 5'/3'-nucleotidase SurE compare
Psest_1491 -0.8 -2.4 Cold shock proteins compare
Psest_0067 -0.8 -2.3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Psest_0359 -0.8 -2.1 Transcriptional regulators compare
Psest_1313 -0.8 -1.6 Uncharacterized conserved small protein compare
Psest_0393 -0.8 -3.7 Methylase of chemotaxis methyl-accepting proteins compare
Psest_3931 -0.8 -3.3 Signal transduction histidine kinase, nitrogen specific compare
Psest_3092 -0.8 -1.6 ribonuclease III, bacterial compare
Psest_1022 -0.8 -4.9 Thiol:disulfide interchange protein compare
Psest_1518 -0.7 -2.4 tRNA_Ser_CGA compare
Psest_1909 -0.7 -3.2 Phosphohistidine phosphatase SixA compare
Psest_2293 -0.7 -1.3 hypothetical protein compare
Psest_3927 -0.7 -1.7 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_2520 -0.7 -1.1 Predicted SAM-dependent methyltransferase compare
Psest_2911 -0.7 -1.6 Protein of unknown function (DUF2945). compare
Psest_2945 -0.7 -1.1 septum site-determining protein MinC compare
Psest_4045 -0.7 -3.1 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen compare
Psest_1601 -0.7 -2.0 Signal transduction histidine kinase compare
Psest_2446 -0.7 -2.1 acetyl-CoA acetyltransferases compare
Psest_1510 -0.7 -2.4 Putative Zn-dependent protease, contains TPR repeats compare
Psest_1679 -0.7 -1.3 ribonuclease, Rne/Rng family compare
Psest_4363 -0.7 -3.6 ATPases involved in chromosome partitioning compare
Psest_1873 -0.7 -3.3 Predicted permease, DMT superfamily compare
Psest_2530 -0.7 -2.5 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_1957 -0.7 -4.9 outer membrane porin, OprD family. compare
Psest_3113 -0.7 -1.4 electron transport complex, RnfABCDGE type, B subunit compare
Psest_4390 -0.7 -2.1 hypothetical protein compare
Psest_3878 -0.7 -1.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2414 -0.7 -3.1 TolR protein compare
Psest_2229 -0.7 -1.9 Uncharacterized protein conserved in bacteria compare
Psest_2935 -0.6 -1.5 hypothetical protein compare
Psest_0306 -0.6 -5.2 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_0412 -0.6 -4.6 8-amino-7-oxononanoate synthase compare
Psest_2334 -0.6 -5.1 Uncharacterized protein conserved in bacteria compare
Psest_1657 -0.6 -1.2 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_0170 -0.6 -2.8 5,10-methenyltetrahydrofolate synthetase compare
Psest_1985 -0.6 -2.8 histidinol-phosphate aminotransferase compare
Psest_3536 -0.6 -1.3 hypothetical protein compare
Psest_2892 -0.6 -2.1 Transcriptional regulator compare
Psest_1660 -0.6 -1.2 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_4064 -0.6 -1.7 Lactate dehydrogenase and related dehydrogenases compare
Psest_0491 -0.6 -4.5 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3937 -0.6 -1.2 ATP-dependent protease HslVU, ATPase subunit compare
Psest_0482 -0.6 -2.8 yqiA-like hydrolase, affects the cell envelope (from data) compare
Psest_3731 -0.6 -4.6 exopolyphosphatase compare
Psest_1111 -0.6 -1.8 Flp pilus assembly protein TadD, contains TPR repeats compare
Psest_3932 -0.6 -2.8 nitrogen regulation protein NR(I) compare
Psest_0414 -0.6 -2.0 biotin biosynthesis protein BioC compare
Psest_0872 -0.6 -0.9 Helix-turn-helix. compare
Psest_4364 -0.6 -1.9 16S rRNA (guanine(527)-N(7))-methyltransferase GidB compare
Psest_3766 -0.6 -1.6 Uncharacterized protein conserved in bacteria compare
Psest_0693 -0.6 -5.5 His Kinase A (phosphoacceptor) domain./PAS fold./Response regulator receiver domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_3047 -0.6 -0.8 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_0164 -0.6 -0.6 Glutaredoxin, GrxC family compare
Psest_0191 -0.6 -0.5 PAS domain S-box compare
Psest_2711 -0.6 -1.6 PilZ domain. compare
Psest_1879 -0.6 -1.7 Trk-type K+ transport systems, membrane components compare
Psest_1282 -0.6 -1.5 Amidases related to nicotinamidase compare
Psest_1627 -0.6 -3.8 Superfamily II DNA and RNA helicases compare
Psest_3958 -0.6 -2.7 Predicted Fe-S-cluster oxidoreductase compare
Psest_0867 -0.6 -0.8 hypothetical protein compare
Psest_0368 -0.6 -1.2 Transcriptional regulator compare
Psest_3288 -0.6 -4.1 type IV-A pilus assembly ATPase PilB compare
Psest_3045 -0.6 -1.1 Cold shock proteins compare
Psest_3882 -0.6 -4.2 Opacity protein and related surface antigens compare
Psest_0708 -0.6 -1.0 outer membrane assembly lipoprotein YfiO compare
Psest_3550 -0.6 -1.4 3,4-dihydroxy-2-butanone 4-phosphate synthase compare
Psest_2531 -0.6 -3.9 cytochrome c oxidase accessory protein FixG compare
Psest_0362 -0.6 -1.5 TRAP-type C4-dicarboxylate transport system, small permease component compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source L-Malic acid disodium salt monohydrate in Pseudomonas stutzeri RCH2

For carbon source L-Malic acid disodium salt monohydrate across organisms