Experiment set12H18 for Pseudomonas stutzeri RCH2

Compare to:

L-Leucine carbon source

200 most important genes:

  gene name fitness t score description  
Psest_1082 -7.6 -4.0 Enoyl-CoA hydratase/carnithine racemase compare
Psest_3516 -7.2 -9.9 Leucine dehydrogenase (EC 1.4.1.9) (from data) compare
Psest_0152 -6.9 -6.8 Imidazoleglycerol-phosphate dehydratase compare
Psest_2584 -6.8 -4.7 Phosphoribosylanthranilate isomerase compare
Psest_1037 -6.7 -4.6 acetolactate synthase, small subunit compare
Psest_3647 -6.4 -8.8 Indole-3-glycerol phosphate synthase compare
Psest_1078 -6.4 -6.2 acetyl-CoA:acetoacetate CoA transferase, A subunit (EC 2.8.3.8) (from data) compare
Psest_1084 -6.3 -12.2 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) conserved
Psest_0155 -6.2 -8.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3648 -6.1 -9.3 anthranilate phosphoribosyltransferase compare
Psest_1080 -6.0 -12.8 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Psest_2988 -6.0 -5.8 aspartate kinase, monofunctional class compare
Psest_1083 -5.9 -15.8 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) conserved
Psest_0508 -5.9 -12.0 gamma-glutamyl phosphate reductase compare
Psest_3517 -5.9 -21.1 branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) conserved
Psest_1081 -5.7 -9.0 hypothetical protein compare
Psest_0063 -5.7 -13.2 tryptophan synthase, beta subunit compare
Psest_3650 -5.7 -18.2 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3298 -5.6 -14.6 histidinol dehydrogenase compare
Psest_3732 -5.6 -10.7 polyphosphate kinase 1 compare
Psest_3384 -5.6 -12.4 glutamate 5-kinase compare
Psest_1292 -5.6 -3.8 monothiol glutaredoxin, Grx4 family compare
Psest_0062 -5.5 -12.1 tryptophan synthase, alpha subunit compare
Psest_3299 -5.5 -18.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_1077 -5.5 -12.1 acetyl-CoA:acetoacetate CoA transferase, B subunit (EC 2.8.3.8) (from data) conserved
Psest_2014 -5.4 -10.5 Isocitrate lyase (EC 4.1.3.1) (from data) conserved
Psest_3998 -5.3 -5.1 glutamate--cysteine ligase compare
Psest_2578 -5.2 -18.2 O-succinylhomoserine sulfhydrylase compare
Psest_0153 -5.1 -16.9 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_1079 -5.0 -3.4 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_3944 -4.6 -5.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_3943 -4.6 -7.1 Phosphoribosyl-AMP cyclohydrolase compare
Psest_3864 -4.5 -19.4 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0280 -4.5 -17.1 homoserine O-acetyltransferase compare
Psest_0687 -4.2 -9.9 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3862 -4.2 -20.0 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0279 -4.0 -7.6 methionine biosynthesis protein MetW compare
Psest_3518 -3.9 -1.7 Transcriptional regulators compare
Psest_0313 -3.7 -9.8 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_0296 -3.7 -11.8 glutathione synthetase, prokaryotic compare
Psest_1473 -3.7 -10.1 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_2579 -3.6 -4.9 amidophosphoribosyltransferase compare
Psest_1814 -3.5 -23.3 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_1772 -3.2 -6.2 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0170 -3.0 -9.5 5,10-methenyltetrahydrofolate synthetase compare
Psest_1012 -3.0 -6.8 Signal transduction histidine kinase compare
Psest_3322 -2.9 -19.5 TIGR02099 family protein compare
Psest_3960 -2.9 -2.0 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_0417 -2.9 -3.4 Acyl-CoA dehydrogenases compare
Psest_1765 -2.8 -10.7 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_4083 -2.8 -19.0 Predicted permease compare
Psest_3307 -2.8 -9.3 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_0297 -2.7 -6.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0999 -2.6 -3.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3304 -2.6 -8.0 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_3809 -2.6 -8.1 hypothetical protein compare
Psest_3301 -2.6 -5.2 Predicted transcriptional regulator, BolA superfamily compare
Psest_3305 -2.6 -10.1 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_3159 -2.6 -4.9 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1704 -2.5 -1.7 Dehydrogenases (flavoproteins) compare
Psest_1474 -2.5 -1.7 phosphoribosylaminoimidazole synthetase compare
Psest_3806 -2.5 -9.9 Phosphomannomutase compare
Psest_3866 -2.4 -15.3 threonine ammonia-lyase, biosynthetic, long form compare
Psest_1013 -2.4 -2.9 phosphoribosylamine--glycine ligase compare
Psest_2712 -2.4 -5.7 Surface lipoprotein compare
Psest_3288 -2.4 -14.9 type IV-A pilus assembly ATPase PilB compare
Psest_1695 -2.4 -4.8 Tfp pilus assembly protein PilZ compare
Psest_0489 -2.4 -1.6 phosphoserine phosphatase SerB compare
Psest_1295 -2.4 -9.2 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0248 -2.3 -8.8 Transcriptional regulator compare
Psest_1510 -2.3 -5.6 Putative Zn-dependent protease, contains TPR repeats compare
Psest_3670 -2.3 -10.7 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_0491 -2.3 -12.0 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_1567 -2.2 -5.5 Transcriptional regulator compare
Psest_3721 -2.2 -10.3 Malic enzyme compare
Psest_3306 -2.2 -6.5 conserved hypothetical integral membrane protein compare
Psest_3716 -2.2 -12.5 Tfp pilus assembly protein PilP compare
Psest_2104 -2.2 -2.5 IscR-regulated protein YhgI compare
Psest_3303 -2.1 -6.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_4191 -2.1 -2.9 Transcriptional regulator compare
Psest_0300 -2.1 -9.4 Methyl-accepting chemotaxis protein compare
Psest_0354 -2.1 -12.2 Malate synthase G (EC 2.3.3.9) (from data) compare
Psest_2945 -2.1 -2.4 septum site-determining protein MinC compare
Psest_3718 -2.1 -7.6 Tfp pilus assembly protein PilN compare
Psest_1260 -2.0 -10.1 type IV pilus biogenesis/stability protein PilW compare
Psest_1640 -2.0 -10.3 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_3810 -2.0 -1.4 orotate phosphoribosyltransferase compare
Psest_1661 -2.0 -2.6 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_1163 -1.9 -5.8 diguanylate cyclase (GGDEF) domain compare
Psest_2067 -1.9 -2.0 ABC-type oligopeptide transport system, periplasmic component compare
Psest_3719 -1.8 -11.1 type IV pilus assembly protein PilM compare
Psest_3226 -1.8 -1.6 Predicted membrane protein compare
Psest_3287 -1.8 -6.1 Type II secretory pathway, component PulF compare
Psest_3715 -1.8 -13.2 type IV pilus secretin (or competence protein) PilQ compare
Psest_2967 -1.8 -2.9 flagellar basal-body rod protein FlgC compare
Psest_4005 -1.8 -7.1 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB compare
Psest_0285 -1.7 -8.9 pilus retraction protein PilT compare
Psest_3289 -1.7 -8.6 prepilin-type N-terminal cleavage/methylation domain compare
Psest_0442 -1.7 -2.8 ATPases of the AAA+ class compare
Psest_2944 -1.7 -1.6 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_0024 -1.7 -8.7 LysM domain. compare
Psest_0725 -1.7 -2.8 Negative regulator of beta-lactamase expression compare
Psest_3375 -1.6 -8.8 prepilin-type N-terminal cleavage/methylation domain compare
Psest_0325 -1.6 -8.7 Putative threonine efflux protein compare
Psest_3818 -1.6 -6.0 endoribonuclease L-PSP, putative compare
Psest_1402 -1.6 -10.6 Putative threonine efflux protein compare
Psest_0705 -1.6 -11.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3317 -1.6 -3.7 Phosphotransferase System HPr (HPr) Family compare
Psest_0706 -1.6 -7.9 His Kinase A (phosphoacceptor) domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_2968 -1.5 -6.8 flagellar basal-body rod protein FlgB compare
Psest_4097 -1.5 -9.0 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3766 -1.5 -2.8 Uncharacterized protein conserved in bacteria compare
Psest_3717 -1.5 -6.3 Tfp pilus assembly protein PilO compare
Psest_1403 -1.4 -8.1 Transcriptional regulators compare
Psest_1947 -1.4 -0.9 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_1857 -1.4 -9.7 Isocitrate dehydrogenase kinase/phosphatase conserved
Psest_1724 -1.4 -3.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_3395 -1.4 -1.4 hypothetical protein compare
Psest_2240 -1.3 -1.8 hypothetical protein compare
Psest_3937 -1.3 -2.0 ATP-dependent protease HslVU, ATPase subunit compare
Psest_2586 -1.3 -11.0 FimV N-terminal domain compare
Psest_0520 -1.3 -1.1 hypothetical protein compare
Psest_3286 -1.2 -5.3 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_0302 -1.2 -9.1 Chemotaxis protein histidine kinase and related kinases compare
Psest_0393 -1.2 -5.8 Methylase of chemotaxis methyl-accepting proteins compare
Psest_2719 -1.2 -1.9 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_1813 -1.2 -7.7 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_3180 -1.2 -7.2 Exonuclease I compare
Psest_4044 -1.1 -3.4 type I site-specific deoxyribonuclease, HsdR family compare
Psest_4287 -1.1 -4.4 Predicted glutamine amidotransferases compare
Psest_0708 -1.1 -1.4 outer membrane assembly lipoprotein YfiO compare
Psest_2545 -1.1 -3.3 recombination protein RecR compare
Psest_3042 -1.1 -1.5 Nitrate reductase cytochrome c-type subunit compare
Psest_2940 -1.1 -1.6 Predicted membrane protein compare
Psest_1496 -1.1 -1.2 Holliday junction DNA helicase, RuvA subunit compare
Psest_0309 -1.1 -1.6 RND family efflux transporter, MFP subunit compare
Psest_2083 -1.1 -5.4 Putative sterol carrier protein compare
Psest_3884 -1.1 -1.0 Signal transduction histidine kinase compare
Psest_3047 -1.1 -1.2 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_1815 -1.0 -7.8 pseudaminic acid synthase compare
Psest_2708 -1.0 -6.4 transaldolase compare
Psest_2680 -1.0 -4.7 transcriptional regulator, BolA protein family compare
Psest_3954 -1.0 -2.6 Small protein A (tmRNA-binding) compare
Psest_4209 -1.0 -2.1 Uncharacterized conserved small protein compare
Psest_0193 -1.0 -1.2 conserved hypothetical protein compare
Psest_2806 -0.9 -5.5 RNA polymerase sigma factor RpoS compare
Psest_2651 -0.9 -2.6 DNA topoisomerase I, bacterial compare
Psest_1000 -0.9 -5.6 PAS domain S-box compare
Psest_0175 -0.9 -4.9 Xaa-Pro aminopeptidase compare
Psest_0359 -0.9 -2.4 Transcriptional regulators compare
Psest_4098 -0.9 -2.0 Superfamily I DNA and RNA helicases compare
Psest_3323 -0.8 -2.7 ribonuclease, Rne/Rng family compare
Psest_3910 -0.8 -1.2 Uncharacterized protein conserved in bacteria compare
Psest_1660 -0.8 -1.7 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_0993 -0.8 -5.5 Glucose-6-phosphate isomerase compare
Psest_2645 -0.8 -4.3 Transcriptional regulator compare
Psest_2026 -0.8 -5.9 Uncharacterized conserved protein compare
Psest_1918 -0.8 -4.5 Calcineurin-like phosphoesterase. conserved
Psest_2744 -0.8 -1.4 Uncharacterized conserved protein compare
Psest_1994 -0.8 -2.4 Amidases related to nicotinamidase compare
Psest_0707 -0.8 -3.2 MYND finger. compare
Psest_0326 -0.8 -5.2 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_2278 -0.8 -1.7 coenzyme PQQ biosynthesis protein PqqD compare
Psest_2277 -0.8 -2.1 coenzyme PQQ biosynthesis protein A compare
Psest_0191 -0.8 -1.0 PAS domain S-box compare
Psest_0740 -0.8 -1.5 Transcriptional regulator compare
Psest_3991 -0.8 -2.0 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Psest_0851 -0.8 -5.3 Transcriptional regulators compare
Psest_2591 -0.8 -1.5 3-isopropylmalate dehydratase, large subunit compare
Psest_1677 -0.8 -1.4 Protein-tyrosine-phosphatase compare
Psest_1516 -0.8 -2.2 Uncharacterized lipoprotein compare
Psest_0066 -0.8 -1.2 Protein of unknown function (DUF3060). compare
Psest_1824 -0.7 -2.0 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_2232 -0.7 -5.7 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_1822 -0.7 -4.7 Glycosyltransferases involved in cell wall biogenesis compare
Psest_1527 -0.7 -5.6 Na+/proline symporter compare
Psest_1518 -0.7 -2.0 tRNA_Ser_CGA compare
Psest_0445 -0.7 -5.3 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_2911 -0.7 -1.9 Protein of unknown function (DUF2945). compare
Psest_2864 -0.7 -2.4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2329 -0.7 -5.6 Transcriptional regulator compare
Psest_4084 -0.7 -5.5 oxaloacetate decarboxylase alpha subunit compare
Psest_2507 -0.7 -5.4 Flagellin and related hook-associated proteins compare
Psest_0294 -0.7 -3.1 Putative transcriptional regulator compare
Psest_1514 -0.7 -4.5 Glycine cleavage system regulatory protein compare
Psest_0347 -0.7 -5.7 large component of pyruvate/D-alanine transporter (actP-like) (from data) compare
Psest_0466 -0.7 -1.8 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0141 -0.7 -3.3 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_2324 -0.7 -5.7 hypothetical protein compare
Psest_0257 -0.7 -1.2 Predicted Zn-dependent peptidases compare
Psest_2325 -0.7 -4.2 alpha-L-glutamate ligase-related protein compare
Psest_0494 -0.7 -3.9 Rhodanese-related sulfurtransferase compare
Psest_1001 -0.7 -1.6 hypothetical protein compare
Psest_1750 -0.7 -2.4 Protein of unknown function (DUF2802). compare
Psest_3231 -0.7 -1.2 hypothetical protein compare
Psest_1076 -0.7 -2.3 acetyl-CoA acetyltransferases compare
Psest_4114 -0.7 -2.6 hypothetical protein compare
Psest_1404 -0.7 -3.5 Methyltransferase domain. compare
Psest_0498 -0.7 -1.0 ribosome small subunit-dependent GTPase A compare
Psest_2027 -0.7 -4.6 ATP-dependent Clp protease ATP-binding subunit clpA compare


Specific Phenotypes

For 14 genes in this experiment

For carbon source L-Leucine in Pseudomonas stutzeri RCH2

For carbon source L-Leucine across organisms