Experiment set12H17 for Pseudomonas stutzeri RCH2

Compare to:

L-Leucine carbon source

200 most important genes:

  gene name fitness t score description  
Psest_0155 -6.7 -4.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3647 -6.5 -7.8 Indole-3-glycerol phosphate synthase compare
Psest_1078 -6.5 -6.3 acetyl-CoA:acetoacetate CoA transferase, A subunit (EC 2.8.3.8) (from data) compare
Psest_1077 -6.4 -11.5 acetyl-CoA:acetoacetate CoA transferase, B subunit (EC 2.8.3.8) (from data) conserved
Psest_0508 -6.4 -10.7 gamma-glutamyl phosphate reductase compare
Psest_0152 -6.2 -7.4 Imidazoleglycerol-phosphate dehydratase compare
Psest_2988 -6.1 -4.2 aspartate kinase, monofunctional class compare
Psest_1084 -6.1 -13.0 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) conserved
Psest_0063 -6.1 -11.6 tryptophan synthase, beta subunit compare
Psest_0062 -6.0 -14.0 tryptophan synthase, alpha subunit compare
Psest_1081 -6.0 -9.1 hypothetical protein compare
Psest_2584 -5.9 -8.1 Phosphoribosylanthranilate isomerase compare
Psest_3650 -5.9 -16.6 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_1080 -5.9 -13.1 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Psest_2014 -5.8 -10.3 Isocitrate lyase (EC 4.1.3.1) (from data) conserved
Psest_3298 -5.7 -13.9 histidinol dehydrogenase compare
Psest_3299 -5.7 -16.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_3648 -5.6 -11.4 anthranilate phosphoribosyltransferase compare
Psest_1083 -5.6 -14.5 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) conserved
Psest_3732 -5.6 -10.1 polyphosphate kinase 1 compare
Psest_3517 -5.5 -21.3 branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) conserved
Psest_3384 -5.4 -12.0 glutamate 5-kinase compare
Psest_0153 -5.3 -16.5 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_1082 -5.3 -3.9 Enoyl-CoA hydratase/carnithine racemase compare
Psest_3998 -5.2 -5.1 glutamate--cysteine ligase compare
Psest_0280 -5.1 -20.4 homoserine O-acetyltransferase compare
Psest_3943 -5.0 -7.5 Phosphoribosyl-AMP cyclohydrolase compare
Psest_1079 -4.9 -3.4 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_0687 -4.9 -11.8 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_1292 -4.8 -8.7 monothiol glutaredoxin, Grx4 family compare
Psest_3516 -4.7 -12.8 Leucine dehydrogenase (EC 1.4.1.9) (from data) compare
Psest_3864 -4.6 -19.1 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0279 -4.6 -9.0 methionine biosynthesis protein MetW compare
Psest_2578 -4.2 -17.9 O-succinylhomoserine sulfhydrylase compare
Psest_1772 -4.1 -7.8 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3862 -4.0 -17.1 phosphoenolpyruvate-protein phosphotransferase compare
Psest_1473 -4.0 -10.7 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0296 -3.9 -13.9 glutathione synthetase, prokaryotic compare
Psest_3944 -3.9 -5.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_3518 -3.9 -1.8 Transcriptional regulators compare
Psest_0313 -3.8 -9.7 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_1037 -3.7 -2.4 acetolactate synthase, small subunit compare
Psest_1814 -3.7 -23.6 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_3305 -3.6 -11.2 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_2579 -3.5 -4.8 amidophosphoribosyltransferase compare
Psest_3307 -3.5 -9.4 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_1765 -3.3 -11.9 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0417 -3.2 -2.2 Acyl-CoA dehydrogenases compare
Psest_0999 -3.2 -2.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2712 -3.1 -7.3 Surface lipoprotein compare
Psest_3322 -3.1 -20.5 TIGR02099 family protein compare
Psest_1695 -3.1 -7.4 Tfp pilus assembly protein PilZ compare
Psest_4083 -3.1 -16.9 Predicted permease compare
Psest_3670 -3.0 -11.9 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_4219 -3.0 -3.5 DNA polymerase I compare
Psest_0170 -3.0 -9.2 5,10-methenyltetrahydrofolate synthetase compare
Psest_0297 -2.9 -5.7 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2104 -2.9 -1.9 IscR-regulated protein YhgI compare
Psest_3304 -2.8 -6.4 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_3288 -2.8 -17.3 type IV-A pilus assembly ATPase PilB compare
Psest_1295 -2.8 -9.3 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_1567 -2.7 -8.5 Transcriptional regulator compare
Psest_3303 -2.6 -6.7 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_3159 -2.6 -5.0 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0491 -2.6 -13.4 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_1013 -2.6 -2.5 phosphoribosylamine--glycine ligase compare
Psest_3717 -2.5 -8.6 Tfp pilus assembly protein PilO compare
Psest_3809 -2.5 -5.9 hypothetical protein compare
Psest_1474 -2.5 -1.7 phosphoribosylaminoimidazole synthetase compare
Psest_3718 -2.5 -9.9 Tfp pilus assembly protein PilN compare
Psest_1012 -2.5 -6.4 Signal transduction histidine kinase compare
Psest_1704 -2.4 -1.6 Dehydrogenases (flavoproteins) compare
Psest_3306 -2.4 -5.5 conserved hypothetical integral membrane protein compare
Psest_1640 -2.4 -13.3 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_3866 -2.4 -13.8 threonine ammonia-lyase, biosynthetic, long form compare
Psest_0300 -2.4 -9.7 Methyl-accepting chemotaxis protein compare
Psest_3806 -2.4 -9.0 Phosphomannomutase compare
Psest_0489 -2.3 -1.6 phosphoserine phosphatase SerB compare
Psest_3716 -2.3 -10.8 Tfp pilus assembly protein PilP compare
Psest_3721 -2.3 -10.6 Malic enzyme compare
Psest_1260 -2.3 -9.3 type IV pilus biogenesis/stability protein PilW compare
Psest_1510 -2.2 -5.6 Putative Zn-dependent protease, contains TPR repeats compare
Psest_3715 -2.2 -15.8 type IV pilus secretin (or competence protein) PilQ compare
Psest_3146 -2.2 -3.5 hypothetical protein compare
Psest_3301 -2.2 -5.2 Predicted transcriptional regulator, BolA superfamily compare
Psest_3129 -2.2 -2.4 tyrosine recombinase XerD compare
Psest_0354 -2.1 -13.3 Malate synthase G (EC 2.3.3.9) (from data) compare
Psest_0285 -2.1 -11.3 pilus retraction protein PilT compare
Psest_3375 -2.1 -8.1 prepilin-type N-terminal cleavage/methylation domain compare
Psest_0259 -2.1 -1.6 cell division ATP-binding protein FtsE compare
Psest_0024 -2.1 -10.7 LysM domain. compare
Psest_3287 -2.0 -6.5 Type II secretory pathway, component PulF compare
Psest_3226 -2.0 -1.8 Predicted membrane protein compare
Psest_3810 -1.9 -1.3 orotate phosphoribosyltransferase compare
Psest_4005 -1.9 -7.4 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB compare
Psest_1163 -1.9 -4.4 diguanylate cyclase (GGDEF) domain compare
Psest_0706 -1.9 -11.6 His Kinase A (phosphoacceptor) domain./Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase. compare
Psest_0248 -1.9 -7.0 Transcriptional regulator compare
Psest_3960 -1.9 -1.3 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_2967 -1.8 -2.4 flagellar basal-body rod protein FlgC compare
Psest_1402 -1.8 -11.6 Putative threonine efflux protein compare
Psest_1403 -1.8 -7.7 Transcriptional regulators compare
Psest_3317 -1.8 -6.1 Phosphotransferase System HPr (HPr) Family compare
Psest_3123 -1.8 -2.1 dihydroorotase, homodimeric type compare
Psest_3719 -1.7 -11.0 type IV pilus assembly protein PilM compare
Psest_4097 -1.7 -11.0 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_0325 -1.7 -10.0 Putative threonine efflux protein compare
Psest_0705 -1.7 -11.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2651 -1.7 -4.7 DNA topoisomerase I, bacterial compare
Psest_2646 -1.7 -1.9 SOS regulatory protein LexA compare
Psest_3092 -1.6 -2.3 ribonuclease III, bacterial compare
Psest_3047 -1.6 -1.8 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_3289 -1.6 -6.8 prepilin-type N-terminal cleavage/methylation domain compare
Psest_1496 -1.6 -1.7 Holliday junction DNA helicase, RuvA subunit compare
Psest_2067 -1.5 -1.5 ABC-type oligopeptide transport system, periplasmic component compare
Psest_1813 -1.5 -8.6 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_2586 -1.4 -12.8 FimV N-terminal domain compare
Psest_0212 -1.4 -2.3 exodeoxyribonuclease V, gamma subunit compare
Psest_3818 -1.4 -5.7 endoribonuclease L-PSP, putative compare
Psest_1857 -1.4 -9.5 Isocitrate dehydrogenase kinase/phosphatase conserved
Psest_1661 -1.4 -2.3 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_0442 -1.3 -2.6 ATPases of the AAA+ class compare
Psest_0393 -1.3 -5.9 Methylase of chemotaxis methyl-accepting proteins compare
Psest_1947 -1.3 -0.9 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_2968 -1.3 -4.8 flagellar basal-body rod protein FlgB compare
Psest_2277 -1.3 -2.7 coenzyme PQQ biosynthesis protein A compare
Psest_0737 -1.3 -1.2 Cu(I)-responsive transcriptional regulator compare
Psest_1724 -1.3 -2.9 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_2083 -1.3 -4.3 Putative sterol carrier protein compare
Psest_2809 -1.3 -2.2 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_0193 -1.3 -1.6 conserved hypothetical protein compare
Psest_4191 -1.2 -2.4 Transcriptional regulator compare
Psest_1918 -1.2 -5.1 Calcineurin-like phosphoesterase. conserved
Psest_1000 -1.2 -6.8 PAS domain S-box compare
Psest_1815 -1.2 -9.2 pseudaminic acid synthase compare
Psest_3286 -1.2 -4.3 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_0346 -1.2 -3.0 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_2719 -1.2 -1.9 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_0302 -1.1 -8.6 Chemotaxis protein histidine kinase and related kinases compare
Psest_0257 -1.1 -2.7 Predicted Zn-dependent peptidases compare
Psest_0359 -1.1 -2.4 Transcriptional regulators compare
Psest_3180 -1.1 -6.4 Exonuclease I compare
Psest_2864 -1.1 -4.4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_0326 -1.1 -6.6 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_4044 -1.1 -3.1 type I site-specific deoxyribonuclease, HsdR family compare
Psest_2708 -1.1 -6.3 transaldolase compare
Psest_2806 -1.1 -5.2 RNA polymerase sigma factor RpoS compare
Psest_1242 -1.1 -2.6 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_3177 -1.1 -1.8 hypothetical protein compare
Psest_1774 -1.0 -1.9 Glutathione peroxidase compare
Psest_2718 -1.0 -1.7 hypothetical protein compare
Psest_4274 -1.0 -3.1 hypothetical protein compare
Psest_2786 -1.0 -1.3 Domain of unknown function (DUF3597). compare
Psest_3766 -1.0 -2.2 Uncharacterized protein conserved in bacteria compare
Psest_2232 -1.0 -7.5 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_4287 -1.0 -3.8 Predicted glutamine amidotransferases compare
Psest_0993 -1.0 -6.4 Glucose-6-phosphate isomerase compare
Psest_4363 -0.9 -4.9 ATPases involved in chromosome partitioning compare
Psest_2123 -0.9 -1.5 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_0537 -0.9 -1.7 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_0969 -0.9 -1.2 transcription elongation factor GreA compare
Psest_2680 -0.9 -5.4 transcriptional regulator, BolA protein family compare
Psest_1750 -0.9 -1.9 Protein of unknown function (DUF2802). compare
Psest_1001 -0.9 -2.2 hypothetical protein compare
Psest_3338 -0.9 -1.0 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_1514 -0.9 -4.5 Glycine cleavage system regulatory protein compare
Psest_1945 -0.9 -3.8 hypothetical protein compare
Psest_2329 -0.9 -6.8 Transcriptional regulator compare
Psest_1870 -0.9 -1.4 Transcriptional regulators compare
Psest_1527 -0.9 -6.5 Na+/proline symporter compare
Psest_1642 -0.8 -4.1 Uncharacterized protein conserved in bacteria compare
Psest_0707 -0.8 -3.3 MYND finger. compare
Psest_2324 -0.8 -7.1 hypothetical protein compare
Psest_3735 -0.8 -1.9 uncharacterized domain 1 compare
Psest_3649 -0.8 -4.2 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3323 -0.8 -3.1 ribonuclease, Rne/Rng family compare
Psest_3478 -0.8 -1.1 Cytochrome B561 compare
Psest_4085 -0.8 -6.2 Biotin carboxylase compare
Psest_3002 -0.8 -2.2 Putative translation initiation inhibitor, yjgF family compare
Psest_3700 -0.8 -1.3 hypothetical protein compare
Psest_1919 -0.8 -2.0 Uncharacterized membrane protein (homolog of Drosophila rhomboid) compare
Psest_2940 -0.8 -1.1 Predicted membrane protein compare
Psest_2027 -0.8 -5.3 ATP-dependent Clp protease ATP-binding subunit clpA compare
Psest_0347 -0.8 -6.0 large component of pyruvate/D-alanine transporter (actP-like) (from data) compare
Psest_2343 -0.8 -3.0 Mg-dependent DNase compare
Psest_2407 -0.8 -1.9 nitrite reductase [NAD(P)H], small subunit compare
Psest_3374 -0.8 -5.4 Tfp pilus assembly protein, tip-associated adhesin PilY1 compare
Psest_2026 -0.8 -5.0 Uncharacterized conserved protein compare
Psest_0262 -0.8 -6.8 PAS domain S-box compare
Psest_4084 -0.8 -5.5 oxaloacetate decarboxylase alpha subunit compare
Psest_0067 -0.7 -1.7 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Psest_0334 -0.7 -2.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_4098 -0.7 -2.0 Superfamily I DNA and RNA helicases compare
Psest_2507 -0.7 -5.4 Flagellin and related hook-associated proteins compare
Psest_2590 -0.7 -1.1 3-isopropylmalate dehydratase, small subunit compare
Psest_1404 -0.7 -3.6 Methyltransferase domain. compare
Psest_2323 -0.7 -5.6 Uncharacterized protein conserved in archaea compare
Psest_2566 -0.7 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_0851 -0.7 -5.0 Transcriptional regulators compare
Psest_0060 -0.7 -1.5 Predicted Fe-S protein compare


Specific Phenotypes

For 15 genes in this experiment

For carbon source L-Leucine in Pseudomonas stutzeri RCH2

For carbon source L-Leucine across organisms