Experiment set12H15 for Pseudomonas stutzeri RCH2

Compare to:

L-Isoleucine carbon source

200 most important genes:

  gene name fitness t score description  
Psest_0279 -6.8 -6.6 methionine biosynthesis protein MetW compare
Psest_0155 -6.2 -6.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_2590 -5.9 -2.2 3-isopropylmalate dehydratase, small subunit compare
Psest_3298 -5.9 -12.7 histidinol dehydrogenase compare
Psest_2591 -5.8 -5.6 3-isopropylmalate dehydratase, large subunit compare
Psest_3648 -5.8 -9.7 anthranilate phosphoribosyltransferase compare
Psest_0325 -5.6 -13.6 Putative threonine efflux protein compare
Psest_3517 -5.6 -21.9 branched-chain ketoacid ferredoxin reductase (EC 1.2.7.7) active on 4-methyl-2-oxopentanoate, (S)-3-methyl-2-oxopentanoate, or 3-methyl-2-oxobutanoate (from data) compare
Psest_3647 -5.5 -10.0 Indole-3-glycerol phosphate synthase compare
Psest_2578 -5.5 -16.3 O-succinylhomoserine sulfhydrylase compare
Psest_1640 -5.4 -18.4 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_2584 -5.2 -9.9 Phosphoribosylanthranilate isomerase compare
Psest_0062 -5.1 -16.2 tryptophan synthase, alpha subunit compare
Psest_2448 -5.1 -7.8 AraC-type DNA-binding domain-containing proteins conserved
Psest_0063 -5.1 -14.6 tryptophan synthase, beta subunit compare
Psest_3650 -5.0 -17.7 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0280 -5.0 -14.6 homoserine O-acetyltransferase compare
Psest_3299 -4.9 -17.1 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_1292 -4.9 -8.1 monothiol glutaredoxin, Grx4 family compare
Psest_0313 -4.8 -8.6 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3998 -4.8 -8.0 glutamate--cysteine ligase compare
Psest_1037 -4.8 -5.7 acetolactate synthase, small subunit compare
Psest_2446 -4.7 -5.0 acetyl-CoA acetyltransferases compare
Psest_0152 -4.5 -5.7 Imidazoleglycerol-phosphate dehydratase compare
Psest_2320 -4.5 -9.4 2-methylcitrate synthase/citrate synthase II conserved
Psest_2589 -4.5 -12.8 3-isopropylmalate dehydrogenase compare
Psest_0450 -4.4 -11.7 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) conserved
Psest_3943 -4.3 -7.7 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0326 -4.3 -13.7 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_3384 -4.3 -9.7 glutamate 5-kinase compare
Psest_0153 -4.2 -15.5 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0508 -4.2 -9.9 gamma-glutamyl phosphate reductase compare
Psest_0687 -4.2 -12.5 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3518 -3.9 -2.0 Transcriptional regulators compare
Psest_2579 -3.6 -3.5 amidophosphoribosyltransferase compare
Psest_3516 -3.5 -10.3 Leucine dehydrogenase (EC 1.4.1.9) (from data) compare
Psest_2445 -3.5 -10.5 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) conserved
Psest_2988 -3.4 -8.6 aspartate kinase, monofunctional class compare
Psest_2088 -3.3 -2.8 Uncharacterized protein conserved in bacteria compare
Psest_2872 -3.3 -3.1 protein RecA compare
Psest_0999 -3.1 -2.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3864 -3.1 -14.0 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0327 -2.9 -5.4 Transcriptional regulator compare
Psest_0296 -2.8 -11.4 glutathione synthetase, prokaryotic compare
Psest_3670 -2.6 -13.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_1657 -2.6 -3.0 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_3159 -2.6 -4.6 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1704 -2.4 -1.6 Dehydrogenases (flavoproteins) compare
Psest_3944 -2.3 -6.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0489 -2.3 -1.6 phosphoserine phosphatase SerB compare
Psest_1474 -2.3 -2.2 phosphoribosylaminoimidazole synthetase compare
Psest_1656 -2.3 -3.2 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_0571 -2.2 -8.6 Transcriptional regulators conserved
Psest_1505 -2.2 -2.5 Organic radical activating enzymes compare
Psest_1013 -2.2 -3.2 phosphoribosylamine--glycine ligase compare
Psest_2437 -2.1 -6.8 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) compare
Psest_2447 -2.0 -2.8 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_3129 -2.0 -1.8 tyrosine recombinase XerD compare
Psest_1660 -1.9 -3.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_1661 -1.8 -2.3 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_3123 -1.8 -2.0 dihydroorotase, homodimeric type compare
Psest_0359 -1.7 -4.5 Transcriptional regulators compare
Psest_0442 -1.7 -2.6 ATPases of the AAA+ class compare
Psest_3226 -1.7 -1.7 Predicted membrane protein compare
Psest_3810 -1.7 -1.6 orotate phosphoribosyltransferase compare
Psest_2436 -1.7 -5.1 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) (from data) conserved
Psest_0193 -1.6 -1.6 conserved hypothetical protein compare
Psest_1082 -1.6 -3.1 Enoyl-CoA hydratase/carnithine racemase compare
Psest_1496 -1.6 -1.5 Holliday junction DNA helicase, RuvA subunit compare
Psest_4191 -1.6 -3.6 Transcriptional regulator compare
Psest_0498 -1.5 -1.8 ribosome small subunit-dependent GTPase A compare
Psest_1655 -1.5 -4.7 NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit compare
Psest_3546 -1.4 -2.0 Phosphatidylglycerophosphatase A and related proteins compare
Psest_0845 -1.4 -1.6 hypothetical protein compare
Psest_1765 -1.4 -6.3 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_2532 -1.4 -3.1 Uncharacterized protein conserved in bacteria compare
Psest_1659 -1.4 -2.9 NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit compare
Psest_3395 -1.4 -1.2 hypothetical protein compare
Psest_1947 -1.3 -0.9 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_1079 -1.3 -5.0 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_2104 -1.3 -2.1 IscR-regulated protein YhgI compare
Psest_1277 -1.3 -8.8 2-isopropylmalate synthase, yeast type compare
Psest_3960 -1.3 -2.2 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_4083 -1.2 -8.6 Predicted permease compare
Psest_2067 -1.2 -1.9 ABC-type oligopeptide transport system, periplasmic component compare
Psest_0725 -1.2 -2.5 Negative regulator of beta-lactamase expression compare
Psest_2325 -1.2 -8.1 alpha-L-glutamate ligase-related protein compare
Psest_4219 -1.2 -2.2 DNA polymerase I compare
Psest_4012 -1.1 -7.6 TRAP-type mannitol/chloroaromatic compound transport system, small permease component compare
Psest_2324 -1.1 -9.2 hypothetical protein compare
Psest_0170 -1.1 -4.9 5,10-methenyltetrahydrofolate synthetase compare
Psest_1306 -1.1 -2.2 hypothetical protein compare
Psest_1008 -1.1 -1.5 hypothetical protein compare
Psest_2864 -1.1 -4.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_4044 -1.1 -3.2 type I site-specific deoxyribonuclease, HsdR family compare
Psest_1000 -1.1 -6.0 PAS domain S-box compare
Psest_2719 -1.1 -1.8 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_4013 -1.0 -4.9 TRAP transporter, DctM subunit compare
Psest_1695 -1.0 -3.4 Tfp pilus assembly protein PilZ compare
Psest_2944 -1.0 -1.1 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_3456 -1.0 -2.1 RNA polymerase sigma factor, sigma-70 family compare
Psest_3322 -1.0 -8.2 TIGR02099 family protein compare
Psest_1884 -1.0 -2.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0119 -1.0 -2.0 hypothetical protein compare
Psest_0191 -1.0 -0.9 PAS domain S-box compare
Psest_0740 -0.9 -2.0 Transcriptional regulator compare
Psest_1083 -0.9 -5.9 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) compare
Psest_3338 -0.9 -1.7 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_1080 -0.9 -5.7 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Psest_3767 -0.9 -3.0 tyrosine recombinase XerC compare
Psest_0537 -0.9 -1.7 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_0212 -0.9 -1.7 exodeoxyribonuclease V, gamma subunit compare
Psest_0851 -0.9 -6.4 Transcriptional regulators compare
Psest_1762 -0.9 -2.0 cytochrome c-type biogenesis protein CcmI compare
Psest_2500 -0.9 -2.5 hypothetical protein compare
Psest_2322 -0.9 -1.9 Transcriptional regulators compare
Psest_3700 -0.9 -1.4 hypothetical protein compare
Psest_2123 -0.9 -1.9 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_2323 -0.9 -6.4 Uncharacterized protein conserved in archaea compare
Psest_2321 -0.9 -2.7 methylisocitrate lyase compare
Psest_2906 -0.8 -2.3 tRNA_Thr_CGT compare
Psest_1144 -0.8 -1.5 AmpG-related permease compare
Psest_0417 -0.8 -2.0 Acyl-CoA dehydrogenases compare
Psest_0257 -0.8 -1.2 Predicted Zn-dependent peptidases compare
Psest_3247 -0.8 -1.7 Uncharacterized membrane protein compare
Psest_3296 -0.8 -1.1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_3766 -0.8 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_3806 -0.8 -5.1 Phosphomannomutase compare
Psest_3809 -0.8 -3.5 hypothetical protein compare
Psest_3146 -0.8 -1.7 hypothetical protein compare
Psest_1528 -0.8 -3.3 Acetyltransferases, including N-acetylases of ribosomal proteins compare
Psest_0300 -0.8 -5.0 Methyl-accepting chemotaxis protein compare
Psest_3860 -0.8 -1.9 Predicted permeases compare
Psest_2946 -0.8 -1.9 septum site-determining protein MinD compare
Psest_3565 -0.8 -1.1 hypothetical protein compare
Psest_4371 -0.8 -1.6 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_1242 -0.8 -1.5 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_1295 -0.8 -3.7 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0491 -0.8 -5.7 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_3289 -0.8 -4.7 prepilin-type N-terminal cleavage/methylation domain compare
Psest_0660 -0.7 -1.7 Methyl-accepting chemotaxis protein compare
Psest_0175 -0.7 -4.0 Xaa-Pro aminopeptidase compare
Psest_0575 -0.7 -1.0 HrpA-like helicases compare
Psest_3305 -0.7 -3.9 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_0277 -0.7 -0.9 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_3383 -0.7 -2.7 Uncharacterized protein conserved in bacteria compare
Psest_4170 -0.7 -1.4 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_1527 -0.7 -5.2 Na+/proline symporter compare
Psest_2806 -0.7 -3.8 RNA polymerase sigma factor RpoS compare
Psest_3288 -0.7 -5.3 type IV-A pilus assembly ATPase PilB compare
Psest_4088 -0.7 -2.8 Transcriptional regulators compare
Psest_2645 -0.7 -3.7 Transcriptional regulator compare
Psest_1115 -0.7 -1.6 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_1065 -0.7 -0.9 hypothetical protein compare
Psest_0520 -0.7 -0.8 hypothetical protein compare
Psest_2613 -0.7 -1.3 hypothetical protein compare
Psest_0285 -0.6 -4.3 pilus retraction protein PilT compare
Psest_3716 -0.6 -5.0 Tfp pilus assembly protein PilP compare
Psest_3664 -0.6 -0.8 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_2027 -0.6 -4.2 ATP-dependent Clp protease ATP-binding subunit clpA compare
Psest_0722 -0.6 -3.3 Predicted ATPase compare
Psest_0346 -0.6 -1.1 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_3718 -0.6 -2.9 Tfp pilus assembly protein PilN compare
Psest_2643 -0.6 -1.4 Beta-glucosidase-related glycosidases compare
Psest_1860 -0.6 -2.4 Uncharacterized conserved protein compare
Psest_0542 -0.6 -4.7 AMP nucleosidase compare
Psest_2329 -0.6 -5.0 Transcriptional regulator compare
Psest_2304 -0.6 -0.9 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_4085 -0.6 -4.4 Biotin carboxylase compare
Psest_3719 -0.6 -4.7 type IV pilus assembly protein PilM compare
Psest_1084 -0.6 -4.1 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) (from data) compare
Psest_4084 -0.6 -4.8 oxaloacetate decarboxylase alpha subunit compare
Psest_3715 -0.6 -4.9 type IV pilus secretin (or competence protein) PilQ compare
Psest_2122 -0.6 -0.9 Parvulin-like peptidyl-prolyl isomerase compare
Psest_3962 -0.6 -0.9 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_0515 -0.6 -2.2 rare lipoprotein A compare
Psest_2084 -0.6 -2.8 Fructose-2,6-bisphosphatase compare
Psest_2708 -0.6 -3.4 transaldolase compare
Psest_1489 -0.6 -1.4 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_4220 -0.6 -1.5 Protein of unknown function (DUF2782). compare
Psest_1087 -0.6 -1.0 uncharacterized peroxidase-related enzyme compare
Psest_3168 -0.6 -1.5 Molybdopterin converting factor, large subunit compare
Psest_1206 -0.6 -1.7 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_4276 -0.5 -1.2 hypothetical protein compare
Psest_3047 -0.5 -0.7 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_3039 -0.5 -0.9 periplasmic nitrate reductase, NapE protein compare
Psest_0504 -0.5 -2.4 Putative effector of murein hydrolase LrgA compare
Psest_1491 -0.5 -1.5 Cold shock proteins compare
Psest_2698 -0.5 -2.3 benzoate 1,2-dioxygenase, small subunit compare
Psest_3064 -0.5 -1.3 hypothetical protein compare
Psest_4363 -0.5 -3.0 ATPases involved in chromosome partitioning compare
Psest_3435 -0.5 -1.9 hypothetical protein compare
Psest_1993 -0.5 -2.4 Uncharacterized protein conserved in bacteria compare
Psest_1509 -0.5 -2.9 quinolinate synthetase complex, A subunit compare
Psest_2253 -0.5 -1.3 small redox-active disulfide protein 2 compare
Psest_0861 -0.5 -2.6 hypothetical protein compare
Psest_1204 -0.5 -1.5 Transcriptional regulators compare
Psest_1075 -0.5 -2.3 Predicted transcriptional regulators compare
Psest_2940 -0.5 -1.5 Predicted membrane protein compare
Psest_1473 -0.5 -2.7 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source L-Isoleucine in Pseudomonas stutzeri RCH2

For carbon source L-Isoleucine across organisms