Experiment set12H12 for Pseudomonas stutzeri RCH2

Compare to:

L-Proline carbon source

200 most important genes:

  gene name fitness t score description  
Psest_0279 -7.1 -4.9 methionine biosynthesis protein MetW compare
Psest_3647 -6.8 -6.6 Indole-3-glycerol phosphate synthase compare
Psest_3944 -6.7 -6.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_3866 -6.5 -15.2 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3650 -6.4 -12.9 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0280 -6.3 -14.7 homoserine O-acetyltransferase compare
Psest_2578 -6.2 -13.3 O-succinylhomoserine sulfhydrylase compare
Psest_0325 -5.9 -12.0 Putative threonine efflux protein compare
Psest_2590 -5.8 -2.2 3-isopropylmalate dehydratase, small subunit compare
Psest_0155 -5.6 -7.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_0063 -5.6 -14.0 tryptophan synthase, beta subunit compare
Psest_3226 -5.5 -2.1 Predicted membrane protein compare
Psest_3299 -5.5 -15.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_2584 -5.5 -6.5 Phosphoribosylanthranilate isomerase compare
Psest_0062 -5.5 -13.7 tryptophan synthase, alpha subunit compare
Psest_3648 -5.4 -11.0 anthranilate phosphoribosyltransferase compare
Psest_0153 -5.2 -16.4 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0152 -5.2 -6.6 Imidazoleglycerol-phosphate dehydratase compare
Psest_3864 -4.9 -18.4 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_2591 -4.8 -5.7 3-isopropylmalate dehydratase, large subunit compare
Psest_2589 -4.8 -15.5 3-isopropylmalate dehydrogenase compare
Psest_3298 -4.8 -15.2 histidinol dehydrogenase compare
Psest_0313 -4.7 -8.9 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_0687 -4.6 -12.0 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_1037 -4.2 -3.3 acetolactate synthase, small subunit compare
Psest_3943 -4.1 -5.7 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0326 -3.7 -11.3 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_1295 -3.7 -8.1 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3721 -3.6 -9.6 Malic enzyme compare
Psest_2579 -3.5 -3.4 amidophosphoribosyltransferase compare
Psest_1772 -3.4 -6.5 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3080 -3.4 -4.3 AraC-type DNA-binding domain-containing proteins compare
Psest_1686 -3.3 -7.4 fatty acid/phospholipid synthesis protein PlsX compare
Psest_4191 -3.2 -5.2 Transcriptional regulator compare
Psest_2945 -3.1 -2.1 septum site-determining protein MinC compare
Psest_3862 -3.1 -15.7 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0725 -3.1 -4.2 Negative regulator of beta-lactamase expression compare
Psest_1473 -2.9 -7.1 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0327 -2.9 -5.3 Transcriptional regulator compare
Psest_3079 -2.8 -13.1 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) (from data) conserved
Psest_2968 -2.8 -11.6 flagellar basal-body rod protein FlgB compare
Psest_2967 -2.7 -6.7 flagellar basal-body rod protein FlgC compare
Psest_0411 -2.7 -12.6 biotin synthetase compare
Psest_2312 -2.6 -8.5 Small-conductance mechanosensitive channel compare
Psest_3317 -2.6 -7.1 Phosphotransferase System HPr (HPr) Family compare
Psest_2088 -2.6 -2.7 Uncharacterized protein conserved in bacteria compare
Psest_2651 -2.4 -6.1 DNA topoisomerase I, bacterial compare
Psest_1474 -2.2 -1.5 phosphoribosylaminoimidazole synthetase compare
Psest_3304 -2.2 -6.0 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_0771 -2.2 -11.4 Acyl-CoA hydrolase compare
Psest_3720 -2.2 -15.5 penicillin-binding protein, 1A family compare
Psest_0306 -2.1 -14.0 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_0514 -2.1 -9.4 lytic murein transglycosylase B compare
Psest_3159 -2.1 -6.5 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0999 -2.1 -2.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0412 -2.0 -10.4 8-amino-7-oxononanoate synthase compare
Psest_1765 -1.9 -8.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0415 -1.9 -4.8 dethiobiotin synthase compare
Psest_3377 -1.9 -1.8 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_3810 -1.9 -1.3 orotate phosphoribosyltransferase compare
Psest_1013 -1.9 -3.0 phosphoribosylamine--glycine ligase compare
Psest_1486 -1.8 -3.8 hypothetical protein compare
Psest_2959 -1.8 -13.7 flagellar hook-associated protein FlgK compare
Psest_2712 -1.8 -5.4 Surface lipoprotein compare
Psest_3732 -1.7 -7.3 polyphosphate kinase 1 compare
Psest_3305 -1.7 -8.1 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_2973 -1.7 -7.3 Flagellar biosynthesis/type III secretory pathway chaperone compare
Psest_2961 -1.7 -4.1 Flagellar basal-body P-ring protein compare
Psest_3768 -1.7 -6.7 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Psest_2971 -1.7 -7.3 flagella basal body P-ring formation protein FlgA compare
Psest_1054 -1.7 -8.1 Diaminopimelate decarboxylase compare
Psest_3307 -1.7 -6.2 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_0138 -1.7 -9.3 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_3129 -1.7 -1.5 tyrosine recombinase XerD compare
Psest_0413 -1.7 -5.8 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_1282 -1.7 -2.3 Amidases related to nicotinamidase compare
Psest_4075 -1.7 -12.2 symporter for L-glutamate, L-glutamine, and L-proline (from data) compare
Psest_0442 -1.7 -2.5 ATPases of the AAA+ class compare
Psest_2964 -1.7 -7.6 flagellar basal-body rod protein FlgF compare
Psest_2960 -1.6 -9.3 flagellar rod assembly protein/muramidase FlgJ compare
Psest_0496 -1.6 -7.1 flagellar motor stator protein MotA compare
Psest_2037 -1.6 -6.3 uroporphyrin-III C-methyltransferase compare
Psest_0139 -1.6 -4.3 ABC-type histidine transport system, ATPase component compare
Psest_2946 -1.6 -3.7 septum site-determining protein MinD compare
Psest_3306 -1.6 -5.0 conserved hypothetical integral membrane protein compare
Psest_0511 -1.6 -1.7 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_2090 -1.6 -2.9 Protein of unknown function (DUF2970). compare
Psest_2958 -1.6 -11.2 flagellar hook-associated protein 3 compare
Psest_1729 -1.5 -5.4 flagellar motor switch protein FliM compare
Psest_0277 -1.5 -1.7 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_4077 -1.5 -10.7 amino acid carrier protein compare
Psest_2507 -1.5 -10.7 Flagellin and related hook-associated proteins compare
Psest_0197 -1.5 -11.2 TRAP transporter, 4TM/12TM fusion protein compare
Psest_3993 -1.5 -8.6 alpha-L-glutamate ligases, RimK family compare
Psest_0497 -1.5 -7.9 Flagellar motor protein compare
Psest_1723 -1.5 -7.5 flagellar export protein FliJ compare
Psest_0137 -1.5 -8.7 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_3303 -1.5 -5.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1735 -1.5 -9.0 flagellar biosynthetic protein FlhB compare
Psest_1734 -1.5 -5.5 flagellar biosynthetic protein FliR compare
Psest_2944 -1.5 -1.4 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_0136 -1.5 -9.7 amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family compare
Psest_3351 -1.4 -5.3 peptide chain release factor 3 compare
Psest_1489 -1.4 -4.1 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_2963 -1.4 -6.8 flagellar basal-body rod protein FlgG, Gram-negative bacteria compare
Psest_2962 -1.4 -8.1 Flagellar basal body L-ring protein compare
Psest_0292 -1.4 -3.0 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_2965 -1.4 -11.5 fagellar hook-basal body proteins compare
Psest_1724 -1.4 -3.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1740 -1.4 -7.2 RNA polymerase sigma factor, FliA/WhiG family compare
Psest_1719 -1.3 -6.8 flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) compare
Psest_2585 -1.3 -1.1 pseudouridylate synthase I compare
Psest_0414 -1.3 -4.1 biotin biosynthesis protein BioC compare
Psest_1732 -1.3 -5.5 flagellar biosynthetic protein FliP compare
Psest_0489 -1.3 -1.9 phosphoserine phosphatase SerB compare
Psest_1058 -1.3 -3.1 ribosomal-protein-alanine acetyltransferase compare
Psest_2966 -1.3 -6.1 Flagellar hook capping protein compare
Psest_0198 -1.3 -7.6 TRAP transporter solute receptor, TAXI family compare
Psest_1720 -1.3 -8.2 flagellar motor switch protein FliG compare
Psest_1722 -1.2 -9.5 flagellar protein export ATPase FliI compare
Psest_0449 -1.2 -8.6 Glutamine synthetase adenylyltransferase compare
Psest_0709 -1.2 -6.8 pseudouridine synthase, RluA family compare
Psest_1746 -1.2 -7.6 Flagellar motor protein compare
Psest_1957 -1.2 -8.5 outer membrane porin, OprD family. compare
Psest_1994 -1.2 -4.0 Amidases related to nicotinamidase compare
Psest_1940 -1.2 -4.6 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain compare
Psest_1947 -1.2 -0.8 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_1737 -1.2 -5.2 flagellar biosynthesis protein FlhA compare
Psest_3289 -1.2 -6.3 prepilin-type N-terminal cleavage/methylation domain compare
Psest_1718 -1.1 -3.9 flagellar hook-basal body complex protein FliE compare
Psest_0969 -1.1 -1.6 transcription elongation factor GreA compare
Psest_1721 -1.1 -2.9 Flagellar biosynthesis/type III secretory pathway protein compare
Psest_2786 -1.1 -1.4 Domain of unknown function (DUF3597). compare
Psest_1804 -1.1 -1.6 Superfamily II DNA and RNA helicases compare
Psest_3122 -1.1 -4.6 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_3998 -1.1 -5.7 glutamate--cysteine ligase compare
Psest_2333 -1.1 -1.2 Protein of unknown function (DUF3359). compare
Psest_1741 -1.1 -2.5 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3872 -1.1 -6.0 FAD/FMN-containing dehydrogenases compare
Psest_0722 -1.1 -4.8 Predicted ATPase compare
Psest_0520 -1.1 -1.1 hypothetical protein compare
Psest_1939 -1.1 -6.7 Tetratricopeptide repeat. compare
Psest_1514 -1.1 -3.6 Glycine cleavage system regulatory protein compare
Psest_0715 -1.1 -8.0 NADH dehydrogenase, FAD-containing subunit conserved
Psest_3301 -1.1 -1.8 Predicted transcriptional regulator, BolA superfamily compare
Psest_3078 -1.1 -6.7 L-proline:Na+ symporter (from data) compare
Psest_2506 -1.1 -3.9 Uncharacterized flagellar protein FlaG compare
Psest_1144 -1.0 -1.4 AmpG-related permease compare
Psest_3531 -1.0 -1.1 Peptidase propeptide and YPEB domain. compare
Psest_3818 -1.0 -4.7 endoribonuclease L-PSP, putative compare
Psest_1728 -1.0 -5.1 Flagellar basal body-associated protein compare
Psest_3228 -1.0 -6.0 Zn-dependent protease with chaperone function compare
Psest_0716 -1.0 -2.6 Protein of unknown function (DUF3094). compare
Psest_3406 -1.0 -7.0 Restriction endonuclease S subunits compare
Psest_1733 -1.0 -1.2 flagellar biosynthetic protein FliQ compare
Psest_3270 -1.0 -2.2 probable S-adenosylmethionine-dependent methyltransferase, YraL family compare
Psest_1194 -1.0 -5.1 Kef-type K+ transport system, predicted NAD-binding component compare
Psest_2643 -1.0 -1.9 Beta-glucosidase-related glycosidases compare
Psest_1704 -1.0 -1.4 Dehydrogenases (flavoproteins) compare
Psest_1516 -1.0 -2.8 Uncharacterized lipoprotein compare
Psest_1824 -1.0 -2.2 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_1942 -1.0 -5.9 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Psest_3649 -1.0 -4.2 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_1217 -0.9 -5.5 Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein compare
Psest_3933 -0.9 -5.7 hypothetical protein compare
Psest_1640 -0.9 -6.9 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_1293 -0.9 -1.2 VanZ like family. compare
Psest_0334 -0.9 -2.4 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3546 -0.9 -1.1 Phosphatidylglycerophosphatase A and related proteins compare
Psest_4298 -0.9 -1.1 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_2719 -0.9 -1.5 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_0485 -0.9 -2.7 clan AA aspartic protease, TIGR02281 family compare
Psest_3860 -0.9 -2.4 Predicted permeases compare
Psest_0466 -0.9 -2.6 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1055 -0.9 -5.8 Saccharopine dehydrogenase and related proteins compare
Psest_4178 -0.8 -2.2 hypothetical protein compare
Psest_1142 -0.8 -3.0 Uncharacterized protein conserved in bacteria compare
Psest_0285 -0.8 -6.0 pilus retraction protein PilT compare
Psest_4088 -0.8 -2.9 Transcriptional regulators compare
Psest_0417 -0.8 -2.0 Acyl-CoA dehydrogenases compare
Psest_0867 -0.8 -1.2 hypothetical protein compare
Psest_2083 -0.8 -3.7 Putative sterol carrier protein compare
Psest_1868 -0.8 -3.7 yecA family protein compare
Psest_1938 -0.8 -4.6 hypothetical protein compare
Psest_2001 -0.8 -1.1 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_4095 -0.8 -2.2 Uncharacterized protein conserved in bacteria compare
Psest_2768 -0.8 -1.6 Kef-type K+ transport systems, predicted NAD-binding component compare
Psest_2322 -0.8 -1.9 Transcriptional regulators compare
Psest_0276 -0.8 -3.1 putative oxygen-independent coproporphyrinogen III oxidase compare
Psest_1472 -0.8 -4.9 Protein of unknown function (DUF3108). compare
Psest_3853 -0.8 -1.4 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_1000 -0.8 -5.3 PAS domain S-box compare
Psest_0499 -0.8 -3.6 hypothetical protein compare
Psest_0831 -0.8 -1.1 hypothetical protein compare
Psest_0031 -0.8 -1.3 Uncharacterized conserved protein compare
Psest_1986 -0.7 -1.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_0445 -0.7 -5.6 PAS domain S-box/diguanylate cyclase (GGDEF) domain compare
Psest_0457 -0.7 -2.8 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_3372 -0.7 -5.3 Tfp pilus assembly protein PilW compare
Psest_0655 -0.7 -1.6 Chemotaxis signal transduction protein compare


Specific Phenotypes

For 12 genes in this experiment

For carbon source L-Proline in Pseudomonas stutzeri RCH2

For carbon source L-Proline across organisms