| Pathway | #Steps | #Present | #Specific |
|---|
| L-serine degradation | 3 | 3 | 3 |
| L-malate degradation II | 1 | 1 | 1 |
| L-asparagine degradation I | 1 | 1 | 1 |
| D-serine degradation | 3 | 3 | 2 |
| L-tryptophan degradation II (via pyruvate) | 3 | 2 | 2 |
| L-cysteine degradation II | 3 | 2 | 2 |
| malate/L-aspartate shuttle pathway | 2 | 2 | 1 |
| ethylene glycol degradation | 2 | 2 | 1 |
| 2-O-α-mannosyl-D-glycerate degradation | 2 | 1 | 1 |
| putrescine degradation I | 2 | 1 | 1 |
| phenylethylamine degradation I | 2 | 1 | 1 |
| phenylethanol degradation | 2 | 1 | 1 |
| proline to cytochrome bo oxidase electron transfer | 2 | 1 | 1 |
| phenylethylamine degradation II | 2 | 1 | 1 |
| putrescine degradation V | 2 | 1 | 1 |
| glycine betaine degradation III | 7 | 4 | 3 |
| L-histidine degradation II | 5 | 5 | 2 |
| felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis | 5 | 2 | 2 |
| glycine betaine degradation I | 8 | 4 | 3 |
| glycine degradation | 3 | 3 | 1 |
| ethanol degradation II | 3 | 3 | 1 |
| ethanol degradation IV | 3 | 3 | 1 |
| TCA cycle VIII (Chlamydia) | 6 | 5 | 2 |
| L-methionine biosynthesis II | 6 | 5 | 2 |
| L-phenylalanine degradation II (anaerobic) | 3 | 2 | 1 |
| ethanol degradation III | 3 | 2 | 1 |
| hypotaurine degradation | 3 | 2 | 1 |
| L-asparagine degradation III (mammalian) | 3 | 2 | 1 |
| putrescine degradation IV | 3 | 2 | 1 |
| L-proline degradation I | 3 | 2 | 1 |
| styrene degradation | 3 | 1 | 1 |
| L-carnitine degradation II | 3 | 1 | 1 |
| L-arginine degradation I (arginase pathway) | 3 | 1 | 1 |
| histamine degradation | 3 | 1 | 1 |
| superpathway of glycol metabolism and degradation | 7 | 6 | 2 |
| incomplete reductive TCA cycle | 7 | 3 | 2 |
| pyruvate fermentation to propanoate I | 7 | 2 | 2 |
| D-galactarate degradation I | 4 | 4 | 1 |
| superpathway of L-aspartate and L-asparagine biosynthesis | 4 | 4 | 1 |
| L-histidine degradation I | 4 | 4 | 1 |
| D-glucarate degradation I | 4 | 4 | 1 |
| chitin deacetylation | 4 | 3 | 1 |
| phytol degradation | 4 | 3 | 1 |
| glycolate and glyoxylate degradation I | 4 | 3 | 1 |
| L-mimosine degradation | 8 | 4 | 2 |
| putrescine degradation III | 4 | 2 | 1 |
| fatty acid α-oxidation I (plants) | 4 | 2 | 1 |
| glutathione-mediated detoxification I | 8 | 3 | 2 |
| photosynthesis light reactions | 4 | 1 | 1 |
| ethene biosynthesis II (microbes) | 4 | 1 | 1 |
| L-tryptophan degradation X (mammalian, via tryptamine) | 4 | 1 | 1 |
| D-arabinose degradation II | 4 | 1 | 1 |
| NADPH to cytochrome c oxidase via plastocyanin (thylakoid membrane) | 4 | 1 | 1 |
| gluconeogenesis I | 13 | 12 | 3 |
| TCA cycle II (plants and fungi) | 9 | 7 | 2 |
| TCA cycle V (2-oxoglutarate synthase) | 9 | 7 | 2 |
| TCA cycle IV (2-oxoglutarate decarboxylase) | 9 | 6 | 2 |
| Entner-Doudoroff pathway II (non-phosphorylative) | 9 | 6 | 2 |
| superpathway of D-glucarate and D-galactarate degradation | 5 | 5 | 1 |
| L-arginine degradation II (AST pathway) | 5 | 5 | 1 |
| TCA cycle I (prokaryotic) | 10 | 9 | 2 |
| TCA cycle III (animals) | 10 | 8 | 2 |
| mitochondrial NADPH production (yeast) | 5 | 3 | 1 |
| anaerobic energy metabolism (invertebrates, mitochondrial) | 10 | 5 | 2 |
| sphingosine and sphingosine-1-phosphate metabolism | 10 | 4 | 2 |
| N-(1-deoxy-D-fructos-1-yl)-L-asparagine degradation | 5 | 2 | 1 |
| octane oxidation | 5 | 2 | 1 |
| dopamine degradation | 5 | 1 | 1 |
| C4 photosynthetic carbon assimilation cycle, NAD-ME type | 11 | 8 | 2 |
| reductive TCA cycle I | 11 | 6 | 2 |
| L-glutamate degradation VIII (to propanoate) | 11 | 2 | 2 |
| superpathway of anaerobic energy metabolism (invertebrates) | 17 | 10 | 3 |
| glyoxylate cycle | 6 | 6 | 1 |
| superpathway of glyoxylate bypass and TCA | 12 | 11 | 2 |
| L-histidine degradation III | 6 | 4 | 1 |
| 3-methyl-branched fatty acid α-oxidation | 6 | 3 | 1 |
| reductive TCA cycle II | 12 | 5 | 2 |
| superpathway of photosynthetic hydrogen production | 6 | 2 | 1 |
| methylgallate degradation | 6 | 2 | 1 |
| alkane oxidation | 6 | 1 | 1 |
| formaldehyde assimilation I (serine pathway) | 13 | 8 | 2 |
| (S)-lactate fermentation to propanoate, acetate and hydrogen | 13 | 5 | 2 |
| noradrenaline and adrenaline degradation | 13 | 4 | 2 |
| superpathway of glyoxylate cycle and fatty acid degradation | 14 | 11 | 2 |
| anaerobic energy metabolism (invertebrates, cytosol) | 7 | 5 | 1 |
| serotonin degradation | 7 | 3 | 1 |
| ceramide degradation by α-oxidation | 7 | 2 | 1 |
| limonene degradation IV (anaerobic) | 7 | 1 | 1 |
| superpathway of L-lysine, L-threonine and L-methionine biosynthesis II | 15 | 13 | 2 |
| mixed acid fermentation | 16 | 14 | 2 |
| L-histidine degradation VI | 8 | 7 | 1 |
| partial TCA cycle (obligate autotrophs) | 8 | 7 | 1 |
| superpathway of ornithine degradation | 8 | 6 | 1 |
| purine nucleobases degradation II (anaerobic) | 24 | 16 | 3 |
| superpathway of NAD/NADP - NADH/NADPH interconversion (yeast) | 8 | 5 | 1 |
| 2-deoxy-D-ribose degradation II | 8 | 3 | 1 |
| protocatechuate degradation I (meta-cleavage pathway) | 8 | 3 | 1 |
| ceramide and sphingolipid recycling and degradation (yeast) | 16 | 4 | 2 |
| aromatic biogenic amine degradation (bacteria) | 8 | 1 | 1 |
| superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | 26 | 25 | 3 |
| TCA cycle VI (Helicobacter) | 9 | 6 | 1 |
| TCA cycle VII (acetate-producers) | 9 | 6 | 1 |
| photorespiration I | 9 | 5 | 1 |
| photorespiration III | 9 | 5 | 1 |
| L-phenylalanine degradation IV (mammalian, via side chain) | 9 | 4 | 1 |
| methylaspartate cycle | 19 | 9 | 2 |
| glycolysis V (Pyrococcus) | 10 | 7 | 1 |
| photorespiration II | 10 | 6 | 1 |
| superpathway of vanillin and vanillate degradation | 10 | 3 | 1 |
| glycolysis II (from fructose 6-phosphate) | 11 | 11 | 1 |
| superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle | 22 | 18 | 2 |
| superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation | 11 | 8 | 1 |
| superpathway of phenylethylamine degradation | 11 | 4 | 1 |
| gluconeogenesis III | 12 | 9 | 1 |
| syringate degradation | 12 | 3 | 1 |
| glycolysis I (from glucose 6-phosphate) | 13 | 13 | 1 |
| superpathway of L-arginine and L-ornithine degradation | 13 | 10 | 1 |
| superpathway of glycolysis and the Entner-Doudoroff pathway | 17 | 16 | 1 |
| oxygenic photosynthesis | 17 | 11 | 1 |
| superpathway of hexitol degradation (bacteria) | 18 | 16 | 1 |
| gluconeogenesis II (Methanobacterium thermoautotrophicum) | 18 | 8 | 1 |
| Methanobacterium thermoautotrophicum biosynthetic metabolism | 56 | 21 | 3 |
| hexitol fermentation to lactate, formate, ethanol and acetate | 19 | 17 | 1 |
| superpathway of anaerobic sucrose degradation | 19 | 17 | 1 |
| superpathway of N-acetylneuraminate degradation | 22 | 18 | 1 |
| ethene biosynthesis V (engineered) | 25 | 18 | 1 |
| photosynthetic 3-hydroxybutanoate biosynthesis (engineered) | 26 | 19 | 1 |
| 1-butanol autotrophic biosynthesis (engineered) | 27 | 19 | 1 |
| anaerobic aromatic compound degradation (Thauera aromatica) | 27 | 3 | 1 |
| superpathway of microbial D-galacturonate and D-glucuronate degradation | 31 | 19 | 1 |
| superpathway of pentose and pentitol degradation | 42 | 12 | 1 |