Experiment set11S273 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS00125		-4.5	-1.7	DUF2798 domain-containing protein
MMP_RS07350		-4.0	-2.6	preprotein translocase subunit Sec61beta
MMP_RS02805		-3.9	-1.5	HEPN domain-containing protein
MMP_RS03960		-3.3	-1.2	hypothetical protein
MMP_RS07845		-3.3	-2.3	LL-diaminopimelate aminotransferase
MMP_RS01420		-3.3	-1.7	hypothetical protein
MMP_RS01020		-3.3	-1.2	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS03445		-3.0	-1.1	methanogenesis marker 17 protein
MMP_RS05550		-2.7	-1.0	cation:proton antiporter
MMP_RS08675		-2.6	-1.8	class III signal peptide-containing protein
MMP_RS02175		-2.5	-0.9	DUF1611 domain-containing protein
MMP_RS01195		-2.5	-1.3	metalloregulator ArsR/SmtB family transcription factor
MMP_RS00520		-2.5	-1.5	RNA polymerase Rpb4 family protein
MMP_RS07555		-2.4	-0.9	monovalent cation/H+ antiporter subunit E
MMP_RS06900		-2.3	-2.2	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS05835		-2.2	-0.8	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS01335		-2.1	-1.6	prefoldin subunit beta
MMP_RS06730		-2.0	-1.4	phosphopantothenate/pantothenate synthetase
MMP_RS03205		-2.0	-1.0	peptidyl-tRNA hydrolase Pth2
MMP_RS00080		-1.9	-3.3	RecB-family nuclease
MMP_RS08210		-1.8	-1.6	phosphatidylglycerophosphatase A
MMP_RS01325		-1.8	-1.2	dihydroneopterin aldolase family protein
MMP_RS02195		-1.8	-2.4	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS03300		-1.7	-0.6	TOBE domain-containing protein
MMP_RS02045		-1.7	-1.1	tRNA-Met
MMP_RS01795		-1.6	-1.0	methanogenesis marker 6 protein
MMP_RS02900		-1.6	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS01790		-1.6	-3.8	restriction endonuclease
MMP_RS05920		-1.6	-0.6	50S ribosomal protein L37e
MMP_RS07545		-1.6	-0.8	HTH domain-containing protein
MMP_RS05555		-1.5	-1.0	DUF4040 domain-containing protein
MMP_RS02490		-1.5	-1.4	hypothetical protein
MMP_RS00750		-1.5	-1.5	fumarate hydratase
MMP_RS05965		-1.5	-1.5	carboxymuconolactone decarboxylase family protein
MMP_RS03385		-1.5	-0.8	cation diffusion facilitator family transporter
MMP_RS01660		-1.5	-1.5	hypothetical protein
MMP_RS00395		-1.5	-1.1	MGMT family protein
MMP_RS05845		-1.4	-1.0	tRNA-intron lyase
MMP_RS00515		-1.4	-0.7	DUF655 domain-containing protein
MMP_RS01700		-1.4	-0.7	dihydroxy-acid dehydratase
MMP_RS03485		-1.4	-1.8	TIGR00267 family protein
MMP_RS08415		-1.4	-1.3	radical SAM protein
MMP_RS05720		-1.3	-1.9	signal recognition particle subunit SRP19/SEC65 family protein
MMP_RS02940		-1.3	-3.8	TatD family hydrolase
MMP_RS08435		-1.3	-1.0	Era-like GTP-binding protein
MMP_RS00430		-1.3	-2.2	hypothetical protein
MMP_RS06350		-1.2	-1.9	HesA/MoeB/ThiF family protein
MMP_RS06485		-1.2	-0.6	zinc ribbon domain-containing protein
MMP_RS07645		-1.2	-3.1	aldehyde dehydrogenase family protein
MMP_RS05815		-1.2	-0.7	NOL1/NOP2/sun family putative RNA methylase
MMP_RS06630		-1.2	-0.6	UPF0058 family protein
MMP_RS01270		-1.2	-5.1	prepilin peptidase
MMP_RS04305		-1.1	-1.3	hypothetical protein
MMP_RS01830		-1.1	-0.8	tRNA-Val
MMP_RS00250		-1.1	-6.4	Flp pilus assembly complex ATPase component TadA
MMP_RS02800		-1.1	-3.1	nucleotidyltransferase domain-containing protein
MMP_RS05425		-1.1	-1.6	monovalent cation/H+ antiporter complex subunit F
MMP_RS00695		-1.1	-0.6	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS01745		-1.1	-2.7	AMP phosphorylase
MMP_RS00900		-1.1	-0.9	50S ribosomal protein L39e
MMP_RS04015		-1.1	-1.4	hypothetical protein
MMP_RS04710		-1.1	-1.0	hypothetical protein
MMP_RS08750		-1.0	-1.3	hypothetical protein
MMP_RS07755		-1.0	-0.7	DUF555 domain-containing protein
MMP_RS00730		-1.0	-1.8	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06760		-1.0	-1.7	hypothetical protein
MMP_RS06340		-1.0	-2.9	phosphoadenosine phosphosulfate reductase family protein
MMP_RS03550		-1.0	-1.1	DUF2124 domain-containing protein
MMP_RS03095		-1.0	-1.9	diphthine synthase
MMP_RS05460		-1.0	-3.1	YcaO-related McrA-glycine thioamidation protein
MMP_RS02355		-1.0	-1.0	30S ribosomal protein S27ae
MMP_RS06355		-0.9	-1.0	molybdenum cofactor biosynthesis protein MoaE
MMP_RS02700		-0.9	-2.0	formylmethanofuran dehydrogenase subunit C
MMP_RS00325		-0.9	-0.7	RNA-binding protein
MMP_RS06655		-0.9	-4.0	glycoside hydrolase family 15 protein
MMP_RS08310		-0.9	-0.8	TMEM165/GDT1 family protein
MMP_RS06915		-0.9	-2.5	metallophosphoesterase
MMP_RS06585		-0.9	-0.8	DMT family protein
MMP_RS06055		-0.9	-1.7	peroxiredoxin
MMP_RS01310		-0.9	-4.4	hypothetical protein
MMP_RS02735		-0.9	-2.1	MBL fold metallo-hydrolase
MMP_RS04605		-0.9	-1.6	cobalt ECF transporter T component CbiQ
MMP_RS01265		-0.9	-1.1	hypothetical protein
MMP_RS06745		-0.9	-1.3	DUF2119 domain-containing protein
MMP_RS02915		-0.9	-1.4	amino acid ABC transporter permease
MMP_RS05770		-0.9	-2.6	YkgJ family cysteine cluster protein
MMP_RS05950		-0.9	-2.6	nickel-dependent hydrogenase large subunit
MMP_RS01165		-0.9	-1.8	DUF434 domain-containing protein
MMP_RS06430		-0.8	-2.2	6-carboxytetrahydropterin synthase QueD
MMP_RS07635		-0.8	-2.4	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01280		-0.8	-4.4	DUF515 domain-containing protein
MMP_RS00555		-0.8	-3.1	MFS transporter
MMP_RS02480		-0.8	-0.7	hypothetical protein
MMP_RS03145		-0.8	-1.9	fibrillarin-like rRNA/tRNA 2'-O-methyltransferase
MMP_RS06105		-0.8	-1.5	hydrogenase maturation peptidase HycI
MMP_RS01440		-0.8	-2.4	NAAT family transporter
MMP_RS07560		-0.8	-1.1	prefoldin subunit alpha
MMP_RS07750		-0.8	-1.3	DUF357 domain-containing protein
MMP_RS06735		-0.8	-1.8	class I SAM-dependent rRNA methyltransferase
MMP_RS00245		-0.7	-4.5	type II secretion system F family protein
MMP_RS05365		-0.7	-0.8	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH
MMP_RS05895		-0.7	-2.7	metallophosphoesterase
MMP_RS06535		-0.7	-0.9	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS00115		-0.7	-2.5	radical SAM protein
MMP_RS01285		-0.7	-2.4	hypothetical protein
MMP_RS01575		-0.7	-2.0	aldolase
MMP_RS07770		-0.7	-2.5	alanine racemase
MMP_RS01225		-0.7	-1.2	DUF5379 domain-containing protein
MMP_RS01295		-0.7	-3.8	hypothetical protein
MMP_RS03085		-0.7	-2.7	endonuclease III
MMP_RS01315		-0.7	-5.0	DUF2341 domain-containing protein
MMP_RS00240		-0.7	-2.8	type II secretion system F family protein
MMP_RS08720		-0.7	-0.5	4Fe-4S binding protein
MMP_RS02360		-0.7	-2.0	hypothetical protein
MMP_RS02905		-0.7	-1.1	2-thiouracil desulfurase family protein
MMP_RS07900		-0.7	-1.1	YeeE/YedE family protein
MMP_RS04890		-0.7	-0.4	adenylyltransferase/cytidyltransferase family protein
MMP_RS03025		-0.7	-1.2	molybdenum cofactor guanylyltransferase
MMP_RS03235		-0.7	-1.8	tRNA pseudouridine(13) synthase TruD
MMP_RS07620		-0.7	-1.1	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS00640		-0.7	-2.1	ABC transporter substrate-binding protein
MMP_RS05070		-0.7	-2.1	4Fe-4S dicluster domain-containing protein
MMP_RS02100		-0.7	-1.1	metallophosphoesterase
MMP_RS01105		-0.7	-1.5	hypothetical protein
MMP_RS01255		-0.7	-1.2	amino acid ABC transporter ATP-binding protein
MMP_RS00380		-0.6	-1.3	P-II family nitrogen regulator
MMP_RS06445		-0.6	-1.3	DUF89 domain-containing protein
MMP_RS02930		-0.6	-1.0	class I SAM-dependent methyltransferase
MMP_RS03410		-0.6	-2.3	hypothetical protein
MMP_RS09045		-0.6	-2.6	class III signal peptide-containing protein
MMP_RS05310		-0.6	-2.4	hypothetical protein
MMP_RS09055		-0.6	-0.5	CAP domain-containing protein
MMP_RS04990		-0.6	-2.8	aquaporin family protein
MMP_RS06940		-0.6	-0.7	polyprenyl diphosphate synthase
MMP_RS01430		-0.6	-2.3	mechanosensitive ion channel family protein
MMP_RS03625		-0.6	-1.5	cell wall-binding protein
MMP_RS07850		-0.6	-1.2	prephenate dehydratase
MMP_RS03540		-0.6	-1.3	DUF2178 domain-containing protein
MMP_RS02235		-0.6	-2.1	CBS domain-containing protein
MMP_RS03420		-0.6	-1.0	acetolactate synthase small subunit
MMP_RS03785		-0.6	-1.1	cupin domain-containing protein
MMP_RS04195		-0.6	-0.6	flavodoxin
MMP_RS02710		-0.6	-1.9	formylmethanofuran dehydrogenase subunit B
MMP_RS08195		-0.6	-1.6	hypothetical protein
MMP_RS03120		-0.6	-0.9	hypothetical protein
MMP_RS01305		-0.6	-3.4	hypothetical protein
MMP_RS07695		-0.6	-1.2	DUF3236 domain-containing protein
MMP_RS04035		-0.6	-0.6	hypothetical protein
MMP_RS00990		-0.6	-1.0	hypothetical protein
MMP_RS02785		-0.6	-1.7	MarR family transcriptional regulator
MMP_RS08400		-0.6	-0.6	MJ0307 family thioredoxin
MMP_RS04325		-0.6	-2.2	MtaA/CmuA family methyltransferase
MMP_RS02955		-0.6	-0.7	DJ-1/PfpI family protein
MMP_RS06295		-0.6	-1.2	methanogenesis marker 14 protein
MMP_RS08100		-0.6	-1.0	8-amino-7-oxononanoate synthase
MMP_RS00830		-0.6	-0.9	purine phosphoribosyltransferase family protein
MMP_RS07800		-0.6	-1.6	ATP-binding cassette domain-containing protein
MMP_RS01220		-0.6	-1.1	hypothetical protein
MMP_RS01180		-0.6	-0.4	XTP/dITP diphosphatase
MMP_RS04900		-0.6	-3.4	hypothetical protein
MMP_RS02770		-0.6	-1.8	hypothetical protein
MMP_RS07195		-0.6	-1.8	M20 family metallo-hydrolase
MMP_RS00705		-0.6	-0.5	hypothetical protein
MMP_RS02450		-0.6	-1.5	hypothetical protein
MMP_RS01645		-0.6	-0.7	SWIM zinc finger family protein
MMP_RS09025		-0.6	-0.4	hypothetical protein
MMP_RS00960		-0.6	-1.2	iron export ABC transporter permease subunit FetB
MMP_RS08590		-0.6	-1.2	flagellin
MMP_RS04100		-0.6	-1.1	hypothetical protein
MMP_RS03305		-0.6	-1.4	winged helix-turn-helix domain-containing protein
MMP_RS01290		-0.5	-1.8	class III signal peptide-containing protein
MMP_RS05160		-0.5	-2.0	cupredoxin family copper-binding protein
MMP_RS07705		-0.5	-1.5	transcriptional regulator
MMP_RS08855		-0.5	-2.1	hypothetical protein
MMP_RS04630		-0.5	-1.3	3'-5' exonuclease
MMP_RS02500		-0.5	-1.2	minichromosome maintenance protein MCM
MMP_RS01755		-0.5	-0.5	DUF2097 domain-containing protein
MMP_RS01800		-0.5	-0.8	TIGR00303 family protein
MMP_RS04410		-0.5	-1.6	hypothetical protein
MMP_RS04815		-0.5	-1.5	chemotaxis protein CheD
MMP_RS08445		-0.5	-0.7	DUF2099 family protein
MMP_RS01055		-0.5	-0.8	hypothetical protein
MMP_RS04260		-0.5	-1.4	coenzyme F420 hydrogenase subunit gamma
MMP_RS02745		-0.5	-0.8	hypothetical protein
MMP_RS08760		-0.5	-0.5	hypothetical protein
MMP_RS03755		-0.5	-3.0	MarR family transcriptional regulator
MMP_RS02290		-0.5	-1.3	MBL fold metallo-hydrolase
MMP_RS03585		-0.5	-0.9	Hsp20/alpha crystallin family protein
MMP_RS05825		-0.5	-0.7	peptidyl-prolyl cis-trans isomerase
MMP_RS05515		-0.5	-1.5	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS07820		-0.5	-1.3	UPF0104 family protein
MMP_RS01765		-0.5	-1.1	HIT family protein
MMP_RS06400		-0.5	-0.4	4Fe-4S binding protein
MMP_RS01655		-0.5	-0.8	DsrE family protein
MMP_RS07925		-0.5	-0.7	haloacid dehalogenase
MMP_RS02890		-0.5	-1.9	TIGR00296 family protein
MMP_RS02595		-0.5	-0.4	putative zinc-binding protein
MMP_RS01865		-0.5	-0.4	GPR1/FUN34/YaaH family transporter
MMP_RS00535		-0.5	-0.9	TIGR00375 family protein
MMP_RS05535		-0.5	-1.4	hypothetical protein

Specific Phenotypes

For 3 genes in this experiment

For stress 5-fluorouracil in Methanococcus maripaludis S2

For stress 5-fluorouracil across organisms