Experiment set11S265 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Bacitracin 0.003125 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01175 -6.8 -3.8 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06400 -5.8 -1.8 4Fe-4S binding protein compare
MMP_RS04710 -5.2 -2.0 hypothetical protein compare
MMP_RS03435 -5.1 -1.8 ketol-acid reductoisomerase compare
MMP_RS03025 -4.9 -5.8 molybdenum cofactor guanylyltransferase compare
MMP_RS01755 -4.8 -1.2 DUF2097 domain-containing protein compare
MMP_RS07075 -4.8 -3.6 phosphomannomutase/phosphoglucomutase compare
MMP_RS01955 -4.6 -2.4 hypothetical protein compare
MMP_RS06730 -4.5 -2.1 phosphopantothenate/pantothenate synthetase compare
MMP_RS03315 -4.5 -1.4 ferrous iron transport protein A compare
MMP_RS02280 -4.4 -0.8 DUF211 domain-containing protein compare
MMP_RS07730 -4.3 -2.1 pyruvate synthase subunit beta compare
MMP_RS06230 -4.3 -2.7 helix-turn-helix domain-containing protein compare
MMP_RS04720 -4.2 -2.8 DedA family protein compare
MMP_RS02900 -4.1 -0.7 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00750 -4.0 -2.2 fumarate hydratase compare
MMP_RS01700 -3.9 -1.0 dihydroxy-acid dehydratase compare
MMP_RS01960 -3.7 -0.9 hypothetical protein compare
MMP_RS04780 -3.7 -2.7 ribonuclease P compare
MMP_RS00695 -3.6 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06285 -3.6 -2.0 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07635 -3.5 -6.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS01830 -3.4 -1.2 tRNA-Val compare
MMP_RS04685 -3.4 -2.3 DUF126 domain-containing protein compare
MMP_RS04890 -3.3 -0.8 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03400 -3.3 -2.1 archease compare
MMP_RS05345 -3.2 -6.6 hypothetical protein compare
MMP_RS07735 -3.0 -0.8 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06940 -3.0 -3.3 polyprenyl diphosphate synthase compare
MMP_RS08745 -3.0 -6.1 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01795 -3.0 -1.2 methanogenesis marker 6 protein compare
MMP_RS01325 -3.0 -1.5 dihydroneopterin aldolase family protein compare
MMP_RS06670 -2.9 -4.0 glucose-6-phosphate isomerase compare
MMP_RS08650 -2.8 -3.2 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07390 -2.8 -2.1 cell division protein FtsZ compare
MMP_RS01545 -2.8 -0.9 CBS domain-containing protein compare
MMP_RS02175 -2.7 -0.7 DUF1611 domain-containing protein compare
MMP_RS03110 -2.7 -5.2 glycosyltransferase family 2 protein compare
MMP_RS06315 -2.7 -0.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08440 -2.7 -2.1 cell division protein SepF compare
MMP_RS08790 -2.7 -1.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS01380 -2.7 -3.5 PHP domain-containing protein compare
MMP_RS05265 -2.6 -2.1 2-isopropylmalate synthase compare
MMP_RS07420 -2.6 -3.4 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS00515 -2.5 -0.9 DUF655 domain-containing protein compare
MMP_RS06600 -2.4 -1.1 class III signal peptide-containing protein compare
MMP_RS05905 -2.4 -5.8 undecaprenyl-diphosphate phosphatase conserved
MMP_RS08635 -2.3 -1.7 UbiA family prenyltransferase compare
MMP_RS08720 -2.3 -1.3 4Fe-4S binding protein compare
MMP_RS03600 -2.3 -1.4 triose-phosphate isomerase compare
MMP_RS00305 -2.3 -1.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS04090 -2.2 -1.7 hypothetical protein compare
MMP_RS09020 -2.2 -1.3 hypothetical protein compare
MMP_RS07845 -2.2 -2.1 LL-diaminopimelate aminotransferase compare
MMP_RS05845 -2.2 -1.3 tRNA-intron lyase compare
MMP_RS07380 -2.2 -1.6 transcription elongation factor Spt5 compare
MMP_RS05635 -2.2 -6.9 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS01270 -2.2 -11.5 prepilin peptidase compare
MMP_RS03700 -2.1 -4.5 sodium:proton antiporter compare
MMP_RS01800 -2.1 -3.1 TIGR00303 family protein compare
MMP_RS07355 -2.1 -0.8 transcription factor S compare
MMP_RS07600 -2.1 -1.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07200 -2.1 -4.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS03205 -2.1 -1.0 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS02240 -2.1 -2.1 methanogenesis marker 7 protein compare
MMP_RS08435 -2.0 -1.6 Era-like GTP-binding protein compare
MMP_RS06035 -2.0 -5.7 glycosyltransferase family 2 protein compare
MMP_RS02145 -2.0 -5.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS00685 -2.0 -1.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07385 -2.0 -1.9 protein translocase SEC61 complex subunit gamma compare
MMP_RS06120 -1.9 -1.1 UPF0147 family protein compare
MMP_RS05920 -1.9 -0.5 50S ribosomal protein L37e compare
MMP_RS03475 -1.9 -0.5 hypothetical protein compare
MMP_RS01890 -1.8 -2.6 nucleotide sugar dehydrogenase compare
MMP_RS08460 -1.8 -1.3 proteasome-activating nucleotidase compare
MMP_RS06725 -1.7 -5.0 hypothetical protein compare
MMP_RS08315 -1.7 -2.4 S-methyl-5-thioribose-1-phosphate isomerase compare
MMP_RS08855 -1.7 -5.7 hypothetical protein compare
MMP_RS09025 -1.7 -0.8 hypothetical protein compare
MMP_RS01885 -1.7 -2.7 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS05550 -1.6 -0.6 cation:proton antiporter compare
MMP_RS07710 -1.6 -3.7 cell division protein FtsZ compare
MMP_RS07330 -1.6 -8.1 membrane protein compare
MMP_RS02195 -1.6 -2.4 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03960 -1.6 -0.7 hypothetical protein compare
MMP_RS01265 -1.6 -2.2 hypothetical protein compare
MMP_RS06870 -1.6 -3.4 DedA family protein compare
MMP_RS01225 -1.5 -2.4 DUF5379 domain-containing protein compare
MMP_RS00110 -1.5 -1.2 hypothetical protein compare
MMP_RS06625 -1.5 -1.0 DNA primase compare
MMP_RS08210 -1.5 -1.2 phosphatidylglycerophosphatase A compare
MMP_RS04585 -1.5 -5.6 AIR synthase related protein compare
MMP_RS05285 -1.5 -5.7 MMPL family transporter compare
MMP_RS03350 -1.5 -2.0 winged helix-turn-helix domain-containing protein compare
MMP_RS00985 -1.4 -3.1 CDC48 family AAA ATPase compare
MMP_RS02470 -1.4 -1.0 helix-turn-helix transcriptional regulator compare
MMP_RS00040 -1.4 -2.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS00250 -1.4 -8.6 Flp pilus assembly complex ATPase component TadA compare
MMP_RS08860 -1.4 -3.6 MinD/ParA family protein compare
MMP_RS01610 -1.4 -1.5 hypothetical protein compare
MMP_RS05280 -1.4 -5.4 COG1361 S-layer family protein compare
MMP_RS03580 -1.4 -1.9 signal recognition particle-docking protein FtsY compare
MMP_RS01305 -1.4 -8.8 hypothetical protein compare
MMP_RS08155 -1.3 -4.1 hypothetical protein compare
MMP_RS01280 -1.3 -7.2 DUF515 domain-containing protein compare
MMP_RS06350 -1.3 -2.3 HesA/MoeB/ThiF family protein compare
MMP_RS05580 -1.3 -6.9 glycosyltransferase compare
MMP_RS07555 -1.3 -0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS00850 -1.3 -3.1 TIGR01177 family methyltransferase compare
MMP_RS01310 -1.3 -6.2 hypothetical protein compare
MMP_RS06290 -1.3 -2.1 DNA repair and recombination protein RadA compare
MMP_RS07605 -1.2 -1.8 diadenylate cyclase compare
MMP_RS07090 -1.2 -4.4 tRNA (adenine-N1)-methyltransferase compare
MMP_RS05430 -1.2 -2.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS08975 -1.2 -2.5 hypothetical protein compare
MMP_RS03080 -1.2 -1.5 universal stress protein compare
MMP_RS01295 -1.2 -4.5 hypothetical protein compare
MMP_RS00240 -1.2 -6.3 type II secretion system F family protein compare
MMP_RS07875 -1.2 -2.1 hypothetical protein compare
MMP_RS01905 -1.2 -3.5 glycosyltransferase compare
MMP_RS02800 -1.2 -4.0 nucleotidyltransferase domain-containing protein compare
MMP_RS02700 -1.2 -2.9 formylmethanofuran dehydrogenase subunit C compare
MMP_RS01290 -1.1 -3.9 class III signal peptide-containing protein compare
MMP_RS03140 -1.1 -3.2 hypothetical protein compare
MMP_RS07350 -1.1 -1.2 preprotein translocase subunit Sec61beta compare
MMP_RS06270 -1.1 -2.3 TIGR00300 family protein compare
MMP_RS05290 -1.1 -5.5 TetR/AcrR family transcriptional regulator compare
MMP_RS04775 -1.1 -1.5 adenosylhomocysteinase compare
MMP_RS01900 -1.1 -3.9 hypothetical protein compare
MMP_RS08280 -1.1 -1.4 proteasome assembly chaperone family protein compare
MMP_RS03015 -1.1 -4.0 GTP 3' 8-cyclase MoaA compare
MMP_RS01575 -1.1 -3.8 aldolase compare
MMP_RS03345 -1.1 -5.2 hypothetical protein compare
MMP_RS01100 -1.1 -0.8 ABC transporter ATP-binding protein compare
MMP_RS03485 -1.1 -2.5 TIGR00267 family protein compare
MMP_RS00245 -1.1 -6.8 type II secretion system F family protein compare
MMP_RS04955 -1.1 -2.6 DNA topoisomerase I compare
MMP_RS01720 -1.1 -0.8 replication factor C large subunit compare
MMP_RS08645 -1.1 -4.0 UPF0179 family protein compare
MMP_RS03305 -1.1 -2.9 winged helix-turn-helix domain-containing protein compare
MMP_RS04715 -1.0 -4.8 CBS domain-containing protein compare
MMP_RS00300 -1.0 -0.4 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS08195 -1.0 -3.5 hypothetical protein compare
MMP_RS00830 -1.0 -1.4 purine phosphoribosyltransferase family protein compare
MMP_RS04520 -1.0 -2.0 nucleoside deaminase compare
MMP_RS03395 -1.0 -2.1 hypothetical protein compare
MMP_RS09045 -1.0 -5.7 class III signal peptide-containing protein compare
MMP_RS01275 -1.0 -3.8 class III signal peptide-containing protein compare
MMP_RS08715 -1.0 -0.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06295 -1.0 -2.5 methanogenesis marker 14 protein compare
MMP_RS06365 -1.0 -1.1 hypothetical protein compare
MMP_RS02345 -1.0 -1.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01315 -1.0 -7.6 DUF2341 domain-containing protein compare
MMP_RS00140 -1.0 -3.6 DUF192 domain-containing protein compare
MMP_RS07820 -1.0 -1.4 UPF0104 family protein compare
MMP_RS05640 -1.0 -2.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS01285 -1.0 -3.6 hypothetical protein compare
MMP_RS02290 -1.0 -2.6 MBL fold metallo-hydrolase compare
MMP_RS02135 -1.0 -1.8 DUF5612 domain-containing protein compare
MMP_RS04310 -1.0 -1.6 hypothetical protein compare
MMP_RS06855 -1.0 -2.8 hypothetical protein compare
MMP_RS07815 -0.9 -0.6 DUF2120 domain-containing protein compare
MMP_RS01865 -0.9 -0.7 GPR1/FUN34/YaaH family transporter compare
MMP_RS01500 -0.9 -0.7 CBS domain-containing protein compare
MMP_RS01470 -0.9 -1.3 ATP-binding cassette domain-containing protein compare
MMP_RS06585 -0.9 -0.8 DMT family protein compare
MMP_RS07955 -0.9 -1.6 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS02805 -0.9 -0.6 HEPN domain-containing protein compare
MMP_RS05295 -0.9 -2.9 minichromosome maintenance protein MCM compare
MMP_RS02130 -0.9 -2.9 zinc metalloprotease HtpX compare
MMP_RS08785 -0.9 -0.4 RNA-protein complex protein Nop10 compare
MMP_RS07755 -0.9 -0.6 DUF555 domain-containing protein compare
MMP_RS04695 -0.9 -2.6 selenide water dikinase SelD compare
MMP_RS07685 -0.9 -2.8 TIGR01212 family radical SAM protein compare
MMP_RS08675 -0.9 -0.8 class III signal peptide-containing protein compare
MMP_RS06355 -0.9 -1.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS02705 -0.9 -2.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS05930 -0.8 -0.7 3-isopropylmalate dehydratase large subunit compare
MMP_RS03775 -0.8 -1.8 4Fe-4S dicluster domain-containing protein compare
MMP_RS01460 -0.8 -1.3 hypothetical protein compare
MMP_RS00915 -0.8 -2.7 DUF116 domain-containing protein compare
MMP_RS00655 -0.8 -1.2 hypothetical protein compare
MMP_RS07885 -0.8 -1.2 tripartite tricarboxylate transporter permease compare
MMP_RS04485 -0.8 -3.4 putative beta-lysine N-acetyltransferase compare
MMP_RS01745 -0.8 -2.4 AMP phosphorylase compare
MMP_RS04265 -0.8 -1.1 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS03320 -0.8 -1.4 metal-dependent transcriptional regulator compare
MMP_RS08660 -0.8 -2.6 DHH family phosphoesterase compare
MMP_RS05555 -0.8 -0.6 DUF4040 domain-containing protein compare
MMP_RS08995 -0.8 -0.6 hypothetical protein compare
MMP_RS09035 -0.8 -1.1 hypothetical protein compare
MMP_RS05250 -0.8 -1.6 NFYB/HAP3 family transcription factor subunit compare
MMP_RS07445 -0.8 -2.6 helix-turn-helix domain-containing protein compare
MMP_RS06885 -0.8 -1.2 50S ribosome-binding GTPase compare
MMP_RS00810 -0.8 -1.7 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS04360 -0.7 -1.6 hypothetical protein compare
MMP_RS05540 -0.7 -1.8 hypothetical protein compare
MMP_RS06555 -0.7 -1.2 cupin domain-containing protein compare
MMP_RS07005 -0.7 -0.3 4Fe-4S binding protein compare
MMP_RS04740 -0.7 -1.8 DUF473 domain-containing protein compare


Specific Phenotypes

For 2 genes in this experiment

For stress Bacitracin in Methanococcus maripaludis S2

For stress Bacitracin across organisms