Experiment set11S255 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Zinc Pyrithione 0.0142857142857143 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS03600 -7.5 -1.8 triose-phosphate isomerase compare
MMP_RS08715 -6.9 -1.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00300 -5.6 -0.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03435 -5.3 -1.5 ketol-acid reductoisomerase compare
MMP_RS07005 -5.3 -0.6 4Fe-4S binding protein compare
MMP_RS00695 -4.5 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06400 -4.1 -1.3 4Fe-4S binding protein compare
MMP_RS00985 -3.7 -4.8 CDC48 family AAA ATPase compare
MMP_RS03640 -3.6 -3.2 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01265 -3.4 -2.4 hypothetical protein compare
MMP_RS07755 -3.2 -1.0 DUF555 domain-containing protein compare
MMP_RS08940 -3.0 -1.3 MetS family NSS transporter small subunit compare
MMP_RS03475 -3.0 -0.5 hypothetical protein compare
MMP_RS06840 -3.0 -0.8 DNA-directed RNA polymerase subunit N compare
MMP_RS02340 -2.9 -1.6 DNA-directed RNA polymerase subunit E'' compare
MMP_RS01195 -2.8 -1.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01225 -2.8 -5.1 DUF5379 domain-containing protein compare
MMP_RS00515 -2.8 -0.8 DUF655 domain-containing protein compare
MMP_RS07540 -2.8 -3.0 CBS domain-containing protein compare
MMP_RS01610 -2.8 -1.9 hypothetical protein compare
MMP_RS03315 -2.7 -1.2 ferrous iron transport protein A compare
MMP_RS01175 -2.6 -2.8 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS09055 -2.6 -1.0 CAP domain-containing protein compare
MMP_RS02800 -2.6 -6.1 nucleotidyltransferase domain-containing protein compare
MMP_RS06355 -2.6 -2.0 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01075 -2.6 -1.3 hypothetical protein compare
MMP_RS06350 -2.5 -5.3 HesA/MoeB/ThiF family protein compare
MMP_RS05515 -2.5 -5.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS04775 -2.5 -3.5 adenosylhomocysteinase compare
MMP_RS03015 -2.5 -8.0 GTP 3' 8-cyclase MoaA compare
MMP_RS07845 -2.5 -2.7 LL-diaminopimelate aminotransferase compare
MMP_RS02355 -2.4 -2.1 30S ribosomal protein S27ae compare
MMP_RS07350 -2.4 -1.9 preprotein translocase subunit Sec61beta compare
MMP_RS02240 -2.3 -2.4 methanogenesis marker 7 protein compare
MMP_RS07635 -2.3 -6.7 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS01500 -2.3 -1.2 CBS domain-containing protein compare
MMP_RS08210 -2.3 -1.5 phosphatidylglycerophosphatase A compare
MMP_RS03110 -2.2 -4.3 glycosyltransferase family 2 protein compare
MMP_RS04710 -2.2 -1.8 hypothetical protein compare
MMP_RS01960 -2.1 -0.7 hypothetical protein compare
MMP_RS07420 -2.1 -4.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08675 -2.1 -3.0 class III signal peptide-containing protein compare
MMP_RS02875 -2.1 -5.6 chorismate pyruvate-lyase family protein compare
MMP_RS07600 -2.0 -1.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02230 -2.0 -8.4 sodium-dependent transporter compare
MMP_RS06295 -2.0 -5.1 methanogenesis marker 14 protein compare
MMP_RS01310 -2.0 -11.3 hypothetical protein compare
MMP_RS06285 -2.0 -1.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01280 -2.0 -9.7 DUF515 domain-containing protein compare
MMP_RS08720 -2.0 -1.0 4Fe-4S binding protein compare
MMP_RS08790 -2.0 -1.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS00250 -2.0 -11.0 Flp pilus assembly complex ATPase component TadA compare
MMP_RS07730 -2.0 -1.6 pyruvate synthase subunit beta compare
MMP_RS01190 -2.0 -6.1 cadmium-translocating P-type ATPase conserved
MMP_RS09020 -2.0 -1.1 hypothetical protein compare
MMP_RS01795 -1.9 -0.9 methanogenesis marker 6 protein compare
MMP_RS00245 -1.9 -12.8 type II secretion system F family protein compare
MMP_RS07355 -1.9 -0.7 transcription factor S compare
MMP_RS04890 -1.9 -0.5 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS01755 -1.9 -1.0 DUF2097 domain-containing protein compare
MMP_RS02235 -1.9 -6.4 CBS domain-containing protein compare
MMP_RS01270 -1.9 -8.6 prepilin peptidase compare
MMP_RS03700 -1.9 -5.1 sodium:proton antiporter compare
MMP_RS00735 -1.9 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS08435 -1.9 -1.9 Era-like GTP-binding protein compare
MMP_RS00810 -1.9 -5.7 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08855 -1.8 -7.2 hypothetical protein compare
MMP_RS03095 -1.8 -4.6 diphthine synthase compare
MMP_RS07735 -1.8 -0.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS04875 -1.8 -2.8 energy-converting hydrogenase B subunit P compare
MMP_RS00040 -1.8 -3.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS08820 -1.8 -3.9 hypothetical protein compare
MMP_RS01305 -1.8 -12.1 hypothetical protein compare
MMP_RS05540 -1.8 -3.2 hypothetical protein compare
MMP_RS06120 -1.8 -1.3 UPF0147 family protein compare
MMP_RS01275 -1.8 -5.0 class III signal peptide-containing protein compare
MMP_RS07545 -1.7 -0.7 HTH domain-containing protein compare
MMP_RS05845 -1.7 -1.2 tRNA-intron lyase compare
MMP_RS01545 -1.7 -0.7 CBS domain-containing protein compare
MMP_RS05430 -1.7 -4.0 TIGR00288 family NYN domain-containing protein compare
MMP_RS01285 -1.7 -6.5 hypothetical protein compare
MMP_RS00240 -1.7 -9.7 type II secretion system F family protein compare
MMP_RS04605 -1.7 -2.1 cobalt ECF transporter T component CbiQ compare
MMP_RS06105 -1.6 -5.5 hydrogenase maturation peptidase HycI compare
MMP_RS06865 -1.6 -1.6 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06340 -1.6 -4.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS01295 -1.6 -8.0 hypothetical protein compare
MMP_RS08195 -1.6 -4.9 hypothetical protein compare
MMP_RS01085 -1.6 -1.4 hypothetical protein compare
MMP_RS07820 -1.6 -2.7 UPF0104 family protein compare
MMP_RS01315 -1.6 -11.5 DUF2341 domain-containing protein compare
MMP_RS01290 -1.6 -7.3 class III signal peptide-containing protein compare
MMP_RS08860 -1.6 -4.3 MinD/ParA family protein compare
MMP_RS02195 -1.5 -1.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS01325 -1.5 -1.1 dihydroneopterin aldolase family protein compare
MMP_RS06895 -1.5 -0.9 selenocysteine-specific translation elongation factor compare
MMP_RS04615 -1.5 -1.9 PDGLE domain-containing protein compare
MMP_RS06725 -1.5 -6.2 hypothetical protein compare
MMP_RS06900 -1.5 -2.0 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS04900 -1.5 -10.5 hypothetical protein compare
MMP_RS01725 -1.5 -2.5 class I SAM-dependent methyltransferase family protein compare
MMP_RS03080 -1.5 -2.0 universal stress protein compare
MMP_RS07710 -1.5 -4.1 cell division protein FtsZ compare
MMP_RS01365 -1.5 -2.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS05920 -1.4 -0.4 50S ribosomal protein L37e compare
MMP_RS06885 -1.4 -1.6 50S ribosome-binding GTPase compare
MMP_RS07330 -1.4 -9.1 membrane protein compare
MMP_RS03485 -1.4 -3.1 TIGR00267 family protein compare
MMP_RS02245 -1.4 -2.0 hypothetical protein compare
MMP_RS00320 -1.4 -1.2 class I SAM-dependent methyltransferase compare
MMP_RS03140 -1.4 -7.2 hypothetical protein compare
MMP_RS05815 -1.4 -1.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS08360 -1.4 -1.8 hypothetical protein compare
MMP_RS05550 -1.4 -0.5 cation:proton antiporter compare
MMP_RS03145 -1.4 -4.7 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS00140 -1.4 -3.3 DUF192 domain-containing protein compare
MMP_RS05635 -1.3 -5.0 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06730 -1.3 -1.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS08645 -1.3 -5.1 UPF0179 family protein compare
MMP_RS05425 -1.3 -2.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06315 -1.3 -0.7 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS04585 -1.3 -5.2 AIR synthase related protein compare
MMP_RS00965 -1.3 -2.2 hypothetical protein compare
MMP_RS07525 -1.3 -3.5 4Fe-4S binding protein compare
MMP_RS06035 -1.3 -5.8 glycosyltransferase family 2 protein compare
MMP_RS03580 -1.3 -1.8 signal recognition particle-docking protein FtsY compare
MMP_RS00725 -1.3 -3.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06525 -1.3 -0.8 YciI family protein compare
MMP_RS03025 -1.3 -3.3 molybdenum cofactor guanylyltransferase compare
MMP_RS08690 -1.3 -3.5 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS07605 -1.3 -1.7 diadenylate cyclase compare
MMP_RS03250 -1.2 -2.6 MJ1244 family protein compare
MMP_RS00115 -1.2 -5.4 radical SAM protein compare
MMP_RS01220 -1.2 -3.6 hypothetical protein compare
MMP_RS05580 -1.2 -7.9 glycosyltransferase compare
MMP_RS05445 -1.2 -3.6 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS03420 -1.2 -2.3 acetolactate synthase small subunit compare
MMP_RS00555 -1.2 -3.7 MFS transporter compare
MMP_RS02900 -1.2 -0.4 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01890 -1.2 -1.9 nucleotide sugar dehydrogenase compare
MMP_RS00120 -1.2 -2.4 LysR family transcriptional regulator compare
MMP_RS03445 -1.2 -0.6 methanogenesis marker 17 protein compare
MMP_RS00060 -1.2 -1.1 3-dehydroquinate synthase II compare
MMP_RS08165 -1.2 -1.1 phosphoglycerate dehydrogenase compare
MMP_RS08365 -1.2 -2.6 energy conserving hydrogenase EhbF compare
MMP_RS06855 -1.2 -4.6 hypothetical protein compare
MMP_RS08745 -1.2 -3.1 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS05555 -1.2 -1.0 DUF4040 domain-containing protein compare
MMP_RS01380 -1.2 -1.6 PHP domain-containing protein compare
MMP_RS02940 -1.1 -4.0 TatD family hydrolase compare
MMP_RS01800 -1.1 -1.7 TIGR00303 family protein compare
MMP_RS01045 -1.1 -2.9 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS03125 -1.1 -2.9 cell division ATPase MinD compare
MMP_RS00730 -1.1 -1.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS01925 -1.1 -3.8 DUF1616 domain-containing protein compare
MMP_RS03550 -1.1 -1.0 DUF2124 domain-containing protein compare
MMP_RS05965 -1.1 -0.8 carboxymuconolactone decarboxylase family protein compare
MMP_RS05950 -1.1 -3.7 nickel-dependent hydrogenase large subunit compare
MMP_RS05955 -1.1 -0.9 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS08330 -1.1 -2.9 NADH-quinone oxidoreductase subunit H compare
MMP_RS00235 -1.1 -4.8 HDIG domain-containing protein compare
MMP_RS03590 -1.1 -2.0 METTL5 family protein compare
MMP_RS07700 -1.1 -4.9 DUF1188 domain-containing protein compare
MMP_RS08400 -1.1 -0.9 MJ0307 family thioredoxin compare
MMP_RS05765 -1.1 -2.5 M42 family metallopeptidase compare
MMP_RS02145 -1.1 -2.8 winged helix-turn-helix transcriptional regulator compare
MMP_RS00750 -1.0 -1.2 fumarate hydratase compare
MMP_RS07575 -1.0 -1.5 RNA ligase partner protein compare
MMP_RS07750 -1.0 -2.2 DUF357 domain-containing protein compare
MMP_RS01180 -1.0 -1.0 XTP/dITP diphosphatase compare
MMP_RS07695 -1.0 -2.5 DUF3236 domain-containing protein compare
MMP_RS08300 -1.0 -0.6 metal-sulfur cluster assembly factor compare
MMP_RS04090 -1.0 -1.5 hypothetical protein compare
MMP_RS04790 -1.0 -4.0 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS00570 -1.0 -1.1 protein-L-isoaspartate O-methyltransferase compare
MMP_RS01335 -1.0 -1.0 prefoldin subunit beta compare
MMP_RS05925 -1.0 -1.2 small nuclear ribonucleoprotein compare
MMP_RS04695 -1.0 -2.4 selenide water dikinase SelD compare
MMP_RS06020 -1.0 -1.5 archaeoflavoprotein AfpA compare
MMP_RS06940 -1.0 -1.4 polyprenyl diphosphate synthase compare
MMP_RS03090 -1.0 -3.1 cation:proton antiporter compare
MMP_RS04685 -1.0 -0.9 DUF126 domain-containing protein compare
MMP_RS03205 -1.0 -0.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS01900 -1.0 -5.0 hypothetical protein compare
MMP_RS07875 -1.0 -2.5 hypothetical protein compare
MMP_RS06625 -0.9 -0.8 DNA primase compare
MMP_RS03035 -0.9 -1.3 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02780 -0.9 -4.2 hypothetical protein compare
MMP_RS00520 -0.9 -0.8 RNA polymerase Rpb4 family protein compare
MMP_RS08750 -0.9 -0.9 hypothetical protein compare
MMP_RS01840 -0.9 -2.5 TIGR00289 family protein compare
MMP_RS07955 -0.9 -2.1 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06925 -0.9 -1.2 ribonuclease VapC4 compare
MMP_RS07200 -0.9 -2.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS02805 -0.9 -0.6 HEPN domain-containing protein compare
MMP_RS08830 -0.9 -1.7 GTP-binding protein compare
MMP_RS01905 -0.9 -4.9 glycosyltransferase compare
MMP_RS08660 -0.9 -3.0 DHH family phosphoesterase compare
MMP_RS08355 -0.9 -1.6 Na(+)/H(+) antiporter subunit B compare
MMP_RS01655 -0.8 -1.2 DsrE family protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Zinc Pyrithione in Methanococcus maripaludis S2

For stress Zinc Pyrithione across organisms