Experiment set11S254 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Nitrofurantoin 0.1 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS01545 -7.0 -0.7 CBS domain-containing protein compare
MMP_RS05550 -6.2 -0.7 cation:proton antiporter compare
MMP_RS02175 -6.2 -0.7 DUF1611 domain-containing protein compare
MMP_RS07555 -5.9 -0.6 monovalent cation/H+ antiporter subunit E compare
MMP_RS03080 -5.3 -2.7 universal stress protein compare
MMP_RS08300 -4.6 -1.2 metal-sulfur cluster assembly factor compare
MMP_RS06625 -4.4 -1.8 DNA primase compare
MMP_RS07860 -4.1 -0.6 hypothetical protein compare
MMP_RS07355 -4.0 -0.8 transcription factor S compare
MMP_RS07735 -3.9 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS03250 -3.9 -3.8 MJ1244 family protein compare
MMP_RS01665 -3.7 -4.2 DUF2111 domain-containing protein compare
MMP_RS02235 -3.7 -11.1 CBS domain-containing protein compare
MMP_RS07630 -3.5 -1.2 ATP-binding cassette domain-containing protein compare
MMP_RS04900 -3.4 -17.6 hypothetical protein compare
MMP_RS02240 -3.4 -2.9 methanogenesis marker 7 protein compare
MMP_RS05425 -3.4 -3.9 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06230 -3.4 -2.7 helix-turn-helix domain-containing protein compare
MMP_RS03445 -3.3 -0.9 methanogenesis marker 17 protein compare
MMP_RS01265 -3.2 -2.6 hypothetical protein compare
MMP_RS01575 -3.1 -4.4 aldolase compare
MMP_RS01225 -3.1 -4.1 DUF5379 domain-containing protein compare
MMP_RS09020 -3.1 -1.4 hypothetical protein compare
MMP_RS07005 -3.0 -0.6 4Fe-4S binding protein compare
MMP_RS03435 -3.0 -1.6 ketol-acid reductoisomerase compare
MMP_RS05865 -2.9 -3.1 hypothetical protein compare
MMP_RS03640 -2.9 -2.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS03580 -2.9 -2.5 signal recognition particle-docking protein FtsY compare
MMP_RS06675 -2.9 -8.8 ADP-specific phosphofructokinase compare
MMP_RS01195 -2.8 -1.3 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01175 -2.8 -2.7 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08000 -2.7 -10.4 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS06350 -2.7 -5.2 HesA/MoeB/ThiF family protein compare
MMP_RS06725 -2.7 -6.8 hypothetical protein compare
MMP_RS05815 -2.7 -1.8 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS02875 -2.7 -6.6 chorismate pyruvate-lyase family protein compare
MMP_RS05925 -2.6 -2.7 small nuclear ribonucleoprotein compare
MMP_RS01270 -2.6 -13.8 prepilin peptidase compare
MMP_RS07845 -2.5 -2.9 LL-diaminopimelate aminotransferase compare
MMP_RS07380 -2.5 -1.6 transcription elongation factor Spt5 compare
MMP_RS07635 -2.5 -5.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08720 -2.5 -1.3 4Fe-4S binding protein compare
MMP_RS02290 -2.5 -5.4 MBL fold metallo-hydrolase compare
MMP_RS08790 -2.4 -1.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS03315 -2.4 -1.1 ferrous iron transport protein A compare
MMP_RS07600 -2.4 -2.1 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06295 -2.4 -5.4 methanogenesis marker 14 protein compare
MMP_RS04710 -2.4 -1.8 hypothetical protein compare
MMP_RS03025 -2.4 -4.1 molybdenum cofactor guanylyltransferase compare
MMP_RS03015 -2.4 -6.5 GTP 3' 8-cyclase MoaA compare
MMP_RS08210 -2.4 -1.7 phosphatidylglycerophosphatase A compare
MMP_RS00735 -2.4 -3.0 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06035 -2.3 -7.6 glycosyltransferase family 2 protein compare
MMP_RS01085 -2.3 -1.8 hypothetical protein compare
MMP_RS02145 -2.3 -6.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS07545 -2.3 -0.9 HTH domain-containing protein compare
MMP_RS00315 -2.3 -4.4 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS04605 -2.2 -3.0 cobalt ECF transporter T component CbiQ compare
MMP_RS06315 -2.2 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08635 -2.2 -1.4 UbiA family prenyltransferase compare
MMP_RS08675 -2.2 -3.1 class III signal peptide-containing protein compare
MMP_RS05515 -2.2 -5.9 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS05580 -2.2 -11.4 glycosyltransferase compare
MMP_RS02195 -2.1 -2.9 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS00810 -2.1 -6.2 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS00250 -2.1 -11.9 Flp pilus assembly complex ATPase component TadA compare
MMP_RS04780 -2.1 -2.5 ribonuclease P compare
MMP_RS06840 -2.1 -0.7 DNA-directed RNA polymerase subunit N compare
MMP_RS01755 -2.1 -1.0 DUF2097 domain-containing protein compare
MMP_RS01880 -2.1 -4.6 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06730 -2.1 -1.4 phosphopantothenate/pantothenate synthetase compare
MMP_RS01885 -2.1 -5.2 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS05635 -2.0 -5.9 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06340 -2.0 -5.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07075 -2.0 -2.4 phosphomannomutase/phosphoglucomutase compare
MMP_RS01745 -2.0 -4.4 AMP phosphorylase compare
MMP_RS07330 -2.0 -11.0 membrane protein compare
MMP_RS08745 -2.0 -4.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS04615 -2.0 -2.6 PDGLE domain-containing protein compare
MMP_RS01795 -2.0 -1.0 methanogenesis marker 6 protein compare
MMP_RS01960 -2.0 -0.7 hypothetical protein compare
MMP_RS01280 -2.0 -12.1 DUF515 domain-containing protein compare
MMP_RS08855 -1.9 -9.0 hypothetical protein compare
MMP_RS05555 -1.9 -1.3 DUF4040 domain-containing protein compare
MMP_RS08195 -1.9 -6.6 hypothetical protein compare
MMP_RS00185 -1.9 -10.1 potassium channel protein compare
MMP_RS01725 -1.9 -3.1 class I SAM-dependent methyltransferase family protein compare
MMP_RS01610 -1.9 -2.5 hypothetical protein compare
MMP_RS00915 -1.9 -4.0 DUF116 domain-containing protein compare
MMP_RS01310 -1.9 -9.1 hypothetical protein compare
MMP_RS06020 -1.9 -2.7 archaeoflavoprotein AfpA compare
MMP_RS00040 -1.9 -3.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01285 -1.9 -7.3 hypothetical protein compare
MMP_RS00725 -1.9 -4.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04890 -1.9 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00300 -1.9 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS04850 -1.9 -9.9 UPF0254 family protein compare
MMP_RS02800 -1.9 -3.0 nucleotidyltransferase domain-containing protein compare
MMP_RS05430 -1.9 -3.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS06285 -1.8 -1.7 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00730 -1.8 -4.0 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS07695 -1.8 -4.0 DUF3236 domain-containing protein compare
MMP_RS01295 -1.8 -10.0 hypothetical protein compare
MMP_RS01500 -1.8 -1.5 CBS domain-containing protein compare
MMP_RS00695 -1.8 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00985 -1.8 -3.1 CDC48 family AAA ATPase compare
MMP_RS08165 -1.8 -1.6 phosphoglycerate dehydrogenase compare
MMP_RS08330 -1.8 -3.8 NADH-quinone oxidoreductase subunit H compare
MMP_RS09055 -1.8 -0.9 CAP domain-containing protein compare
MMP_RS01380 -1.8 -3.7 PHP domain-containing protein compare
MMP_RS01290 -1.8 -6.2 class III signal peptide-containing protein compare
MMP_RS00240 -1.7 -9.7 type II secretion system F family protein compare
MMP_RS06105 -1.7 -5.3 hydrogenase maturation peptidase HycI compare
MMP_RS06925 -1.7 -1.8 ribonuclease VapC4 compare
MMP_RS08435 -1.7 -1.7 Era-like GTP-binding protein compare
MMP_RS01385 -1.7 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01275 -1.7 -5.6 class III signal peptide-containing protein compare
MMP_RS01305 -1.7 -10.9 hypothetical protein compare
MMP_RS01800 -1.7 -2.9 TIGR00303 family protein compare
MMP_RS00245 -1.7 -12.2 type II secretion system F family protein compare
MMP_RS06400 -1.7 -0.9 4Fe-4S binding protein compare
MMP_RS07755 -1.7 -1.0 DUF555 domain-containing protein compare
MMP_RS01875 -1.7 -5.1 N-acetyltransferase compare
MMP_RS07605 -1.6 -2.0 diadenylate cyclase compare
MMP_RS07700 -1.6 -6.7 DUF1188 domain-containing protein compare
MMP_RS05540 -1.6 -1.7 hypothetical protein compare
MMP_RS06885 -1.6 -1.7 50S ribosome-binding GTPase compare
MMP_RS06630 -1.6 -0.7 UPF0058 family protein compare
MMP_RS03125 -1.6 -3.8 cell division ATPase MinD compare
MMP_RS08370 -1.6 -0.5 cation:proton antiporter subunit C compare
MMP_RS01315 -1.6 -11.6 DUF2341 domain-containing protein compare
MMP_RS01890 -1.6 -2.6 nucleotide sugar dehydrogenase compare
MMP_RS04585 -1.6 -5.9 AIR synthase related protein compare
MMP_RS01370 -1.6 -5.8 acetate--CoA ligase family protein compare
MMP_RS05640 -1.6 -3.6 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS08940 -1.5 -1.2 MetS family NSS transporter small subunit compare
MMP_RS03550 -1.5 -1.0 DUF2124 domain-containing protein compare
MMP_RS07200 -1.5 -3.9 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06175 -1.5 -3.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS00535 -1.5 -0.9 TIGR00375 family protein compare
MMP_RS07420 -1.5 -3.2 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS00750 -1.5 -1.4 fumarate hydratase compare
MMP_RS06355 -1.5 -1.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS04685 -1.5 -2.0 DUF126 domain-containing protein compare
MMP_RS06670 -1.5 -3.4 glucose-6-phosphate isomerase compare
MMP_RS00140 -1.5 -3.9 DUF192 domain-containing protein compare
MMP_RS08860 -1.5 -5.0 MinD/ParA family protein compare
MMP_RS03600 -1.4 -1.0 triose-phosphate isomerase compare
MMP_RS01830 -1.4 -1.0 tRNA-Val compare
MMP_RS02780 -1.4 -5.3 hypothetical protein compare
MMP_RS06280 -1.4 -4.1 alpha-glucan family phosphorylase compare
MMP_RS05695 -1.3 -4.4 phospholipase D-like domain-containing protein compare
MMP_RS08645 -1.3 -4.6 UPF0179 family protein compare
MMP_RS05345 -1.3 -3.3 hypothetical protein compare
MMP_RS08715 -1.3 -0.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS03205 -1.3 -0.9 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS04125 -1.3 -1.8 TetR/AcrR family transcriptional regulator compare
MMP_RS06120 -1.3 -1.3 UPF0147 family protein compare
MMP_RS06895 -1.3 -0.9 selenocysteine-specific translation elongation factor compare
MMP_RS05850 -1.2 -2.5 Ldh family oxidoreductase compare
MMP_RS07750 -1.2 -2.6 DUF357 domain-containing protein compare
MMP_RS07730 -1.2 -1.1 pyruvate synthase subunit beta compare
MMP_RS05420 -1.2 -1.8 DUF61 family protein compare
MMP_RS07875 -1.2 -3.8 hypothetical protein compare
MMP_RS05535 -1.2 -3.2 hypothetical protein compare
MMP_RS08820 -1.2 -3.4 hypothetical protein compare
MMP_RS05415 -1.2 -2.3 DUF22 domain-containing protein compare
MMP_RS05295 -1.2 -5.6 minichromosome maintenance protein MCM compare
MMP_RS08155 -1.2 -3.6 hypothetical protein compare
MMP_RS01900 -1.2 -6.1 hypothetical protein compare
MMP_RS01325 -1.2 -1.0 dihydroneopterin aldolase family protein compare
MMP_RS03700 -1.2 -3.7 sodium:proton antiporter compare
MMP_RS01975 -1.2 -6.2 hypothetical protein compare
MMP_RS02345 -1.2 -1.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS09045 -1.2 -7.5 class III signal peptide-containing protein compare
MMP_RS03485 -1.1 -2.9 TIGR00267 family protein compare
MMP_RS07955 -1.1 -2.8 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS00520 -1.1 -1.1 RNA polymerase Rpb4 family protein compare
MMP_RS03120 -1.1 -1.7 hypothetical protein compare
MMP_RS08830 -1.1 -4.6 GTP-binding protein compare
MMP_RS06485 -1.1 -0.5 zinc ribbon domain-containing protein compare
MMP_RS01075 -1.1 -0.8 hypothetical protein compare
MMP_RS04720 -1.1 -1.3 DedA family protein compare
MMP_RS05920 -1.1 -0.3 50S ribosomal protein L37e compare
MMP_RS04620 -1.1 -3.8 cobalt transporter CbiM compare
MMP_RS06170 -1.1 -2.8 ABC transporter ATP-binding protein compare
MMP_RS07615 -1.1 -3.0 energy-coupling factor ABC transporter permease compare
MMP_RS07820 -1.1 -2.3 UPF0104 family protein compare
MMP_RS08360 -1.1 -2.0 hypothetical protein compare
MMP_RS07525 -1.1 -2.8 4Fe-4S binding protein compare
MMP_RS08995 -1.1 -0.8 hypothetical protein compare
MMP_RS08225 -1.1 -3.9 RimK family alpha-L-glutamate ligase compare
MMP_RS04955 -1.1 -3.0 DNA topoisomerase I compare
MMP_RS01655 -1.1 -1.2 DsrE family protein compare
MMP_RS04480 -1.0 -5.8 lysine 2 3-aminomutase compare
MMP_RS01140 -1.0 -1.5 molybdate ABC transporter permease subunit compare
MMP_RS03440 -1.0 -0.7 MoaD/ThiS family protein compare
MMP_RS06980 -1.0 -3.1 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS08440 -1.0 -1.3 cell division protein SepF compare
MMP_RS01790 -1.0 -2.5 restriction endonuclease compare


Specific Phenotypes

For 1 genes in this experiment

For stress Nitrofurantoin in Methanococcus maripaludis S2

For stress Nitrofurantoin across organisms