Experiment set11S241 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Anhydrotetracycline hydrochloride 0.05 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS05550 -6.3 -0.7 cation:proton antiporter compare
MMP_RS08300 -5.7 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS07005 -5.3 -0.6 4Fe-4S binding protein compare
MMP_RS08720 -5.0 -1.6 4Fe-4S binding protein compare
MMP_RS03315 -4.1 -1.4 ferrous iron transport protein A compare
MMP_RS04710 -3.6 -2.0 hypothetical protein compare
MMP_RS07755 -3.2 -1.1 DUF555 domain-containing protein compare
MMP_RS01800 -3.0 -4.3 TIGR00303 family protein compare
MMP_RS01005 -3.0 -1.4 riboflavin synthase compare
MMP_RS00520 -2.8 -1.6 RNA polymerase Rpb4 family protein compare
MMP_RS01175 -2.7 -4.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06295 -2.7 -6.8 methanogenesis marker 14 protein compare
MMP_RS03385 -2.5 -1.0 cation diffusion facilitator family transporter compare
MMP_RS06285 -2.5 -2.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07845 -2.5 -3.3 LL-diaminopimelate aminotransferase compare
MMP_RS01265 -2.4 -3.6 hypothetical protein compare
MMP_RS01545 -2.4 -1.0 CBS domain-containing protein compare
MMP_RS00300 -2.4 -0.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS04780 -2.3 -2.6 ribonuclease P compare
MMP_RS06900 -2.3 -2.6 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS04890 -2.3 -0.7 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS08210 -2.3 -1.9 phosphatidylglycerophosphatase A compare
MMP_RS00110 -2.2 -2.4 hypothetical protein compare
MMP_RS00985 -2.2 -4.8 CDC48 family AAA ATPase compare
MMP_RS02195 -2.2 -3.5 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS02240 -2.2 -3.0 methanogenesis marker 7 protein compare
MMP_RS03445 -2.2 -0.9 methanogenesis marker 17 protein compare
MMP_RS03025 -2.2 -6.1 molybdenum cofactor guanylyltransferase compare
MMP_RS06350 -2.2 -7.7 HesA/MoeB/ThiF family protein compare
MMP_RS01610 -2.2 -2.9 hypothetical protein compare
MMP_RS00810 -2.2 -8.6 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS05845 -2.2 -1.7 tRNA-intron lyase compare
MMP_RS08820 -2.1 -5.6 hypothetical protein compare
MMP_RS04685 -2.1 -2.8 DUF126 domain-containing protein compare
MMP_RS07635 -2.1 -6.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04720 -2.1 -2.6 DedA family protein compare
MMP_RS03640 -2.1 -3.1 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07605 -2.1 -2.9 diadenylate cyclase compare
MMP_RS01755 -2.1 -1.3 DUF2097 domain-containing protein compare
MMP_RS06120 -2.0 -1.4 UPF0147 family protein compare
MMP_RS00695 -2.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS03035 -2.0 -3.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS08440 -2.0 -2.1 cell division protein SepF compare
MMP_RS02800 -2.0 -7.5 nucleotidyltransferase domain-containing protein compare
MMP_RS06315 -2.0 -1.0 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS07390 -2.0 -1.6 cell division protein FtsZ compare
MMP_RS06885 -2.0 -2.3 50S ribosome-binding GTPase compare
MMP_RS01955 -2.0 -2.2 hypothetical protein compare
MMP_RS06340 -2.0 -7.0 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS02145 -1.9 -6.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS02900 -1.9 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS03580 -1.9 -2.8 signal recognition particle-docking protein FtsY compare
MMP_RS01895 -1.9 -9.1 flippase compare
MMP_RS06625 -1.9 -1.7 DNA primase compare
MMP_RS00895 -1.9 -3.5 hypothetical protein compare
MMP_RS08650 -1.9 -2.4 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07750 -1.9 -4.8 DUF357 domain-containing protein compare
MMP_RS04900 -1.9 -14.8 hypothetical protein compare
MMP_RS05540 -1.9 -3.0 hypothetical protein compare
MMP_RS01225 -1.8 -4.6 DUF5379 domain-containing protein compare
MMP_RS06925 -1.8 -2.5 ribonuclease VapC4 compare
MMP_RS07075 -1.8 -3.2 phosphomannomutase/phosphoglucomutase compare
MMP_RS00115 -1.8 -9.9 radical SAM protein compare
MMP_RS08675 -1.8 -2.8 class III signal peptide-containing protein compare
MMP_RS07420 -1.8 -3.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03700 -1.8 -5.8 sodium:proton antiporter compare
MMP_RS05245 -1.8 -8.2 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06355 -1.8 -2.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01720 -1.7 -1.6 replication factor C large subunit compare
MMP_RS08370 -1.7 -0.5 cation:proton antiporter subunit C compare
MMP_RS00915 -1.7 -6.0 DUF116 domain-containing protein compare
MMP_RS03110 -1.7 -4.9 glycosyltransferase family 2 protein compare
MMP_RS05815 -1.7 -1.9 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS04585 -1.7 -8.4 AIR synthase related protein compare
MMP_RS01365 -1.7 -2.7 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07200 -1.7 -5.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS03600 -1.7 -1.7 triose-phosphate isomerase compare
MMP_RS08745 -1.7 -4.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00060 -1.7 -1.5 3-dehydroquinate synthase II compare
MMP_RS06730 -1.6 -1.5 phosphopantothenate/pantothenate synthetase compare
MMP_RS03435 -1.6 -1.2 ketol-acid reductoisomerase compare
MMP_RS01220 -1.6 -6.9 hypothetical protein compare
MMP_RS06230 -1.6 -1.9 helix-turn-helix domain-containing protein compare
MMP_RS01795 -1.6 -1.2 methanogenesis marker 6 protein compare
MMP_RS07730 -1.6 -1.4 pyruvate synthase subunit beta compare
MMP_RS00040 -1.6 -4.7 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS05640 -1.6 -4.8 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS02010 -1.6 -7.2 PHP domain-containing protein compare
MMP_RS01270 -1.6 -10.3 prepilin peptidase compare
MMP_RS03140 -1.6 -6.0 hypothetical protein compare
MMP_RS06725 -1.6 -7.2 hypothetical protein compare
MMP_RS06895 -1.6 -1.2 selenocysteine-specific translation elongation factor compare
MMP_RS01280 -1.6 -11.0 DUF515 domain-containing protein compare
MMP_RS01500 -1.6 -1.5 CBS domain-containing protein compare
MMP_RS03440 -1.6 -0.9 MoaD/ThiS family protein compare
MMP_RS09020 -1.6 -1.2 hypothetical protein compare
MMP_RS07355 -1.6 -0.7 transcription factor S compare
MMP_RS07600 -1.5 -1.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01650 -1.5 -0.6 sulfurtransferase TusA family protein compare
MMP_RS00320 -1.5 -1.5 class I SAM-dependent methyltransferase compare
MMP_RS02175 -1.5 -0.6 DUF1611 domain-containing protein compare
MMP_RS05635 -1.5 -7.9 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS03250 -1.5 -3.6 MJ1244 family protein compare
MMP_RS07875 -1.5 -3.5 hypothetical protein compare
MMP_RS03015 -1.5 -7.7 GTP 3' 8-cyclase MoaA compare
MMP_RS04955 -1.5 -5.2 DNA topoisomerase I compare
MMP_RS00245 -1.5 -11.9 type II secretion system F family protein compare
MMP_RS05430 -1.5 -4.4 TIGR00288 family NYN domain-containing protein compare
MMP_RS07330 -1.5 -10.4 membrane protein compare
MMP_RS04775 -1.5 -2.7 adenosylhomocysteinase compare
MMP_RS01325 -1.5 -1.3 dihydroneopterin aldolase family protein compare
MMP_RS01305 -1.5 -11.5 hypothetical protein compare
MMP_RS06020 -1.5 -3.1 archaeoflavoprotein AfpA compare
MMP_RS00250 -1.5 -11.0 Flp pilus assembly complex ATPase component TadA compare
MMP_RS00240 -1.5 -10.5 type II secretion system F family protein compare
MMP_RS06035 -1.5 -8.2 glycosyltransferase family 2 protein compare
MMP_RS06310 -1.5 -3.5 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS03125 -1.5 -4.3 cell division ATPase MinD compare
MMP_RS07695 -1.5 -5.1 DUF3236 domain-containing protein compare
MMP_RS01890 -1.5 -3.0 nucleotide sugar dehydrogenase compare
MMP_RS03475 -1.5 -0.4 hypothetical protein compare
MMP_RS02235 -1.5 -7.5 CBS domain-containing protein compare
MMP_RS00750 -1.5 -1.8 fumarate hydratase compare
MMP_RS07545 -1.4 -0.8 HTH domain-containing protein compare
MMP_RS07350 -1.4 -1.4 preprotein translocase subunit Sec61beta compare
MMP_RS05580 -1.4 -10.7 glycosyltransferase compare
MMP_RS01295 -1.4 -7.8 hypothetical protein compare
MMP_RS02345 -1.4 -2.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05345 -1.4 -6.6 hypothetical protein compare
MMP_RS05535 -1.4 -4.1 hypothetical protein compare
MMP_RS05555 -1.4 -1.1 DUF4040 domain-containing protein compare
MMP_RS07735 -1.4 -0.5 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS01830 -1.4 -1.1 tRNA-Val compare
MMP_RS01285 -1.4 -7.4 hypothetical protein compare
MMP_RS03080 -1.4 -2.2 universal stress protein compare
MMP_RS01290 -1.4 -7.3 class III signal peptide-containing protein compare
MMP_RS07445 -1.4 -5.1 helix-turn-helix domain-containing protein compare
MMP_RS01905 -1.4 -7.8 glycosyltransferase compare
MMP_RS08855 -1.4 -7.8 hypothetical protein compare
MMP_RS03390 -1.4 -5.6 malate dehydrogenase compare
MMP_RS01310 -1.3 -10.1 hypothetical protein compare
MMP_RS01315 -1.3 -11.5 DUF2341 domain-containing protein compare
MMP_RS07525 -1.3 -5.1 4Fe-4S binding protein compare
MMP_RS08860 -1.3 -4.6 MinD/ParA family protein compare
MMP_RS05515 -1.3 -5.5 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS04485 -1.3 -6.1 putative beta-lysine N-acetyltransferase compare
MMP_RS09055 -1.3 -0.8 CAP domain-containing protein compare
MMP_RS07540 -1.3 -2.5 CBS domain-containing protein compare
MMP_RS03095 -1.3 -4.2 diphthine synthase compare
MMP_RS01900 -1.3 -7.3 hypothetical protein compare
MMP_RS01925 -1.3 -5.8 DUF1616 domain-containing protein compare
MMP_RS00725 -1.3 -4.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04090 -1.3 -2.0 hypothetical protein compare
MMP_RS07710 -1.3 -4.9 cell division protein FtsZ compare
MMP_RS07380 -1.3 -1.5 transcription elongation factor Spt5 compare
MMP_RS00515 -1.3 -0.7 DUF655 domain-containing protein compare
MMP_RS08195 -1.3 -6.2 hypothetical protein compare
MMP_RS06980 -1.3 -4.2 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS01020 -1.3 -0.7 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01915 -1.3 -6.3 DUF354 domain-containing protein compare
MMP_RS00735 -1.2 -2.9 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS02355 -1.2 -1.6 30S ribosomal protein S27ae compare
MMP_RS07820 -1.2 -2.8 UPF0104 family protein compare
MMP_RS01275 -1.2 -5.6 class III signal peptide-containing protein compare
MMP_RS03960 -1.2 -0.7 hypothetical protein compare
MMP_RS01960 -1.2 -0.6 hypothetical protein compare
MMP_RS07385 -1.2 -1.1 protein translocase SEC61 complex subunit gamma compare
MMP_RS09045 -1.2 -8.7 class III signal peptide-containing protein compare
MMP_RS07575 -1.2 -1.8 RNA ligase partner protein compare
MMP_RS01380 -1.2 -2.5 PHP domain-containing protein compare
MMP_RS06865 -1.2 -1.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS07625 -1.2 -2.2 cobalt ECF transporter T component CbiQ compare
MMP_RS01725 -1.1 -2.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS04360 -1.1 -2.9 hypothetical protein compare
MMP_RS02930 -1.1 -1.9 class I SAM-dependent methyltransferase compare
MMP_RS06400 -1.1 -0.7 4Fe-4S binding protein compare
MMP_RS08635 -1.1 -1.0 UbiA family prenyltransferase compare
MMP_RS06525 -1.1 -0.8 YciI family protein compare
MMP_RS06630 -1.1 -0.5 UPF0058 family protein compare
MMP_RS06670 -1.1 -2.4 glucose-6-phosphate isomerase compare
MMP_RS08940 -1.1 -1.0 MetS family NSS transporter small subunit compare
MMP_RS05280 -1.1 -5.1 COG1361 S-layer family protein compare
MMP_RS08715 -1.1 -1.0 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06105 -1.1 -4.4 hydrogenase maturation peptidase HycI compare
MMP_RS08330 -1.1 -3.9 NADH-quinone oxidoreductase subunit H compare
MMP_RS00685 -1.1 -1.8 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06530 -1.1 -3.1 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS02290 -1.1 -5.2 MBL fold metallo-hydrolase compare
MMP_RS00140 -1.1 -4.0 DUF192 domain-containing protein compare
MMP_RS02955 -1.1 -2.2 DJ-1/PfpI family protein compare
MMP_RS01910 -1.0 -3.4 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS04615 -1.0 -1.9 PDGLE domain-containing protein compare
MMP_RS04850 -1.0 -6.9 UPF0254 family protein compare
MMP_RS01745 -1.0 -3.0 AMP phosphorylase compare
MMP_RS02280 -1.0 -0.4 DUF211 domain-containing protein compare
MMP_RS04695 -1.0 -3.3 selenide water dikinase SelD compare
MMP_RS06855 -1.0 -4.0 hypothetical protein compare
MMP_RS01195 -1.0 -0.9 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06485 -1.0 -0.6 zinc ribbon domain-containing protein compare
MMP_RS07555 -1.0 -0.4 monovalent cation/H+ antiporter subunit E compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Anhydrotetracycline hydrochloride across organisms