Experiment set11S231 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Sulfaquinoxaline sodium salt 0.1 mM

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS04875 +3.3 10.8 energy-converting hydrogenase B subunit P compare
MMP_RS08350 +2.5 1.9 hypothetical protein compare
MMP_RS02605 +2.4 2.3 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS05925 +2.4 5.7 small nuclear ribonucleoprotein compare
MMP_RS07345 +2.2 6.1 glycine synthesis protein GlyXL (from data) compare
MMP_RS01940 +2.2 2.4 MoxR family ATPase compare
MMP_RS02410 +2.0 3.4 ABC transporter substrate-binding protein compare
MMP_RS01335 +2.0 3.8 prefoldin subunit beta compare
MMP_RS07850 +1.9 3.3 prephenate dehydratase compare
MMP_RS06485 +1.9 1.7 zinc ribbon domain-containing protein compare
MMP_RS06325 +1.9 2.3 hypothetical protein compare
MMP_RS00945 +1.8 2.0 PadR family transcriptional regulator compare
MMP_RS07815 +1.8 2.3 DUF2120 domain-containing protein compare
MMP_RS08360 +1.7 4.1 hypothetical protein compare
MMP_RS05850 +1.7 2.9 Ldh family oxidoreductase compare
MMP_RS06860 +1.7 2.6 4Fe-4S binding protein compare
MMP_RS08310 +1.6 2.6 TMEM165/GDT1 family protein compare
MMP_RS06705 +1.6 5.0 formate/nitrite transporter family protein compare
MMP_RS08000 +1.6 8.1 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS08445 +1.5 2.8 DUF2099 family protein compare
MMP_RS05950 +1.5 5.8 nickel-dependent hydrogenase large subunit compare
MMP_RS03340 +1.5 1.2 ABC transporter ATP-binding protein compare
MMP_RS08370 +1.5 0.9 cation:proton antiporter subunit C compare
MMP_RS07435 +1.4 1.5 GMP synthase subunit A compare
MMP_RS08980 +1.4 2.8 hypothetical protein compare
MMP_RS01650 +1.4 1.0 sulfurtransferase TusA family protein compare
MMP_RS01830 +1.4 1.3 tRNA-Val compare
MMP_RS00120 +1.4 3.0 LysR family transcriptional regulator compare
MMP_RS02245 +1.3 2.8 hypothetical protein compare
MMP_RS05425 +1.3 4.0 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS06015 +1.3 5.2 flavodoxin family protein compare
MMP_RS05975 +1.3 4.7 hypothetical protein compare
MMP_RS01330 +1.3 5.1 DHH family phosphoesterase compare
MMP_RS08240 +1.3 2.8 methanogenesis marker 16 metalloprotein compare
MMP_RS08390 +1.2 2.6 DUF5400 domain-containing protein compare
MMP_RS08775 +1.2 3.7 methanogenesis marker 9 domain-containing protein compare
MMP_RS08340 +1.2 3.3 4Fe-4S binding protein compare
MMP_RS00060 +1.2 1.5 3-dehydroquinate synthase II compare
MMP_RS01570 +1.2 1.3 hypothetical protein compare
MMP_RS00735 +1.2 3.9 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS06010 +1.2 5.2 heavy metal translocating P-type ATPase compare
MMP_RS02790 +1.1 1.0 class III signal peptide-containing protein compare
MMP_RS08365 +1.1 2.8 energy conserving hydrogenase EhbF compare
MMP_RS08750 +1.1 1.6 hypothetical protein compare
MMP_RS08355 +1.1 2.9 Na(+)/H(+) antiporter subunit B compare
MMP_RS00900 +1.1 1.4 50S ribosomal protein L39e compare
MMP_RS02870 +1.1 2.9 hypothetical protein compare
MMP_RS01430 +1.1 3.2 mechanosensitive ion channel family protein compare
MMP_RS07415 +1.1 4.2 molybdopterin-guanine dinucleotide biosynthesis protein MobB compare
MMP_RS08335 +1.1 2.9 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS07355 +1.1 0.9 transcription factor S compare
MMP_RS06005 +1.1 3.1 heavy-metal-associated domain-containing protein compare
MMP_RS07700 +1.0 4.2 DUF1188 domain-containing protein compare
MMP_RS02675 +1.0 1.3 hypothetical protein compare
MMP_RS03910 +1.0 1.0 hypothetical protein compare
MMP_RS05700 +1.0 3.6 TfuA-related McrA-glycine thioamidation protein compare
MMP_RS03450 +1.0 1.2 glycine synthesis protein GlyXS (from data) compare
MMP_RS00530 +0.9 2.3 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS00650 +0.9 2.6 ABC transporter ATP-binding protein compare
MMP_RS03535 +0.9 1.1 helix-turn-helix transcriptional regulator compare
MMP_RS06395 +0.9 0.7 ThiF family adenylyltransferase compare
MMP_RS08275 +0.9 3.5 hypothetical protein compare
MMP_RS05665 +0.9 1.6 phosphate ABC transporter permease subunit PstC compare
MMP_RS08345 +0.9 3.5 4Fe-4S binding protein compare
MMP_RS03465 +0.9 0.8 adenine phosphoribosyltransferase compare
MMP_RS01180 +0.9 1.3 XTP/dITP diphosphatase compare
MMP_RS05505 +0.9 3.7 class IV adenylate cyclase compare
MMP_RS03520 +0.9 1.4 YwbE family protein compare
MMP_RS01920 +0.8 2.8 glycosyltransferase family 2 protein compare
MMP_RS08670 +0.8 2.5 metallophosphoesterase compare
MMP_RS03430 +0.8 3.5 bile acid:sodium symporter family protein compare
MMP_RS02045 +0.8 0.9 tRNA-Met compare
MMP_RS07835 +0.8 2.0 TldD/PmbA family protein compare
MMP_RS06155 +0.8 1.5 DUF4186 domain-containing protein compare
MMP_RS06165 +0.8 2.2 ABC transporter permease compare
MMP_RS07155 +0.8 2.4 MFS transporter compare
MMP_RS06335 +0.8 1.6 HAD family hydrolase compare
MMP_RS07890 +0.8 1.3 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS08325 +0.8 3.0 hypothetical protein compare
MMP_RS03585 +0.7 1.5 Hsp20/alpha crystallin family protein compare
MMP_RS05875 +0.7 1.7 hydroxyethylthiazole kinase compare
MMP_RS08500 +0.7 1.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS02740 +0.7 1.4 hypothetical protein compare
MMP_RS08215 +0.7 0.7 DUF483 domain-containing protein compare
MMP_RS00125 +0.7 0.8 DUF2798 domain-containing protein compare
MMP_RS01055 +0.7 2.1 hypothetical protein compare
MMP_RS01930 +0.7 3.0 hypothetical protein compare
MMP_RS00345 +0.7 1.1 DUF2666 domain-containing protein compare
MMP_RS06095 +0.7 1.5 ABC transporter ATP-binding protein compare
MMP_RS01320 +0.7 1.4 hypothetical protein compare
MMP_RS01980 +0.7 3.6 trimeric intracellular cation channel family protein compare
MMP_RS00395 +0.6 0.8 MGMT family protein compare
MMP_RS04480 +0.6 2.3 lysine 2 3-aminomutase compare
MMP_RS02895 +0.6 2.5 DHH family phosphoesterase compare
MMP_RS06480 +0.6 1.4 ABC transporter substrate-binding protein compare
MMP_RS04945 +0.6 2.2 hypothetical protein compare
MMP_RS01965 +0.6 1.9 DUF1616 domain-containing protein compare
MMP_RS05065 +0.6 0.9 CooT family nickel-binding protein compare
MMP_RS01935 +0.6 1.7 DUF58 domain-containing protein compare
MMP_RS06745 +0.6 1.3 DUF2119 domain-containing protein compare
MMP_RS05825 +0.6 2.1 peptidyl-prolyl cis-trans isomerase compare
MMP_RS05835 +0.6 0.3 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS08330 +0.6 1.6 NADH-quinone oxidoreductase subunit H compare
MMP_RS00770 +0.6 1.7 hypothetical protein compare
MMP_RS00980 +0.6 2.0 hypothetical protein compare
MMP_RS01460 +0.6 1.7 hypothetical protein compare
MMP_RS01150 +0.6 1.1 aldo/keto reductase compare
MMP_RS07650 +0.6 2.5 TldD/PmbA family protein compare
MMP_RS08385 +0.6 1.3 ABC transporter substrate-binding protein compare
MMP_RS05485 +0.6 2.8 cysteine--tRNA ligase compare
MMP_RS05510 +0.6 2.7 Rrf2 family transcriptional regulator compare
MMP_RS07535 +0.6 1.9 4Fe-4S binding protein compare
MMP_RS02890 +0.6 1.7 TIGR00296 family protein compare
MMP_RS05675 +0.6 0.8 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS08575 +0.5 2.6 hypothetical protein compare
MMP_RS01415 +0.5 1.0 DUF2067 domain-containing protein compare
MMP_RS01910 +0.5 1.9 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS06915 +0.5 1.5 metallophosphoesterase compare
MMP_RS06680 +0.5 2.4 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS04870 +0.5 1.3 TIGR02253 family HAD-type hydrolase compare
MMP_RS07725 +0.5 1.5 4Fe-4S dicluster domain-containing protein compare
MMP_RS08630 +0.5 2.0 archaellar assembly protein FlaJ compare
MMP_RS08290 +0.5 1.2 DNA-binding protein Alba compare
MMP_RS05440 +0.5 1.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS08580 +0.5 1.0 flagellin compare
MMP_RS01630 +0.5 1.5 N-glycosylase/DNA lyase compare
MMP_RS07180 +0.5 2.1 DEAD/DEAH box helicase compare
MMP_RS06070 +0.5 2.2 iron ABC transporter substrate-binding protein compare
MMP_RS01420 +0.5 0.5 hypothetical protein compare
MMP_RS05985 +0.5 0.6 hypothetical protein compare
MMP_RS01950 +0.5 1.8 hypothetical protein compare
MMP_RS03870 +0.5 1.5 purine NTPase compare
MMP_RS08455 +0.5 0.6 multiprotein bridging factor aMBF1 compare
MMP_RS01540 +0.5 0.5 DUF504 domain-containing protein compare
MMP_RS07840 +0.5 0.6 ribonuclease III compare
MMP_RS03495 +0.5 1.7 Na/Pi cotransporter family protein compare
MMP_RS00380 +0.5 1.0 P-II family nitrogen regulator compare
MMP_RS06495 +0.5 1.1 YkgJ family cysteine cluster protein compare
MMP_RS06175 +0.5 1.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS01750 +0.5 1.8 DUF63 family protein compare
MMP_RS00940 +0.5 1.3 daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein compare
MMP_RS00430 +0.5 0.9 hypothetical protein compare
MMP_RS05460 +0.5 2.6 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS03205 +0.5 0.4 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS03790 +0.5 1.6 hypothetical protein compare
MMP_RS02390 +0.5 1.5 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS01970 +0.5 1.8 TIGR04279 domain-containing protein compare
MMP_RS04595 +0.5 0.9 hypothetical protein compare
MMP_RS02475 +0.5 1.3 hypothetical protein compare
MMP_RS05450 +0.5 1.0 CoB--CoM heterodisulfide reductase subunit C compare
MMP_RS06685 +0.5 2.0 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01475 +0.5 1.3 phosphosulfolactate synthase compare
MMP_RS08850 +0.5 2.5 hypothetical protein compare
MMP_RS07645 +0.5 1.1 aldehyde dehydrogenase family protein compare
MMP_RS02310 +0.5 0.5 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS06920 +0.5 2.1 AAA family ATPase compare
MMP_RS00290 +0.4 0.9 hypothetical protein compare
MMP_RS00710 +0.4 1.2 hypothetical protein compare
MMP_RS01550 +0.4 1.3 DUF1624 domain-containing protein compare
MMP_RS07905 +0.4 1.8 DUF3343 domain-containing protein compare
MMP_RS00725 +0.4 0.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS02765 +0.4 1.1 ABC transporter ATP-binding protein compare
MMP_RS04835 +0.4 2.1 chemotaxis protein CheC compare
MMP_RS03735 +0.4 1.8 indolepyruvate ferredoxin oxidoreductase subunit alpha compare
MMP_RS04530 +0.4 1.5 ABC transporter permease compare
MMP_RS01110 +0.4 0.5 FmdE family protein compare
MMP_RS06140 +0.4 1.1 radical SAM protein compare
MMP_RS01190 +0.4 0.8 cadmium-translocating P-type ATPase compare
MMP_RS07195 +0.4 1.8 M20 family metallo-hydrolase compare
MMP_RS06500 +0.4 1.7 ATP-binding protein compare
MMP_RS08930 +0.4 0.3 hypothetical protein compare
MMP_RS07640 +0.4 1.1 mechanosensitive ion channel family protein compare
MMP_RS04435 +0.4 1.9 pyridoxamine 5'-phosphate oxidase family protein compare
MMP_RS00990 +0.4 1.1 hypothetical protein compare
MMP_RS01780 +0.4 1.3 TrmJ/YjtD family RNA methyltransferase compare
MMP_RS07100 +0.4 1.6 hypothetical protein compare
MMP_RS05310 +0.4 1.1 hypothetical protein compare
MMP_RS07085 +0.4 1.1 ribonuclease HII compare
MMP_RS03670 +0.4 0.7 DUF1890 domain-containing protein compare
MMP_RS07530 +0.4 1.4 4Fe-4S binding protein compare
MMP_RS02295 +0.4 1.5 TatD family hydrolase compare
MMP_RS08705 +0.4 1.1 sulfopyruvate decarboxylase subunit beta compare
MMP_RS00730 +0.4 0.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS06060 +0.4 1.5 hypothetical protein compare
MMP_RS05660 +0.4 1.3 phosphate ABC transporter substrate-binding protein compare
MMP_RS01240 +0.4 0.3 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS06215 +0.4 0.4 30S ribosomal protein S6e compare
MMP_RS04895 +0.4 2.3 AI-2E family transporter compare
MMP_RS06575 +0.4 1.1 fluoride efflux transporter CrcB compare
MMP_RS05490 +0.4 0.9 IMPACT family protein compare
MMP_RS00155 +0.4 1.4 heavy metal-binding domain-containing protein compare
MMP_RS05895 +0.4 1.5 metallophosphoesterase compare
MMP_RS09060 +0.4 1.6 hypothetical protein compare
MMP_RS01765 +0.4 1.6 HIT family protein compare
MMP_RS01105 +0.4 1.1 hypothetical protein compare
MMP_RS06225 +0.4 1.2 DNA double-strand break repair nuclease NurA compare
MMP_RS07925 +0.4 0.8 haloacid dehalogenase compare
MMP_RS01435 +0.4 0.8 DMT family transporter compare
MMP_RS02380 +0.4 1.2 ATP-binding protein compare
MMP_RS08555 +0.4 0.6 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress Sulfaquinoxaline sodium salt in Methanococcus maripaludis S2

For stress Sulfaquinoxaline sodium salt across organisms