Experiment set11S229 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete 8-hydroxy-nitroquinolone 0.0166666666666667 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS06120 -5.5 -1.6 UPF0147 family protein compare
MMP_RS08715 -5.5 -1.6 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06895 -5.1 -1.5 selenocysteine-specific translation elongation factor compare
MMP_RS04890 -4.2 -0.6 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS07545 -4.0 -0.8 HTH domain-containing protein compare
MMP_RS00300 -4.0 -0.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06730 -3.9 -1.8 phosphopantothenate/pantothenate synthetase compare
MMP_RS04720 -3.7 -2.6 DedA family protein compare
MMP_RS01960 -3.6 -0.7 hypothetical protein compare
MMP_RS08440 -3.5 -2.4 cell division protein SepF compare
MMP_RS02900 -3.5 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS02145 -3.5 -8.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS09020 -3.5 -1.3 hypothetical protein compare
MMP_RS07355 -3.4 -0.8 transcription factor S compare
MMP_RS01265 -3.3 -2.6 hypothetical protein compare
MMP_RS07635 -3.2 -5.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS04710 -3.2 -1.7 hypothetical protein compare
MMP_RS03445 -3.1 -0.8 methanogenesis marker 17 protein compare
MMP_RS06350 -3.0 -6.7 HesA/MoeB/ThiF family protein compare
MMP_RS07845 -3.0 -2.5 LL-diaminopimelate aminotransferase compare
MMP_RS00305 -2.9 -1.4 phosphoribosyl-ATP diphosphatase compare
MMP_RS04900 -2.9 -19.4 hypothetical protein compare
MMP_RS03475 -2.8 -0.5 hypothetical protein compare
MMP_RS06355 -2.8 -2.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03315 -2.7 -1.1 ferrous iron transport protein A compare
MMP_RS00515 -2.7 -0.8 DUF655 domain-containing protein compare
MMP_RS01225 -2.7 -4.2 DUF5379 domain-containing protein compare
MMP_RS08300 -2.7 -1.0 metal-sulfur cluster assembly factor compare
MMP_RS05550 -2.6 -0.7 cation:proton antiporter compare
MMP_RS03580 -2.6 -3.1 signal recognition particle-docking protein FtsY compare
MMP_RS02800 -2.6 -7.8 nucleotidyltransferase domain-containing protein compare
MMP_RS07600 -2.6 -1.5 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06295 -2.5 -7.3 methanogenesis marker 14 protein compare
MMP_RS03025 -2.5 -4.1 molybdenum cofactor guanylyltransferase compare
MMP_RS01545 -2.4 -0.8 CBS domain-containing protein compare
MMP_RS01175 -2.4 -3.4 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS03250 -2.4 -3.6 MJ1244 family protein compare
MMP_RS01380 -2.4 -3.9 PHP domain-containing protein compare
MMP_RS02290 -2.4 -5.8 MBL fold metallo-hydrolase compare
MMP_RS08650 -2.3 -2.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07555 -2.3 -0.6 monovalent cation/H+ antiporter subunit E compare
MMP_RS08635 -2.3 -1.3 UbiA family prenyltransferase compare
MMP_RS00725 -2.3 -5.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06340 -2.3 -5.5 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS03700 -2.3 -6.9 sodium:proton antiporter compare
MMP_RS01745 -2.3 -7.1 AMP phosphorylase compare
MMP_RS06285 -2.3 -1.8 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS02235 -2.2 -7.7 CBS domain-containing protein compare
MMP_RS02875 -2.2 -6.8 chorismate pyruvate-lyase family protein compare
MMP_RS01270 -2.2 -12.6 prepilin peptidase compare
MMP_RS00520 -2.2 -1.3 RNA polymerase Rpb4 family protein compare
MMP_RS01665 -2.2 -4.1 DUF2111 domain-containing protein compare
MMP_RS07695 -2.2 -4.7 DUF3236 domain-containing protein compare
MMP_RS01755 -2.2 -1.1 DUF2097 domain-containing protein compare
MMP_RS01900 -2.2 -11.3 hypothetical protein compare
MMP_RS05835 -2.1 -0.5 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS06395 -2.1 -2.5 ThiF family adenylyltransferase compare
MMP_RS06315 -2.1 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS04685 -2.1 -2.1 DUF126 domain-containing protein compare
MMP_RS01830 -2.1 -1.2 tRNA-Val compare
MMP_RS00250 -2.1 -14.8 Flp pilus assembly complex ATPase component TadA compare
MMP_RS01875 -2.1 -6.4 N-acetyltransferase compare
MMP_RS02240 -2.1 -2.2 methanogenesis marker 7 protein compare
MMP_RS03640 -2.1 -3.0 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06400 -2.1 -1.0 4Fe-4S binding protein compare
MMP_RS03400 -2.1 -1.5 archease compare
MMP_RS08675 -2.1 -2.5 class III signal peptide-containing protein compare
MMP_RS05515 -2.1 -5.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS01925 -2.1 -5.1 DUF1616 domain-containing protein compare
MMP_RS08820 -2.0 -4.8 hypothetical protein compare
MMP_RS07005 -2.0 -0.5 4Fe-4S binding protein compare
MMP_RS08745 -2.0 -4.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06035 -2.0 -7.6 glycosyltransferase family 2 protein compare
MMP_RS03110 -2.0 -4.3 glycosyltransferase family 2 protein compare
MMP_RS01575 -2.0 -5.6 aldolase compare
MMP_RS06625 -2.0 -1.3 DNA primase compare
MMP_RS07730 -2.0 -1.5 pyruvate synthase subunit beta compare
MMP_RS07420 -2.0 -4.5 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS05635 -2.0 -7.5 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS04850 -2.0 -12.1 UPF0254 family protein compare
MMP_RS08720 -2.0 -1.0 4Fe-4S binding protein compare
MMP_RS01310 -2.0 -12.2 hypothetical protein compare
MMP_RS06630 -2.0 -0.6 UPF0058 family protein compare
MMP_RS08435 -2.0 -1.7 Era-like GTP-binding protein compare
MMP_RS03015 -2.0 -7.9 GTP 3' 8-cyclase MoaA compare
MMP_RS00240 -2.0 -12.3 type II secretion system F family protein compare
MMP_RS05640 -2.0 -5.2 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS02195 -2.0 -3.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05555 -2.0 -1.1 DUF4040 domain-containing protein compare
MMP_RS01610 -1.9 -2.5 hypothetical protein compare
MMP_RS01500 -1.9 -1.2 CBS domain-containing protein compare
MMP_RS00245 -1.9 -15.0 type II secretion system F family protein compare
MMP_RS03080 -1.9 -2.2 universal stress protein compare
MMP_RS07820 -1.9 -4.1 UPF0104 family protein compare
MMP_RS05425 -1.9 -3.1 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS01905 -1.9 -8.8 glycosyltransferase compare
MMP_RS00985 -1.9 -4.0 CDC48 family AAA ATPase compare
MMP_RS01280 -1.9 -11.3 DUF515 domain-containing protein compare
MMP_RS06600 -1.9 -0.9 class III signal peptide-containing protein compare
MMP_RS07330 -1.9 -12.3 membrane protein compare
MMP_RS01385 -1.9 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06105 -1.9 -7.7 hydrogenase maturation peptidase HycI compare
MMP_RS07075 -1.9 -2.9 phosphomannomutase/phosphoglucomutase compare
MMP_RS08195 -1.9 -7.9 hypothetical protein compare
MMP_RS00110 -1.8 -2.1 hypothetical protein compare
MMP_RS00040 -1.8 -4.5 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01325 -1.8 -1.4 dihydroneopterin aldolase family protein compare
MMP_RS06725 -1.8 -6.6 hypothetical protein compare
MMP_RS01220 -1.8 -5.0 hypothetical protein compare
MMP_RS05580 -1.8 -11.7 glycosyltransferase compare
MMP_RS01295 -1.8 -9.8 hypothetical protein compare
MMP_RS02345 -1.8 -2.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS08855 -1.7 -8.6 hypothetical protein compare
MMP_RS07955 -1.7 -4.0 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS00810 -1.7 -6.3 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07605 -1.7 -1.9 diadenylate cyclase compare
MMP_RS03600 -1.7 -1.3 triose-phosphate isomerase compare
MMP_RS01305 -1.7 -12.3 hypothetical protein compare
MMP_RS01195 -1.7 -1.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01315 -1.7 -13.6 DUF2341 domain-containing protein compare
MMP_RS04695 -1.7 -4.9 selenide water dikinase SelD compare
MMP_RS08915 -1.7 -2.5 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS07380 -1.7 -1.3 transcription elongation factor Spt5 compare
MMP_RS00115 -1.6 -7.2 radical SAM protein compare
MMP_RS08210 -1.6 -1.6 phosphatidylglycerophosphatase A compare
MMP_RS01290 -1.6 -7.8 class III signal peptide-containing protein compare
MMP_RS08790 -1.6 -1.0 translation initiation factor IF-2 subunit alpha compare
MMP_RS00735 -1.6 -2.0 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS08155 -1.6 -4.8 hypothetical protein compare
MMP_RS06020 -1.6 -2.4 archaeoflavoprotein AfpA compare
MMP_RS08370 -1.6 -0.4 cation:proton antiporter subunit C compare
MMP_RS06885 -1.6 -1.9 50S ribosome-binding GTPase compare
MMP_RS07390 -1.6 -1.4 cell division protein FtsZ compare
MMP_RS05920 -1.5 -0.4 50S ribosomal protein L37e compare
MMP_RS03960 -1.5 -0.7 hypothetical protein compare
MMP_RS07750 -1.5 -3.7 DUF357 domain-containing protein compare
MMP_RS03120 -1.5 -2.2 hypothetical protein compare
MMP_RS04955 -1.5 -4.8 DNA topoisomerase I compare
MMP_RS06485 -1.5 -0.6 zinc ribbon domain-containing protein compare
MMP_RS04615 -1.5 -1.8 PDGLE domain-containing protein compare
MMP_RS00895 -1.5 -2.1 hypothetical protein compare
MMP_RS01880 -1.5 -3.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS03125 -1.5 -3.3 cell division ATPase MinD compare
MMP_RS04780 -1.5 -1.7 ribonuclease P compare
MMP_RS01285 -1.4 -6.8 hypothetical protein compare
MMP_RS08330 -1.4 -3.7 NADH-quinone oxidoreductase subunit H compare
MMP_RS01800 -1.4 -2.9 TIGR00303 family protein compare
MMP_RS00730 -1.4 -3.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS05695 -1.4 -4.3 phospholipase D-like domain-containing protein compare
MMP_RS06900 -1.4 -1.9 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01020 -1.4 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS05850 -1.4 -3.3 Ldh family oxidoreductase compare
MMP_RS07575 -1.4 -2.4 RNA ligase partner protein compare
MMP_RS07700 -1.4 -5.8 DUF1188 domain-containing protein compare
MMP_RS05345 -1.4 -4.5 hypothetical protein compare
MMP_RS05540 -1.4 -2.2 hypothetical protein compare
MMP_RS00750 -1.4 -1.5 fumarate hydratase compare
MMP_RS05245 -1.4 -5.6 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS07425 -1.4 -3.3 GTP-binding protein compare
MMP_RS00315 -1.4 -4.1 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS06270 -1.3 -2.9 TIGR00300 family protein compare
MMP_RS01795 -1.3 -0.8 methanogenesis marker 6 protein compare
MMP_RS00915 -1.3 -4.0 DUF116 domain-containing protein compare
MMP_RS01085 -1.3 -1.3 hypothetical protein compare
MMP_RS03435 -1.3 -1.0 ketol-acid reductoisomerase compare
MMP_RS01275 -1.3 -5.1 class III signal peptide-containing protein compare
MMP_RS03145 -1.3 -3.8 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS05430 -1.3 -3.5 TIGR00288 family NYN domain-containing protein compare
MMP_RS06675 -1.3 -4.0 ADP-specific phosphofructokinase compare
MMP_RS08860 -1.3 -3.4 MinD/ParA family protein compare
MMP_RS09055 -1.3 -0.7 CAP domain-containing protein compare
MMP_RS06475 -1.3 -2.3 FAD-dependent oxidoreductase compare
MMP_RS02245 -1.3 -2.2 hypothetical protein compare
MMP_RS00685 -1.2 -2.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01895 -1.2 -6.6 flippase compare
MMP_RS03390 -1.2 -3.9 malate dehydrogenase compare
MMP_RS05965 -1.2 -1.6 carboxymuconolactone decarboxylase family protein compare
MMP_RS04585 -1.2 -5.0 AIR synthase related protein compare
MMP_RS00720 -1.2 -4.0 metal-dependent hydrolase compare
MMP_RS09045 -1.2 -6.9 class III signal peptide-containing protein compare
MMP_RS06980 -1.2 -4.3 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS07445 -1.2 -3.7 helix-turn-helix domain-containing protein compare
MMP_RS06670 -1.2 -2.6 glucose-6-phosphate isomerase compare
MMP_RS01700 -1.2 -0.6 dihydroxy-acid dehydratase compare
MMP_RS04090 -1.2 -1.8 hypothetical protein compare
MMP_RS01335 -1.2 -1.1 prefoldin subunit beta compare
MMP_RS02265 -1.2 -2.3 nitroreductase family protein compare
MMP_RS00320 -1.2 -1.1 class I SAM-dependent methyltransferase compare
MMP_RS05845 -1.2 -0.9 tRNA-intron lyase compare
MMP_RS07200 -1.2 -3.3 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS07710 -1.2 -2.3 cell division protein FtsZ compare
MMP_RS01725 -1.2 -1.8 class I SAM-dependent methyltransferase family protein compare
MMP_RS03385 -1.2 -0.6 cation diffusion facilitator family transporter compare
MMP_RS07540 -1.2 -2.4 CBS domain-containing protein compare
MMP_RS03095 -1.1 -3.7 diphthine synthase compare
MMP_RS01005 -1.1 -0.8 riboflavin synthase compare
MMP_RS05815 -1.1 -0.5 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07755 -1.1 -0.7 DUF555 domain-containing protein compare
MMP_RS07350 -1.1 -1.2 preprotein translocase subunit Sec61beta compare
MMP_RS02010 -1.0 -2.7 PHP domain-containing protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress 8-hydroxy-nitroquinolone across organisms