Experiment set11S213 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete metronidazole 0.000833333333333333

200 most important genes:

  gene name fitness t score description  
MMP_RS06120 -6.5 -1.1 UPF0147 family protein compare
MMP_RS05550 -5.7 -0.5 cation:proton antiporter compare
MMP_RS01755 -5.5 -0.7 DUF2097 domain-containing protein compare
MMP_RS03400 -5.3 -1.8 archease compare
MMP_RS03315 -5.3 -0.8 ferrous iron transport protein A compare
MMP_RS00300 -5.3 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS02900 -4.9 -0.4 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07005 -4.9 -0.4 4Fe-4S binding protein compare
MMP_RS01500 -4.7 -1.3 CBS domain-containing protein compare
MMP_RS06895 -4.7 -1.2 selenocysteine-specific translation elongation factor compare
MMP_RS05920 -4.6 -0.4 50S ribosomal protein L37e compare
MMP_RS08715 -4.4 -1.3 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01545 -4.3 -0.7 CBS domain-containing protein compare
MMP_RS02240 -4.2 -2.4 methanogenesis marker 7 protein compare
MMP_RS07390 -4.0 -1.9 cell division protein FtsZ compare
MMP_RS08635 -3.7 -1.1 UbiA family prenyltransferase compare
MMP_RS08370 -3.6 -0.5 cation:proton antiporter subunit C compare
MMP_RS03445 -3.6 -0.6 methanogenesis marker 17 protein compare
MMP_RS03435 -3.5 -1.2 ketol-acid reductoisomerase compare
MMP_RS07735 -3.5 -0.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08650 -3.4 -2.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01325 -3.4 -1.3 dihydroneopterin aldolase family protein compare
MMP_RS02145 -3.3 -6.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS08720 -3.3 -1.1 4Fe-4S binding protein compare
MMP_RS01225 -3.2 -4.0 DUF5379 domain-containing protein compare
MMP_RS07845 -3.2 -2.3 LL-diaminopimelate aminotransferase compare
MMP_RS01380 -3.2 -3.6 PHP domain-containing protein compare
MMP_RS06630 -3.2 -0.6 UPF0058 family protein compare
MMP_RS06285 -3.1 -1.6 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS01265 -3.1 -2.3 hypothetical protein compare
MMP_RS02195 -3.1 -2.8 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS09055 -3.0 -0.8 CAP domain-containing protein compare
MMP_RS01800 -3.0 -3.1 TIGR00303 family protein compare
MMP_RS08210 -3.0 -1.4 phosphatidylglycerophosphatase A compare
MMP_RS01020 -3.0 -0.6 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06730 -3.0 -1.3 phosphopantothenate/pantothenate synthetase compare
MMP_RS01175 -2.9 -2.2 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS04780 -2.9 -1.8 ribonuclease P compare
MMP_RS04710 -2.9 -1.3 hypothetical protein compare
MMP_RS01270 -2.8 -15.4 prepilin peptidase compare
MMP_RS03580 -2.8 -2.4 signal recognition particle-docking protein FtsY compare
MMP_RS08820 -2.8 -3.7 hypothetical protein compare
MMP_RS07635 -2.8 -3.9 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS00245 -2.7 -18.0 type II secretion system F family protein compare
MMP_RS03035 -2.7 -2.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS08300 -2.7 -0.8 metal-sulfur cluster assembly factor compare
MMP_RS06350 -2.7 -4.6 HesA/MoeB/ThiF family protein compare
MMP_RS06295 -2.7 -5.2 methanogenesis marker 14 protein compare
MMP_RS03475 -2.6 -0.4 hypothetical protein compare
MMP_RS08785 -2.6 -0.6 RNA-protein complex protein Nop10 compare
MMP_RS01075 -2.6 -1.4 hypothetical protein compare
MMP_RS06400 -2.6 -0.9 4Fe-4S binding protein compare
MMP_RS03960 -2.6 -0.7 hypothetical protein compare
MMP_RS01310 -2.6 -14.2 hypothetical protein compare
MMP_RS08440 -2.6 -1.7 cell division protein SepF compare
MMP_RS04685 -2.6 -1.9 DUF126 domain-containing protein compare
MMP_RS00240 -2.6 -14.2 type II secretion system F family protein compare
MMP_RS00515 -2.6 -0.6 DUF655 domain-containing protein compare
MMP_RS01305 -2.5 -15.6 hypothetical protein compare
MMP_RS01925 -2.5 -4.7 DUF1616 domain-containing protein compare
MMP_RS01795 -2.5 -1.0 methanogenesis marker 6 protein compare
MMP_RS01280 -2.5 -12.3 DUF515 domain-containing protein compare
MMP_RS00250 -2.5 -14.8 Flp pilus assembly complex ATPase component TadA compare
MMP_RS01275 -2.5 -6.1 class III signal peptide-containing protein compare
MMP_RS05835 -2.5 -0.4 secondary thiamine-phosphate synthase enzyme YjbQ compare
MMP_RS01295 -2.5 -10.8 hypothetical protein compare
MMP_RS01900 -2.5 -8.0 hypothetical protein compare
MMP_RS05635 -2.4 -5.6 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS07200 -2.4 -4.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS01285 -2.4 -8.4 hypothetical protein compare
MMP_RS00810 -2.4 -4.2 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS00305 -2.4 -1.1 phosphoribosyl-ATP diphosphatase compare
MMP_RS01290 -2.4 -8.8 class III signal peptide-containing protein compare
MMP_RS03125 -2.4 -4.0 cell division ATPase MinD compare
MMP_RS07600 -2.4 -1.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS08855 -2.4 -7.2 hypothetical protein compare
MMP_RS06625 -2.4 -1.1 DNA primase compare
MMP_RS03600 -2.3 -1.4 triose-phosphate isomerase compare
MMP_RS08675 -2.3 -2.4 class III signal peptide-containing protein compare
MMP_RS00040 -2.3 -3.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS04900 -2.3 -14.2 hypothetical protein compare
MMP_RS06035 -2.3 -7.4 glycosyltransferase family 2 protein compare
MMP_RS00110 -2.3 -2.0 hypothetical protein compare
MMP_RS01315 -2.3 -15.2 DUF2341 domain-containing protein compare
MMP_RS03025 -2.3 -3.7 molybdenum cofactor guanylyltransferase compare
MMP_RS07330 -2.3 -14.8 membrane protein compare
MMP_RS00320 -2.3 -1.1 class I SAM-dependent methyltransferase compare
MMP_RS08155 -2.2 -4.6 hypothetical protein compare
MMP_RS04955 -2.2 -4.5 DNA topoisomerase I compare
MMP_RS06885 -2.2 -1.6 50S ribosome-binding GTPase compare
MMP_RS05845 -2.2 -1.0 tRNA-intron lyase compare
MMP_RS04090 -2.2 -1.8 hypothetical protein compare
MMP_RS08790 -2.2 -1.1 translation initiation factor IF-2 subunit alpha compare
MMP_RS07380 -2.2 -1.3 transcription elongation factor Spt5 compare
MMP_RS06725 -2.2 -5.7 hypothetical protein compare
MMP_RS02805 -2.2 -0.8 HEPN domain-containing protein compare
MMP_RS08195 -2.2 -5.5 hypothetical protein compare
MMP_RS07755 -2.1 -0.7 DUF555 domain-containing protein compare
MMP_RS06020 -2.1 -2.5 archaeoflavoprotein AfpA compare
MMP_RS07710 -2.1 -5.8 cell division protein FtsZ compare
MMP_RS03640 -2.1 -2.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01700 -2.1 -0.6 dihydroxy-acid dehydratase compare
MMP_RS06525 -2.1 -0.7 YciI family protein compare
MMP_RS02235 -2.1 -6.1 CBS domain-containing protein compare
MMP_RS01830 -2.1 -0.8 tRNA-Val compare
MMP_RS03110 -2.1 -3.3 glycosyltransferase family 2 protein compare
MMP_RS03080 -2.0 -2.0 universal stress protein compare
MMP_RS03700 -2.0 -4.8 sodium:proton antiporter compare
MMP_RS06340 -2.0 -4.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06925 -2.0 -1.6 ribonuclease VapC4 compare
MMP_RS01725 -2.0 -2.8 class I SAM-dependent methyltransferase family protein compare
MMP_RS06310 -2.0 -2.8 NAD(P)/FAD-dependent oxidoreductase compare
MMP_RS01720 -2.0 -1.4 replication factor C large subunit compare
MMP_RS03015 -2.0 -6.6 GTP 3' 8-cyclase MoaA compare
MMP_RS06600 -2.0 -0.7 class III signal peptide-containing protein compare
MMP_RS05580 -1.9 -10.1 glycosyltransferase compare
MMP_RS06105 -1.9 -5.4 hydrogenase maturation peptidase HycI compare
MMP_RS08860 -1.9 -4.1 MinD/ParA family protein compare
MMP_RS04775 -1.9 -2.0 adenosylhomocysteinase compare
MMP_RS00985 -1.9 -3.6 CDC48 family AAA ATPase compare
MMP_RS00735 -1.9 -2.1 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS01875 -1.9 -4.5 N-acetyltransferase compare
MMP_RS05345 -1.9 -4.1 hypothetical protein compare
MMP_RS07385 -1.9 -1.5 protein translocase SEC61 complex subunit gamma compare
MMP_RS09045 -1.9 -11.1 class III signal peptide-containing protein compare
MMP_RS02930 -1.9 -1.8 class I SAM-dependent methyltransferase compare
MMP_RS03095 -1.9 -4.9 diphthine synthase compare
MMP_RS00965 -1.9 -2.3 hypothetical protein compare
MMP_RS07750 -1.9 -3.0 DUF357 domain-containing protein compare
MMP_RS07605 -1.9 -2.1 diadenylate cyclase compare
MMP_RS01085 -1.9 -1.2 hypothetical protein compare
MMP_RS07355 -1.8 -0.6 transcription factor S compare
MMP_RS02355 -1.8 -1.7 30S ribosomal protein S27ae compare
MMP_RS00850 -1.8 -3.3 TIGR01177 family methyltransferase compare
MMP_RS00315 -1.8 -3.7 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01905 -1.8 -6.8 glycosyltransferase compare
MMP_RS05930 -1.8 -1.1 3-isopropylmalate dehydratase large subunit compare
MMP_RS03245 -1.8 -2.9 DNA repair and recombination protein RadB compare
MMP_RS06355 -1.8 -1.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS02480 -1.7 -1.3 hypothetical protein compare
MMP_RS06230 -1.7 -1.3 helix-turn-helix domain-containing protein compare
MMP_RS07875 -1.7 -3.2 hypothetical protein compare
MMP_RS01365 -1.7 -2.1 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS08660 -1.7 -5.1 DHH family phosphoesterase compare
MMP_RS00730 -1.7 -3.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS02345 -1.7 -2.1 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01665 -1.7 -2.7 DUF2111 domain-containing protein compare
MMP_RS01220 -1.7 -3.9 hypothetical protein compare
MMP_RS08645 -1.7 -4.3 UPF0179 family protein compare
MMP_RS06975 -1.7 -1.0 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS00115 -1.7 -8.0 radical SAM protein compare
MMP_RS05430 -1.6 -4.4 TIGR00288 family NYN domain-containing protein compare
MMP_RS03020 -1.6 -3.9 peptidylprolyl isomerase compare
MMP_RS06130 -1.6 -1.8 peptidylprolyl isomerase compare
MMP_RS01385 -1.6 -0.3 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS00915 -1.6 -3.5 DUF116 domain-containing protein compare
MMP_RS01885 -1.6 -3.5 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS04585 -1.6 -5.5 AIR synthase related protein compare
MMP_RS03145 -1.6 -4.0 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase compare
MMP_RS05355 -1.6 -0.4 hypothetical protein compare
MMP_RS04255 -1.5 -3.6 coenzyme F420 hydrogenase subunit beta compare
MMP_RS01195 -1.5 -0.7 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS06610 -1.5 -2.0 DUF2334 domain-containing protein compare
MMP_RS02135 -1.5 -2.3 DUF5612 domain-containing protein compare
MMP_RS06980 -1.5 -3.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS00895 -1.5 -2.1 hypothetical protein compare
MMP_RS08615 -1.5 -1.2 flagellar protein G compare
MMP_RS00140 -1.5 -3.9 DUF192 domain-containing protein compare
MMP_RS02835 -1.5 -2.0 CGGC domain-containing protein compare
MMP_RS02405 -1.5 -3.5 hypothetical protein compare
MMP_RS08940 -1.5 -0.8 MetS family NSS transporter small subunit compare
MMP_RS05815 -1.5 -1.1 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07525 -1.5 -4.8 4Fe-4S binding protein compare
MMP_RS01660 -1.4 -1.7 hypothetical protein compare
MMP_RS00520 -1.4 -0.6 RNA polymerase Rpb4 family protein compare
MMP_RS05295 -1.4 -2.8 minichromosome maintenance protein MCM compare
MMP_RS07545 -1.4 -0.6 HTH domain-containing protein compare
MMP_RS07075 -1.4 -1.7 phosphomannomutase/phosphoglucomutase compare
MMP_RS06865 -1.4 -1.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS05245 -1.4 -5.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08745 -1.4 -2.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00725 -1.4 -3.6 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS08435 -1.4 -1.1 Era-like GTP-binding protein compare
MMP_RS04720 -1.4 -1.0 DedA family protein compare
MMP_RS05445 -1.4 -5.6 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS01880 -1.3 -1.9 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06290 -1.3 -2.4 DNA repair and recombination protein RadA compare
MMP_RS01895 -1.3 -5.9 flippase compare
MMP_RS01045 -1.3 -3.8 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS01745 -1.3 -2.9 AMP phosphorylase compare
MMP_RS05965 -1.3 -1.4 carboxymuconolactone decarboxylase family protein compare
MMP_RS04480 -1.3 -5.3 lysine 2 3-aminomutase compare
MMP_RS06395 -1.3 -1.6 ThiF family adenylyltransferase compare
MMP_RS07350 -1.3 -1.0 preprotein translocase subunit Sec61beta compare
MMP_RS07695 -1.3 -3.3 DUF3236 domain-containing protein compare
MMP_RS08200 -1.3 -7.2 archaeosine synthase subunit alpha compare
MMP_RS07700 -1.3 -4.2 DUF1188 domain-containing protein compare
MMP_RS03120 -1.3 -1.5 hypothetical protein compare
MMP_RS02800 -1.3 -3.0 nucleotidyltransferase domain-containing protein compare
MMP_RS07575 -1.3 -1.6 RNA ligase partner protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Metronidazole across organisms