Experiment set11S206 for Methanococcus maripaludis S2

Compare to:

McCas_H2_complete Chlorpromazine hydrochloride 0.0333333333333333 mM

200 most important genes:

  gene name fitness t score description  
MMP_RS05550 -6.2 -0.6 cation:proton antiporter compare
MMP_RS03315 -5.9 -1.0 ferrous iron transport protein A compare
MMP_RS04710 -5.7 -1.8 hypothetical protein compare
MMP_RS02900 -5.2 -0.5 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS03445 -5.2 -0.7 methanogenesis marker 17 protein compare
MMP_RS05920 -5.1 -0.5 50S ribosomal protein L37e compare
MMP_RS07545 -5.0 -0.7 HTH domain-containing protein compare
MMP_RS01610 -4.8 -2.4 hypothetical protein compare
MMP_RS01545 -4.7 -0.8 CBS domain-containing protein compare
MMP_RS00695 -4.6 -0.6 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00515 -3.9 -0.8 DUF655 domain-containing protein compare
MMP_RS07390 -3.8 -2.2 cell division protein FtsZ compare
MMP_RS01225 -3.7 -3.8 DUF5379 domain-containing protein compare
MMP_RS09020 -3.6 -1.3 hypothetical protein compare
MMP_RS01700 -3.5 -0.9 dihydroxy-acid dehydratase compare
MMP_RS03960 -3.3 -0.9 hypothetical protein compare
MMP_RS06350 -3.2 -5.5 HesA/MoeB/ThiF family protein compare
MMP_RS04720 -3.2 -2.2 DedA family protein compare
MMP_RS01175 -3.1 -3.0 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS04890 -3.1 -0.6 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06600 -3.0 -0.9 class III signal peptide-containing protein compare
MMP_RS08820 -3.0 -4.7 hypothetical protein compare
MMP_RS05845 -3.0 -1.5 tRNA-intron lyase compare
MMP_RS06230 -2.9 -2.4 helix-turn-helix domain-containing protein compare
MMP_RS07355 -2.9 -0.8 transcription factor S compare
MMP_RS06925 -2.9 -2.4 ribonuclease VapC4 compare
MMP_RS07735 -2.9 -0.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS06110 -2.8 -3.0 ATP-dependent protease LonB compare
MMP_RS07845 -2.8 -2.9 LL-diaminopimelate aminotransferase compare
MMP_RS06295 -2.8 -7.0 methanogenesis marker 14 protein compare
MMP_RS08715 -2.7 -1.2 formylmethanofuran dehydrogenase subunit B compare
MMP_RS08860 -2.7 -4.3 MinD/ParA family protein compare
MMP_RS07635 -2.6 -5.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06315 -2.6 -0.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS02800 -2.6 -4.7 nucleotidyltransferase domain-containing protein compare
MMP_RS00250 -2.5 -13.7 Flp pilus assembly complex ATPase component TadA compare
MMP_RS08650 -2.5 -2.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01275 -2.5 -5.7 class III signal peptide-containing protein compare
MMP_RS01755 -2.5 -0.9 DUF2097 domain-containing protein compare
MMP_RS09055 -2.5 -1.0 CAP domain-containing protein compare
MMP_RS01265 -2.5 -2.9 hypothetical protein compare
MMP_RS00520 -2.4 -1.4 RNA polymerase Rpb4 family protein compare
MMP_RS01270 -2.4 -13.1 prepilin peptidase compare
MMP_RS01800 -2.4 -3.1 TIGR00303 family protein compare
MMP_RS03035 -2.4 -3.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS01310 -2.4 -15.9 hypothetical protein compare
MMP_RS03640 -2.4 -2.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS01285 -2.4 -8.9 hypothetical protein compare
MMP_RS02145 -2.3 -6.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS00305 -2.3 -1.4 phosphoribosyl-ATP diphosphatase compare
MMP_RS00240 -2.3 -13.5 type II secretion system F family protein compare
MMP_RS00040 -2.3 -4.9 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS07005 -2.2 -0.5 4Fe-4S binding protein compare
MMP_RS01290 -2.2 -10.2 class III signal peptide-containing protein compare
MMP_RS00810 -2.2 -5.4 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS01280 -2.2 -12.3 DUF515 domain-containing protein compare
MMP_RS00245 -2.2 -15.6 type II secretion system F family protein compare
MMP_RS01305 -2.2 -16.1 hypothetical protein compare
MMP_RS01295 -2.2 -11.3 hypothetical protein compare
MMP_RS07750 -2.2 -3.1 DUF357 domain-containing protein compare
MMP_RS06725 -2.2 -6.4 hypothetical protein compare
MMP_RS08855 -2.1 -8.3 hypothetical protein compare
MMP_RS06730 -2.1 -1.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS07605 -2.1 -2.8 diadenylate cyclase compare
MMP_RS08435 -2.1 -1.5 Era-like GTP-binding protein compare
MMP_RS01315 -2.1 -16.1 DUF2341 domain-containing protein compare
MMP_RS08675 -2.1 -2.6 class III signal peptide-containing protein compare
MMP_RS00300 -2.1 -0.5 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS03385 -2.1 -0.8 cation diffusion facilitator family transporter compare
MMP_RS08440 -2.1 -2.2 cell division protein SepF compare
MMP_RS00320 -2.0 -1.3 class I SAM-dependent methyltransferase compare
MMP_RS01795 -2.0 -1.1 methanogenesis marker 6 protein compare
MMP_RS01195 -2.0 -1.1 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS03580 -2.0 -2.2 signal recognition particle-docking protein FtsY compare
MMP_RS01725 -2.0 -3.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS07555 -2.0 -0.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS01665 -2.0 -3.4 DUF2111 domain-containing protein compare
MMP_RS03125 -2.0 -5.3 cell division ATPase MinD compare
MMP_RS08300 -2.0 -0.9 metal-sulfur cluster assembly factor compare
MMP_RS00735 -1.9 -2.9 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS04775 -1.9 -2.5 adenosylhomocysteinase compare
MMP_RS01020 -1.9 -0.7 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00315 -1.9 -5.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01500 -1.9 -1.4 CBS domain-containing protein compare
MMP_RS03700 -1.9 -4.5 sodium:proton antiporter compare
MMP_RS07330 -1.9 -12.0 membrane protein compare
MMP_RS07575 -1.9 -2.6 RNA ligase partner protein compare
MMP_RS00725 -1.9 -3.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS06355 -1.9 -1.7 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS00675 -1.8 -0.6 nitroreductase family protein compare
MMP_RS09045 -1.8 -11.1 class III signal peptide-containing protein compare
MMP_RS00985 -1.8 -4.5 CDC48 family AAA ATPase compare
MMP_RS06625 -1.8 -1.1 DNA primase compare
MMP_RS03435 -1.8 -0.9 ketol-acid reductoisomerase compare
MMP_RS05635 -1.8 -6.1 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS05515 -1.8 -5.8 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03400 -1.8 -1.5 archease compare
MMP_RS01955 -1.8 -1.4 hypothetical protein compare
MMP_RS08195 -1.8 -6.8 hypothetical protein compare
MMP_RS08745 -1.8 -3.7 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS01385 -1.8 -0.4 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS03015 -1.7 -7.0 GTP 3' 8-cyclase MoaA compare
MMP_RS07695 -1.7 -4.3 DUF3236 domain-containing protein compare
MMP_RS04900 -1.7 -12.4 hypothetical protein compare
MMP_RS06340 -1.7 -5.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00685 -1.7 -2.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01100 -1.7 -1.1 ABC transporter ATP-binding protein compare
MMP_RS06120 -1.7 -1.3 UPF0147 family protein compare
MMP_RS08790 -1.7 -1.3 translation initiation factor IF-2 subunit alpha compare
MMP_RS04850 -1.7 -11.0 UPF0254 family protein compare
MMP_RS07420 -1.7 -4.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08720 -1.7 -0.9 4Fe-4S binding protein compare
MMP_RS05555 -1.7 -1.2 DUF4040 domain-containing protein compare
MMP_RS00115 -1.7 -7.3 radical SAM protein compare
MMP_RS07900 -1.7 -2.1 YeeE/YedE family protein compare
MMP_RS07350 -1.7 -1.4 preprotein translocase subunit Sec61beta compare
MMP_RS01005 -1.7 -0.9 riboflavin synthase compare
MMP_RS04685 -1.6 -1.4 DUF126 domain-containing protein compare
MMP_RS06035 -1.6 -8.0 glycosyltransferase family 2 protein compare
MMP_RS05580 -1.6 -8.3 glycosyltransferase compare
MMP_RS02235 -1.6 -6.6 CBS domain-containing protein compare
MMP_RS01365 -1.6 -2.5 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS03080 -1.6 -2.2 universal stress protein compare
MMP_RS03600 -1.6 -1.3 triose-phosphate isomerase compare
MMP_RS02010 -1.6 -4.7 PHP domain-containing protein compare
MMP_RS03025 -1.6 -3.0 molybdenum cofactor guanylyltransferase compare
MMP_RS01900 -1.6 -7.0 hypothetical protein compare
MMP_RS07380 -1.6 -1.1 transcription elongation factor Spt5 compare
MMP_RS01085 -1.5 -1.4 hypothetical protein compare
MMP_RS06980 -1.5 -5.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS08210 -1.5 -1.5 phosphatidylglycerophosphatase A compare
MMP_RS05540 -1.5 -2.8 hypothetical protein compare
MMP_RS08940 -1.5 -1.0 MetS family NSS transporter small subunit compare
MMP_RS06885 -1.5 -1.4 50S ribosome-binding GTPase compare
MMP_RS06285 -1.5 -1.7 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00110 -1.5 -1.4 hypothetical protein compare
MMP_RS05355 -1.5 -0.6 hypothetical protein compare
MMP_RS06105 -1.5 -5.8 hydrogenase maturation peptidase HycI compare
MMP_RS00730 -1.5 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS05815 -1.5 -1.2 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS05345 -1.5 -3.9 hypothetical protein compare
MMP_RS04615 -1.4 -1.7 PDGLE domain-containing protein compare
MMP_RS02195 -1.4 -1.9 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS03095 -1.4 -4.1 diphthine synthase compare
MMP_RS02280 -1.4 -0.4 DUF211 domain-containing protein compare
MMP_RS01720 -1.4 -1.3 replication factor C large subunit compare
MMP_RS07955 -1.4 -4.1 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06395 -1.4 -2.0 ThiF family adenylyltransferase compare
MMP_RS03485 -1.4 -3.4 TIGR00267 family protein compare
MMP_RS04125 -1.4 -2.1 TetR/AcrR family transcriptional regulator compare
MMP_RS01905 -1.3 -4.8 glycosyltransferase compare
MMP_RS08370 -1.3 -0.4 cation:proton antiporter subunit C compare
MMP_RS07525 -1.3 -4.3 4Fe-4S binding protein compare
MMP_RS00915 -1.3 -4.1 DUF116 domain-containing protein compare
MMP_RS05640 -1.3 -3.7 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS07710 -1.3 -4.0 cell division protein FtsZ compare
MMP_RS07445 -1.3 -3.5 helix-turn-helix domain-containing protein compare
MMP_RS05430 -1.3 -3.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS03110 -1.3 -2.6 glycosyltransferase family 2 protein compare
MMP_RS06270 -1.3 -2.8 TIGR00300 family protein compare
MMP_RS02345 -1.2 -1.7 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS00570 -1.2 -1.8 protein-L-isoaspartate O-methyltransferase compare
MMP_RS04955 -1.2 -3.3 DNA topoisomerase I compare
MMP_RS07875 -1.2 -2.1 hypothetical protein compare
MMP_RS03390 -1.2 -4.8 malate dehydrogenase compare
MMP_RS07700 -1.2 -4.3 DUF1188 domain-containing protein compare
MMP_RS07600 -1.2 -1.5 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS02240 -1.2 -1.5 methanogenesis marker 7 protein compare
MMP_RS08645 -1.2 -3.2 UPF0179 family protein compare
MMP_RS04585 -1.2 -4.7 AIR synthase related protein compare
MMP_RS06400 -1.2 -0.6 4Fe-4S binding protein compare
MMP_RS01220 -1.1 -4.5 hypothetical protein compare
MMP_RS06715 -1.1 -6.4 cache domain-containing protein compare
MMP_RS06630 -1.1 -0.4 UPF0058 family protein compare
MMP_RS02540 -1.1 -2.0 DUF2283 domain-containing protein compare
MMP_RS03520 -1.1 -1.1 YwbE family protein compare
MMP_RS05245 -1.1 -3.6 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS07200 -1.1 -3.0 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS02470 -1.1 -0.7 helix-turn-helix transcriptional regulator compare
MMP_RS00750 -1.1 -1.2 fumarate hydratase compare
MMP_RS04090 -1.1 -1.6 hypothetical protein compare
MMP_RS01830 -1.1 -0.8 tRNA-Val compare
MMP_RS07730 -1.1 -0.9 pyruvate synthase subunit beta compare
MMP_RS03020 -1.1 -2.7 peptidylprolyl isomerase compare
MMP_RS06720 -1.1 -5.6 response regulator transcription factor compare
MMP_RS08330 -1.1 -3.3 NADH-quinone oxidoreductase subunit H compare
MMP_RS05425 -1.1 -2.4 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS05925 -1.1 -1.7 small nuclear ribonucleoprotein compare
MMP_RS08155 -1.0 -4.0 hypothetical protein compare
MMP_RS06855 -1.0 -3.8 hypothetical protein compare
MMP_RS04255 -1.0 -3.3 coenzyme F420 hydrogenase subunit beta compare
MMP_RS00895 -1.0 -2.3 hypothetical protein compare
MMP_RS07090 -1.0 -3.2 tRNA (adenine-N1)-methyltransferase compare
MMP_RS02340 -1.0 -1.2 DNA-directed RNA polymerase subunit E'' compare
MMP_RS06895 -1.0 -0.9 selenocysteine-specific translation elongation factor compare
MMP_RS06130 -1.0 -1.4 peptidylprolyl isomerase compare
MMP_RS06445 -1.0 -2.2 DUF89 domain-containing protein compare
MMP_RS07755 -1.0 -0.6 DUF555 domain-containing protein compare
MMP_RS01575 -1.0 -3.0 aldolase compare
MMP_RS07425 -1.0 -3.1 GTP-binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in stress experiments

For stress Chlorpromazine hydrochloride across organisms