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Experiment set11IT086 for
Klebsiella michiganensis M5al
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RCH2_defined_Glucose_noNitrogen in EcoFAB_3.5mL
200 most important genes:
gene
name
fitness
t score
description
BWI76
_RS26875
-4.7
-3.0
dipeptide ABC transporter permease DppC
compare
BWI76
_RS05835
-4.7
-2.6
gamma-glutamyl-phosphate reductase
compare
BWI76
_RS09645
-4.6
-1.3
thioredoxin-disulfide reductase
compare
BWI76
_RS26085
-4.4
-2.2
3-dehydroquinate synthase
compare
BWI76
_RS13560
-4.2
-1.2
amino acid ABC transporter substrate-binding subunit
compare
BWI76
_RS04305
-4.1
-1.2
molecular chaperone DnaJ
compare
BWI76
_RS20750
-4.0
-1.1
carboxysome structural protein EutK
compare
BWI76
_RS07730
-4.0
-1.1
iron-enterobactin transporter membrane protein
compare
BWI76
_RS23895
-3.8
-1.9
Xaa-Pro aminopeptidase
compare
BWI76
_RS26620
-3.7
-1.1
Fe-S biogenesis protein NfuA
compare
BWI76
_RS15660
-3.5
-1.0
hypothetical protein
compare
BWI76
_RS05200
-3.3
-2.3
bifunctional uridylyltransferase/uridylyl-removing protein
compare
BWI76
_RS17720
-3.3
-1.3
muramoyltetrapeptide carboxypeptidase
compare
BWI76
_RS01200
-3.3
-2.1
diaminopimelate epimerase
compare
BWI76
_RS09660
-3.2
-2.0
DNA translocase FtsK
compare
BWI76
_RS08385
-3.2
-3.2
citrate (Si)-synthase
compare
BWI76
_RS16235
-3.1
-3.6
membrane protein
compare
BWI76
_RS11235
-3.0
-1.2
hypothetical protein
compare
BWI76
_RS15290
-3.0
-1.4
transcriptional regulator
compare
BWI76
_RS05015
-2.9
-2.1
transcriptional regulator
compare
BWI76
_RS11610
-2.9
-2.5
glutamate dehydrogenase
compare
BWI76
_RS09970
-2.8
-3.8
porin OmpA
compare
BWI76
_RS00805
-2.7
-4.6
5,10-methylenetetrahydrofolate reductase
compare
BWI76
_RS21810
-2.7
-1.8
universal stress protein
compare
BWI76
_RS25160
-2.7
-1.5
transcription elongation factor GreA
compare
BWI76
_RS12090
-2.7
-3.0
HNH endonuclease
compare
BWI76
_RS23265
-2.6
-2.2
hypothetical protein
compare
BWI76
_RS08330
-2.5
-1.4
hypothetical protein
compare
BWI76
_RS25000
-2.5
-1.0
malonate decarboxylase acyl carrier protein
compare
BWI76
_RS18930
-2.4
-3.9
histidinol-phosphate transaminase
compare
BWI76
_RS25480
-2.4
-3.0
ribonuclease E/G
compare
BWI76
_RS14755
-2.4
-1.8
SIS domain-containing protein
compare
BWI76
_RS26075
-2.4
-3.0
DNA adenine methylase
compare
BWI76
_RS10835
-2.4
-1.6
hypothetical protein
compare
BWI76
_RS14170
-2.3
-2.9
hypothetical protein
compare
BWI76
_RS07070
-2.3
-3.0
5-(carboxyamino)imidazole ribonucleotide mutase
compare
BWI76
_RS06530
-2.3
-5.2
ATP-dependent Clp protease ATP-binding subunit ClpX
compare
BWI76
_RS04715
-2.3
-1.5
division/cell wall cluster transcriptional repressor MraZ
compare
BWI76
_RS20380
-2.3
-1.1
tRNA pseudouridine(38-40) synthase TruA
compare
BWI76
_RS08535
-2.3
-1.9
translocation protein TolB
compare
BWI76
_RS08525
-2.3
-3.5
colicin transporter
compare
BWI76
_RS13070
-2.3
-2.8
hypothetical protein
compare
BWI76
_RS17310
-2.2
-3.1
AsnC family transcriptional regulator
compare
BWI76
_RS14415
-2.2
-2.7
transcriptional regulator, TetR family protein
compare
BWI76
_RS20360
-2.2
-0.9
cell division protein DedD
compare
BWI76
_RS17570
-2.2
-2.3
iron-sulfur-binding protein
compare
BWI76
_RS04515
-2.2
-1.4
Co2+/Mg2+ efflux protein ApaG
compare
BWI76
_RS26405
-2.2
-0.9
16S rRNA (guanine(966)-N(2))-methyltransferase
compare
BWI76
_RS23050
-2.2
-2.1
cobalt-precorrin-3B C(17)-methyltransferase
compare
BWI76
_RS21505
-2.2
-1.2
hypothetical protein
compare
BWI76
_RS06595
-2.2
-1.9
hypothetical protein
compare
BWI76
_RS18360
-2.2
-1.9
aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein
compare
BWI76
_RS03010
-2.1
-6.3
ornithine carbamoyltransferase
compare
BWI76
_RS23530
-2.1
-2.8
MarR family transcriptional regulator
compare
BWI76
_RS18575
-2.1
-1.4
transcriptional regulator
compare
BWI76
_RS25070
-2.1
-1.1
hypothetical protein
compare
BWI76
_RS18165
-2.0
-1.1
NUDIX pyrophosphatase
compare
BWI76
_RS15215
-2.0
-1.0
N-acetyltransferase
compare
BWI76
_RS23230
-2.0
-3.2
exodeoxyribonuclease V subunit beta
compare
BWI76
_RS27440
-2.0
-3.1
DNA helicase RecG
compare
BWI76
_RS22805
-2.0
-6.1
GTP diphosphokinase
compare
BWI76
_RS05260
-2.0
-1.5
chaperone
compare
BWI76
_RS04470
-2.0
-6.2
carbamoyl phosphate synthase large subunit
compare
BWI76
_RS01655
-2.0
-4.2
homoserine O-succinyltransferase
compare
BWI76
_RS26570
-2.0
-2.3
anion permease
compare
BWI76
_RS27820
-1.9
-1.5
ilvB operon leader peptide IvbL
compare
BWI76
_RS07380
-1.9
-1.8
hypothetical protein
compare
BWI76
_RS09130
-1.9
-2.6
biofilm formation regulatory protein BssR
compare
BWI76
_RS15825
-1.8
-2.0
hypothetical protein
compare
BWI76
_RS25320
-1.8
-5.1
glutamate synthase
compare
BWI76
_RS16035
-1.8
-2.2
biotin-independent malonate decarboxylase subunit beta
compare
BWI76
_RS27430
-1.8
-0.7
(p)ppGpp synthetase
compare
BWI76
_RS16000
-1.8
-1.0
multidrug transporter subunit MdtI
compare
BWI76
_RS17200
-1.8
-1.2
hypothetical protein
compare
BWI76
_RS05840
-1.8
-2.5
glutamate 5-kinase
compare
BWI76
_RS08605
-1.7
-2.3
phosphoglyceromutase
compare
BWI76
_RS04250
-1.7
-3.6
homoserine kinase
compare
BWI76
_RS05235
-1.7
-0.9
hypothetical protein
compare
BWI76
_RS11965
-1.7
-2.0
orotidine-5'-phosphate decarboxylase
compare
BWI76
_RS11855
-1.7
-5.0
bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase
compare
BWI76
_RS01185
-1.7
-1.6
adenylate cyclase
compare
BWI76
_RS01110
-1.7
-2.2
TDP-fucosamine acetyltransferase
compare
BWI76
_RS06485
-1.6
-1.7
cytochrome o ubiquinol oxidase subunit III
compare
BWI76
_RS11850
-1.6
-6.7
bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase
compare
BWI76
_RS21350
-1.6
-2.8
anti-RNA polymerase sigma factor SigE
compare
BWI76
_RS11860
-1.6
-4.2
anthranilate synthase component I
compare
BWI76
_RS01385
-1.6
-2.4
potassium transporter
compare
BWI76
_RS25280
-1.6
-1.4
RNase adaptor protein RapZ
compare
BWI76
_RS23920
-1.6
-4.0
D-3-phosphoglycerate dehydrogenase
compare
BWI76
_RS19775
-1.6
-1.7
phage resistance protein
compare
BWI76
_RS26270
-1.6
-2.7
N-acetyltransferase
compare
BWI76
_RS12040
-1.6
-1.0
hypothetical protein
compare
BWI76
_RS00140
-1.6
-0.8
phosphate transport system regulator PhoU
compare
BWI76
_RS01610
-1.6
-4.5
phosphoribosylamine--glycine ligase
compare
BWI76
_RS21580
-1.6
-1.3
SsrA-binding protein
compare
BWI76
_RS11845
-1.6
-2.3
tryptophan synthase subunit beta
compare
BWI76
_RS04160
-1.6
-3.7
phosphoserine phosphatase
compare
BWI76
_RS20880
-1.6
-1.3
esterase
compare
BWI76
_RS00850
-1.6
-5.6
acetylglutamate kinase
compare
BWI76
_RS06605
-1.6
-3.9
ammonium transporter
compare
BWI76
_RS09755
-1.6
-3.9
phosphoserine transaminase
compare
BWI76
_RS16425
-1.5
-1.8
hypothetical protein
compare
BWI76
_RS26395
-1.5
-3.3
cell division protein FtsE
compare
BWI76
_RS16260
-1.5
-1.2
two-component sensor histidine kinase
compare
BWI76
_RS18780
-1.5
-1.5
D-alanyl-D-alanine carboxypeptidase
compare
BWI76
_RS15350
-1.5
-0.9
hypothetical protein
compare
BWI76
_RS18925
-1.5
-2.8
histidinol dehydrogenase
compare
BWI76
_RS25315
-1.5
-6.4
glutamate synthase large subunit
compare
BWI76
_RS18935
-1.5
-2.8
bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase
compare
BWI76
_RS15115
-1.5
-4.7
MFS transporter
compare
BWI76
_RS02530
-1.5
-1.3
tRNA dimethylallyltransferase
compare
BWI76
_RS24285
-1.5
-4.1
cystathionine beta-lyase
compare
BWI76
_RS23220
-1.5
-3.8
amino-acid N-acetyltransferase
compare
BWI76
_RS17530
-1.5
-2.0
hypothetical protein
compare
BWI76
_RS21465
-1.5
-3.0
bifunctional chorismate mutase/prephenate dehydratase
compare
BWI76
_RS08750
-1.5
-1.0
kinase inhibitor
compare
BWI76
_RS26455
-1.5
-1.6
4-amino-4-deoxy-L-arabinose-phospho-UDP flippase
compare
BWI76
_RS00855
-1.5
-4.1
argininosuccinate lyase
compare
BWI76
_RS14625
-1.4
-1.1
protein TolA
compare
BWI76
_RS09450
-1.4
-1.4
30S ribosomal protein S6--L-glutamate ligase
compare
BWI76
_RS14410
-1.4
-2.4
hypothetical protein
compare
BWI76
_RS01615
-1.4
-4.8
bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase
compare
BWI76
_RS18955
-1.4
-3.1
bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase
compare
BWI76
_RS26045
-1.4
-1.6
nitrite reductase small subunit
compare
BWI76
_RS18550
-1.4
-0.9
tRNA-Asn
compare
BWI76
_RS27940
-1.4
-1.8
2-dehydro-3-deoxy-6-phosphogalactonate aldolase
compare
BWI76
_RS09910
-1.4
-8.7
dihydroorotate dehydrogenase (quinone)
compare
BWI76
_RS21345
-1.4
-1.5
sigma-E factor regulatory protein RseB
compare
BWI76
_RS15845
-1.4
-0.8
hypothetical protein
compare
BWI76
_RS20350
-1.4
-3.5
amidophosphoribosyltransferase
compare
BWI76
_RS04245
-1.4
-5.0
bifunctional aspartate kinase/homoserine dehydrogenase I
compare
BWI76
_RS23880
-1.4
-4.3
Aminomethyltransferase (EC 2.1.2.10)
(from data)
compare
BWI76
_RS10280
-1.4
-3.5
polar amino acid ABC transporter permease
compare
BWI76
_RS26520
-1.4
-2.5
nickel import ATP-binding protein NikE
compare
BWI76
_RS03655
-1.4
-3.7
hypothetical protein
compare
BWI76
_RS01210
-1.4
-1.1
tyrosine recombinase XerC
compare
BWI76
_RS18950
-1.4
-2.5
imidazole glycerol phosphate synthase cyclase subunit
compare
BWI76
_RS08180
-1.4
-5.5
asparagine synthase B
compare
BWI76
_RS15975
-1.4
-0.8
hypothetical protein
compare
BWI76
_RS23250
-1.4
-1.4
hypothetical protein
compare
BWI76
_RS00385
-1.3
-4.2
nitrogen assimilation regulatory protein
compare
BWI76
_RS02580
-1.3
-0.9
23S rRNA (guanosine(2251)-2'-O)-methyltransferase
compare
BWI76
_RS07255
-1.3
-2.0
hypothetical protein
compare
BWI76
_RS10945
-1.3
-1.7
SecY/SecA suppressor protein
compare
BWI76
_RS07065
-1.3
-3.4
5-(carboxyamino)imidazole ribonucleotide synthase
compare
BWI76
_RS04255
-1.3
-5.1
threonine synthase
compare
BWI76
_RS02995
-1.3
-3.6
aspartate carbamoyltransferase
compare
BWI76
_RS27460
-1.3
-2.0
hypothetical protein
compare
BWI76
_RS17765
-1.3
-1.9
hypothetical protein
compare
BWI76
_RS06475
-1.3
-1.0
protoheme IX farnesyltransferase
compare
BWI76
_RS03920
-1.3
-1.8
N-acetyltransferase
compare
BWI76
_RS23365
-1.3
-4.2
LysR family transcriptional regulator
compare
BWI76
_RS00835
-1.3
-5.9
phosphoenolpyruvate carboxylase
compare
BWI76
_RS04510
-1.3
-1.0
bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
compare
BWI76
_RS21570
-1.3
-1.5
RnfH family protein
compare
BWI76
_RS19845
-1.3
-3.0
phosphatase
compare
BWI76
_RS22690
-1.3
-1.8
adenylyl-sulfate kinase
compare
BWI76
_RS17920
-1.3
-1.7
23S rRNA (guanine(745)-N(1))-methyltransferase
compare
BWI76
_RS20995
-1.3
-2.6
RNA degradosome polyphosphate kinase
compare
BWI76
_RS20895
-1.3
-2.4
phosphoribosylaminoimidazolesuccinocarboxamide synthase
compare
BWI76
_RS15295
-1.2
-3.3
MDR efflux pump AcrAB transcriptional activator MarA
compare
BWI76
_RS09480
-1.2
-2.6
hypothetical protein
compare
BWI76
_RS08615
-1.2
-3.0
galactokinase
compare
BWI76
_RS18125
-1.2
-1.5
murein DD-endopeptidase MepM
compare
BWI76
_RS25425
-1.2
-0.9
arginine repressor
compare
BWI76
_RS20390
-1.2
-0.9
erythronate-4-phosphate dehydrogenase
compare
BWI76
_RS00845
-1.2
-4.2
N-acetyl-gamma-glutamyl-phosphate reductase
compare
BWI76
_RS19325
-1.2
-0.9
mandelate racemase
compare
BWI76
_RS16490
-1.2
-1.4
glutaredoxin
compare
BWI76
_RS22765
-1.2
-4.5
sulfite reductase subunit alpha
compare
BWI76
_RS00980
-1.2
-5.6
PLP-dependent threonine dehydratase
compare
BWI76
_RS19035
-1.2
-4.0
dTDP-rhamnosyl transferase
compare
BWI76
_RS27305
-1.2
-2.9
glycosyl transferase
compare
BWI76
_RS25285
-1.2
-0.7
HPr family phosphocarrier protein
compare
BWI76
_RS20435
-1.2
-0.8
chorismate synthase
compare
BWI76
_RS17195
-1.2
-1.5
hypothetical protein
compare
BWI76
_RS06800
-1.2
-0.7
DUF2496 domain-containing protein
compare
BWI76
_RS15940
-1.2
-0.9
DMSO reductase maturation protein DsmD
compare
BWI76
_RS11335
-1.2
-1.1
tautomerase
compare
BWI76
_RS19985
-1.2
-2.1
MFS transporter
compare
BWI76
_RS21265
-1.2
-5.8
phosphoribosylformylglycinamidine synthase
compare
BWI76
_RS22760
-1.1
-3.4
sulfite reductase subunit beta
compare
BWI76
_RS14305
-1.1
-2.8
metallophosphoesterase
compare
BWI76
_RS01205
-1.1
-1.1
DUF484 family protein
compare
BWI76
_RS24600
-1.1
-2.9
dihydroxyacetone kinase
compare
BWI76
_RS00390
-1.1
-2.1
two-component system sensor histidine kinase NtrB
compare
BWI76
_RS00965
-1.1
-0.7
acetolactate synthase 2 small subunit
compare
BWI76
_RS10655
-1.1
-1.4
[formate-C-acetyltransferase]-activating enzyme
compare
BWI76
_RS09140
-1.1
-1.9
glutathione S-transferase
compare
BWI76
_RS23885
-1.1
-0.8
2-octaprenylphenol hydroxylase
compare
BWI76
_RS21140
-1.1
-1.2
molecular chaperone HscA
compare
BWI76
_RS14240
-1.1
-2.3
thiol reductase thioredoxin
compare
BWI76
_RS09505
-1.1
-1.8
arginine transporter permease subunit ArtM
compare
BWI76
_RS21565
-1.1
-0.7
outer membrane protein assembly factor BamE
compare
BWI76
_RS11490
-1.1
-2.1
MltA-interacting protein MipA
compare
BWI76
_RS27385
-1.1
-2.9
orotate phosphoribosyltransferase
compare
BWI76
_RS09725
-1.1
-1.6
MurR/RpiR family transcriptional regulator
compare
BWI76
_RS22755
-1.1
-3.2
phosphoadenosine phosphosulfate reductase
compare
BWI76
_RS23240
-1.1
-1.9
exonuclease V subunit gamma
compare
BWI76
_RS27550
-1.1
-1.9
hypothetical protein
compare
Specific Phenotypes
None in this experiment
For Klebsiella michiganensis M5al in ecofab experiments