Experiment set11IT085 for Klebsiella michiganensis M5al

Compare to:

RCH2_defined_Glucose_noNitrogen in EcoFAB_3.5mL

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS22430 +3.1 1.6 manganese/iron transporter ATP-binding protein compare
BWI76_RS09450 +3.0 1.8 30S ribosomal protein S6--L-glutamate ligase compare
BWI76_RS26300 +2.7 1.6 glycerol-3-phosphate transporter permease compare
BWI76_RS19465 +2.6 4.9 hypothetical protein compare
BWI76_RS18070 +2.5 2.1 DNA polymerase III subunit epsilon compare
BWI76_RS18725 +2.5 1.8 hypothetical protein compare
BWI76_RS21165 +2.3 3.8 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS23025 +2.2 6.4 cobalt ABC transporter substrate-binding protein CbiN compare
BWI76_RS17750 +2.1 3.1 Na+/H+ antiporter NhaB compare
BWI76_RS14980 +2.1 1.8 hypothetical protein compare
BWI76_RS11980 +2.0 1.8 DeoR family transcriptional regulator compare
BWI76_RS07255 +2.0 2.0 hypothetical protein compare
BWI76_RS13135 +1.9 1.4 3-oxoadipyl-CoA thiolase compare
BWI76_RS05520 +1.8 2.0 hypothetical protein compare
BWI76_RS21685 +1.8 2.4 hypothetical protein compare
BWI76_RS03185 +1.6 4.1 CI repressor compare
BWI76_RS06250 +1.6 1.3 alpha-glycosidase compare
BWI76_RS17200 +1.6 2.2 hypothetical protein compare
BWI76_RS05430 +1.6 2.9 UbiE/COQ5 family methyltransferase compare
BWI76_RS10855 +1.6 1.5 RND family efflux transporter MFP subunit compare
BWI76_RS06735 +1.6 2.5 50S ribosomal protein L31 compare
BWI76_RS00885 +1.5 2.2 tRNA (uridine(54)-C5)-methyltransferase TrmA compare
BWI76_RS11500 +1.5 2.2 D-hexose-6-phosphate mutarotase compare
BWI76_RS00725 +1.5 0.9 periplasmic repressor CpxP compare
BWI76_RS16000 +1.5 1.7 multidrug transporter subunit MdtI compare
BWI76_RS16850 +1.4 1.3 ABC transporter periplasmic substrate-binding protein compare
BWI76_RS13240 +1.4 1.5 hypothetical protein compare
BWI76_RS16580 +1.4 1.6 ubiquinol oxidase subunit II compare
BWI76_RS25870 +1.4 1.7 elongation factor Tu compare
BWI76_RS15920 +1.4 1.9 hypothetical protein compare
BWI76_RS24600 +1.4 2.0 dihydroxyacetone kinase compare
BWI76_RS23245 +1.4 2.1 hypothetical protein compare
BWI76_RS16300 +1.4 1.6 bifunctional beta-cystathionase/maltose regulon regulatory protein compare
BWI76_RS22510 +1.4 4.4 hypothetical protein compare
BWI76_RS15565 +1.4 1.4 hypothetical protein compare
BWI76_RS22115 +1.4 1.6 S-ribosylhomocysteine lyase compare
BWI76_RS20025 +1.4 3.6 HAMP domain-containing histidine kinase compare
BWI76_RS10380 +1.4 1.4 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS17195 +1.3 3.0 hypothetical protein compare
BWI76_RS14725 +1.3 1.0 HxlR family transcriptional regulator compare
BWI76_RS19550 +1.3 1.6 phospho-cellobiase compare
BWI76_RS12745 +1.3 1.4 putative prophage membrane protein compare
BWI76_RS10720 +1.3 2.5 putrescine importer compare
BWI76_RS21940 +1.3 1.8 SDR family oxidoreductase compare
BWI76_RS23020 +1.3 2.0 cobalamin biosynthesis protein CbiQ compare
BWI76_RS14845 +1.3 1.2 hypothetical protein compare
BWI76_RS13220 +1.3 1.4 N-acetyltransferase compare
BWI76_RS05235 +1.3 1.4 hypothetical protein compare
BWI76_RS13310 +1.3 2.3 glucan biosynthesis protein D compare
BWI76_RS09720 +1.2 1.5 PTS ascorbate transporter subunit IIB compare
BWI76_RS11020 +1.2 2.3 oxidoreductase family, NAD-binding protein compare
BWI76_RS24070 +1.2 1.8 16S rRNA (uracil(1498)-N(3))-methyltransferase compare
BWI76_RS20785 +1.2 1.3 ethanolamine utilization protein EutJ compare
BWI76_RS24290 +1.2 1.2 membrane protein compare
BWI76_RS15860 +1.2 3.7 adenine-specific DNA methyltransferase compare
BWI76_RS08825 +1.2 2.2 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS20060 +1.2 1.6 o-succinylbenzoate synthase compare
BWI76_RS27915 +1.2 1.6 YceK/YidQ family lipoprotein compare
BWI76_RS16915 +1.2 1.4 alpha/beta hydrolase fold protein compare
BWI76_RS19700 +1.2 2.4 deoxyribonuclease IV compare
BWI76_RS25415 +1.2 3.7 GntR family transcriptional regulator compare
BWI76_RS18575 +1.2 1.9 transcriptional regulator compare
BWI76_RS18770 +1.2 1.2 DNA gyrase inhibitor compare
BWI76_RS03545 +1.2 2.0 QacE family quaternary ammonium compound efflux SMR transporter compare
BWI76_RS08350 +1.2 1.5 carboxylase compare
BWI76_RS04655 +1.2 2.5 shikimate dehydrogenase compare
BWI76_RS13630 +1.2 4.7 ABC transporter compare
BWI76_RS02885 +1.2 1.6 dihydroorotase compare
BWI76_RS25220 +1.2 1.7 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS02200 +1.2 1.4 phosphonate C-P lyase system protein PhnL compare
BWI76_RS18195 +1.2 1.5 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
BWI76_RS23320 +1.1 1.5 hypothetical protein compare
BWI76_RS03815 +1.1 1.8 hypothetical protein compare
BWI76_RS14870 +1.1 1.6 hypothetical protein compare
BWI76_RS06465 +1.1 1.4 IclR family transcriptional regulator compare
BWI76_RS15595 +1.1 2.0 hypothetical protein compare
BWI76_RS24330 +1.1 2.1 TIGR00156 family protein compare
BWI76_RS01855 +1.1 1.9 chorismate lyase compare
BWI76_RS06805 +1.1 1.1 primosomal replication protein N'' compare
BWI76_RS06290 +1.1 1.6 ACP phosphodiesterase compare
BWI76_RS15260 +1.1 1.4 hypothetical protein compare
BWI76_RS07025 +1.1 3.0 glycerate kinase II compare
BWI76_RS17300 +1.1 1.6 tRNA-Tyr compare
BWI76_RS14925 +1.1 1.8 ABC transporter substrate-binding protein compare
BWI76_RS10895 +1.1 2.2 phosphatase compare
BWI76_RS21075 +1.1 1.5 membrane protein compare
BWI76_RS14750 +1.1 1.2 transcriptional regulator compare
BWI76_RS24960 +1.1 1.8 N-acetyltransferase compare
BWI76_RS24350 +1.1 1.7 quinol monooxygenase compare
BWI76_RS21390 +1.1 2.5 thiol disulfide reductase thioredoxin compare
BWI76_RS07925 +1.1 2.4 hypothetical protein compare
BWI76_RS12515 +1.1 1.0 protease compare
BWI76_RS18240 +1.1 1.7 L-arabinose ABC transporter permease AraH compare
BWI76_RS01575 +1.1 1.9 endonuclease V compare
BWI76_RS19985 +1.0 1.6 MFS transporter compare
BWI76_RS11165 +1.0 1.3 beta-N-acetylhexosaminidase compare
BWI76_RS00375 +1.0 1.4 hypothetical protein compare
BWI76_RS11920 +1.0 1.4 hypothetical protein compare
BWI76_RS11515 +1.0 1.1 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS13575 +1.0 2.1 sugar binding transcriptional regulator, LacI family protein compare
BWI76_RS15720 +1.0 2.4 prophage protein NinE compare
BWI76_RS02245 +1.0 1.8 hypothetical protein compare
BWI76_RS26335 +1.0 1.5 ABC transporter ATP-binding protein compare
BWI76_RS16450 +1.0 2.2 fusaric acid resistance protein compare
BWI76_RS10310 +1.0 2.7 DNA-binding transcriptional regulator RamA compare
BWI76_RS15620 +1.0 1.5 hypothetical protein compare
BWI76_RS22840 +1.0 1.5 transposase compare
BWI76_RS00445 +1.0 1.6 PIN domain nuclease compare
BWI76_RS26355 +1.0 1.7 hypothetical protein compare
BWI76_RS07640 +1.0 1.3 short chain dehydrogenase compare
BWI76_RS27905 +1.0 1.2 heat-shock protein IbpB compare
BWI76_RS01540 +1.0 1.1 thiamine biosynthesis protein ThiS compare
BWI76_RS22110 +1.0 1.5 putative helix-turn-helix AraC-type transcriptional regulator compare
BWI76_RS16860 +1.0 3.0 acyl-CoA dehydrogenase compare
BWI76_RS08820 +1.0 1.9 molybdenum cofactor biosynthesis protein compare
BWI76_RS07500 +1.0 1.3 RND transporter MFP subunit compare
BWI76_RS26890 +1.0 1.2 hypothetical protein compare
BWI76_RS19470 +1.0 1.5 DNA-binding response regulator compare
BWI76_RS18410 +1.0 2.6 drug/metabolite exporter YedA compare
BWI76_RS07725 +1.0 0.8 iron-enterobactin transporter permease compare
BWI76_RS16640 +1.0 1.2 threonine transporter compare
BWI76_RS10725 +1.0 2.2 hypothetical protein compare
BWI76_RS08295 +1.0 2.1 hypothetical protein compare
BWI76_RS03700 +1.0 1.5 hypothetical protein compare
BWI76_RS24785 +1.0 2.9 DUF805 domain-containing protein compare
BWI76_RS14805 +0.9 2.0 hypothetical protein compare
BWI76_RS08925 +0.9 1.3 DNA-binding protein YbiB compare
BWI76_RS27425 +0.9 1.6 DNA-directed RNA polymerase subunit omega compare
BWI76_RS10055 +0.9 1.9 AraC family transcriptional regulator compare
BWI76_RS04140 +0.9 1.0 phosphopentomutase compare
BWI76_RS07765 +0.9 1.2 thioesterase compare
BWI76_RS13480 +0.9 1.2 XRE family transcriptional regulator compare
BWI76_RS03100 +0.9 1.2 protein iolH compare
BWI76_RS12110 +0.9 1.1 hypothetical protein compare
BWI76_RS04275 +0.9 2.0 molybdopterin adenylyltransferase compare
BWI76_RS13015 +0.9 3.6 LysR family transcriptional regulator compare
BWI76_RS16805 +0.9 1.1 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS19705 +0.9 2.4 kinase compare
BWI76_RS16660 +0.9 1.5 SfnB family sulfur acquisition oxidoreductase compare
BWI76_RS16900 +0.9 1.6 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS15695 +0.9 3.7 hypothetical protein compare
BWI76_RS20855 +0.9 1.1 hypothetical protein compare
BWI76_RS21850 +0.9 2.6 AraC family transcriptional regulator compare
BWI76_RS20390 +0.9 1.5 erythronate-4-phosphate dehydrogenase compare
BWI76_RS08305 +0.9 1.3 two-component sensor histidine kinase compare
BWI76_RS18515 +0.9 1.8 multidrug transporter AcrB compare
BWI76_RS11865 +0.9 2.2 phosphatase compare
BWI76_RS18745 +0.9 1.8 adenosylhomocysteinase compare
BWI76_RS12555 +0.9 1.0 hypothetical protein compare
BWI76_RS16420 +0.9 1.7 anhydro-N-acetylmuramic acid kinase compare
BWI76_RS21930 +0.9 2.4 LysR family transcriptional regulator compare
BWI76_RS00115 +0.9 1.8 6-phosphogluconate phosphatase compare
BWI76_RS16090 +0.9 1.1 two-component system response regulator DcuR compare
BWI76_RS13980 +0.9 1.1 hypothetical protein compare
BWI76_RS27395 +0.9 1.9 hypothetical protein compare
BWI76_RS04830 +0.9 2.3 type IV pilin biogenesis protein compare
BWI76_RS19375 +0.9 1.2 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS03800 +0.9 1.3 hypothetical protein compare
BWI76_RS01585 +0.9 3.7 transcriptional regulator compare
BWI76_RS19365 +0.9 0.8 ribulokinase compare
BWI76_RS07355 +0.9 1.9 TonB-dependent siderophore receptor compare
BWI76_RS01780 +0.9 2.0 SPFH domain / Band 7 family protein compare
BWI76_RS07515 +0.9 2.2 glutamate--cysteine ligase compare
BWI76_RS11150 +0.9 0.6 membrane protein compare
BWI76_RS16390 +0.9 1.1 dipeptide/tripeptide permease A compare
BWI76_RS11410 +0.9 1.1 leucine efflux protein compare
BWI76_RS10505 +0.9 0.9 putative guanine/xanthin permease compare
BWI76_RS00715 +0.9 1.7 two-component sensor histidine kinase compare
BWI76_RS08765 +0.9 1.8 8-amino-7-oxononanoate synthase compare
BWI76_RS11765 +0.9 2.7 bifunctional transporter/kinase compare
BWI76_RS19770 +0.9 1.5 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS00025 +0.9 0.6 hypothetical protein compare
BWI76_RS12815 +0.9 2.0 transcriptional regulator FeaR compare
BWI76_RS14200 +0.8 2.7 protocatechuate 4,5-dioxygenase compare
BWI76_RS16050 +0.8 2.0 malonate decarboxylase holo-ACP synthase compare
BWI76_RS24480 +0.8 1.5 undecaprenyl-diphosphatase compare
BWI76_RS11710 +0.8 1.0 nucleotide excision repair endonuclease compare
BWI76_RS10580 +0.8 2.0 amino acid ABC transporter permease compare
BWI76_RS26260 +0.8 2.4 hypothetical protein compare
BWI76_RS17785 +0.8 1.3 septum site-determining protein MinD compare
BWI76_RS25925 +0.8 2.1 hypothetical protein compare
BWI76_RS14775 +0.8 1.2 creatinine amidohydrolase compare
BWI76_RS04260 +0.8 2.7 peroxide stress protein YaaA compare
BWI76_RS06460 +0.8 1.1 shikimate dehydrogenase compare
BWI76_RS10730 +0.8 1.5 bifunctional glucose-1-phosphatase/inositol phosphatase compare
BWI76_RS23260 +0.8 1.8 prepilin-type cleavage/methylation domain-containing protein compare
BWI76_RS03525 +0.8 1.8 tryptophanyl-tRNA synthetase compare
BWI76_RS03190 +0.8 1.2 hypothetical protein compare
BWI76_RS21760 +0.8 1.3 SMP-30/gluconolactonase/LRE family protein compare
BWI76_RS01030 +0.8 1.7 cytosine/purine, uracil, thiamine, allantoin permease family protein compare
BWI76_RS23525 +0.8 1.9 EamA family transporter compare
BWI76_RS24955 +0.8 1.2 hypothetical protein compare
BWI76_RS03615 +0.8 1.6 putative transcriptional regulatory protein compare
BWI76_RS21905 +0.8 1.1 class II aldolase compare
BWI76_RS14900 +0.8 1.1 oxidoreductase compare
BWI76_RS15715 +0.8 1.6 putative ninG protein compare
BWI76_RS07705 +0.8 0.7 enterochelin esterase compare
BWI76_RS20465 +0.8 1.2 hypothetical protein compare
BWI76_RS03940 +0.8 3.0 alcohol dehydrogenase compare
BWI76_RS25485 +0.8 1.1 septum formation protein Maf compare


Specific Phenotypes

For 1 genes in this experiment