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Experiment set11IT085 for
Klebsiella michiganensis M5al
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RCH2_defined_Glucose_noNitrogen in EcoFAB_3.5mL
200 most detrimental genes:
gene
name
fitness
t score
description
BWI76
_RS22430
+3.1
1.6
manganese/iron transporter ATP-binding protein
compare
BWI76
_RS09450
+3.0
1.8
30S ribosomal protein S6--L-glutamate ligase
compare
BWI76
_RS26300
+2.7
1.6
glycerol-3-phosphate transporter permease
compare
BWI76
_RS19465
+2.6
4.9
hypothetical protein
compare
BWI76
_RS18070
+2.5
2.1
DNA polymerase III subunit epsilon
compare
BWI76
_RS18725
+2.5
1.8
hypothetical protein
compare
BWI76
_RS21165
+2.3
3.8
Fe-S cluster assembly transcriptional regulator IscR
compare
BWI76
_RS23025
+2.2
6.4
cobalt ABC transporter substrate-binding protein CbiN
compare
BWI76
_RS17750
+2.1
3.1
Na+/H+ antiporter NhaB
compare
BWI76
_RS14980
+2.1
1.8
hypothetical protein
compare
BWI76
_RS11980
+2.0
1.8
DeoR family transcriptional regulator
compare
BWI76
_RS07255
+2.0
2.0
hypothetical protein
compare
BWI76
_RS13135
+1.9
1.4
3-oxoadipyl-CoA thiolase
compare
BWI76
_RS05520
+1.8
2.0
hypothetical protein
compare
BWI76
_RS21685
+1.8
2.4
hypothetical protein
compare
BWI76
_RS03185
+1.6
4.1
CI repressor
compare
BWI76
_RS06250
+1.6
1.3
alpha-glycosidase
compare
BWI76
_RS17200
+1.6
2.2
hypothetical protein
compare
BWI76
_RS05430
+1.6
2.9
UbiE/COQ5 family methyltransferase
compare
BWI76
_RS10855
+1.6
1.5
RND family efflux transporter MFP subunit
compare
BWI76
_RS06735
+1.6
2.5
50S ribosomal protein L31
compare
BWI76
_RS00885
+1.5
2.2
tRNA (uridine(54)-C5)-methyltransferase TrmA
compare
BWI76
_RS11500
+1.5
2.2
D-hexose-6-phosphate mutarotase
compare
BWI76
_RS00725
+1.5
0.9
periplasmic repressor CpxP
compare
BWI76
_RS16000
+1.5
1.7
multidrug transporter subunit MdtI
compare
BWI76
_RS16850
+1.4
1.3
ABC transporter periplasmic substrate-binding protein
compare
BWI76
_RS13240
+1.4
1.5
hypothetical protein
compare
BWI76
_RS16580
+1.4
1.6
ubiquinol oxidase subunit II
compare
BWI76
_RS25870
+1.4
1.7
elongation factor Tu
compare
BWI76
_RS15920
+1.4
1.9
hypothetical protein
compare
BWI76
_RS24600
+1.4
2.0
dihydroxyacetone kinase
compare
BWI76
_RS23245
+1.4
2.1
hypothetical protein
compare
BWI76
_RS16300
+1.4
1.6
bifunctional beta-cystathionase/maltose regulon regulatory protein
compare
BWI76
_RS22510
+1.4
4.4
hypothetical protein
compare
BWI76
_RS15565
+1.4
1.4
hypothetical protein
compare
BWI76
_RS22115
+1.4
1.6
S-ribosylhomocysteine lyase
compare
BWI76
_RS20025
+1.4
3.6
HAMP domain-containing histidine kinase
compare
BWI76
_RS10380
+1.4
1.4
polar amino acid ABC transporter inner membrane subunit
compare
BWI76
_RS17195
+1.3
3.0
hypothetical protein
compare
BWI76
_RS14725
+1.3
1.0
HxlR family transcriptional regulator
compare
BWI76
_RS19550
+1.3
1.6
phospho-cellobiase
compare
BWI76
_RS12745
+1.3
1.4
putative prophage membrane protein
compare
BWI76
_RS10720
+1.3
2.5
putrescine importer
compare
BWI76
_RS21940
+1.3
1.8
SDR family oxidoreductase
compare
BWI76
_RS23020
+1.3
2.0
cobalamin biosynthesis protein CbiQ
compare
BWI76
_RS14845
+1.3
1.2
hypothetical protein
compare
BWI76
_RS13220
+1.3
1.4
N-acetyltransferase
compare
BWI76
_RS05235
+1.3
1.4
hypothetical protein
compare
BWI76
_RS13310
+1.3
2.3
glucan biosynthesis protein D
compare
BWI76
_RS09720
+1.2
1.5
PTS ascorbate transporter subunit IIB
compare
BWI76
_RS11020
+1.2
2.3
oxidoreductase family, NAD-binding protein
compare
BWI76
_RS24070
+1.2
1.8
16S rRNA (uracil(1498)-N(3))-methyltransferase
compare
BWI76
_RS20785
+1.2
1.3
ethanolamine utilization protein EutJ
compare
BWI76
_RS24290
+1.2
1.2
membrane protein
compare
BWI76
_RS15860
+1.2
3.7
adenine-specific DNA methyltransferase
compare
BWI76
_RS08825
+1.2
2.2
cyclic pyranopterin monophosphate synthase MoaC
compare
BWI76
_RS20060
+1.2
1.6
o-succinylbenzoate synthase
compare
BWI76
_RS27915
+1.2
1.6
YceK/YidQ family lipoprotein
compare
BWI76
_RS16915
+1.2
1.4
alpha/beta hydrolase fold protein
compare
BWI76
_RS19700
+1.2
2.4
deoxyribonuclease IV
compare
BWI76
_RS25415
+1.2
3.7
GntR family transcriptional regulator
compare
BWI76
_RS18575
+1.2
1.9
transcriptional regulator
compare
BWI76
_RS18770
+1.2
1.2
DNA gyrase inhibitor
compare
BWI76
_RS03545
+1.2
2.0
QacE family quaternary ammonium compound efflux SMR transporter
compare
BWI76
_RS08350
+1.2
1.5
carboxylase
compare
BWI76
_RS04655
+1.2
2.5
shikimate dehydrogenase
compare
BWI76
_RS13630
+1.2
4.7
ABC transporter
compare
BWI76
_RS02885
+1.2
1.6
dihydroorotase
compare
BWI76
_RS25220
+1.2
1.7
outer membrane lipid asymmetry maintenance protein MlaD
compare
BWI76
_RS02200
+1.2
1.4
phosphonate C-P lyase system protein PhnL
compare
BWI76
_RS18195
+1.2
1.5
tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB
compare
BWI76
_RS23320
+1.1
1.5
hypothetical protein
compare
BWI76
_RS03815
+1.1
1.8
hypothetical protein
compare
BWI76
_RS14870
+1.1
1.6
hypothetical protein
compare
BWI76
_RS06465
+1.1
1.4
IclR family transcriptional regulator
compare
BWI76
_RS15595
+1.1
2.0
hypothetical protein
compare
BWI76
_RS24330
+1.1
2.1
TIGR00156 family protein
compare
BWI76
_RS01855
+1.1
1.9
chorismate lyase
compare
BWI76
_RS06805
+1.1
1.1
primosomal replication protein N''
compare
BWI76
_RS06290
+1.1
1.6
ACP phosphodiesterase
compare
BWI76
_RS15260
+1.1
1.4
hypothetical protein
compare
BWI76
_RS07025
+1.1
3.0
glycerate kinase II
compare
BWI76
_RS17300
+1.1
1.6
tRNA-Tyr
compare
BWI76
_RS14925
+1.1
1.8
ABC transporter substrate-binding protein
compare
BWI76
_RS10895
+1.1
2.2
phosphatase
compare
BWI76
_RS21075
+1.1
1.5
membrane protein
compare
BWI76
_RS14750
+1.1
1.2
transcriptional regulator
compare
BWI76
_RS24960
+1.1
1.8
N-acetyltransferase
compare
BWI76
_RS24350
+1.1
1.7
quinol monooxygenase
compare
BWI76
_RS21390
+1.1
2.5
thiol disulfide reductase thioredoxin
compare
BWI76
_RS07925
+1.1
2.4
hypothetical protein
compare
BWI76
_RS12515
+1.1
1.0
protease
compare
BWI76
_RS18240
+1.1
1.7
L-arabinose ABC transporter permease AraH
compare
BWI76
_RS01575
+1.1
1.9
endonuclease V
compare
BWI76
_RS19985
+1.0
1.6
MFS transporter
compare
BWI76
_RS11165
+1.0
1.3
beta-N-acetylhexosaminidase
compare
BWI76
_RS00375
+1.0
1.4
hypothetical protein
compare
BWI76
_RS11920
+1.0
1.4
hypothetical protein
compare
BWI76
_RS11515
+1.0
1.1
peptide-methionine (R)-S-oxide reductase
compare
BWI76
_RS13575
+1.0
2.1
sugar binding transcriptional regulator, LacI family protein
compare
BWI76
_RS15720
+1.0
2.4
prophage protein NinE
compare
BWI76
_RS02245
+1.0
1.8
hypothetical protein
compare
BWI76
_RS26335
+1.0
1.5
ABC transporter ATP-binding protein
compare
BWI76
_RS16450
+1.0
2.2
fusaric acid resistance protein
compare
BWI76
_RS10310
+1.0
2.7
DNA-binding transcriptional regulator RamA
compare
BWI76
_RS15620
+1.0
1.5
hypothetical protein
compare
BWI76
_RS22840
+1.0
1.5
transposase
compare
BWI76
_RS00445
+1.0
1.6
PIN domain nuclease
compare
BWI76
_RS26355
+1.0
1.7
hypothetical protein
compare
BWI76
_RS07640
+1.0
1.3
short chain dehydrogenase
compare
BWI76
_RS27905
+1.0
1.2
heat-shock protein IbpB
compare
BWI76
_RS01540
+1.0
1.1
thiamine biosynthesis protein ThiS
compare
BWI76
_RS22110
+1.0
1.5
putative helix-turn-helix AraC-type transcriptional regulator
compare
BWI76
_RS16860
+1.0
3.0
acyl-CoA dehydrogenase
compare
BWI76
_RS08820
+1.0
1.9
molybdenum cofactor biosynthesis protein
compare
BWI76
_RS07500
+1.0
1.3
RND transporter MFP subunit
compare
BWI76
_RS26890
+1.0
1.2
hypothetical protein
compare
BWI76
_RS19470
+1.0
1.5
DNA-binding response regulator
compare
BWI76
_RS18410
+1.0
2.6
drug/metabolite exporter YedA
compare
BWI76
_RS07725
+1.0
0.8
iron-enterobactin transporter permease
compare
BWI76
_RS16640
+1.0
1.2
threonine transporter
compare
BWI76
_RS10725
+1.0
2.2
hypothetical protein
compare
BWI76
_RS08295
+1.0
2.1
hypothetical protein
compare
BWI76
_RS03700
+1.0
1.5
hypothetical protein
compare
BWI76
_RS24785
+1.0
2.9
DUF805 domain-containing protein
compare
BWI76
_RS14805
+0.9
2.0
hypothetical protein
compare
BWI76
_RS08925
+0.9
1.3
DNA-binding protein YbiB
compare
BWI76
_RS27425
+0.9
1.6
DNA-directed RNA polymerase subunit omega
compare
BWI76
_RS10055
+0.9
1.9
AraC family transcriptional regulator
compare
BWI76
_RS04140
+0.9
1.0
phosphopentomutase
compare
BWI76
_RS07765
+0.9
1.2
thioesterase
compare
BWI76
_RS13480
+0.9
1.2
XRE family transcriptional regulator
compare
BWI76
_RS03100
+0.9
1.2
protein iolH
compare
BWI76
_RS12110
+0.9
1.1
hypothetical protein
compare
BWI76
_RS04275
+0.9
2.0
molybdopterin adenylyltransferase
compare
BWI76
_RS13015
+0.9
3.6
LysR family transcriptional regulator
compare
BWI76
_RS16805
+0.9
1.1
basic amino acid ABC transporter substrate-binding protein
compare
BWI76
_RS19705
+0.9
2.4
kinase
compare
BWI76
_RS16660
+0.9
1.5
SfnB family sulfur acquisition oxidoreductase
compare
BWI76
_RS16900
+0.9
1.6
4-hydroxy-2-oxovalerate aldolase
compare
BWI76
_RS15695
+0.9
3.7
hypothetical protein
compare
BWI76
_RS20855
+0.9
1.1
hypothetical protein
compare
BWI76
_RS21850
+0.9
2.6
AraC family transcriptional regulator
compare
BWI76
_RS20390
+0.9
1.5
erythronate-4-phosphate dehydrogenase
compare
BWI76
_RS08305
+0.9
1.3
two-component sensor histidine kinase
compare
BWI76
_RS18515
+0.9
1.8
multidrug transporter AcrB
compare
BWI76
_RS11865
+0.9
2.2
phosphatase
compare
BWI76
_RS18745
+0.9
1.8
adenosylhomocysteinase
compare
BWI76
_RS12555
+0.9
1.0
hypothetical protein
compare
BWI76
_RS16420
+0.9
1.7
anhydro-N-acetylmuramic acid kinase
compare
BWI76
_RS21930
+0.9
2.4
LysR family transcriptional regulator
compare
BWI76
_RS00115
+0.9
1.8
6-phosphogluconate phosphatase
compare
BWI76
_RS16090
+0.9
1.1
two-component system response regulator DcuR
compare
BWI76
_RS13980
+0.9
1.1
hypothetical protein
compare
BWI76
_RS27395
+0.9
1.9
hypothetical protein
compare
BWI76
_RS04830
+0.9
2.3
type IV pilin biogenesis protein
compare
BWI76
_RS19375
+0.9
1.2
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase
compare
BWI76
_RS03800
+0.9
1.3
hypothetical protein
compare
BWI76
_RS01585
+0.9
3.7
transcriptional regulator
compare
BWI76
_RS19365
+0.9
0.8
ribulokinase
compare
BWI76
_RS07355
+0.9
1.9
TonB-dependent siderophore receptor
compare
BWI76
_RS01780
+0.9
2.0
SPFH domain / Band 7 family protein
compare
BWI76
_RS07515
+0.9
2.2
glutamate--cysteine ligase
compare
BWI76
_RS11150
+0.9
0.6
membrane protein
compare
BWI76
_RS16390
+0.9
1.1
dipeptide/tripeptide permease A
compare
BWI76
_RS11410
+0.9
1.1
leucine efflux protein
compare
BWI76
_RS10505
+0.9
0.9
putative guanine/xanthin permease
compare
BWI76
_RS00715
+0.9
1.7
two-component sensor histidine kinase
compare
BWI76
_RS08765
+0.9
1.8
8-amino-7-oxononanoate synthase
compare
BWI76
_RS11765
+0.9
2.7
bifunctional transporter/kinase
compare
BWI76
_RS19770
+0.9
1.5
bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase
compare
BWI76
_RS00025
+0.9
0.6
hypothetical protein
compare
BWI76
_RS12815
+0.9
2.0
transcriptional regulator FeaR
compare
BWI76
_RS14200
+0.8
2.7
protocatechuate 4,5-dioxygenase
compare
BWI76
_RS16050
+0.8
2.0
malonate decarboxylase holo-ACP synthase
compare
BWI76
_RS24480
+0.8
1.5
undecaprenyl-diphosphatase
compare
BWI76
_RS11710
+0.8
1.0
nucleotide excision repair endonuclease
compare
BWI76
_RS10580
+0.8
2.0
amino acid ABC transporter permease
compare
BWI76
_RS26260
+0.8
2.4
hypothetical protein
compare
BWI76
_RS17785
+0.8
1.3
septum site-determining protein MinD
compare
BWI76
_RS25925
+0.8
2.1
hypothetical protein
compare
BWI76
_RS14775
+0.8
1.2
creatinine amidohydrolase
compare
BWI76
_RS04260
+0.8
2.7
peroxide stress protein YaaA
compare
BWI76
_RS06460
+0.8
1.1
shikimate dehydrogenase
compare
BWI76
_RS10730
+0.8
1.5
bifunctional glucose-1-phosphatase/inositol phosphatase
compare
BWI76
_RS23260
+0.8
1.8
prepilin-type cleavage/methylation domain-containing protein
compare
BWI76
_RS03525
+0.8
1.8
tryptophanyl-tRNA synthetase
compare
BWI76
_RS03190
+0.8
1.2
hypothetical protein
compare
BWI76
_RS21760
+0.8
1.3
SMP-30/gluconolactonase/LRE family protein
compare
BWI76
_RS01030
+0.8
1.7
cytosine/purine, uracil, thiamine, allantoin permease family protein
compare
BWI76
_RS23525
+0.8
1.9
EamA family transporter
compare
BWI76
_RS24955
+0.8
1.2
hypothetical protein
compare
BWI76
_RS03615
+0.8
1.6
putative transcriptional regulatory protein
compare
BWI76
_RS21905
+0.8
1.1
class II aldolase
compare
BWI76
_RS14900
+0.8
1.1
oxidoreductase
compare
BWI76
_RS15715
+0.8
1.6
putative ninG protein
compare
BWI76
_RS07705
+0.8
0.7
enterochelin esterase
compare
BWI76
_RS20465
+0.8
1.2
hypothetical protein
compare
BWI76
_RS03940
+0.8
3.0
alcohol dehydrogenase
compare
BWI76
_RS25485
+0.8
1.1
septum formation protein Maf
compare
Specific Phenotypes
For 1 genes in this experiment