Experiment set11IT080 for Klebsiella michiganensis M5al

Compare to:

D-Glucose 20 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18935 -7.7 -5.3 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS18955 -7.6 -5.2 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS07065 -7.3 -5.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23220 -7.1 -4.9 amino-acid N-acetyltransferase compare
BWI76_RS18950 -7.0 -4.9 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS11965 -6.8 -4.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS09755 -6.5 -4.5 phosphoserine transaminase compare
BWI76_RS18925 -6.5 -4.5 histidinol dehydrogenase compare
BWI76_RS02995 -6.5 -6.3 aspartate carbamoyltransferase compare
BWI76_RS04675 -6.4 -6.2 3-isopropylmalate dehydrogenase compare
BWI76_RS04685 -6.4 -7.6 putative leucine operon leader peptide compare
BWI76_RS04255 -6.3 -4.3 threonine synthase compare
BWI76_RS09760 -6.1 -5.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS11860 -6.1 -7.2 anthranilate synthase component I compare
BWI76_RS23920 -6.1 -4.2 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS05840 -6.0 -4.1 glutamate 5-kinase compare
BWI76_RS18920 -5.8 -4.0 ATP phosphoribosyltransferase compare
BWI76_RS00835 -5.8 -10.4 phosphoenolpyruvate carboxylase compare
BWI76_RS11855 -5.7 -6.8 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS01655 -5.6 -7.8 homoserine O-succinyltransferase compare
BWI76_RS18940 -5.6 -3.9 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS25645 -5.6 -5.4 shikimate dehydrogenase compare
BWI76_RS08385 -5.5 -3.4 citrate (Si)-synthase compare
BWI76_RS27385 -5.5 -5.4 orotate phosphoribosyltransferase compare
BWI76_RS04670 -5.5 -8.4 3-isopropylmalate dehydratase large subunit compare
BWI76_RS22760 -5.4 -7.4 sulfite reductase subunit beta compare
BWI76_RS04250 -5.3 -7.2 homoserine kinase compare
BWI76_RS20355 -5.1 -3.8 colicin V production protein compare
BWI76_RS04665 -5.1 -17.1 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04470 -5.0 -8.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS05835 -4.9 -3.4 gamma-glutamyl-phosphate reductase compare
BWI76_RS21475 -4.9 -6.6 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS00980 -4.9 -9.4 PLP-dependent threonine dehydratase compare
BWI76_RS00785 -4.8 -6.6 cystathionine gamma-synthase compare
BWI76_RS09910 -4.8 -17.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11850 -4.7 -7.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04245 -4.7 -13.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS01800 -4.7 -3.2 glucose-6-phosphate isomerase compare
BWI76_RS26085 -4.7 -3.2 3-dehydroquinate synthase compare
BWI76_RS01210 -4.7 -2.9 tyrosine recombinase XerC compare
BWI76_RS24285 -4.7 -8.3 cystathionine beta-lyase compare
BWI76_RS18930 -4.7 -4.2 histidinol-phosphate transaminase compare
BWI76_RS23360 -4.7 -3.2 diaminopimelate decarboxylase compare
BWI76_RS21265 -4.6 -14.1 phosphoribosylformylglycinamidine synthase compare
BWI76_RS00850 -4.6 -7.2 acetylglutamate kinase compare
BWI76_RS01610 -4.6 -7.9 phosphoribosylamine--glycine ligase compare
BWI76_RS20970 -4.5 -1.8 phosphoribosylglycinamide formyltransferase compare
BWI76_RS00805 -4.5 -2.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS01615 -4.5 -10.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00845 -4.5 -8.8 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00855 -4.5 -7.2 argininosuccinate lyase compare
BWI76_RS00990 -4.4 -7.1 ketol-acid reductoisomerase compare
BWI76_RS04465 -4.4 -4.8 carbamoyl-phosphate synthase small subunit compare
BWI76_RS20350 -4.3 -6.4 amidophosphoribosyltransferase compare
BWI76_RS22765 -4.3 -10.4 sulfite reductase subunit alpha compare
BWI76_RS00975 -4.3 -8.9 dihydroxy-acid dehydratase compare
BWI76_RS26055 -4.2 -8.3 siroheme synthase compare
BWI76_RS04160 -4.2 -5.6 phosphoserine phosphatase compare
BWI76_RS00965 -4.1 -1.6 acetolactate synthase 2 small subunit compare
BWI76_RS11840 -4.1 -5.0 tryptophan synthase subunit alpha compare
BWI76_RS00985 -3.9 -7.1 transcriptional regulator IlvY compare
BWI76_RS07070 -3.9 -4.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS04680 -3.8 -9.4 2-isopropylmalate synthase compare
BWI76_RS11845 -3.7 -2.4 tryptophan synthase subunit beta compare
BWI76_RS04510 -3.7 -2.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS04240 -3.7 -1.7 thr operon leader peptide compare
BWI76_RS03010 -3.7 -7.6 ornithine carbamoyltransferase compare
BWI76_RS25320 -3.6 -7.4 glutamate synthase compare
BWI76_RS20895 -3.6 -4.7 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS25115 -3.5 -5.2 argininosuccinate synthase compare
BWI76_RS04645 -3.5 -6.3 3-dehydroquinase compare
BWI76_RS27390 -3.5 -4.1 ribonuclease PH compare
BWI76_RS23365 -3.4 -7.1 LysR family transcriptional regulator compare
BWI76_RS22755 -3.4 -4.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS22690 -3.4 -3.0 adenylyl-sulfate kinase compare
BWI76_RS26570 -3.4 -3.2 anion permease compare
BWI76_RS23230 -3.4 -2.3 exodeoxyribonuclease V subunit beta compare
BWI76_RS26000 -3.3 -8.2 aspartate aminotransferase family protein compare
BWI76_RS09645 -3.3 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS21465 -3.2 -2.9 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS20435 -3.0 -1.6 chorismate synthase compare
BWI76_RS20965 -2.7 -3.9 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS02735 -2.7 -4.7 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS01350 -2.6 -1.4 NAD(P)H-flavin reductase compare
BWI76_RS22805 -2.5 -7.7 GTP diphosphokinase compare
BWI76_RS21450 -2.5 -3.3 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS23240 -2.5 -4.1 exonuclease V subunit gamma compare
BWI76_RS25315 -2.5 -9.0 glutamate synthase large subunit compare
BWI76_RS00390 -2.4 -3.8 two-component system sensor histidine kinase NtrB compare
BWI76_RS21370 -2.3 -1.9 ATP-dependent RNA helicase SrmB compare
BWI76_RS00440 -2.3 -2.2 CopG family transcriptional regulator compare
BWI76_RS20230 -2.3 -1.6 hypothetical protein compare
BWI76_RS10990 -2.3 -1.3 dihydroorotase compare
BWI76_RS23480 -2.1 -9.9 EAL domain-containing protein compare
BWI76_RS05450 -2.1 -1.7 ribonuclease HI compare
BWI76_RS05015 -2.1 -2.5 transcriptional regulator compare
BWI76_RS25070 -2.1 -1.6 hypothetical protein compare
BWI76_RS20650 -2.1 -1.4 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS01325 -2.0 -2.5 twin-arginine translocase subunit TatB compare
BWI76_RS09655 -2.0 -3.2 leucine-responsive regulatory protein compare
BWI76_RS06530 -2.0 -3.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS20440 -1.9 -2.0 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS18580 -1.9 -1.6 hypothetical protein compare
BWI76_RS26460 -1.9 -5.8 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS09660 -1.9 -2.5 DNA translocase FtsK compare
BWI76_RS00180 -1.9 -1.7 F0F1 ATP synthase subunit epsilon compare
BWI76_RS24575 -1.9 -1.3 hypothetical protein compare
BWI76_RS00960 -1.9 -6.3 acetolactate synthase 2 catalytic subunit compare
BWI76_RS18755 -1.8 -1.4 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS06680 -1.8 -1.3 hypothetical protein compare
BWI76_RS02985 -1.8 -4.1 reactive intermediate/imine deaminase compare
BWI76_RS12090 -1.8 -1.3 HNH endonuclease compare
BWI76_RS21140 -1.7 -2.9 molecular chaperone HscA compare
BWI76_RS26075 -1.7 -4.3 DNA adenine methylase compare
BWI76_RS25060 -1.7 -2.8 lipoprotein NlpI compare
BWI76_RS27820 -1.7 -1.9 ilvB operon leader peptide IvbL compare
BWI76_RS01185 -1.7 -1.9 adenylate cyclase compare
BWI76_RS07785 -1.7 -2.2 transcriptional regulator compare
BWI76_RS11820 -1.6 -1.1 short-chain dehydrogenase/reductase SDR compare
BWI76_RS11520 -1.6 -1.4 hypothetical protein compare
BWI76_RS14835 -1.6 -1.0 hypothetical protein compare
BWI76_RS18165 -1.6 -1.3 NUDIX pyrophosphatase compare
BWI76_RS11430 -1.6 -1.0 lipoprotein compare
BWI76_RS02990 -1.6 -3.3 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS25960 -1.6 -4.5 NUDIX hydrolase compare
BWI76_RS01885 -1.6 -1.2 CsbD family protein compare
BWI76_RS05200 -1.6 -2.5 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS06765 -1.6 -3.1 transcriptional regulator compare
BWI76_RS21505 -1.5 -1.4 hypothetical protein compare
BWI76_RS21070 -1.5 -1.3 outer membrane protein assembly factor BamB compare
BWI76_RS15835 -1.5 -1.0 hypothetical protein compare
BWI76_RS11130 -1.5 -7.3 PTS glucose transporter subunit IIBC compare
BWI76_RS00345 -1.5 -2.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS20730 -1.5 -1.6 hypothetical protein compare
BWI76_RS13435 -1.5 -1.6 hypothetical protein compare
BWI76_RS17945 -1.5 -1.4 hypothetical protein compare
BWI76_RS15680 -1.5 -4.0 hypothetical protein compare
BWI76_RS26065 -1.4 -1.7 phosphoglycolate phosphatase compare
BWI76_RS11835 -1.4 -1.8 putative regulatory protein MarR compare
BWI76_RS20640 -1.4 -3.6 cysteine synthase A compare
BWI76_RS21565 -1.4 -1.1 outer membrane protein assembly factor BamE compare
BWI76_RS20565 -1.4 -1.6 hypothetical protein compare
BWI76_RS26455 -1.3 -2.9 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS21580 -1.3 -1.8 SsrA-binding protein compare
BWI76_RS08665 -1.3 -2.7 6-phosphogluconolactonase compare
BWI76_RS22695 -1.3 -3.7 sulfate adenylyltransferase compare
BWI76_RS06465 -1.3 -1.3 IclR family transcriptional regulator compare
BWI76_RS00940 -1.3 -3.0 transcriptional regulator HdfR compare
BWI76_RS25425 -1.3 -1.3 arginine repressor compare
BWI76_RS01995 -1.3 -1.1 AraC family transcriptional regulator compare
BWI76_RS25480 -1.2 -2.0 ribonuclease E/G compare
BWI76_RS11235 -1.2 -1.1 hypothetical protein compare
BWI76_RS05640 -1.2 -2.8 GntR family transcriptional regulator compare
BWI76_RS27430 -1.2 -0.9 (p)ppGpp synthetase compare
BWI76_RS27940 -1.2 -1.0 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
BWI76_RS13095 -1.2 -1.4 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS00385 -1.2 -5.5 nitrogen assimilation regulatory protein compare
BWI76_RS19495 -1.2 -1.1 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS17920 -1.2 -1.9 23S rRNA (guanine(745)-N(1))-methyltransferase compare
BWI76_RS11435 -1.2 -1.1 hypothetical protein compare
BWI76_RS06295 -1.2 -2.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS15605 -1.2 -2.1 hypothetical protein compare
BWI76_RS16150 -1.2 -1.5 IclR family transcriptional regulator compare
BWI76_RS04515 -1.1 -1.3 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS20695 -1.1 -1.8 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS20610 -1.1 -1.6 LysR family transcriptional regulator compare
BWI76_RS12590 -1.1 -3.1 helix-turn-helix-type transcriptional regulator compare
BWI76_RS13480 -1.1 -1.3 XRE family transcriptional regulator compare
BWI76_RS11255 -1.1 -1.3 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS02745 -1.1 -1.0 hypothetical protein compare
BWI76_RS15825 -1.1 -1.8 hypothetical protein compare
BWI76_RS00415 -1.1 -2.6 glucose-1-phosphatase compare
BWI76_RS26805 -1.1 -2.5 cellulose biosynthesis protein BcsF compare
BWI76_RS00400 -1.1 -0.6 glutamine synthetase compare
BWI76_RS25335 -1.1 -2.8 stringent starvation protein A compare
BWI76_RS05260 -1.1 -1.5 chaperone compare
BWI76_RS12155 -1.1 -2.6 hypothetical protein compare
BWI76_RS11015 -1.1 -1.5 hypothetical protein compare
BWI76_RS21480 -1.1 -3.2 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS01200 -1.1 -1.4 diaminopimelate epimerase compare
BWI76_RS01275 -1.1 -2.5 LysR family transcriptional regulator compare
BWI76_RS23140 -1.0 -1.5 carboxysome shell protein compare
BWI76_RS09970 -1.0 -2.0 porin OmpA compare
BWI76_RS03660 -1.0 -3.0 hypothetical protein compare
BWI76_RS27310 -1.0 -4.3 glycosyltransferase compare
BWI76_RS01890 -1.0 -2.7 transcriptional regulator Zur compare
BWI76_RS15650 -1.0 -2.6 gp5 compare
BWI76_RS08330 -1.0 -1.2 hypothetical protein compare
BWI76_RS16500 -1.0 -1.7 superoxide dismutase [Fe] compare
BWI76_RS06185 -1.0 -4.3 shikimate kinase II compare
BWI76_RS18870 -1.0 -1.0 protein NifZ compare
BWI76_RS04305 -1.0 -0.9 molecular chaperone DnaJ compare
BWI76_RS13965 -1.0 -2.0 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS11410 -1.0 -1.3 leucine efflux protein compare
BWI76_RS16645 -1.0 -1.3 DeoR family transcriptional regulator compare
BWI76_RS13980 -1.0 -1.2 hypothetical protein compare
BWI76_RS06340 -1.0 -0.9 hypothetical protein compare
BWI76_RS23265 -1.0 -1.4 hypothetical protein compare
BWI76_RS10950 -1.0 -2.2 MFS transporter compare
BWI76_RS10935 -1.0 -2.5 glucan biosynthesis glucosyltransferase H compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in carbon source experiments

For carbon source D-Glucose across organisms