Experiment set11IT078 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxyinosine 5 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS04675 -7.3 -5.0 3-isopropylmalate dehydrogenase compare
BWI76_RS18950 -7.3 -4.9 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS18930 -7.0 -5.7 histidinol-phosphate transaminase compare
BWI76_RS05840 -6.2 -4.3 glutamate 5-kinase compare
BWI76_RS18920 -6.1 -4.1 ATP phosphoribosyltransferase compare
BWI76_RS00855 -6.1 -5.9 argininosuccinate lyase compare
BWI76_RS08385 -5.8 -3.3 citrate (Si)-synthase compare
BWI76_RS04645 -5.6 -6.7 3-dehydroquinase compare
BWI76_RS27385 -5.4 -6.4 orotate phosphoribosyltransferase compare
BWI76_RS04255 -5.3 -9.5 threonine synthase compare
BWI76_RS04160 -5.2 -6.7 phosphoserine phosphatase compare
BWI76_RS05835 -5.2 -3.6 gamma-glutamyl-phosphate reductase compare
BWI76_RS11850 -4.9 -8.6 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26085 -4.9 -3.0 3-dehydroquinate synthase compare
BWI76_RS04670 -4.9 -10.4 3-isopropylmalate dehydratase large subunit compare
BWI76_RS23365 -4.9 -5.6 LysR family transcriptional regulator compare
BWI76_RS18955 -4.8 -5.0 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS18925 -4.7 -6.1 histidinol dehydrogenase compare
BWI76_RS01655 -4.7 -6.4 homoserine O-succinyltransferase compare
BWI76_RS23920 -4.7 -7.8 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04130 -4.7 -7.5 2-deoxyribose-5-phosphate aldolase compare
BWI76_RS18935 -4.7 -9.6 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23220 -4.6 -6.8 amino-acid N-acetyltransferase compare
BWI76_RS04470 -4.5 -10.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS18940 -4.5 -5.7 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS10990 -4.4 -2.2 dihydroorotase compare
BWI76_RS04245 -4.4 -14.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11860 -4.3 -7.7 anthranilate synthase component I compare
BWI76_RS00835 -4.3 -11.8 phosphoenolpyruvate carboxylase compare
BWI76_RS02815 -4.3 -2.9 fructose-bisphosphatase class I compare
BWI76_RS00965 -4.3 -1.5 acetolactate synthase 2 small subunit compare
BWI76_RS09755 -4.2 -9.6 phosphoserine transaminase compare
BWI76_RS21475 -4.2 -3.8 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS11840 -4.1 -5.8 tryptophan synthase subunit alpha compare
BWI76_RS00985 -4.1 -6.3 transcriptional regulator IlvY compare
BWI76_RS00980 -4.1 -10.1 PLP-dependent threonine dehydratase compare
BWI76_RS21465 -4.0 -3.5 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS03010 -4.0 -7.5 ornithine carbamoyltransferase compare
BWI76_RS04685 -3.9 -9.1 putative leucine operon leader peptide compare
BWI76_RS04465 -3.9 -5.5 carbamoyl-phosphate synthase small subunit compare
BWI76_RS11845 -3.8 -2.8 tryptophan synthase subunit beta compare
BWI76_RS04665 -3.8 -15.9 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00975 -3.6 -6.0 dihydroxy-acid dehydratase compare
BWI76_RS09910 -3.5 -14.5 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS04680 -3.5 -10.3 2-isopropylmalate synthase compare
BWI76_RS04250 -3.5 -5.3 homoserine kinase compare
BWI76_RS24285 -3.4 -5.3 cystathionine beta-lyase compare
BWI76_RS11855 -3.4 -4.1 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04510 -3.4 -3.2 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS00850 -3.3 -6.8 acetylglutamate kinase compare
BWI76_RS00990 -3.3 -6.2 ketol-acid reductoisomerase compare
BWI76_RS00785 -3.3 -5.8 cystathionine gamma-synthase compare
BWI76_RS20435 -3.2 -1.6 chorismate synthase compare
BWI76_RS02995 -3.2 -6.1 aspartate carbamoyltransferase compare
BWI76_RS09760 -3.1 -2.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS23240 -3.0 -4.5 exonuclease V subunit gamma compare
BWI76_RS04140 -3.0 -4.8 phosphopentomutase compare
BWI76_RS00805 -2.9 -2.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS00845 -2.9 -7.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS01385 -2.9 -3.7 potassium transporter compare
BWI76_RS05200 -2.9 -3.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS22765 -2.9 -8.7 sulfite reductase subunit alpha compare
BWI76_RS17290 -2.9 -4.5 formyltetrahydrofolate deformylase compare
BWI76_RS25115 -2.9 -5.0 argininosuccinate synthase compare
BWI76_RS11965 -2.9 -2.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS23360 -2.8 -2.1 diaminopimelate decarboxylase compare
BWI76_RS22760 -2.8 -6.8 sulfite reductase subunit beta compare
BWI76_RS04240 -2.7 -2.9 thr operon leader peptide compare
BWI76_RS27390 -2.7 -3.6 ribonuclease PH compare
BWI76_RS09660 -2.7 -3.0 DNA translocase FtsK compare
BWI76_RS01210 -2.6 -2.5 tyrosine recombinase XerC compare
BWI76_RS25600 -2.6 -1.3 tRNA-Thr compare
BWI76_RS01615 -2.6 -7.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS06185 -2.5 -6.3 shikimate kinase II compare
BWI76_RS04305 -2.5 -1.5 molecular chaperone DnaJ compare
BWI76_RS11335 -2.4 -2.1 tautomerase compare
BWI76_RS26055 -2.4 -6.6 siroheme synthase compare
BWI76_RS14075 -2.2 -1.6 TetR family transcriptional regulator compare
BWI76_RS08380 -2.1 -2.2 endonuclease VIII compare
BWI76_RS17525 -2.0 -1.6 XshC-Cox1-family protein compare
BWI76_RS15825 -2.0 -2.5 hypothetical protein compare
BWI76_RS20155 -2.0 -2.2 NADH-quinone oxidoreductase subunit I compare
BWI76_RS09635 -2.0 -2.6 amino acid ABC transporter ATP-binding protein compare
BWI76_RS17805 -1.9 -1.3 membrane protein compare
BWI76_RS04145 -1.9 -2.2 purine-nucleoside phosphorylase compare
BWI76_RS13090 -1.9 -2.5 phenylacetate-CoA oxygenase subunit PaaA compare
BWI76_RS04705 -1.9 -5.9 DNA-binding transcriptional regulator FruR compare
BWI76_RS09640 -1.9 -1.8 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS12090 -1.8 -2.6 HNH endonuclease compare
BWI76_RS04135 -1.8 -3.9 thymidine phosphorylase compare
BWI76_RS27820 -1.8 -1.5 ilvB operon leader peptide IvbL compare
BWI76_RS21285 -1.7 -1.9 HAD family hydrolase compare
BWI76_RS01630 -1.7 -1.2 16S ribosomal RNA compare
BWI76_RS21345 -1.7 -2.5 sigma-E factor regulatory protein RseB compare
BWI76_RS11435 -1.7 -1.5 hypothetical protein compare
BWI76_RS16520 -1.7 -2.5 Bcr/CflA family multidrug efflux MFS transporter compare
BWI76_RS07780 -1.6 -1.2 hypothetical protein compare
BWI76_RS22690 -1.6 -2.8 adenylyl-sulfate kinase compare
BWI76_RS05260 -1.6 -1.9 chaperone compare
BWI76_RS15290 -1.6 -1.6 transcriptional regulator compare
BWI76_RS23480 -1.6 -7.5 EAL domain-containing protein compare
BWI76_RS18755 -1.6 -1.3 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS12125 -1.5 -2.3 hypothetical protein compare
BWI76_RS11520 -1.5 -1.3 hypothetical protein compare
BWI76_RS23230 -1.5 -3.1 exodeoxyribonuclease V subunit beta compare
BWI76_RS16200 -1.5 -2.4 NAD(P) transhydrogenase subunit beta compare
BWI76_RS20440 -1.5 -1.5 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS01185 -1.5 -2.1 adenylate cyclase compare
BWI76_RS09970 -1.4 -3.2 porin OmpA compare
BWI76_RS02735 -1.4 -3.5 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS05945 -1.4 -3.3 amino acid ABC transporter permease compare
BWI76_RS25920 -1.4 -1.3 peptidylprolyl isomerase compare
BWI76_RS09645 -1.4 -1.3 thioredoxin-disulfide reductase compare
BWI76_RS27425 -1.4 -1.6 DNA-directed RNA polymerase subunit omega compare
BWI76_RS00505 -1.4 -2.3 PTS system, sorbose-specific IIB component compare
BWI76_RS22880 -1.4 -3.1 L-serine ammonia-lyase compare
BWI76_RS25375 -1.4 -2.0 hypothetical protein compare
BWI76_RS25870 -1.4 -1.2 elongation factor Tu compare
BWI76_RS22755 -1.4 -3.6 phosphoadenosine phosphosulfate reductase compare
BWI76_RS01200 -1.4 -1.4 diaminopimelate epimerase compare
BWI76_RS21140 -1.4 -2.6 molecular chaperone HscA compare
BWI76_RS22240 -1.3 -6.4 transcriptional regulator compare
BWI76_RS03880 -1.3 -2.1 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS24170 -1.3 -5.4 nucleoside permease compare
BWI76_RS05005 -1.3 -2.1 polynucleotide adenylyltransferase compare
BWI76_RS16515 -1.3 -1.0 LysR family transcriptional regulator compare
BWI76_RS27075 -1.3 -3.9 IclR family transcriptional regulator compare
BWI76_RS23140 -1.3 -1.2 carboxysome shell protein compare
BWI76_RS24110 -1.3 -1.8 YggU family protein compare
BWI76_RS09190 -1.3 -2.0 hypothetical protein compare
BWI76_RS00355 -1.3 -2.2 DNA polymerase I compare
BWI76_RS10510 -1.3 -2.0 OHCU decarboxylase compare
BWI76_RS04815 -1.3 -2.8 cell division protein ZapD compare
BWI76_RS22450 -1.2 -1.8 selenoprotein W-related protein compare
BWI76_RS01890 -1.2 -2.6 transcriptional regulator Zur compare
BWI76_RS14625 -1.2 -1.4 protein TolA compare
BWI76_RS01905 -1.2 -2.3 envelope stress response protein PspG compare
BWI76_RS09650 -1.2 -5.3 hypothetical protein compare
BWI76_RS03415 -1.2 -3.3 LacI family transcriptional regulator compare
BWI76_RS23125 -1.2 -1.6 propanediol dehydratase small subunit compare
BWI76_RS15830 -1.2 -2.6 hypothetical protein compare
BWI76_RS08525 -1.2 -2.2 colicin transporter compare
BWI76_RS06190 -1.2 -2.1 hypothetical protein compare
BWI76_RS08360 -1.2 -3.4 LamB/YcsF family protein compare
BWI76_RS03080 -1.2 -2.7 (Fe-S)-cluster assembly protein compare
BWI76_RS11700 -1.2 -1.3 hypothetical protein compare
BWI76_RS09655 -1.2 -3.5 leucine-responsive regulatory protein compare
BWI76_RS26175 -1.2 -2.7 DeoR/GlpR family transcriptional regulator compare
BWI76_RS19010 -1.2 -2.6 polysaccharide pyruvyl transferase yvff compare
BWI76_RS25960 -1.2 -2.3 NUDIX hydrolase compare
BWI76_RS08395 -1.2 -1.4 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS00400 -1.2 -0.6 glutamine synthetase compare
BWI76_RS16470 -1.2 -1.2 transcriptional repressor NemR compare
BWI76_RS13545 -1.1 -1.0 N-acetyltransferase compare
BWI76_RS03015 -1.1 -2.3 RNase E inhibitor protein compare
BWI76_RS04715 -1.1 -1.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS20170 -1.1 -2.5 NADH-quinone oxidoreductase subunit F compare
BWI76_RS09830 -1.1 -1.6 tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM compare
BWI76_RS20910 -1.1 -2.0 glycine cleavage system transcriptional repressor compare
BWI76_RS08535 -1.1 -1.6 translocation protein TolB compare
BWI76_RS06595 -1.1 -1.8 hypothetical protein compare
BWI76_RS23580 -1.1 -1.9 hypothetical protein compare
BWI76_RS13025 -1.1 -2.1 histidine phosphatase family protein compare
BWI76_RS01350 -1.1 -0.9 NAD(P)H-flavin reductase compare
BWI76_RS13050 -1.1 -1.5 transcriptional regulator compare
BWI76_RS09030 -1.1 -2.7 transpeptidase compare
BWI76_RS20270 -1.0 -2.9 hypothetical protein compare
BWI76_RS15980 -1.0 -1.6 lysine transporter LysE compare
BWI76_RS23760 -1.0 -1.0 tRNA-Gly compare
BWI76_RS03180 -1.0 -2.1 phage transcriptional regulator, AlpA compare
BWI76_RS16195 -1.0 -1.5 hypothetical protein compare
BWI76_RS01940 -1.0 -2.1 hypothetical protein compare
BWI76_RS07740 -1.0 -1.2 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS15835 -1.0 -0.7 hypothetical protein compare
BWI76_RS01095 -1.0 -1.4 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS20060 -1.0 -2.7 o-succinylbenzoate synthase compare
BWI76_RS24850 -1.0 -3.3 DeoR family transcriptional regulator compare
BWI76_RS16190 -1.0 -2.3 universal stress protein UspE compare
BWI76_RS20145 -1.0 -1.3 NADH-quinone oxidoreductase subunit K compare
BWI76_RS25320 -1.0 -3.7 glutamate synthase compare
BWI76_RS12150 -1.0 -2.1 DNA damage-inducible protein I compare
BWI76_RS07790 -1.0 -1.6 plasmid stabilization protein compare
BWI76_RS02985 -1.0 -3.1 reactive intermediate/imine deaminase compare
BWI76_RS15685 -1.0 -1.9 hypothetical protein compare
BWI76_RS17770 -1.0 -1.5 isomerase/hydrolase compare
BWI76_RS21480 -1.0 -3.0 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS01060 -1.0 -3.8 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase compare
BWI76_RS08370 -1.0 -1.5 membrane protein compare
BWI76_RS27605 -1.0 -1.5 hypothetical protein compare
BWI76_RS02580 -1.0 -0.9 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS25245 -0.9 -2.0 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase compare
BWI76_RS19685 -0.9 -3.0 lysine transporter compare
BWI76_RS12420 -0.9 -0.8 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS24635 -0.9 -2.6 autoinducer-2 (AI-2) modifying protein LsrG compare
BWI76_RS20390 -0.9 -1.0 erythronate-4-phosphate dehydrogenase compare
BWI76_RS20130 -0.9 -2.7 NADH-quinone oxidoreductase subunit N compare
BWI76_RS22475 -0.9 -1.7 heme ABC transporter ATP-binding protein compare
BWI76_RS12055 -0.9 -2.1 DNA single-strand annealing protein RecT-like protein compare
BWI76_RS21165 -0.9 -1.1 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS00440 -0.9 -1.3 CopG family transcriptional regulator compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source 2'-Deoxyinosine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxyinosine across organisms