Experiment set11IT078 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxyinosine 5 mM carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS25065 +2.8 7.1 polyribonucleotide nucleotidyltransferase compare
BWI76_RS25060 +2.7 12.0 lipoprotein NlpI compare
BWI76_RS17975 +2.4 9.1 tail-specific protease compare
BWI76_RS25225 +2.1 2.8 ABC transporter permease compare
BWI76_RS20360 +1.7 2.1 cell division protein DedD compare
BWI76_RS15990 +1.6 6.7 serine protease compare
BWI76_RS12170 +1.5 1.4 hypothetical protein compare
BWI76_RS00765 +1.4 8.1 DNA-binding transcriptional regulator CytR compare
BWI76_RS23015 +1.3 2.3 cobalt transporter ATP-binding subunit compare
BWI76_RS10755 +1.3 1.7 pyrimidine utilization flavin reductase protein F compare
BWI76_RS09150 +1.3 4.2 DNA-binding transcriptional repressor DeoR compare
BWI76_RS10745 +1.3 1.6 hypothetical protein compare
BWI76_RS07640 +1.3 1.8 short chain dehydrogenase compare
BWI76_RS26470 +1.3 4.1 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS13955 +1.3 1.4 hypothetical protein compare
BWI76_RS18125 +1.2 5.0 murein DD-endopeptidase MepM compare
BWI76_RS22935 +1.2 2.5 L-fucose mutarotase compare
BWI76_RS07730 +1.2 1.7 iron-enterobactin transporter membrane protein compare
BWI76_RS18575 +1.2 1.8 transcriptional regulator compare
BWI76_RS18780 +1.1 1.5 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS15740 +1.1 1.5 HNH endonuclease compare
BWI76_RS14005 +1.1 2.0 TetR family transcriptional regulator compare
BWI76_RS14415 +1.1 3.2 transcriptional regulator, TetR family protein compare
BWI76_RS14770 +1.1 1.7 PTS IIA 2 domain protein compare
BWI76_RS20750 +1.1 1.5 carboxysome structural protein EutK compare
BWI76_RS19470 +1.1 2.2 DNA-binding response regulator compare
BWI76_RS26410 +1.0 1.4 membrane protein compare
BWI76_RS05335 +1.0 2.3 copper homeostasis/adhesion lipoprotein NlpE compare
BWI76_RS20720 +1.0 1.2 hypothetical protein compare
BWI76_RS07820 +1.0 1.7 S-methyl-5-thioribose kinase compare
BWI76_RS09560 +1.0 1.3 DoxX family membrane protein compare
BWI76_RS27745 +1.0 2.0 PTS sugar transporter subunit IIB compare
BWI76_RS01330 +1.0 3.1 twin-arginine translocase subunit TatC compare
BWI76_RS09615 +1.0 1.1 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS16260 +1.0 1.7 two-component sensor histidine kinase compare
BWI76_RS19535 +0.9 2.0 putative integral membrane protein compare
BWI76_RS07185 +0.9 1.3 hypothetical protein compare
BWI76_RS11370 +0.9 2.2 iron-dicitrate transporter subunit FecD compare
BWI76_RS18815 +0.9 2.6 nitrogenase molybdenum-iron protein alpha chain compare
BWI76_RS26620 +0.9 1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS25070 +0.9 1.5 hypothetical protein compare
BWI76_RS10580 +0.9 2.8 amino acid ABC transporter permease compare
BWI76_RS06245 +0.9 3.8 proline-specific permease ProY compare
BWI76_RS14835 +0.9 1.3 hypothetical protein compare
BWI76_RS21235 +0.9 1.1 hypothetical protein compare
BWI76_RS20930 +0.9 1.2 arsenate reductase (glutaredoxin) compare
BWI76_RS13325 +0.9 1.9 dicarboxylate transporter/tellurite-resistance protein TehA compare
BWI76_RS19870 +0.9 2.8 malate:quinone oxidoreductase compare
BWI76_RS07705 +0.9 2.2 enterochelin esterase compare
BWI76_RS05465 +0.9 1.0 amidohydrolase compare
BWI76_RS11810 +0.9 1.4 outer membrane protein OmpW compare
BWI76_RS11455 +0.8 2.4 AraC family transcriptional regulator compare
BWI76_RS05955 +0.8 3.2 ABC transporter compare
BWI76_RS13880 +0.8 3.1 lysine transporter LysE compare
BWI76_RS16900 +0.8 1.5 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS13240 +0.8 1.1 hypothetical protein compare
BWI76_RS12045 +0.8 1.2 hypothetical protein compare
BWI76_RS01135 +0.8 2.3 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS16920 +0.8 1.6 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS03105 +0.8 1.1 myo-inosose-2 dehydratase compare
BWI76_RS14460 +0.8 2.6 MurR/RpiR family transcriptional regulator compare
BWI76_RS16805 +0.8 1.3 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS07260 +0.8 3.2 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS20475 +0.8 2.2 phospholipid-binding lipoprotein MlaA compare
BWI76_RS20895 +0.8 3.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS23255 +0.8 1.5 prepilin-type cleavage/methylation domain-containing protein compare
BWI76_RS17980 +0.8 2.6 RNA chaperone ProQ compare
BWI76_RS17225 +0.8 3.8 oligopeptide ABC transporter ATP-binding protein OppD compare
BWI76_RS01560 +0.8 2.4 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS23555 +0.8 2.6 type 1 major fimbrial subunit precursor compare
BWI76_RS21460 +0.8 1.1 translation inhibitor protein RaiA compare
BWI76_RS03800 +0.8 2.1 hypothetical protein compare
BWI76_RS25365 +0.8 4.4 serine endoprotease DegQ compare
BWI76_RS09730 +0.8 0.8 pyruvate formate lyase 1-activating protein compare
BWI76_RS08650 +0.8 2.0 molybdate ABC transporter permease compare
BWI76_RS15185 +0.8 1.6 N-acetyltransferase compare
BWI76_RS23690 +0.8 0.6 putative glyoxalase/bleomycin resistance protein/dioxygenase compare
BWI76_RS03585 +0.8 3.3 ethanolamine utilization protein EutN compare
BWI76_RS09255 +0.7 1.4 hypothetical protein compare
BWI76_RS08520 +0.7 1.2 colicin transporter TolQ compare
BWI76_RS23820 +0.7 1.9 flavodoxin FldB compare
BWI76_RS15735 +0.7 1.7 hypothetical protein compare
BWI76_RS20650 +0.7 1.5 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS00590 +0.7 2.3 hypothetical protein compare
BWI76_RS21390 +0.7 1.8 thiol disulfide reductase thioredoxin compare
BWI76_RS22430 +0.7 1.7 manganese/iron transporter ATP-binding protein compare
BWI76_RS10725 +0.7 1.1 hypothetical protein compare
BWI76_RS11430 +0.7 0.8 lipoprotein compare
BWI76_RS26270 +0.7 2.5 N-acetyltransferase compare
BWI76_RS08805 +0.7 2.7 gluconeogenesis factor compare
BWI76_RS12865 +0.7 3.6 acetylornithine deacetylase compare
BWI76_RS22050 +0.7 2.0 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI compare
BWI76_RS08765 +0.7 1.2 8-amino-7-oxononanoate synthase compare
BWI76_RS23020 +0.7 0.8 cobalamin biosynthesis protein CbiQ compare
BWI76_RS15800 +0.7 2.1 transcriptional regulator compare
BWI76_RS21310 +0.7 0.8 DNA repair protein RecO compare
BWI76_RS09590 +0.7 2.9 ATP-dependent OLD family endonuclease compare
BWI76_RS00865 +0.7 2.0 DNA-binding transcriptional regulator OxyR compare
BWI76_RS12235 +0.7 1.3 hypothetical protein compare
BWI76_RS08825 +0.7 1.6 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS15210 +0.7 2.4 LysR family transcriptional regulator compare
BWI76_RS09860 +0.7 1.4 hypothetical protein compare
BWI76_RS20040 +0.7 2.4 tricarboxylic transport membrane protein compare
BWI76_RS12425 +0.7 3.5 hypothetical protein compare
BWI76_RS04215 +0.7 3.5 DNA-binding response regulator compare
BWI76_RS16040 +0.7 1.8 biotin-independent malonate decarboxylase subunit gamma compare
BWI76_RS11110 +0.7 1.8 cell division protein YceG compare
BWI76_RS13180 +0.7 1.3 multidrug transporter EmrA compare
BWI76_RS09360 +0.7 1.7 hypothetical protein compare
BWI76_RS05700 +0.7 2.3 coenzyme F420-dependent NADP oxidoreductase compare
BWI76_RS14505 +0.7 1.1 salicylate synthase Irp9 compare
BWI76_RS24725 +0.7 2.0 altronate hydrolase compare
BWI76_RS01285 +0.7 3.4 amino acid ABC transporter substrate-binding protein compare
BWI76_RS13020 +0.7 2.4 NmrA family protein compare
BWI76_RS15600 +0.7 1.5 hypothetical protein compare
BWI76_RS22425 +0.7 1.9 metal ABC transporter substrate-binding protein compare
BWI76_RS06785 +0.7 2.1 DNA-binding transcriptional repressor AcrR compare
BWI76_RS04095 +0.7 1.7 dUMP phosphatase compare
BWI76_RS16395 +0.7 2.1 glutathione S-transferase compare
BWI76_RS00710 +0.7 1.5 6-N-hydroxylaminopurine resistance protein compare
BWI76_RS08545 +0.7 2.3 cell division protein CpoB compare
BWI76_RS15205 +0.7 2.3 succinate-semialdehyde dehydrogenase compare
BWI76_RS04060 +0.6 1.1 hypothetical protein compare
BWI76_RS10585 +0.6 1.7 amino acid ABC transporter ATP-binding protein compare
BWI76_RS08800 +0.6 2.9 phosphoethanolamine transferase EptA compare
BWI76_RS16690 +0.6 1.3 peptide ABC transporter permease compare
BWI76_RS20340 +0.6 1.6 histidine ABC transporter substrate-binding protein HisJ compare
BWI76_RS12855 +0.6 1.3 enamine deaminase RidA compare
BWI76_RS00885 +0.6 2.4 tRNA (uridine(54)-C5)-methyltransferase TrmA compare
BWI76_RS01935 +0.6 0.9 thiamin phosphate synthase compare
BWI76_RS25220 +0.6 1.8 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS15785 +0.6 2.3 replication protein compare
BWI76_RS03925 +0.6 2.2 N-acetyltransferase GCN5 compare
BWI76_RS26325 +0.6 2.6 altronate hydrolase compare
BWI76_RS01600 +0.6 2.2 sensor protein ZraS compare
BWI76_RS01540 +0.6 0.5 thiamine biosynthesis protein ThiS compare
BWI76_RS09520 +0.6 1.5 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS17565 +0.6 1.0 hypothetical protein compare
BWI76_RS21075 +0.6 0.8 membrane protein compare
BWI76_RS19500 +0.6 2.8 osmoprotectant uptake system permease compare
BWI76_RS11900 +0.6 0.9 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS20735 +0.6 1.9 N-acetylmuramoyl-L-alanine amidase compare
BWI76_RS09220 +0.6 2.0 hypothetical protein compare
BWI76_RS24105 +0.6 1.7 resistance protein compare
BWI76_RS03170 +0.6 1.8 hypothetical protein compare
BWI76_RS13755 +0.6 0.9 hypothetical protein compare
BWI76_RS19110 +0.6 2.5 hypothetical protein compare
BWI76_RS13380 +0.6 1.2 hypothetical protein compare
BWI76_RS11665 +0.6 2.5 exodeoxyribonuclease III compare
BWI76_RS12860 +0.6 0.8 hypothetical protein compare
BWI76_RS16060 +0.6 1.9 LysR family transcriptional regulator compare
BWI76_RS06285 +0.6 2.6 peroxiredoxin compare
BWI76_RS15410 +0.6 1.8 N-acetyltransferase compare
BWI76_RS07350 +0.6 1.5 alcohol dehydrogenase compare
BWI76_RS05075 +0.6 0.6 type II secretion system protein GspG compare
BWI76_RS08970 +0.6 1.2 glutamine ABC transporter permease GlnP compare
BWI76_RS10650 +0.6 1.5 PTS fructose-like transporter subunit EIIB compare
BWI76_RS08275 +0.6 0.9 LexA regulated protein compare
BWI76_RS21755 +0.6 1.9 hypothetical protein compare
BWI76_RS03810 +0.6 2.9 GTPase compare
BWI76_RS11820 +0.6 0.6 short-chain dehydrogenase/reductase SDR compare
BWI76_RS02180 +0.6 0.7 hypothetical protein compare
BWI76_RS25215 +0.6 1.7 phospholipid-binding protein MlaC compare
BWI76_RS18025 +0.6 2.8 spore coat U domain-containing protein compare
BWI76_RS18005 +0.6 1.4 hypothetical protein compare
BWI76_RS22940 +0.6 1.9 DNA-binding transcriptional activator FucR compare
BWI76_RS25000 +0.6 0.9 malonate decarboxylase acyl carrier protein compare
BWI76_RS07520 +0.6 2.8 ABC transporter substrate-binding protein compare
BWI76_RS20410 +0.6 2.7 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC compare
BWI76_RS16760 +0.6 1.6 lipase compare
BWI76_RS18065 +0.6 1.3 DNA polymerase III subunit theta compare
BWI76_RS10770 +0.6 1.5 pyrimidine utilization protein C compare
BWI76_RS16400 +0.6 1.5 pyridoxal kinase compare
BWI76_RS18550 +0.6 0.9 tRNA-Asn compare
BWI76_RS19345 +0.6 1.8 D-arabinitol 4-dehydrogenase compare
BWI76_RS10060 +0.6 0.8 acylphosphatase compare
BWI76_RS13130 +0.6 1.2 phenylacetic acid degradation protein PaaD compare
BWI76_RS04100 +0.6 1.4 peptide chain release factor 3 compare
BWI76_RS08840 +0.6 0.7 hypothetical protein compare
BWI76_RS20810 +0.6 2.2 ethanolamine utilization cobalamin adenosyltransferase compare
BWI76_RS21995 +0.6 1.4 transcriptional regulator compare
BWI76_RS19790 +0.6 2.3 putative binding-protein-dependent transporter compare
BWI76_RS13660 +0.6 2.0 nitrate reductase subunit beta compare
BWI76_RS18735 +0.6 2.6 tautomerase family protein compare
BWI76_RS19695 +0.6 1.2 membrane protein compare
BWI76_RS22855 +0.6 1.5 hypothetical protein compare
BWI76_RS19310 +0.6 1.2 ABC transporter permease compare
BWI76_RS22645 +0.6 2.8 RNA polymerase sigma factor RpoS compare
BWI76_RS06740 +0.6 2.2 50S ribosomal protein L36 compare
BWI76_RS23510 +0.6 1.8 transcriptional regulator compare
BWI76_RS09600 +0.6 3.3 macrolide ABC transporter permease/ATP-binding protein MacB compare
BWI76_RS14065 +0.6 0.7 hypothetical protein compare
BWI76_RS13420 +0.6 1.3 ABC transporter permease compare
BWI76_RS02050 +0.6 0.5 CidA/LrgA family protein compare
BWI76_RS16640 +0.6 1.4 threonine transporter compare
BWI76_RS00750 +0.6 1.8 ATP-dependent protease ATP-binding subunit HslU compare
BWI76_RS05360 +0.5 2.2 methionine ABC transporter permease compare
BWI76_RS21350 +0.5 1.3 anti-RNA polymerase sigma factor SigE compare
BWI76_RS11935 +0.5 2.2 YmiA family putative membrane protein compare
BWI76_RS27940 +0.5 1.2 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source 2'-Deoxyinosine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxyinosine across organisms