Experiment set11IT077 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxyinosine 10 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -8.5 -5.4 histidinol-phosphate transaminase compare
BWI76_RS09755 -7.0 -4.8 phosphoserine transaminase compare
BWI76_RS00855 -6.7 -4.7 argininosuccinate lyase compare
BWI76_RS21475 -6.7 -6.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04465 -6.5 -4.5 carbamoyl-phosphate synthase small subunit compare
BWI76_RS21465 -6.4 -6.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS24285 -6.3 -7.4 cystathionine beta-lyase compare
BWI76_RS04670 -6.2 -8.5 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04255 -6.2 -7.4 threonine synthase compare
BWI76_RS00785 -6.2 -4.3 cystathionine gamma-synthase compare
BWI76_RS04685 -6.1 -11.6 putative leucine operon leader peptide compare
BWI76_RS00835 -6.0 -11.5 phosphoenolpyruvate carboxylase compare
BWI76_RS08385 -5.9 -3.5 citrate (Si)-synthase compare
BWI76_RS01210 -5.9 -4.6 tyrosine recombinase XerC compare
BWI76_RS02815 -5.6 -3.7 fructose-bisphosphatase class I compare
BWI76_RS18955 -5.6 -5.5 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00845 -5.6 -9.3 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00805 -5.5 -3.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS23920 -5.5 -6.5 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS01655 -5.4 -6.9 homoserine O-succinyltransferase compare
BWI76_RS04245 -5.4 -14.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS23365 -5.4 -5.9 LysR family transcriptional regulator compare
BWI76_RS25115 -5.3 -8.7 argininosuccinate synthase compare
BWI76_RS04510 -5.3 -3.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS04665 -5.2 -20.7 3-isopropylmalate dehydratase small subunit compare
BWI76_RS18920 -5.2 -3.8 ATP phosphoribosyltransferase compare
BWI76_RS05840 -5.2 -6.1 glutamate 5-kinase compare
BWI76_RS00980 -5.1 -10.4 PLP-dependent threonine dehydratase compare
BWI76_RS04130 -5.1 -5.9 2-deoxyribose-5-phosphate aldolase compare
BWI76_RS11855 -5.1 -6.0 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS04470 -5.1 -10.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS23360 -5.0 -3.5 diaminopimelate decarboxylase compare
BWI76_RS02995 -4.9 -9.6 aspartate carbamoyltransferase compare
BWI76_RS04645 -4.9 -8.1 3-dehydroquinase compare
BWI76_RS00990 -4.7 -8.0 ketol-acid reductoisomerase compare
BWI76_RS11840 -4.6 -5.3 tryptophan synthase subunit alpha compare
BWI76_RS04675 -4.5 -7.6 3-isopropylmalate dehydrogenase compare
BWI76_RS10990 -4.5 -2.4 dihydroorotase compare
BWI76_RS18935 -4.5 -4.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS09910 -4.4 -14.9 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11845 -4.4 -1.8 tryptophan synthase subunit beta compare
BWI76_RS11860 -4.4 -6.7 anthranilate synthase component I compare
BWI76_RS00965 -4.3 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS04160 -4.2 -8.6 phosphoserine phosphatase compare
BWI76_RS11850 -4.1 -7.7 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00850 -4.1 -8.4 acetylglutamate kinase compare
BWI76_RS05835 -4.1 -3.6 gamma-glutamyl-phosphate reductase compare
BWI76_RS04680 -4.1 -10.7 2-isopropylmalate synthase compare
BWI76_RS04250 -4.1 -6.7 homoserine kinase compare
BWI76_RS03010 -4.1 -6.6 ornithine carbamoyltransferase compare
BWI76_RS00975 -4.0 -9.3 dihydroxy-acid dehydratase compare
BWI76_RS27390 -4.0 -5.1 ribonuclease PH compare
BWI76_RS27385 -3.9 -6.2 orotate phosphoribosyltransferase compare
BWI76_RS18925 -3.9 -3.6 histidinol dehydrogenase compare
BWI76_RS18950 -3.8 -3.0 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS09645 -3.8 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS00985 -3.7 -8.1 transcriptional regulator IlvY compare
BWI76_RS18940 -3.7 -6.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS09760 -3.7 -3.5 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS22765 -3.7 -10.9 sulfite reductase subunit alpha compare
BWI76_RS23220 -3.6 -6.5 amino-acid N-acetyltransferase compare
BWI76_RS22760 -3.6 -9.2 sulfite reductase subunit beta compare
BWI76_RS11965 -3.4 -3.8 orotidine-5'-phosphate decarboxylase compare
BWI76_RS22755 -3.3 -6.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS20435 -3.2 -1.7 chorismate synthase compare
BWI76_RS02530 -3.1 -3.0 tRNA dimethylallyltransferase compare
BWI76_RS05200 -3.0 -3.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS15825 -3.0 -3.2 hypothetical protein compare
BWI76_RS16520 -2.9 -7.2 Bcr/CflA family multidrug efflux MFS transporter compare
BWI76_RS01200 -2.9 -2.9 diaminopimelate epimerase compare
BWI76_RS09660 -2.9 -3.3 DNA translocase FtsK compare
BWI76_RS04240 -2.9 -3.2 thr operon leader peptide compare
BWI76_RS01615 -2.8 -8.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS01185 -2.6 -1.8 adenylate cyclase compare
BWI76_RS04140 -2.6 -3.3 phosphopentomutase compare
BWI76_RS24900 -2.5 -2.6 DeoR family transcriptional regulator compare
BWI76_RS17290 -2.5 -3.5 formyltetrahydrofolate deformylase compare
BWI76_RS23240 -2.5 -4.6 exonuclease V subunit gamma compare
BWI76_RS04145 -2.4 -3.0 purine-nucleoside phosphorylase compare
BWI76_RS04955 -2.4 -2.4 hypoxanthine phosphoribosyltransferase compare
BWI76_RS16315 -2.4 -2.1 SirA-like protein compare
BWI76_RS16515 -2.3 -2.1 LysR family transcriptional regulator compare
BWI76_RS06015 -2.2 -2.0 hypothetical protein compare
BWI76_RS20640 -2.2 -6.2 cysteine synthase A compare
BWI76_RS21140 -2.2 -2.8 molecular chaperone HscA compare
BWI76_RS25280 -2.2 -2.5 RNase adaptor protein RapZ compare
BWI76_RS06185 -2.2 -7.8 shikimate kinase II compare
BWI76_RS08395 -2.1 -2.2 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS02735 -2.1 -4.8 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS25600 -2.1 -1.3 tRNA-Thr compare
BWI76_RS21675 -2.0 -1.4 hypothetical protein compare
BWI76_RS08535 -2.0 -2.5 translocation protein TolB compare
BWI76_RS26055 -1.9 -4.7 siroheme synthase compare
BWI76_RS22690 -1.8 -3.1 adenylyl-sulfate kinase compare
BWI76_RS12090 -1.8 -3.1 HNH endonuclease compare
BWI76_RS03080 -1.8 -3.7 (Fe-S)-cluster assembly protein compare
BWI76_RS04305 -1.8 -1.5 molecular chaperone DnaJ compare
BWI76_RS04705 -1.8 -4.1 DNA-binding transcriptional regulator FruR compare
BWI76_RS26085 -1.8 -1.4 3-dehydroquinate synthase compare
BWI76_RS04135 -1.7 -4.9 thymidine phosphorylase compare
BWI76_RS07595 -1.7 -2.8 putative oxidoreductase compare
BWI76_RS09655 -1.7 -3.6 leucine-responsive regulatory protein compare
BWI76_RS27075 -1.7 -5.4 IclR family transcriptional regulator compare
BWI76_RS20440 -1.7 -2.0 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS27820 -1.7 -2.2 ilvB operon leader peptide IvbL compare
BWI76_RS11700 -1.6 -1.7 hypothetical protein compare
BWI76_RS21580 -1.6 -1.9 SsrA-binding protein compare
BWI76_RS23480 -1.6 -8.4 EAL domain-containing protein compare
BWI76_RS15850 -1.6 -1.7 DUF1317 domain-containing protein compare
BWI76_RS03415 -1.6 -5.7 LacI family transcriptional regulator compare
BWI76_RS13250 -1.6 -1.5 cytochrome b561 compare
BWI76_RS15835 -1.6 -1.1 hypothetical protein compare
BWI76_RS20230 -1.6 -1.7 hypothetical protein compare
BWI76_RS25960 -1.6 -4.0 NUDIX hydrolase compare
BWI76_RS17370 -1.5 -2.6 nitrate transporter NasD compare
BWI76_RS09970 -1.5 -4.8 porin OmpA compare
BWI76_RS11335 -1.5 -1.9 tautomerase compare
BWI76_RS13095 -1.5 -1.9 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS20380 -1.5 -1.4 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS22240 -1.4 -4.3 transcriptional regulator compare
BWI76_RS09625 -1.4 -1.5 hypothetical protein compare
BWI76_RS08750 -1.4 -1.5 kinase inhibitor compare
BWI76_RS08380 -1.4 -1.8 endonuclease VIII compare
BWI76_RS23230 -1.4 -3.5 exodeoxyribonuclease V subunit beta compare
BWI76_RS06465 -1.4 -1.5 IclR family transcriptional regulator compare
BWI76_RS24955 -1.4 -2.2 hypothetical protein compare
BWI76_RS09640 -1.3 -2.0 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS24170 -1.3 -4.7 nucleoside permease compare
BWI76_RS20145 -1.3 -1.8 NADH-quinone oxidoreductase subunit K compare
BWI76_RS22840 -1.3 -1.7 transposase compare
BWI76_RS08605 -1.3 -1.3 phosphoglyceromutase compare
BWI76_RS24850 -1.3 -4.3 DeoR family transcriptional regulator compare
BWI76_RS23355 -1.3 -3.9 LacI family transcriptional regulator compare
BWI76_RS25320 -1.3 -6.0 glutamate synthase compare
BWI76_RS02610 -1.2 -4.2 transcriptional regulator compare
BWI76_RS00400 -1.2 -0.7 glutamine synthetase compare
BWI76_RS13685 -1.2 -2.3 IclR family transcriptional regulator compare
BWI76_RS07675 -1.2 -4.6 DeoR family transcriptional regulator compare
BWI76_RS26875 -1.2 -2.2 dipeptide ABC transporter permease DppC compare
BWI76_RS20130 -1.2 -3.8 NADH-quinone oxidoreductase subunit N compare
BWI76_RS02985 -1.2 -4.2 reactive intermediate/imine deaminase compare
BWI76_RS16360 -1.2 -1.4 electron transport complex subunit RsxB compare
BWI76_RS17765 -1.2 -2.7 hypothetical protein compare
BWI76_RS05235 -1.2 -1.1 hypothetical protein compare
BWI76_RS08405 -1.2 -2.2 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS19010 -1.2 -2.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS04050 -1.1 -2.2 hydroxamate siderophore iron reductase FhuF compare
BWI76_RS15225 -1.1 -3.3 DeoR family transcriptional regulator compare
BWI76_RS25645 -1.1 -3.5 shikimate dehydrogenase compare
BWI76_RS15830 -1.1 -2.3 hypothetical protein compare
BWI76_RS05165 -1.1 -2.4 cobalamin-binding protein compare
BWI76_RS16275 -1.1 -1.9 fumarate hydratase FumA compare
BWI76_RS03880 -1.1 -3.8 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS00355 -1.1 -2.0 DNA polymerase I compare
BWI76_RS22420 -1.1 -2.0 LacI family transcriptional regulator compare
BWI76_RS06470 -1.1 -1.7 hypothetical protein compare
BWI76_RS15810 -1.1 -4.7 hypothetical protein compare
BWI76_RS16200 -1.1 -1.9 NAD(P) transhydrogenase subunit beta compare
BWI76_RS04715 -1.1 -1.4 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS12420 -1.1 -1.0 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS06340 -1.1 -1.0 hypothetical protein compare
BWI76_RS17180 -1.1 -2.5 hypothetical protein compare
BWI76_RS16895 -1.0 -1.7 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS21505 -1.0 -1.2 hypothetical protein compare
BWI76_RS05005 -1.0 -1.9 polynucleotide adenylyltransferase compare
BWI76_RS08230 -1.0 -1.9 hypothetical protein compare
BWI76_RS20650 -1.0 -1.7 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS09420 -1.0 -1.8 hypothetical protein compare
BWI76_RS12470 -1.0 -1.3 thiosulfate sulfurtransferase PspE compare
BWI76_RS26175 -1.0 -3.4 DeoR/GlpR family transcriptional regulator compare
BWI76_RS08360 -1.0 -2.9 LamB/YcsF family protein compare
BWI76_RS09635 -1.0 -1.1 amino acid ABC transporter ATP-binding protein compare
BWI76_RS11635 -1.0 -1.3 ABC transporter compare
BWI76_RS27170 -1.0 -4.1 MltR family transcriptional regulator compare
BWI76_RS27475 -1.0 -5.5 regulatory protein GntR family protein compare
BWI76_RS06485 -1.0 -1.5 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS08515 -1.0 -1.7 acyl-CoA thioesterase YbgC compare
BWI76_RS14265 -1.0 -3.2 LysR family transcriptional regulator compare
BWI76_RS01125 -1.0 -3.3 4-alpha-L-fucosyltransferase compare
BWI76_RS20910 -0.9 -2.1 glycine cleavage system transcriptional repressor compare
BWI76_RS01380 -0.9 -2.3 YigZ family protein compare
BWI76_RS07465 -0.9 -2.1 TetR family transcriptional regulator compare
BWI76_RS25315 -0.9 -5.3 glutamate synthase large subunit compare
BWI76_RS07970 -0.9 -1.8 hypothetical protein compare
BWI76_RS23055 -0.9 -2.7 cobalamin biosynthesis protein CbiG compare
BWI76_RS19935 -0.9 -1.3 hypothetical protein compare
BWI76_RS26000 -0.9 -2.8 aspartate aminotransferase family protein compare
BWI76_RS06730 -0.9 -1.4 lac repressor compare
BWI76_RS21100 -0.9 -2.4 nucleoside-diphosphate kinase compare
BWI76_RS01090 -0.9 -2.1 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS20155 -0.9 -1.3 NADH-quinone oxidoreductase subunit I compare
BWI76_RS01220 -0.9 -3.7 DNA-dependent helicase II compare
BWI76_RS12345 -0.9 -2.4 nitrite transporter compare
BWI76_RS24605 -0.9 -4.7 dihydroxyacetone kinase subunit DhaM compare
BWI76_RS15845 -0.9 -0.8 hypothetical protein compare
BWI76_RS24635 -0.9 -1.6 autoinducer-2 (AI-2) modifying protein LsrG compare
BWI76_RS20270 -0.9 -2.3 hypothetical protein compare
BWI76_RS20785 -0.9 -0.9 ethanolamine utilization protein EutJ compare
BWI76_RS08205 -0.9 -2.4 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS01115 -0.9 -2.2 dTDP-4-amino-4,6-dideoxygalactose transaminase compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source 2'-Deoxyinosine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxyinosine across organisms