Experiment set11IT077 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxyinosine 10 mM carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS17975 +3.1 13.2 tail-specific protease compare
BWI76_RS25065 +2.6 9.7 polyribonucleotide nucleotidyltransferase compare
BWI76_RS25060 +2.5 12.1 lipoprotein NlpI compare
BWI76_RS25225 +2.2 3.1 ABC transporter permease compare
BWI76_RS07640 +1.8 3.9 short chain dehydrogenase compare
BWI76_RS12170 +1.4 2.2 hypothetical protein compare
BWI76_RS00765 +1.3 6.2 DNA-binding transcriptional regulator CytR compare
BWI76_RS24080 +1.3 3.3 DUF179 domain-containing protein compare
BWI76_RS16485 +1.3 1.3 ribonuclease T compare
BWI76_RS18755 +1.2 1.9 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS05810 +1.1 1.6 hypothetical protein compare
BWI76_RS01800 +1.1 3.5 glucose-6-phosphate isomerase compare
BWI76_RS09150 +1.1 5.6 DNA-binding transcriptional repressor DeoR compare
BWI76_RS05950 +1.1 1.9 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS27915 +1.1 2.7 YceK/YidQ family lipoprotein compare
BWI76_RS02050 +1.1 2.4 CidA/LrgA family protein compare
BWI76_RS15920 +1.1 1.9 hypothetical protein compare
BWI76_RS01565 +1.1 1.7 NADH pyrophosphatase compare
BWI76_RS14755 +1.1 2.5 SIS domain-containing protein compare
BWI76_RS12815 +1.0 3.2 transcriptional regulator FeaR compare
BWI76_RS04060 +1.0 1.4 hypothetical protein compare
BWI76_RS01235 +1.0 2.0 hypothetical protein compare
BWI76_RS02180 +1.0 1.2 hypothetical protein compare
BWI76_RS14800 +1.0 2.5 non-heme chloroperoxidase compare
BWI76_RS06800 +1.0 1.4 DUF2496 domain-containing protein compare
BWI76_RS07730 +1.0 1.4 iron-enterobactin transporter membrane protein compare
BWI76_RS14835 +1.0 1.5 hypothetical protein compare
BWI76_RS06110 +1.0 3.6 hypothetical protein compare
BWI76_RS15990 +1.0 2.3 serine protease compare
BWI76_RS16910 +0.9 1.6 2-keto-4-pentenoate hydratase compare
BWI76_RS16935 +0.9 1.4 shikimate dehydrogenase compare
BWI76_RS17980 +0.9 2.2 RNA chaperone ProQ compare
BWI76_RS12680 +0.9 3.0 oxidoreductase compare
BWI76_RS11430 +0.9 1.1 lipoprotein compare
BWI76_RS11835 +0.8 1.9 putative regulatory protein MarR compare
BWI76_RS21075 +0.8 1.2 membrane protein compare
BWI76_RS10260 +0.8 2.1 creatinase compare
BWI76_RS25300 +0.8 2.4 hybrid sensor histidine kinase/response regulator compare
BWI76_RS00750 +0.8 2.5 ATP-dependent protease ATP-binding subunit HslU compare
BWI76_RS07475 +0.8 0.8 DNA-binding transcriptional regulator RamA compare
BWI76_RS25655 +0.8 1.9 DNA topoisomerase type IA zn finger domain-containing protein compare
BWI76_RS05045 +0.8 1.7 general secretion pathway protein GspM compare
BWI76_RS07820 +0.8 1.2 S-methyl-5-thioribose kinase compare
BWI76_RS24110 +0.8 1.4 YggU family protein compare
BWI76_RS13135 +0.8 1.3 3-oxoadipyl-CoA thiolase compare
BWI76_RS17675 +0.8 1.5 hypothetical protein compare
BWI76_RS11980 +0.8 1.3 DeoR family transcriptional regulator compare
BWI76_RS10040 +0.8 1.7 heat-shock protein HspQ compare
BWI76_RS17805 +0.8 1.1 membrane protein compare
BWI76_RS10755 +0.8 1.0 pyrimidine utilization flavin reductase protein F compare
BWI76_RS06665 +0.8 1.5 membrane protein compare
BWI76_RS16040 +0.8 2.0 biotin-independent malonate decarboxylase subunit gamma compare
BWI76_RS19480 +0.8 2.0 transcriptional regulator compare
BWI76_RS08825 +0.7 3.0 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS20615 +0.7 3.4 sodium symporter compare
BWI76_RS11150 +0.7 1.0 membrane protein compare
BWI76_RS03190 +0.7 1.9 hypothetical protein compare
BWI76_RS14765 +0.7 3.1 PTS lactose/cellobiose transporter subunit IIB compare
BWI76_RS19885 +0.7 2.4 multidrug ABC transporter permease/ATP-binding protein compare
BWI76_RS11970 +0.7 2.0 stress response translation initiation inhibitor YciH compare
BWI76_RS12045 +0.7 1.1 hypothetical protein compare
BWI76_RS24240 +0.7 1.4 hypothetical protein compare
BWI76_RS20900 +0.7 0.6 outer membrane protein assembly factor BamC compare
BWI76_RS07780 +0.7 1.0 hypothetical protein compare
BWI76_RS24575 +0.7 1.1 hypothetical protein compare
BWI76_RS10650 +0.7 2.6 PTS fructose-like transporter subunit EIIB compare
BWI76_RS16795 +0.7 1.6 amino acid ABC transporter ATPase compare
BWI76_RS15195 +0.7 1.4 DUF4186 domain-containing protein compare
BWI76_RS01900 +0.7 1.9 tRNA-dihydrouridine synthase A compare
BWI76_RS17565 +0.7 1.3 hypothetical protein compare
BWI76_RS17300 +0.7 1.4 tRNA-Tyr compare
BWI76_RS06290 +0.7 1.3 ACP phosphodiesterase compare
BWI76_RS11365 +0.7 1.7 iron ABC transporter compare
BWI76_RS21660 +0.7 1.1 antirestriction protein compare
BWI76_RS25925 +0.6 1.4 hypothetical protein compare
BWI76_RS02265 +0.6 1.9 putative transmembrane protein compare
BWI76_RS12795 +0.6 1.9 DedA family protein compare
BWI76_RS23050 +0.6 1.7 cobalt-precorrin-3B C(17)-methyltransferase compare
BWI76_RS16950 +0.6 1.7 TetR family transcriptional regulator compare
BWI76_RS26065 +0.6 1.9 phosphoglycolate phosphatase compare
BWI76_RS23015 +0.6 1.1 cobalt transporter ATP-binding subunit compare
BWI76_RS20475 +0.6 1.4 phospholipid-binding lipoprotein MlaA compare
BWI76_RS08275 +0.6 0.9 LexA regulated protein compare
BWI76_RS16020 +0.6 2.2 malonate decarboxylase subunit alpha compare
BWI76_RS10735 +0.6 1.4 hypothetical protein compare
BWI76_RS23030 +0.6 1.6 cobalamin biosynthesis protein CbiM compare
BWI76_RS18695 +0.6 2.1 GntR family transcriptional regulator compare
BWI76_RS12495 +0.6 1.2 2-Cys peroxiredoxin compare
BWI76_RS27770 +0.6 2.6 hypothetical protein compare
BWI76_RS02855 +0.6 1.4 cytochrome B562 compare
BWI76_RS18485 +0.6 2.6 LysR family transcriptional regulator compare
BWI76_RS26755 +0.6 3.3 peptidase M16 compare
BWI76_RS03105 +0.6 0.9 myo-inosose-2 dehydratase compare
BWI76_RS11920 +0.6 1.4 hypothetical protein compare
BWI76_RS22050 +0.6 2.4 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI compare
BWI76_RS22715 +0.6 1.6 type I-E CRISPR-associated endoribonuclease Cas2 compare
BWI76_RS17860 +0.6 1.2 YoaH family protein compare
BWI76_RS20455 +0.6 2.7 multifunctional fatty acid oxidation complex subunit alpha compare
BWI76_RS16645 +0.6 0.8 DeoR family transcriptional regulator compare
BWI76_RS18780 +0.6 1.1 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS00715 +0.6 1.6 two-component sensor histidine kinase compare
BWI76_RS10580 +0.6 2.0 amino acid ABC transporter permease compare
BWI76_RS06785 +0.6 2.1 DNA-binding transcriptional repressor AcrR compare
BWI76_RS14665 +0.6 1.6 minor fimbrial subunit YfcQ compare
BWI76_RS27620 +0.6 1.0 hypothetical protein compare
BWI76_RS24750 +0.6 2.4 membrane protein compare
BWI76_RS22835 +0.6 2.1 MFS transporter compare
BWI76_RS13605 +0.6 2.3 porin compare
BWI76_RS05050 +0.6 1.2 general secretion pathway protein GspL compare
BWI76_RS13215 +0.6 0.9 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS15015 +0.6 1.0 DUF2132 domain-containing protein compare
BWI76_RS17065 +0.6 2.7 phosphoenolpyruvate synthase compare
BWI76_RS11445 +0.6 2.4 hypothetical protein compare
BWI76_RS18615 +0.6 1.8 glutathione S-transferase domain protein compare
BWI76_RS22855 +0.6 1.4 hypothetical protein compare
BWI76_RS00080 +0.6 1.9 N-acetylmannosamine kinase compare
BWI76_RS20085 +0.6 1.2 GNAT family N-acetyltransferase compare
BWI76_RS15215 +0.6 0.7 N-acetyltransferase compare
BWI76_RS03025 +0.6 1.1 N-acetyltransferase compare
BWI76_RS19530 +0.6 1.5 YIP1 family protein compare
BWI76_RS20755 +0.6 2.3 microcompartment protein EutL compare
BWI76_RS25920 +0.6 0.6 peptidylprolyl isomerase compare
BWI76_RS17000 +0.5 1.6 Fe-S cluster assembly scaffold SufA compare
BWI76_RS01560 +0.5 2.3 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS18815 +0.5 1.2 nitrogenase molybdenum-iron protein alpha chain compare
BWI76_RS27640 +0.5 2.1 hypothetical protein compare
BWI76_RS19145 +0.5 1.1 formate dehydrogenase cytochrome b556 subunit compare
BWI76_RS23190 +0.5 1.2 propanediol utilization protein PduU compare
BWI76_RS22200 +0.5 1.9 iron ABC transporter compare
BWI76_RS10530 +0.5 1.4 GntR family transcriptional regulator with compare
BWI76_RS16760 +0.5 1.1 lipase compare
BWI76_RS00345 +0.5 1.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS09240 +0.5 1.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23675 +0.5 1.4 allulose-6-phosphate 3-epimerase compare
BWI76_RS11125 +0.5 0.9 metal-dependent hydrolase compare
BWI76_RS02625 +0.5 1.1 PTS ascorbate transporter subunit IIB compare
BWI76_RS13805 +0.5 1.1 inorganic diphosphatase compare
BWI76_RS03585 +0.5 2.0 ethanolamine utilization protein EutN compare
BWI76_RS07350 +0.5 1.4 alcohol dehydrogenase compare
BWI76_RS19615 +0.5 1.5 vancomycin high temperature exclusion protein compare
BWI76_RS15670 +0.5 2.2 hypothetical protein compare
BWI76_RS10365 +0.5 1.3 class IV aminotransferase compare
BWI76_RS21680 +0.5 2.2 antitoxin of the YeeV-YeeU toxin-antitoxin system compare
BWI76_RS10585 +0.5 1.2 amino acid ABC transporter ATP-binding protein compare
BWI76_RS02745 +0.5 0.8 hypothetical protein compare
BWI76_RS13380 +0.5 1.5 hypothetical protein compare
BWI76_RS18835 +0.5 1.9 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
BWI76_RS19695 +0.5 1.2 membrane protein compare
BWI76_RS25290 +0.5 2.2 monofunctional biosynthetic peptidoglycan transglycosylase compare
BWI76_RS12855 +0.5 1.0 enamine deaminase RidA compare
BWI76_RS20465 +0.5 1.2 hypothetical protein compare
BWI76_RS18335 +0.5 2.6 DNA-binding response regulator compare
BWI76_RS15185 +0.5 0.8 N-acetyltransferase compare
BWI76_RS07925 +0.5 1.7 hypothetical protein compare
BWI76_RS02055 +0.5 2.2 murein hydrolase effector protein LrgB compare
BWI76_RS21245 +0.5 1.8 nitrogen regulatory protein P-II compare
BWI76_RS18650 +0.5 2.0 fimbrial protein compare
BWI76_RS26365 +0.5 2.0 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS14915 +0.5 1.4 hypothetical protein compare
BWI76_RS22130 +0.5 2.1 fructose-1-phosphate/6-phosphogluconate phosphatase compare
BWI76_RS13770 +0.5 1.0 alkylhydroperoxidase domain protein compare
BWI76_RS09310 +0.5 2.1 hypothetical protein compare
BWI76_RS11690 +0.5 2.4 succinylglutamate desuccinylase compare
BWI76_RS10745 +0.5 0.6 hypothetical protein compare
BWI76_RS05465 +0.5 0.6 amidohydrolase compare
BWI76_RS06810 +0.5 1.8 hypothetical protein compare
BWI76_RS05700 +0.5 2.8 coenzyme F420-dependent NADP oxidoreductase compare
BWI76_RS07845 +0.5 0.8 LacI family transcriptional regulator compare
BWI76_RS12520 +0.5 1.4 hypothetical protein compare
BWI76_RS12745 +0.5 2.0 putative prophage membrane protein compare
BWI76_RS05480 +0.5 1.9 class II glutamine amidotransferase compare
BWI76_RS20530 +0.5 1.6 hypothetical protein compare
BWI76_RS05885 +0.5 1.5 anion permease compare
BWI76_RS17360 +0.5 3.1 nitrate reductase compare
BWI76_RS13240 +0.5 0.7 hypothetical protein compare
BWI76_RS20410 +0.5 1.7 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC compare
BWI76_RS00790 +0.5 3.0 bifunctional aspartokinase II/homoserine dehydrogenase II compare
BWI76_RS09560 +0.5 0.7 DoxX family membrane protein compare
BWI76_RS19515 +0.5 1.1 D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) (from data) compare
BWI76_RS21565 +0.5 0.7 outer membrane protein assembly factor BamE compare
BWI76_RS16805 +0.5 0.8 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS05325 +0.5 1.3 hypothetical protein compare
BWI76_RS20360 +0.5 0.6 cell division protein DedD compare
BWI76_RS21195 +0.5 2.0 3-phenylpropionic acid transporter compare
BWI76_RS09455 +0.5 1.5 YbjN domain-containing protein compare
BWI76_RS00695 +0.5 2.4 AraC family transcriptional regulator compare
BWI76_RS14615 +0.5 0.7 hypothetical protein compare
BWI76_RS12860 +0.5 0.7 hypothetical protein compare
BWI76_RS15235 +0.5 1.2 hypothetical protein compare
BWI76_RS20770 +0.5 2.3 reactivating factor for ethanolamine ammonia lyase compare
BWI76_RS10640 +0.5 1.4 AraC family transcriptional regulator compare
BWI76_RS04165 +0.5 1.6 DNA repair protein RadA compare
BWI76_RS22635 +0.5 1.5 MFS transporter compare
BWI76_RS13445 +0.5 1.0 alpha/beta hydrolase compare
BWI76_RS03825 +0.5 2.2 4-hydroxyphenylacetate 3-monooxygenase compare
BWI76_RS16355 +0.5 1.4 electron transport complex subunit A compare
BWI76_RS19340 +0.5 1.7 xylulokinase compare
BWI76_RS07995 +0.5 0.8 twin-arginine translocase subunit TatA compare
BWI76_RS22360 +0.5 2.0 hydrogenase formation protein HypD compare
BWI76_RS08745 +0.5 2.2 proline-specific permease compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source 2'-Deoxyinosine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxyinosine across organisms