Experiment set11IT075 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxycytidine 5 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18935 -7.0 -6.8 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS18930 -6.5 -3.8 histidinol-phosphate transaminase compare
BWI76_RS21475 -6.5 -6.3 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS23920 -6.3 -4.4 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS18925 -5.8 -6.9 histidinol dehydrogenase compare
BWI76_RS00990 -5.8 -6.9 ketol-acid reductoisomerase compare
BWI76_RS04470 -5.7 -9.5 carbamoyl phosphate synthase large subunit compare
BWI76_RS18940 -5.7 -3.9 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS08385 -5.6 -3.4 citrate (Si)-synthase compare
BWI76_RS04160 -5.6 -6.6 phosphoserine phosphatase compare
BWI76_RS00785 -5.4 -6.4 cystathionine gamma-synthase compare
BWI76_RS00805 -5.3 -5.8 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04135 -5.3 -7.9 thymidine phosphorylase compare
BWI76_RS00835 -5.2 -11.7 phosphoenolpyruvate carboxylase compare
BWI76_RS04250 -5.2 -6.5 homoserine kinase compare
BWI76_RS11850 -5.2 -8.6 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00855 -5.2 -7.7 argininosuccinate lyase compare
BWI76_RS05835 -5.2 -3.5 gamma-glutamyl-phosphate reductase compare
BWI76_RS04675 -5.1 -6.4 3-isopropylmalate dehydrogenase compare
BWI76_RS09755 -5.1 -9.7 phosphoserine transaminase compare
BWI76_RS23220 -5.0 -7.6 amino-acid N-acetyltransferase compare
BWI76_RS04245 -5.0 -14.1 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS09760 -5.0 -5.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS26085 -4.9 -3.2 3-dehydroquinate synthase compare
BWI76_RS23360 -4.9 -3.4 diaminopimelate decarboxylase compare
BWI76_RS18955 -4.9 -6.0 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS01655 -4.8 -6.3 homoserine O-succinyltransferase compare
BWI76_RS09645 -4.8 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS04465 -4.7 -5.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04685 -4.7 -13.1 putative leucine operon leader peptide compare
BWI76_RS04255 -4.7 -9.9 threonine synthase compare
BWI76_RS00845 -4.6 -8.0 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS18950 -4.6 -3.8 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS03010 -4.5 -9.7 ornithine carbamoyltransferase compare
BWI76_RS21265 -4.5 -15.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS11840 -4.5 -4.3 tryptophan synthase subunit alpha compare
BWI76_RS25115 -4.5 -5.7 argininosuccinate synthase compare
BWI76_RS24285 -4.5 -8.8 cystathionine beta-lyase compare
BWI76_RS05840 -4.5 -6.0 glutamate 5-kinase compare
BWI76_RS11855 -4.4 -7.2 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00965 -4.4 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS04670 -4.3 -10.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS02815 -4.3 -3.0 fructose-bisphosphatase class I compare
BWI76_RS04665 -4.2 -16.5 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00980 -4.1 -9.3 PLP-dependent threonine dehydratase compare
BWI76_RS00975 -4.1 -11.1 dihydroxy-acid dehydratase compare
BWI76_RS00850 -4.0 -8.5 acetylglutamate kinase compare
BWI76_RS26620 -4.0 -1.5 Fe-S biogenesis protein NfuA compare
BWI76_RS04130 -3.9 -5.9 2-deoxyribose-5-phosphate aldolase compare
BWI76_RS04645 -3.9 -4.8 3-dehydroquinase compare
BWI76_RS20350 -3.9 -7.0 amidophosphoribosyltransferase compare
BWI76_RS01615 -3.9 -8.5 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS01610 -3.8 -5.9 phosphoribosylamine--glycine ligase compare
BWI76_RS11860 -3.8 -7.3 anthranilate synthase component I compare
BWI76_RS07070 -3.8 -7.2 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS20895 -3.7 -7.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04680 -3.7 -8.4 2-isopropylmalate synthase compare
BWI76_RS09660 -3.6 -2.5 DNA translocase FtsK compare
BWI76_RS21465 -3.6 -3.5 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS06185 -3.6 -10.4 shikimate kinase II compare
BWI76_RS19610 -3.5 -4.1 Cytidine deaminase (EC 3.5.4.5) (from data) compare
BWI76_RS20965 -3.5 -4.6 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS18920 -3.5 -4.0 ATP phosphoribosyltransferase compare
BWI76_RS04140 -3.4 -4.2 phosphopentomutase compare
BWI76_RS07065 -3.4 -10.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS20355 -3.4 -3.2 colicin V production protein compare
BWI76_RS11845 -3.3 -3.1 tryptophan synthase subunit beta compare
BWI76_RS23480 -3.3 -13.4 EAL domain-containing protein compare
BWI76_RS23230 -3.2 -3.8 exodeoxyribonuclease V subunit beta compare
BWI76_RS01200 -3.2 -3.0 diaminopimelate epimerase compare
BWI76_RS22755 -3.2 -5.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS22765 -3.2 -11.3 sulfite reductase subunit alpha compare
BWI76_RS23365 -3.2 -8.7 LysR family transcriptional regulator compare
BWI76_RS20435 -3.1 -1.6 chorismate synthase compare
BWI76_RS04240 -3.0 -2.9 thr operon leader peptide compare
BWI76_RS15825 -2.9 -3.0 hypothetical protein compare
BWI76_RS22760 -2.9 -5.3 sulfite reductase subunit beta compare
BWI76_RS05120 -2.8 -6.9 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS23240 -2.8 -4.1 exonuclease V subunit gamma compare
BWI76_RS03080 -2.8 -3.7 (Fe-S)-cluster assembly protein compare
BWI76_RS01210 -2.7 -5.0 tyrosine recombinase XerC compare
BWI76_RS08405 -2.6 -2.7 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS20995 -2.6 -4.4 RNA degradosome polyphosphate kinase compare
BWI76_RS01185 -2.5 -1.7 adenylate cyclase compare
BWI76_RS26175 -2.4 -4.8 DeoR/GlpR family transcriptional regulator compare
BWI76_RS20170 -2.3 -4.5 NADH-quinone oxidoreductase subunit F compare
BWI76_RS04705 -2.2 -6.3 DNA-binding transcriptional regulator FruR compare
BWI76_RS00985 -2.2 -4.0 transcriptional regulator IlvY compare
BWI76_RS08395 -2.2 -2.1 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS05570 -2.1 -1.6 hypothetical protein compare
BWI76_RS22690 -2.1 -2.0 adenylyl-sulfate kinase compare
BWI76_RS21450 -2.1 -2.7 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS20160 -2.1 -3.3 NADH-quinone oxidoreductase subunit H compare
BWI76_RS20130 -2.1 -5.2 NADH-quinone oxidoreductase subunit N compare
BWI76_RS12465 -2.1 -1.3 phage shock protein D compare
BWI76_RS03595 -2.0 -1.4 ethanolamine utilization protein EutM compare
BWI76_RS20145 -2.0 -2.1 NADH-quinone oxidoreductase subunit K compare
BWI76_RS22240 -2.0 -6.4 transcriptional regulator compare
BWI76_RS01070 -2.0 -7.7 thiol reductase thioredoxin compare
BWI76_RS02410 -1.9 -1.3 EF-P beta-lysylation protein EpmB compare
BWI76_RS20190 -1.9 -6.2 NADH-quinone oxidoreductase subunit A compare
BWI76_RS06485 -1.8 -2.5 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS20180 -1.8 -4.6 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS13215 -1.7 -1.4 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS10575 -1.7 -1.5 polar amino acid ABC transporter permease compare
BWI76_RS04305 -1.7 -1.4 molecular chaperone DnaJ compare
BWI76_RS20650 -1.7 -1.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS21130 -1.7 -2.6 Fe-S assembly protein IscX compare
BWI76_RS09970 -1.7 -3.2 porin OmpA compare
BWI76_RS02610 -1.6 -4.8 transcriptional regulator compare
BWI76_RS09640 -1.6 -3.0 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS27475 -1.6 -7.0 regulatory protein GntR family protein compare
BWI76_RS09635 -1.6 -2.1 amino acid ABC transporter ATP-binding protein compare
BWI76_RS26570 -1.6 -2.8 anion permease compare
BWI76_RS05200 -1.6 -2.4 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS25245 -1.6 -2.5 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase compare
BWI76_RS02735 -1.6 -4.0 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS18455 -1.5 -1.5 tRNA-Ser compare
BWI76_RS16490 -1.5 -2.3 glutaredoxin compare
BWI76_RS14065 -1.5 -1.3 hypothetical protein compare
BWI76_RS14935 -1.5 -1.4 NIPSNAP family containing protein compare
BWI76_RS20380 -1.5 -1.3 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS25420 -1.4 -4.3 malate dehydrogenase compare
BWI76_RS11125 -1.4 -1.3 metal-dependent hydrolase compare
BWI76_RS26055 -1.4 -5.2 siroheme synthase compare
BWI76_RS20970 -1.4 -1.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS07865 -1.4 -1.8 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS16275 -1.4 -2.3 fumarate hydratase FumA compare
BWI76_RS20135 -1.4 -2.5 NADH-quinone oxidoreductase subunit M compare
BWI76_RS02095 -1.4 -5.0 acetyl-coenzyme A synthetase compare
BWI76_RS20270 -1.4 -3.5 hypothetical protein compare
BWI76_RS12330 -1.3 -2.9 hypothetical protein compare
BWI76_RS19935 -1.3 -1.5 hypothetical protein compare
BWI76_RS21370 -1.3 -1.9 ATP-dependent RNA helicase SrmB compare
BWI76_RS12055 -1.3 -3.3 DNA single-strand annealing protein RecT-like protein compare
BWI76_RS09655 -1.3 -3.2 leucine-responsive regulatory protein compare
BWI76_RS24850 -1.3 -4.9 DeoR family transcriptional regulator compare
BWI76_RS09025 -1.3 -2.0 GntR family transcriptional regulator compare
BWI76_RS14575 -1.2 -2.6 TENA/THI-4 family protein compare
BWI76_RS27440 -1.2 -2.8 DNA helicase RecG compare
BWI76_RS08230 -1.2 -2.9 hypothetical protein compare
BWI76_RS00400 -1.2 -0.7 glutamine synthetase compare
BWI76_RS24900 -1.2 -1.7 DeoR family transcriptional regulator compare
BWI76_RS21985 -1.2 -5.1 acetaldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
BWI76_RS09610 -1.2 -3.5 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS12090 -1.2 -1.0 HNH endonuclease compare
BWI76_RS06525 -1.2 -3.9 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS15830 -1.2 -2.2 hypothetical protein compare
BWI76_RS25280 -1.2 -1.7 RNase adaptor protein RapZ compare
BWI76_RS17180 -1.2 -2.0 hypothetical protein compare
BWI76_RS00440 -1.2 -1.7 CopG family transcriptional regulator compare
BWI76_RS04955 -1.2 -1.9 hypoxanthine phosphoribosyltransferase compare
BWI76_RS06495 -1.1 -4.9 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS27075 -1.1 -4.6 IclR family transcriptional regulator compare
BWI76_RS18360 -1.1 -1.5 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS09725 -1.1 -2.6 MurR/RpiR family transcriptional regulator compare
BWI76_RS13250 -1.1 -1.1 cytochrome b561 compare
BWI76_RS17400 -1.1 -1.2 transporter compare
BWI76_RS11255 -1.1 -1.6 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS08390 -1.1 -1.6 hypothetical protein compare
BWI76_RS20140 -1.1 -4.5 NADH-quinone oxidoreductase subunit L compare
BWI76_RS21990 -1.1 -6.0 ATPase AAA compare
BWI76_RS26940 -1.1 -5.0 transcriptional regulator compare
BWI76_RS21070 -1.1 -1.5 outer membrane protein assembly factor BamB compare
BWI76_RS25960 -1.1 -3.2 NUDIX hydrolase compare
BWI76_RS01100 -1.1 -3.4 dTDP-glucose 4,6-dehydratase compare
BWI76_RS06440 -1.0 -2.3 AP endonuclease compare
BWI76_RS20165 -1.0 -3.4 NADH-quinone oxidoreductase subunit G compare
BWI76_RS14075 -1.0 -1.0 TetR family transcriptional regulator compare
BWI76_RS14390 -1.0 -1.6 hypothetical protein compare
BWI76_RS15835 -1.0 -0.6 hypothetical protein compare
BWI76_RS12735 -1.0 -2.7 phage repressor protein compare
BWI76_RS01995 -1.0 -1.0 AraC family transcriptional regulator compare
BWI76_RS01125 -1.0 -3.0 4-alpha-L-fucosyltransferase compare
BWI76_RS04530 -1.0 -1.9 peptidylprolyl isomerase SurA compare
BWI76_RS00355 -1.0 -1.6 DNA polymerase I compare
BWI76_RS03415 -1.0 -2.3 LacI family transcriptional regulator compare
BWI76_RS23895 -1.0 -1.1 Xaa-Pro aminopeptidase compare
BWI76_RS05015 -1.0 -1.2 transcriptional regulator compare
BWI76_RS13895 -1.0 -1.5 LysR family transcriptional regulator compare
BWI76_RS27430 -1.0 -0.8 (p)ppGpp synthetase compare
BWI76_RS18605 -1.0 -0.8 oxidoreductase molybdopterin-binding protein compare
BWI76_RS13595 -1.0 -4.6 transcriptional regulator compare
BWI76_RS01385 -1.0 -1.9 potassium transporter compare
BWI76_RS06595 -1.0 -1.8 hypothetical protein compare
BWI76_RS01940 -1.0 -2.3 hypothetical protein compare
BWI76_RS25380 -1.0 -1.9 oxaloacetate decarboxylase subunit beta compare
BWI76_RS25355 -1.0 -3.1 cell division protein ZapE compare
BWI76_RS15775 -1.0 -1.7 replication protein compare
BWI76_RS12280 -0.9 -2.5 hypothetical protein compare
BWI76_RS04515 -0.9 -1.3 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS17195 -0.9 -1.8 hypothetical protein compare
BWI76_RS04510 -0.9 -1.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS24765 -0.9 -2.0 membrane protein compare
BWI76_RS08525 -0.9 -2.4 colicin transporter compare
BWI76_RS08380 -0.9 -1.5 endonuclease VIII compare
BWI76_RS05005 -0.9 -1.7 polynucleotide adenylyltransferase compare
BWI76_RS23810 -0.9 -2.2 bifunctional protein-disulfide isomerase/oxidoreductase DsbC compare
BWI76_RS21795 -0.9 -2.0 EAL domain-containing protein compare
BWI76_RS20910 -0.9 -2.9 glycine cleavage system transcriptional repressor compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source 2'-Deoxycytidine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxycytidine across organisms