Experiment set11IT074 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxycytidine 10 mM carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS00765 +8.5 31.9 DNA-binding transcriptional regulator CytR compare
BWI76_RS01800 +2.5 6.5 glucose-6-phosphate isomerase compare
BWI76_RS15740 +2.0 3.7 HNH endonuclease compare
BWI76_RS17975 +1.9 8.7 tail-specific protease compare
BWI76_RS15720 +1.9 4.3 prophage protein NinE compare
BWI76_RS15620 +1.8 4.3 hypothetical protein compare
BWI76_RS15535 +1.7 4.5 hypothetical protein compare
BWI76_RS15660 +1.7 2.2 hypothetical protein compare
BWI76_RS15670 +1.7 5.0 hypothetical protein compare
BWI76_RS15725 +1.7 6.0 hypothetical protein compare
BWI76_RS15715 +1.7 5.2 putative ninG protein compare
BWI76_RS16910 +1.7 3.2 2-keto-4-pentenoate hydratase compare
BWI76_RS15730 +1.6 6.0 hypothetical protein compare
BWI76_RS15600 +1.6 4.5 hypothetical protein compare
BWI76_RS15700 +1.5 4.8 hypothetical protein compare
BWI76_RS15770 +1.5 5.7 hypothetical protein compare
BWI76_RS15590 +1.5 4.9 hypothetical protein compare
BWI76_RS15815 +1.5 8.7 hypothetical protein compare
BWI76_RS15570 +1.5 4.3 phage antirepressor Ant compare
BWI76_RS15555 +1.4 8.4 hypothetical protein compare
BWI76_RS15500 +1.4 11.7 hypothetical protein compare
BWI76_RS15525 +1.4 9.2 hypothetical protein compare
BWI76_RS15665 +1.4 7.1 hypothetical protein compare
BWI76_RS01330 +1.4 4.3 twin-arginine translocase subunit TatC compare
BWI76_RS15735 +1.4 5.1 hypothetical protein compare
BWI76_RS15640 +1.4 11.2 hypothetical protein compare
BWI76_RS15515 +1.4 9.8 hypothetical protein compare
BWI76_RS19605 +1.4 2.3 CidB/LrgB family autolysis modulator compare
BWI76_RS15545 +1.4 6.9 hypothetical protein compare
BWI76_RS15520 +1.4 11.2 hypothetical protein compare
BWI76_RS15645 +1.3 6.9 gp6 compare
BWI76_RS15565 +1.3 6.1 hypothetical protein compare
BWI76_RS15630 +1.3 5.0 hypothetical protein compare
BWI76_RS14065 +1.3 2.8 hypothetical protein compare
BWI76_RS15650 +1.3 2.3 gp5 compare
BWI76_RS15575 +1.3 7.3 hypothetical protein compare
BWI76_RS15560 +1.3 7.3 hypothetical protein compare
BWI76_RS15755 +1.3 5.7 hypothetical protein compare
BWI76_RS20795 +1.3 1.7 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS15595 +1.3 6.6 hypothetical protein compare
BWI76_RS15655 +1.3 5.9 hypothetical protein compare
BWI76_RS15550 +1.3 6.7 hypothetical protein compare
BWI76_RS15695 +1.2 5.4 hypothetical protein compare
BWI76_RS15540 +1.2 6.2 hypothetical protein compare
BWI76_RS15680 +1.2 4.1 hypothetical protein compare
BWI76_RS07820 +1.2 2.1 S-methyl-5-thioribose kinase compare
BWI76_RS15690 +1.2 4.7 hypothetical protein compare
BWI76_RS15705 +1.2 3.9 putative holin protein compare
BWI76_RS15635 +1.2 4.1 hypothetical protein compare
BWI76_RS15745 +1.2 5.0 hypothetical protein compare
BWI76_RS00720 +1.2 2.8 DNA-binding response regulator compare
BWI76_RS07725 +1.2 1.6 iron-enterobactin transporter permease compare
BWI76_RS15675 +1.2 7.3 hypothetical protein compare
BWI76_RS23020 +1.2 2.4 cobalamin biosynthesis protein CbiQ compare
BWI76_RS19705 +1.1 2.8 kinase compare
BWI76_RS13025 +1.1 2.5 histidine phosphatase family protein compare
BWI76_RS09730 +1.1 2.0 pyruvate formate lyase 1-activating protein compare
BWI76_RS09255 +1.1 1.4 hypothetical protein compare
BWI76_RS24170 +1.1 6.4 nucleoside permease compare
BWI76_RS15530 +1.1 4.3 hypothetical protein compare
BWI76_RS10745 +1.0 1.4 hypothetical protein compare
BWI76_RS19375 +1.0 1.9 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS00305 +1.0 6.2 GntR family transcriptional regulator compare
BWI76_RS19700 +1.0 2.6 deoxyribonuclease IV compare
BWI76_RS07845 +1.0 1.2 LacI family transcriptional regulator compare
BWI76_RS25060 +1.0 4.4 lipoprotein NlpI compare
BWI76_RS16965 +1.0 4.2 murein lipoprotein compare
BWI76_RS02780 +1.0 7.2 translocation and assembly module TamB compare
BWI76_RS15765 +1.0 2.8 hypothetical protein compare
BWI76_RS16900 +0.9 2.0 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS15605 +0.9 2.2 hypothetical protein compare
BWI76_RS15760 +0.9 1.7 hypothetical protein compare
BWI76_RS14755 +0.9 2.0 SIS domain-containing protein compare
BWI76_RS13030 +0.9 1.0 site-specific recombinase, phage integrase family protein compare
BWI76_RS06080 +0.9 2.7 taurine dioxygenase compare
BWI76_RS26890 +0.9 1.3 hypothetical protein compare
BWI76_RS18090 +0.9 3.1 phosphoribosylglycinamide formyltransferase 2 compare
BWI76_RS19595 +0.9 2.5 hypothetical protein compare
BWI76_RS18550 +0.9 1.5 tRNA-Asn compare
BWI76_RS23305 +0.9 2.5 NADP(H)-dependent aldo-keto reductase compare
BWI76_RS15685 +0.9 2.8 hypothetical protein compare
BWI76_RS01775 +0.9 1.1 hypothetical protein compare
BWI76_RS23140 +0.9 1.2 carboxysome shell protein compare
BWI76_RS01540 +0.9 1.1 thiamine biosynthesis protein ThiS compare
BWI76_RS07185 +0.9 1.4 hypothetical protein compare
BWI76_RS16945 +0.8 3.4 4-hydroxyphenylpyruvate dioxygenase compare
BWI76_RS00240 +0.8 1.2 FMN-binding protein MioC compare
BWI76_RS01565 +0.8 1.3 NADH pyrophosphatase compare
BWI76_RS07640 +0.8 1.4 short chain dehydrogenase compare
BWI76_RS11810 +0.8 1.5 outer membrane protein OmpW compare
BWI76_RS17565 +0.8 1.2 hypothetical protein compare
BWI76_RS12815 +0.8 2.6 transcriptional regulator FeaR compare
BWI76_RS00865 +0.8 2.6 DNA-binding transcriptional regulator OxyR compare
BWI76_RS06120 +0.8 1.2 membrane protein compare
BWI76_RS15505 +0.8 5.0 hypothetical protein compare
BWI76_RS05700 +0.8 2.6 coenzyme F420-dependent NADP oxidoreductase compare
BWI76_RS25220 +0.8 1.7 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS09240 +0.8 1.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS18335 +0.8 4.4 DNA-binding response regulator compare
BWI76_RS21375 +0.8 1.0 autonomous glycyl radical cofactor GrcA compare
BWI76_RS21390 +0.8 1.9 thiol disulfide reductase thioredoxin compare
BWI76_RS18125 +0.8 1.7 murein DD-endopeptidase MepM compare
BWI76_RS06785 +0.8 4.0 DNA-binding transcriptional repressor AcrR compare
BWI76_RS15990 +0.8 1.4 serine protease compare
BWI76_RS17860 +0.7 1.5 YoaH family protein compare
BWI76_RS16690 +0.7 2.5 peptide ABC transporter permease compare
BWI76_RS09520 +0.7 1.4 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS07385 +0.7 1.9 short-chain dehydrogenase/reductase SDR compare
BWI76_RS16485 +0.7 0.7 ribonuclease T compare
BWI76_RS21920 +0.7 1.8 amino acid ABC transporter substrate-binding protein compare
BWI76_RS09860 +0.7 2.2 hypothetical protein compare
BWI76_RS10055 +0.7 1.8 AraC family transcriptional regulator compare
BWI76_RS16755 +0.7 1.7 acetoin reductase compare
BWI76_RS07345 +0.7 2.9 family 3 extracellular solute-binding protein compare
BWI76_RS16445 +0.7 3.0 auxiliary transporter membrane fusion protein compare
BWI76_RS23015 +0.7 1.2 cobalt transporter ATP-binding subunit compare
BWI76_RS27745 +0.7 1.1 PTS sugar transporter subunit IIB compare
BWI76_RS26125 +0.7 2.3 carboxypeptidase/penicillin-binding protein 1A compare
BWI76_RS06110 +0.7 3.1 hypothetical protein compare
BWI76_RS23120 +0.7 1.2 propanediol dehydratase medium subunit compare
BWI76_RS08825 +0.7 1.5 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS00795 +0.7 1.2 carboxymuconolactone decarboxylase compare
BWI76_RS24575 +0.7 1.2 hypothetical protein compare
BWI76_RS02050 +0.7 1.1 CidA/LrgA family protein compare
BWI76_RS11780 +0.7 1.8 2-deoxyglucose-6-phosphatase compare
BWI76_RS20040 +0.7 2.4 tricarboxylic transport membrane protein compare
BWI76_RS16795 +0.7 1.6 amino acid ABC transporter ATPase compare
BWI76_RS17190 +0.7 1.3 TonB system transport protein TonB compare
BWI76_RS13130 +0.6 1.5 phenylacetic acid degradation protein PaaD compare
BWI76_RS14765 +0.6 2.4 PTS lactose/cellobiose transporter subunit IIB compare
BWI76_RS21190 +0.6 3.9 stationary phase inducible protein CsiE compare
BWI76_RS14665 +0.6 2.1 minor fimbrial subunit YfcQ compare
BWI76_RS21165 +0.6 1.2 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS14320 +0.6 1.3 hypothetical protein compare
BWI76_RS06910 +0.6 1.0 transcriptional regulator compare
BWI76_RS23370 +0.6 2.0 aspartate/glutamate racemase compare
BWI76_RS27425 +0.6 1.8 DNA-directed RNA polymerase subunit omega compare
BWI76_RS06290 +0.6 1.2 ACP phosphodiesterase compare
BWI76_RS22475 +0.6 1.6 heme ABC transporter ATP-binding protein compare
BWI76_RS09850 +0.6 3.8 L,D-transpeptidase compare
BWI76_RS24920 +0.6 1.9 YraN family protein compare
BWI76_RS10755 +0.6 0.8 pyrimidine utilization flavin reductase protein F compare
BWI76_RS26405 +0.6 0.7 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS26270 +0.6 2.2 N-acetyltransferase compare
BWI76_RS14005 +0.6 1.1 TetR family transcriptional regulator compare
BWI76_RS15130 +0.6 1.8 hypothetical protein compare
BWI76_RS19590 +0.6 2.1 MFS transporter compare
BWI76_RS19390 +0.6 2.0 LysR family transcriptional regulator compare
BWI76_RS05975 +0.6 2.0 ABC transporter ATP-binding protein compare
BWI76_RS03665 +0.6 1.3 ABC transporter ATP-binding protein compare
BWI76_RS14055 +0.6 1.7 LacI family transcriptional regulator compare
BWI76_RS21245 +0.6 2.2 nitrogen regulatory protein P-II compare
BWI76_RS14735 +0.6 1.8 type 11 methyltransferase compare
BWI76_RS00375 +0.6 1.9 hypothetical protein compare
BWI76_RS07970 +0.6 2.3 hypothetical protein compare
BWI76_RS26470 +0.6 2.0 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS27865 +0.6 1.5 hypothetical protein compare
BWI76_RS27175 +0.6 1.9 hypothetical protein compare
BWI76_RS13325 +0.6 2.2 dicarboxylate transporter/tellurite-resistance protein TehA compare
BWI76_RS25635 +0.6 1.4 gamma carbonic anhydrase family protein compare
BWI76_RS15305 +0.6 2.5 O-acetylserine/cysteine exporter compare
BWI76_RS11515 +0.6 0.9 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS02745 +0.6 0.9 hypothetical protein compare
BWI76_RS19530 +0.6 2.5 YIP1 family protein compare
BWI76_RS12045 +0.6 0.8 hypothetical protein compare
BWI76_RS03700 +0.6 2.1 hypothetical protein compare
BWI76_RS02580 +0.6 0.8 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS27620 +0.6 1.6 hypothetical protein compare
BWI76_RS22815 +0.6 4.0 hybrid sensor histidine kinase/response regulator compare
BWI76_RS10415 +0.6 2.7 endoribonuclease L-PSP compare
BWI76_RS20000 +0.6 2.4 competence/damage-inducible protein A compare
BWI76_RS12800 +0.6 2.6 hypothetical protein compare
BWI76_RS20695 +0.6 1.4 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS07260 +0.6 2.4 branched chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS00745 +0.6 2.1 1,4-dihydroxy-2-naphthoate polyprenyltransferase compare
BWI76_RS11920 +0.6 1.3 hypothetical protein compare
BWI76_RS24470 +0.6 2.9 hypothetical protein compare
BWI76_RS08970 +0.6 1.2 glutamine ABC transporter permease GlnP compare
BWI76_RS03825 +0.6 1.8 4-hydroxyphenylacetate 3-monooxygenase compare
BWI76_RS00380 +0.6 3.7 oxygen-independent coproporphyrinogen III oxidase compare
BWI76_RS02320 +0.6 1.2 divalent ion tolerance protein CutA compare
BWI76_RS23515 +0.6 1.4 antibiotic biosynthesis monooxygenase compare
BWI76_RS12700 +0.6 1.1 hypothetical protein compare
BWI76_RS14470 +0.6 1.9 L-serine ammonia-lyase compare
BWI76_RS16315 +0.6 1.0 SirA-like protein compare
BWI76_RS23675 +0.6 2.3 allulose-6-phosphate 3-epimerase compare
BWI76_RS02680 +0.5 1.0 EamA family transporter compare
BWI76_RS07025 +0.5 2.6 glycerate kinase II compare
BWI76_RS09515 +0.5 1.2 arginine ABC transporter substrate-binding protein compare
BWI76_RS24825 +0.5 0.9 2-hydroxy-3-oxopropionate reductase compare
BWI76_RS22260 +0.5 2.5 anaerobic nitric oxide reductase flavorubredoxin compare
BWI76_RS06635 +0.5 1.7 methylated-DNA--protein-cysteine methyltransferase compare
BWI76_RS02200 +0.5 2.3 phosphonate C-P lyase system protein PhnL compare
BWI76_RS11150 +0.5 1.0 membrane protein compare
BWI76_RS02690 +0.5 1.3 hypothetical protein compare
BWI76_RS22435 +0.5 2.7 iron ABC transporter permease AfeC compare
BWI76_RS17200 +0.5 0.9 hypothetical protein compare
BWI76_RS01855 +0.5 1.4 chorismate lyase compare
BWI76_RS19515 +0.5 1.6 D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) (from data) compare
BWI76_RS18535 +0.5 2.6 alpha/beta hydrolase compare


Specific Phenotypes

For 23 genes in this experiment

For carbon source 2'-Deoxycytidine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxycytidine across organisms