Experiment set11IT068 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxyinosine 5 mM carbon source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS17975 +2.6 9.9 tail-specific protease compare
BWI76_RS25060 +2.5 10.5 lipoprotein NlpI compare
BWI76_RS25065 +2.2 6.1 polyribonucleotide nucleotidyltransferase compare
BWI76_RS12170 +1.8 2.0 hypothetical protein compare
BWI76_RS25225 +1.8 2.5 ABC transporter permease compare
BWI76_RS05465 +1.6 2.1 amidohydrolase compare
BWI76_RS11820 +1.5 2.0 short-chain dehydrogenase/reductase SDR compare
BWI76_RS17980 +1.5 6.0 RNA chaperone ProQ compare
BWI76_RS16910 +1.4 3.2 2-keto-4-pentenoate hydratase compare
BWI76_RS15990 +1.4 4.0 serine protease compare
BWI76_RS13215 +1.4 2.2 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS16485 +1.3 1.2 ribonuclease T compare
BWI76_RS15660 +1.2 1.4 hypothetical protein compare
BWI76_RS19325 +1.2 1.4 mandelate racemase compare
BWI76_RS11365 +1.2 2.4 iron ABC transporter compare
BWI76_RS17675 +1.2 2.6 hypothetical protein compare
BWI76_RS10755 +1.2 1.5 pyrimidine utilization flavin reductase protein F compare
BWI76_RS07595 +1.2 2.8 putative oxidoreductase compare
BWI76_RS03610 +1.2 3.8 hypothetical protein compare
BWI76_RS25070 +1.1 1.9 hypothetical protein compare
BWI76_RS26065 +1.1 2.8 phosphoglycolate phosphatase compare
BWI76_RS08640 +1.1 2.3 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS20785 +1.1 1.6 ethanolamine utilization protein EutJ compare
BWI76_RS15740 +1.1 1.4 HNH endonuclease compare
BWI76_RS11435 +1.1 2.0 hypothetical protein compare
BWI76_RS07475 +1.1 1.0 DNA-binding transcriptional regulator RamA compare
BWI76_RS12550 +1.1 1.9 hypothetical protein compare
BWI76_RS06290 +1.1 2.1 ACP phosphodiesterase compare
BWI76_RS03825 +1.1 2.4 4-hydroxyphenylacetate 3-monooxygenase compare
BWI76_RS09150 +1.1 3.8 DNA-binding transcriptional repressor DeoR compare
BWI76_RS14005 +1.0 1.8 TetR family transcriptional regulator compare
BWI76_RS23050 +1.0 2.5 cobalt-precorrin-3B C(17)-methyltransferase compare
BWI76_RS11810 +1.0 2.1 outer membrane protein OmpW compare
BWI76_RS09730 +1.0 1.2 pyruvate formate lyase 1-activating protein compare
BWI76_RS09615 +1.0 1.6 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS19495 +1.0 1.4 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS01235 +1.0 1.7 hypothetical protein compare
BWI76_RS12815 +0.9 2.5 transcriptional regulator FeaR compare
BWI76_RS08275 +0.9 0.6 LexA regulated protein compare
BWI76_RS07780 +0.9 1.3 hypothetical protein compare
BWI76_RS23885 +0.9 0.9 2-octaprenylphenol hydroxylase compare
BWI76_RS14800 +0.9 4.1 non-heme chloroperoxidase compare
BWI76_RS13995 +0.9 2.7 penicillin-binding protein 2 compare
BWI76_RS21375 +0.9 1.5 autonomous glycyl radical cofactor GrcA compare
BWI76_RS18780 +0.9 1.9 D-alanyl-D-alanine carboxypeptidase compare
BWI76_RS14615 +0.9 1.3 hypothetical protein compare
BWI76_RS19405 +0.9 3.2 LysR family transcriptional regulator compare
BWI76_RS15940 +0.9 2.1 DMSO reductase maturation protein DsmD compare
BWI76_RS26410 +0.9 1.9 membrane protein compare
BWI76_RS23705 +0.9 2.9 2-deoxy-D-ribonyl-CoA 3-dehydrogenase (from data) compare
BWI76_RS08210 +0.9 1.2 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS01935 +0.9 1.8 thiamin phosphate synthase compare
BWI76_RS18830 +0.8 2.4 protein NifY compare
BWI76_RS16805 +0.8 1.4 basic amino acid ABC transporter substrate-binding protein compare
BWI76_RS24955 +0.8 2.0 hypothetical protein compare
BWI76_RS13205 +0.8 3.3 hypothetical protein compare
BWI76_RS11900 +0.8 1.3 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS03170 +0.8 1.6 hypothetical protein compare
BWI76_RS13015 +0.8 3.7 LysR family transcriptional regulator compare
BWI76_RS06110 +0.8 3.3 hypothetical protein compare
BWI76_RS21235 +0.8 1.0 hypothetical protein compare
BWI76_RS16355 +0.8 1.6 electron transport complex subunit A compare
BWI76_RS00765 +0.8 2.3 DNA-binding transcriptional regulator CytR compare
BWI76_RS20730 +0.8 1.5 hypothetical protein compare
BWI76_RS09440 +0.8 2.0 hypothetical protein compare
BWI76_RS20360 +0.8 0.9 cell division protein DedD compare
BWI76_RS16260 +0.8 1.4 two-component sensor histidine kinase compare
BWI76_RS24150 +0.8 3.2 tRNA (guanosine(46)-N7)-methyltransferase TrmB compare
BWI76_RS13775 +0.8 1.1 putative FMN-dependent luciferase-like monooxygenase compare
BWI76_RS16950 +0.8 1.3 TetR family transcriptional regulator compare
BWI76_RS16965 +0.8 3.0 murein lipoprotein compare
BWI76_RS03595 +0.8 1.2 ethanolamine utilization protein EutM compare
BWI76_RS10680 +0.8 2.1 tartrate dehydrogenase compare
BWI76_RS04655 +0.8 2.2 shikimate dehydrogenase compare
BWI76_RS11515 +0.8 1.1 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS11110 +0.8 1.9 cell division protein YceG compare
BWI76_RS09080 +0.8 1.1 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS13585 +0.8 2.2 4-oxalocrotonate tautomerase compare
BWI76_RS06785 +0.8 3.1 DNA-binding transcriptional repressor AcrR compare
BWI76_RS15195 +0.7 1.1 DUF4186 domain-containing protein compare
BWI76_RS18575 +0.7 1.1 transcriptional regulator compare
BWI76_RS13020 +0.7 3.7 NmrA family protein compare
BWI76_RS25220 +0.7 1.3 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS25290 +0.7 2.2 monofunctional biosynthetic peptidoglycan transglycosylase compare
BWI76_RS12595 +0.7 1.9 hypothetical protein compare
BWI76_RS23005 +0.7 2.0 bifunctional adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS10060 +0.7 1.1 acylphosphatase compare
BWI76_RS06665 +0.7 1.9 membrane protein compare
BWI76_RS00745 +0.7 2.2 1,4-dihydroxy-2-naphthoate polyprenyltransferase compare
BWI76_RS04360 +0.7 2.2 ribonucleoside hydrolase RihC compare
BWI76_RS13515 +0.7 2.8 amino acid permease compare
BWI76_RS04155 +0.7 2.0 membrane protein compare
BWI76_RS09035 +0.7 1.8 protein tyrosine/serine phosphatase compare
BWI76_RS19840 +0.7 0.8 hypothetical protein compare
BWI76_RS16395 +0.7 2.0 glutathione S-transferase compare
BWI76_RS16470 +0.7 1.1 transcriptional repressor NemR compare
BWI76_RS27175 +0.7 2.2 hypothetical protein compare
BWI76_RS11380 +0.7 2.1 iron-dicitrate transporter substrate-binding subunit compare
BWI76_RS07185 +0.7 1.1 hypothetical protein compare
BWI76_RS07875 +0.7 1.9 dihydrofolate reductase compare
BWI76_RS26280 +0.7 1.6 hypothetical protein compare
BWI76_RS13290 +0.7 1.9 protocatechuate 3,4-dioxygenase subunit beta compare
BWI76_RS23670 +0.7 2.2 alkaline phosphatase compare
BWI76_RS15785 +0.7 2.8 replication protein compare
BWI76_RS10735 +0.7 1.4 hypothetical protein compare
BWI76_RS25205 +0.7 1.6 hypothetical protein compare
BWI76_RS25980 +0.7 1.3 hypothetical protein compare
BWI76_RS23020 +0.7 1.4 cobalamin biosynthesis protein CbiQ compare
BWI76_RS25905 +0.7 2.0 hypothetical protein compare
BWI76_RS18235 +0.7 2.5 trehalose-phosphatase compare
BWI76_RS11235 +0.7 1.0 hypothetical protein compare
BWI76_RS06565 +0.7 3.0 putative periplasmic solute-binding protein compare
BWI76_RS12485 +0.7 1.9 TyrR family transcriptional regulator compare
BWI76_RS17565 +0.7 1.0 hypothetical protein compare
BWI76_RS06405 +0.7 1.8 2-dehydropantoate 2-reductase compare
BWI76_RS14875 +0.7 3.0 ribokinase-like domain-containing protein compare
BWI76_RS06335 +0.7 1.5 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS20085 +0.7 1.6 GNAT family N-acetyltransferase compare
BWI76_RS13030 +0.7 1.0 site-specific recombinase, phage integrase family protein compare
BWI76_RS07740 +0.7 0.7 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS09850 +0.7 3.9 L,D-transpeptidase compare
BWI76_RS13045 +0.7 2.0 hypothetical protein compare
BWI76_RS12745 +0.7 1.6 putative prophage membrane protein compare
BWI76_RS08970 +0.7 1.3 glutamine ABC transporter permease GlnP compare
BWI76_RS16250 +0.7 2.3 DNA-binding response regulator compare
BWI76_RS18535 +0.7 2.1 alpha/beta hydrolase compare
BWI76_RS05015 +0.7 1.2 transcriptional regulator compare
BWI76_RS22130 +0.7 2.0 fructose-1-phosphate/6-phosphogluconate phosphatase compare
BWI76_RS16900 +0.7 0.8 4-hydroxy-2-oxovalerate aldolase compare
BWI76_RS12950 +0.6 2.7 acriflavin resistance protein AcrA compare
BWI76_RS11395 +0.6 1.4 RNA polymerase sigma factor FecI compare
BWI76_RS09830 +0.6 1.3 tRNA uridine 5-oxyacetic acid(34) methyltransferase CmoM compare
BWI76_RS24370 +0.6 2.2 hypothetical protein compare
BWI76_RS09520 +0.6 1.6 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS16240 +0.6 2.2 anti-adapter protein IraM compare
BWI76_RS09220 +0.6 2.7 hypothetical protein compare
BWI76_RS13880 +0.6 2.5 lysine transporter LysE compare
BWI76_RS16820 +0.6 2.4 iron ABC transporter compare
BWI76_RS16690 +0.6 2.6 peptide ABC transporter permease compare
BWI76_RS14460 +0.6 1.4 MurR/RpiR family transcriptional regulator compare
BWI76_RS22000 +0.6 3.4 hypothetical protein compare
BWI76_RS21370 +0.6 1.1 ATP-dependent RNA helicase SrmB compare
BWI76_RS20390 +0.6 1.1 erythronate-4-phosphate dehydrogenase compare
BWI76_RS16090 +0.6 1.5 two-component system response regulator DcuR compare
BWI76_RS07820 +0.6 0.9 S-methyl-5-thioribose kinase compare
BWI76_RS18770 +0.6 0.8 DNA gyrase inhibitor compare
BWI76_RS23555 +0.6 1.3 type 1 major fimbrial subunit precursor compare
BWI76_RS12445 +0.6 2.5 phage shock protein operon transcriptional activator compare
BWI76_RS10650 +0.6 1.5 PTS fructose-like transporter subunit EIIB compare
BWI76_RS10955 +0.6 0.9 hypothetical protein compare
BWI76_RS20735 +0.6 1.5 N-acetylmuramoyl-L-alanine amidase compare
BWI76_RS05450 +0.6 1.1 ribonuclease HI compare
BWI76_RS09330 +0.6 0.7 baseplate assembly protein V compare
BWI76_RS05955 +0.6 1.7 ABC transporter compare
BWI76_RS20230 +0.6 1.0 hypothetical protein compare
BWI76_RS14755 +0.6 1.4 SIS domain-containing protein compare
BWI76_RS20385 +0.6 2.4 aspartate-semialdehyde dehydrogenase compare
BWI76_RS05070 +0.6 1.5 type II secretion system protein GspH compare
BWI76_RS08220 +0.6 3.2 PTS N-acetyl glucosamine transporter subunit IIABC compare
BWI76_RS01560 +0.6 2.2 Rsd/AlgQ family anti-sigma factor compare
BWI76_RS03800 +0.6 2.0 hypothetical protein compare
BWI76_RS00865 +0.6 2.1 DNA-binding transcriptional regulator OxyR compare
BWI76_RS10035 +0.6 0.9 hypothetical protein compare
BWI76_RS19770 +0.6 1.0 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS02200 +0.6 1.6 phosphonate C-P lyase system protein PhnL compare
BWI76_RS24650 +0.6 1.4 putative transport system permease component compare
BWI76_RS26790 +0.6 3.6 cell division protein compare
BWI76_RS20310 +0.6 2.4 hypothetical protein compare
BWI76_RS05635 +0.6 2.5 AraC family transcriptional regulator compare
BWI76_RS18175 +0.6 1.4 hydrolase compare
BWI76_RS22840 +0.6 1.1 transposase compare
BWI76_RS09765 +0.6 1.6 metalloprotease compare
BWI76_RS02885 +0.6 2.3 dihydroorotase compare
BWI76_RS13875 +0.6 1.8 CbbBc protein compare
BWI76_RS19375 +0.6 0.7 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS20250 +0.6 1.8 hypothetical protein compare
BWI76_RS16795 +0.6 1.3 amino acid ABC transporter ATPase compare
BWI76_RS01600 +0.6 2.3 sensor protein ZraS compare
BWI76_RS02720 +0.6 1.9 NAD(P)-dependent oxidoreductase compare
BWI76_RS17970 +0.6 0.7 zinc metalloprotease HtpX compare
BWI76_RS06060 +0.6 2.6 DNA-binding response regulator compare
BWI76_RS00280 +0.6 1.7 ribose ABC transporter permease compare
BWI76_RS16020 +0.6 2.4 malonate decarboxylase subunit alpha compare
BWI76_RS13605 +0.6 1.9 porin compare
BWI76_RS07640 +0.6 0.9 short chain dehydrogenase compare
BWI76_RS25365 +0.6 2.7 serine endoprotease DegQ compare
BWI76_RS14725 +0.6 2.2 HxlR family transcriptional regulator compare
BWI76_RS03070 +0.6 3.6 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) (from data) compare
BWI76_RS11125 +0.6 0.9 metal-dependent hydrolase compare
BWI76_RS15125 +0.6 1.5 acetyltransferase compare
BWI76_RS11460 +0.6 1.8 DUF441 family protein compare
BWI76_RS09270 +0.6 2.5 capsid scaffold-like protein compare
BWI76_RS09160 +0.6 2.1 multidrug transporter MdfA compare
BWI76_RS05950 +0.6 0.8 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS10770 +0.6 1.7 pyrimidine utilization protein C compare
BWI76_RS08625 +0.6 1.5 UDP-glucose 4-epimerase GalE compare
BWI76_RS15210 +0.6 1.5 LysR family transcriptional regulator compare
BWI76_RS20155 +0.6 1.3 NADH-quinone oxidoreductase subunit I compare
BWI76_RS09625 +0.6 0.8 hypothetical protein compare
BWI76_RS23970 +0.6 1.3 mechanosensitive ion channel protein MscS compare


Specific Phenotypes

For 1 genes in this experiment

For carbon source 2'-Deoxyinosine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxyinosine across organisms