Experiment set11IT067 for Klebsiella michiganensis M5al

Compare to:

2'-Deoxyinosine 10 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18935 -8.1 -5.6 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00805 -7.5 -5.2 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS02995 -7.3 -5.1 aspartate carbamoyltransferase compare
BWI76_RS11965 -7.2 -5.0 orotidine-5'-phosphate decarboxylase compare
BWI76_RS09755 -6.9 -4.8 phosphoserine transaminase compare
BWI76_RS18925 -6.9 -4.8 histidinol dehydrogenase compare
BWI76_RS00855 -6.7 -4.6 argininosuccinate lyase compare
BWI76_RS18930 -6.7 -4.4 histidinol-phosphate transaminase compare
BWI76_RS04685 -6.7 -9.1 putative leucine operon leader peptide compare
BWI76_RS04465 -6.5 -4.5 carbamoyl-phosphate synthase small subunit compare
BWI76_RS21465 -6.4 -6.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS05840 -6.3 -4.4 glutamate 5-kinase compare
BWI76_RS04675 -6.2 -6.5 3-isopropylmalate dehydrogenase compare
BWI76_RS25115 -6.2 -7.3 argininosuccinate synthase compare
BWI76_RS04255 -6.1 -7.3 threonine synthase compare
BWI76_RS18940 -6.0 -4.1 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS08385 -5.9 -3.5 citrate (Si)-synthase compare
BWI76_RS04130 -5.8 -7.9 2-deoxyribose-5-phosphate aldolase compare
BWI76_RS09760 -5.7 -4.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS23920 -5.7 -6.7 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00990 -5.6 -7.4 ketol-acid reductoisomerase compare
BWI76_RS23220 -5.3 -7.6 amino-acid N-acetyltransferase compare
BWI76_RS04665 -5.1 -17.4 3-isopropylmalate dehydratase small subunit compare
BWI76_RS18955 -5.1 -5.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS09910 -5.1 -17.6 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS11850 -5.1 -8.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS23360 -5.1 -3.5 diaminopimelate decarboxylase compare
BWI76_RS11840 -5.0 -3.7 tryptophan synthase subunit alpha compare
BWI76_RS26085 -5.0 -3.2 3-dehydroquinate synthase compare
BWI76_RS04470 -5.0 -11.1 carbamoyl phosphate synthase large subunit compare
BWI76_RS18950 -5.0 -3.0 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS09645 -5.0 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS00980 -4.9 -11.0 PLP-dependent threonine dehydratase compare
BWI76_RS00850 -4.9 -7.1 acetylglutamate kinase compare
BWI76_RS00835 -4.8 -15.0 phosphoenolpyruvate carboxylase compare
BWI76_RS11860 -4.8 -9.4 anthranilate synthase component I compare
BWI76_RS04245 -4.6 -12.1 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04645 -4.4 -7.8 3-dehydroquinase compare
BWI76_RS00975 -4.4 -11.0 dihydroxy-acid dehydratase compare
BWI76_RS21475 -4.4 -6.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS27385 -4.3 -8.2 orotate phosphoribosyltransferase compare
BWI76_RS00965 -4.3 -1.6 acetolactate synthase 2 small subunit compare
BWI76_RS04160 -4.3 -3.3 phosphoserine phosphatase compare
BWI76_RS01655 -4.3 -8.0 homoserine O-succinyltransferase compare
BWI76_RS04510 -4.3 -3.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS04680 -4.3 -10.5 2-isopropylmalate synthase compare
BWI76_RS04250 -4.2 -5.6 homoserine kinase compare
BWI76_RS04670 -4.1 -6.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS23240 -4.1 -2.8 exonuclease V subunit gamma compare
BWI76_RS24285 -4.1 -6.2 cystathionine beta-lyase compare
BWI76_RS00985 -4.0 -8.4 transcriptional regulator IlvY compare
BWI76_RS04240 -4.0 -1.7 thr operon leader peptide compare
BWI76_RS03010 -3.9 -7.1 ornithine carbamoyltransferase compare
BWI76_RS22765 -3.9 -11.4 sulfite reductase subunit alpha compare
BWI76_RS00845 -3.9 -8.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS27390 -3.9 -6.1 ribonuclease PH compare
BWI76_RS22760 -3.7 -10.8 sulfite reductase subunit beta compare
BWI76_RS01615 -3.7 -12.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS18920 -3.7 -3.7 ATP phosphoribosyltransferase compare
BWI76_RS00785 -3.7 -6.1 cystathionine gamma-synthase compare
BWI76_RS06185 -3.6 -6.9 shikimate kinase II compare
BWI76_RS02530 -3.5 -3.3 tRNA dimethylallyltransferase compare
BWI76_RS23365 -3.4 -7.7 LysR family transcriptional regulator compare
BWI76_RS11855 -3.3 -6.6 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS20435 -3.2 -1.7 chorismate synthase compare
BWI76_RS05835 -3.1 -2.6 gamma-glutamyl-phosphate reductase compare
BWI76_RS17290 -3.1 -3.2 formyltetrahydrofolate deformylase compare
BWI76_RS02815 -2.8 -1.8 fructose-bisphosphatase class I compare
BWI76_RS01210 -2.8 -2.8 tyrosine recombinase XerC compare
BWI76_RS22755 -2.8 -6.4 phosphoadenosine phosphosulfate reductase compare
BWI76_RS02735 -2.8 -3.9 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS11845 -2.7 -4.1 tryptophan synthase subunit beta compare
BWI76_RS26570 -2.6 -3.8 anion permease compare
BWI76_RS05015 -2.6 -3.3 transcriptional regulator compare
BWI76_RS23230 -2.6 -5.1 exodeoxyribonuclease V subunit beta compare
BWI76_RS23480 -2.4 -10.5 EAL domain-containing protein compare
BWI76_RS04145 -2.4 -3.2 purine-nucleoside phosphorylase compare
BWI76_RS04140 -2.3 -2.5 phosphopentomutase compare
BWI76_RS08525 -2.2 -4.0 colicin transporter compare
BWI76_RS08275 -2.1 -1.8 LexA regulated protein compare
BWI76_RS26055 -2.1 -6.1 siroheme synthase compare
BWI76_RS10990 -2.1 -1.5 dihydroorotase compare
BWI76_RS18165 -2.0 -1.7 NUDIX pyrophosphatase compare
BWI76_RS04705 -2.0 -6.1 DNA-binding transcriptional regulator FruR compare
BWI76_RS16520 -2.0 -2.9 Bcr/CflA family multidrug efflux MFS transporter compare
BWI76_RS05200 -2.0 -3.1 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS22690 -1.9 -2.8 adenylyl-sulfate kinase compare
BWI76_RS24170 -1.9 -7.1 nucleoside permease compare
BWI76_RS12090 -1.9 -3.0 HNH endonuclease compare
BWI76_RS27455 -1.9 -2.9 DUF805 domain-containing protein compare
BWI76_RS04135 -1.9 -3.5 thymidine phosphorylase compare
BWI76_RS09635 -1.9 -1.3 amino acid ABC transporter ATP-binding protein compare
BWI76_RS05450 -1.8 -1.9 ribonuclease HI compare
BWI76_RS01200 -1.8 -2.4 diaminopimelate epimerase compare
BWI76_RS00065 -1.7 -5.4 MurR/RpiR family transcriptional regulator compare
BWI76_RS17300 -1.7 -2.0 tRNA-Tyr compare
BWI76_RS15835 -1.6 -1.0 hypothetical protein compare
BWI76_RS16315 -1.6 -1.8 SirA-like protein compare
BWI76_RS15825 -1.6 -2.7 hypothetical protein compare
BWI76_RS27170 -1.6 -4.3 MltR family transcriptional regulator compare
BWI76_RS20375 -1.6 -2.2 membrane protein compare
BWI76_RS01185 -1.5 -2.1 adenylate cyclase compare
BWI76_RS04955 -1.5 -2.3 hypoxanthine phosphoribosyltransferase compare
BWI76_RS27875 -1.5 -1.2 membrane protein compare
BWI76_RS26000 -1.5 -4.5 aspartate aminotransferase family protein compare
BWI76_RS06800 -1.5 -1.2 DUF2496 domain-containing protein compare
BWI76_RS10950 -1.4 -1.2 MFS transporter compare
BWI76_RS04530 -1.4 -2.6 peptidylprolyl isomerase SurA compare
BWI76_RS27475 -1.4 -7.9 regulatory protein GntR family protein compare
BWI76_RS14970 -1.4 -2.0 pyrroline-5-carboxylate reductase compare
BWI76_RS08535 -1.3 -1.6 translocation protein TolB compare
BWI76_RS21100 -1.3 -2.8 nucleoside-diphosphate kinase compare
BWI76_RS09640 -1.3 -3.0 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS16275 -1.3 -2.1 fumarate hydratase FumA compare
BWI76_RS09660 -1.3 -1.6 DNA translocase FtsK compare
BWI76_RS09655 -1.3 -2.8 leucine-responsive regulatory protein compare
BWI76_RS19330 -1.3 -1.3 HAD family hydrolase compare
BWI76_RS15845 -1.3 -1.1 hypothetical protein compare
BWI76_RS06730 -1.3 -3.1 lac repressor compare
BWI76_RS25320 -1.3 -3.9 glutamate synthase compare
BWI76_RS22620 -1.3 -3.3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase compare
BWI76_RS25315 -1.3 -6.5 glutamate synthase large subunit compare
BWI76_RS15760 -1.3 -1.4 hypothetical protein compare
BWI76_RS15830 -1.3 -2.5 hypothetical protein compare
BWI76_RS23265 -1.3 -2.1 hypothetical protein compare
BWI76_RS01885 -1.2 -1.1 CsbD family protein compare
BWI76_RS20650 -1.2 -1.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS01350 -1.2 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS16515 -1.2 -1.2 LysR family transcriptional regulator compare
BWI76_RS02985 -1.2 -3.9 reactive intermediate/imine deaminase compare
BWI76_RS03415 -1.2 -5.4 LacI family transcriptional regulator compare
BWI76_RS00710 -1.2 -1.9 6-N-hydroxylaminopurine resistance protein compare
BWI76_RS21070 -1.2 -1.1 outer membrane protein assembly factor BamB compare
BWI76_RS00795 -1.2 -1.7 carboxymuconolactone decarboxylase compare
BWI76_RS20440 -1.2 -2.1 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS25960 -1.2 -2.9 NUDIX hydrolase compare
BWI76_RS16335 -1.2 -1.6 division septum protein Blr compare
BWI76_RS11255 -1.1 -2.0 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS06295 -1.1 -3.6 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS24100 -1.1 -2.8 YggS family pyridoxal phosphate enzyme compare
BWI76_RS12195 -1.1 -3.6 hypothetical protein compare
BWI76_RS17375 -1.1 -1.6 nitrate ABC transporter, permease protein compare
BWI76_RS24850 -1.1 -3.9 DeoR family transcriptional regulator compare
BWI76_RS09025 -1.1 -2.0 GntR family transcriptional regulator compare
BWI76_RS01125 -1.1 -2.7 4-alpha-L-fucosyltransferase compare
BWI76_RS16920 -1.1 -1.6 3-(2,3-dihydroxyphenyl)propionate dioxygenase compare
BWI76_RS27430 -1.1 -0.9 (p)ppGpp synthetase compare
BWI76_RS13575 -1.1 -2.6 sugar binding transcriptional regulator, LacI family protein compare
BWI76_RS07675 -1.1 -3.1 DeoR family transcriptional regulator compare
BWI76_RS03180 -1.0 -1.5 phage transcriptional regulator, AlpA compare
BWI76_RS10655 -1.0 -2.4 [formate-C-acetyltransferase]-activating enzyme compare
BWI76_RS21580 -1.0 -1.1 SsrA-binding protein compare
BWI76_RS23030 -1.0 -1.9 cobalamin biosynthesis protein CbiM compare
BWI76_RS20695 -1.0 -1.4 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS08205 -1.0 -3.9 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS21565 -1.0 -1.0 outer membrane protein assembly factor BamE compare
BWI76_RS00970 -1.0 -1.6 branched chain amino acid aminotransferase compare
BWI76_RS22240 -1.0 -4.4 transcriptional regulator compare
BWI76_RS09190 -1.0 -3.0 hypothetical protein compare
BWI76_RS14075 -1.0 -1.6 TetR family transcriptional regulator compare
BWI76_RS05680 -1.0 -3.3 LacI family transcriptional regulator compare
BWI76_RS11105 -1.0 -2.2 aminodeoxychorismate lyase compare
BWI76_RS05120 -1.0 -4.7 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS12145 -1.0 -2.1 hypothetical protein compare
BWI76_RS21140 -1.0 -1.3 molecular chaperone HscA compare
BWI76_RS06400 -1.0 -2.1 oxidative-stress-resistance chaperone compare
BWI76_RS24315 -1.0 -2.8 cell division protein FtsP compare
BWI76_RS11435 -0.9 -0.8 hypothetical protein compare
BWI76_RS25645 -0.9 -3.8 shikimate dehydrogenase compare
BWI76_RS15035 -0.9 -1.6 metal ABC transporter permease compare
BWI76_RS15810 -0.9 -3.2 hypothetical protein compare
BWI76_RS21345 -0.9 -2.2 sigma-E factor regulatory protein RseB compare
BWI76_RS12070 -0.9 -0.9 hypothetical protein compare
BWI76_RS00440 -0.9 -1.4 CopG family transcriptional regulator compare
BWI76_RS07465 -0.9 -2.0 TetR family transcriptional regulator compare
BWI76_RS14935 -0.9 -1.1 NIPSNAP family containing protein compare
BWI76_RS20910 -0.9 -4.2 glycine cleavage system transcriptional repressor compare
BWI76_RS02095 -0.9 -4.4 acetyl-coenzyme A synthetase compare
BWI76_RS20640 -0.9 -2.0 cysteine synthase A compare
BWI76_RS20325 -0.9 -1.8 histidine/lysine/arginine/ornithine ABC transporter permease HisM compare
BWI76_RS21350 -0.9 -3.3 anti-RNA polymerase sigma factor SigE compare
BWI76_RS09690 -0.9 -1.9 dimethyl sulfoxide reductase compare
BWI76_RS03080 -0.9 -1.8 (Fe-S)-cluster assembly protein compare
BWI76_RS06595 -0.9 -1.7 hypothetical protein compare
BWI76_RS24110 -0.9 -1.5 YggU family protein compare
BWI76_RS20270 -0.9 -2.0 hypothetical protein compare
BWI76_RS11525 -0.9 -1.7 HNH endonuclease compare
BWI76_RS11835 -0.9 -1.4 putative regulatory protein MarR compare
BWI76_RS18390 -0.9 -2.1 hypothetical protein compare
BWI76_RS01220 -0.9 -3.4 DNA-dependent helicase II compare
BWI76_RS12155 -0.9 -2.1 hypothetical protein compare
BWI76_RS09650 -0.9 -3.3 hypothetical protein compare
BWI76_RS10435 -0.9 -2.9 suppressor for copper-sensitivity C compare
BWI76_RS15705 -0.8 -2.3 putative holin protein compare
BWI76_RS08580 -0.8 -3.2 quinolinate synthetase compare
BWI76_RS21480 -0.8 -1.9 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS11170 -0.8 -1.0 hypothetical protein compare
BWI76_RS01385 -0.8 -1.3 potassium transporter compare
BWI76_RS15685 -0.8 -1.9 hypothetical protein compare
BWI76_RS19700 -0.8 -1.3 deoxyribonuclease IV compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source 2'-Deoxyinosine in Klebsiella michiganensis M5al

For carbon source 2'-Deoxyinosine across organisms