Experiment set11IT061 for Klebsiella michiganensis M5al

Compare to:

2-Deoxyadenosine 5-monophosphate 5 mM carbon source

200 most important genes:

  gene name fitness t score description  
BWI76_RS04675 -7.2 -5.0 3-isopropylmalate dehydrogenase compare
BWI76_RS04130 -7.1 -4.9 2-deoxyribose-5-phosphate aldolase compare
BWI76_RS21475 -7.0 -4.6 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS09755 -6.6 -4.6 phosphoserine transaminase compare
BWI76_RS20170 -6.6 -3.8 NADH-quinone oxidoreductase subunit F compare
BWI76_RS04645 -6.4 -4.4 3-dehydroquinase compare
BWI76_RS04465 -6.3 -4.1 carbamoyl-phosphate synthase small subunit compare
BWI76_RS05840 -6.1 -4.2 glutamate 5-kinase compare
BWI76_RS18935 -6.1 -6.4 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS20160 -6.1 -3.3 NADH-quinone oxidoreductase subunit H compare
BWI76_RS18920 -5.9 -3.1 ATP phosphoribosyltransferase compare
BWI76_RS25115 -5.7 -6.7 argininosuccinate synthase compare
BWI76_RS18940 -5.7 -3.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00835 -5.6 -11.2 phosphoenolpyruvate carboxylase compare
BWI76_RS21285 -5.6 -1.5 HAD family hydrolase compare
BWI76_RS08385 -5.6 -2.5 citrate (Si)-synthase compare
BWI76_RS25160 -5.5 -1.5 transcription elongation factor GreA compare
BWI76_RS18925 -5.5 -6.1 histidinol dehydrogenase compare
BWI76_RS11335 -5.5 -1.5 tautomerase compare
BWI76_RS20145 -5.5 -1.5 NADH-quinone oxidoreductase subunit K compare
BWI76_RS08395 -5.4 -1.5 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS02815 -5.4 -2.5 fructose-bisphosphatase class I compare
BWI76_RS02995 -5.4 -7.3 aspartate carbamoyltransferase compare
BWI76_RS00785 -5.2 -6.2 cystathionine gamma-synthase compare
BWI76_RS15435 -5.2 -1.4 hypothetical protein compare
BWI76_RS05835 -5.1 -2.7 gamma-glutamyl-phosphate reductase compare
BWI76_RS07675 -5.0 -4.0 DeoR family transcriptional regulator compare
BWI76_RS21450 -4.9 -2.6 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS26085 -4.8 -2.3 3-dehydroquinate synthase compare
BWI76_RS00845 -4.8 -7.2 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS23360 -4.7 -2.5 diaminopimelate decarboxylase compare
BWI76_RS23365 -4.7 -4.6 LysR family transcriptional regulator compare
BWI76_RS00855 -4.7 -8.5 argininosuccinate lyase compare
BWI76_RS04160 -4.7 -4.6 phosphoserine phosphatase compare
BWI76_RS23220 -4.6 -7.6 amino-acid N-acetyltransferase compare
BWI76_RS01995 -4.6 -1.3 AraC family transcriptional regulator compare
BWI76_RS11840 -4.5 -3.3 tryptophan synthase subunit alpha compare
BWI76_RS20380 -4.5 -1.2 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS04670 -4.5 -7.4 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04305 -4.4 -1.2 molecular chaperone DnaJ compare
BWI76_RS08405 -4.4 -2.6 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS09530 -4.4 -1.2 hypothetical protein compare
BWI76_RS18930 -4.3 -3.6 histidinol-phosphate transaminase compare
BWI76_RS04470 -4.3 -7.0 carbamoyl phosphate synthase large subunit compare
BWI76_RS07985 -4.3 -1.2 fluoride ion transporter CrcB compare
BWI76_RS23895 -4.3 -2.0 Xaa-Pro aminopeptidase compare
BWI76_RS00990 -4.2 -5.9 ketol-acid reductoisomerase compare
BWI76_RS04250 -4.2 -5.0 homoserine kinase compare
BWI76_RS04245 -4.2 -10.0 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11860 -4.2 -6.5 anthranilate synthase component I compare
BWI76_RS11845 -4.2 -1.4 tryptophan synthase subunit beta compare
BWI76_RS10990 -4.1 -1.7 dihydroorotase compare
BWI76_RS04685 -4.1 -6.2 putative leucine operon leader peptide compare
BWI76_RS24900 -4.1 -2.2 DeoR family transcriptional regulator compare
BWI76_RS04255 -4.0 -6.2 threonine synthase compare
BWI76_RS04240 -3.9 -1.4 thr operon leader peptide compare
BWI76_RS09635 -3.9 -2.0 amino acid ABC transporter ATP-binding protein compare
BWI76_RS00975 -3.9 -5.0 dihydroxy-acid dehydratase compare
BWI76_RS09640 -3.9 -3.9 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS25600 -3.9 -1.0 tRNA-Thr compare
BWI76_RS06485 -3.9 -1.4 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS11850 -3.9 -5.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS01775 -3.8 -1.0 hypothetical protein compare
BWI76_RS20190 -3.8 -3.8 NADH-quinone oxidoreductase subunit A compare
BWI76_RS09910 -3.8 -13.7 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS27385 -3.8 -5.0 orotate phosphoribosyltransferase compare
BWI76_RS00180 -3.8 -1.5 F0F1 ATP synthase subunit epsilon compare
BWI76_RS16515 -3.7 -1.4 LysR family transcriptional regulator compare
BWI76_RS01210 -3.7 -3.0 tyrosine recombinase XerC compare
BWI76_RS01200 -3.7 -2.2 diaminopimelate epimerase compare
BWI76_RS02610 -3.5 -5.7 transcriptional regulator compare
BWI76_RS24285 -3.5 -4.5 cystathionine beta-lyase compare
BWI76_RS05075 -3.4 -0.9 type II secretion system protein GspG compare
BWI76_RS20910 -3.4 -4.1 glycine cleavage system transcriptional repressor compare
BWI76_RS09615 -3.4 -1.8 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS04665 -3.3 -11.5 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00850 -3.3 -4.7 acetylglutamate kinase compare
BWI76_RS06495 -3.3 -6.6 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS22760 -3.3 -4.2 sulfite reductase subunit beta compare
BWI76_RS23920 -3.3 -4.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00025 -3.3 -0.9 hypothetical protein compare
BWI76_RS11855 -3.2 -5.0 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS18955 -3.2 -3.7 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS20180 -3.2 -3.8 NADH-quinone oxidoreductase subunit C/D compare
BWI76_RS01655 -3.2 -5.9 homoserine O-succinyltransferase compare
BWI76_RS00980 -3.2 -6.7 PLP-dependent threonine dehydratase compare
BWI76_RS11150 -3.2 -1.2 membrane protein compare
BWI76_RS22765 -3.2 -8.9 sulfite reductase subunit alpha compare
BWI76_RS20720 -3.2 -1.2 hypothetical protein compare
BWI76_RS02735 -3.1 -3.4 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS12860 -3.1 -2.3 hypothetical protein compare
BWI76_RS04705 -3.1 -6.2 DNA-binding transcriptional regulator FruR compare
BWI76_RS18165 -3.1 -1.2 NUDIX pyrophosphatase compare
BWI76_RS06475 -3.1 -1.1 protoheme IX farnesyltransferase compare
BWI76_RS20435 -3.0 -1.1 chorismate synthase compare
BWI76_RS06185 -3.0 -4.5 shikimate kinase II compare
BWI76_RS03010 -3.0 -5.7 ornithine carbamoyltransferase compare
BWI76_RS00985 -3.0 -4.4 transcriptional regulator IlvY compare
BWI76_RS22240 -2.9 -3.2 transcriptional regulator compare
BWI76_RS22755 -2.9 -4.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS20130 -2.9 -3.4 NADH-quinone oxidoreductase subunit N compare
BWI76_RS02180 -2.9 -1.1 hypothetical protein compare
BWI76_RS09660 -2.8 -2.2 DNA translocase FtsK compare
BWI76_RS21465 -2.8 -2.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS02095 -2.8 -7.0 acetyl-coenzyme A synthetase compare
BWI76_RS20135 -2.8 -2.0 NADH-quinone oxidoreductase subunit M compare
BWI76_RS00805 -2.8 -1.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS27390 -2.8 -2.9 ribonuclease PH compare
BWI76_RS26095 -2.7 -1.0 shikimate kinase compare
BWI76_RS27875 -2.7 -1.0 membrane protein compare
BWI76_RS16520 -2.7 -3.9 Bcr/CflA family multidrug efflux MFS transporter compare
BWI76_RS20995 -2.6 -2.2 RNA degradosome polyphosphate kinase compare
BWI76_RS13515 -2.6 -2.9 amino acid permease compare
BWI76_RS15950 -2.6 -1.5 dethiobiotin synthase compare
BWI76_RS20440 -2.6 -2.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS05200 -2.5 -3.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS11365 -2.5 -1.7 iron ABC transporter compare
BWI76_RS20565 -2.5 -3.1 hypothetical protein compare
BWI76_RS09760 -2.5 -2.7 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS04510 -2.5 -1.3 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS11965 -2.5 -2.4 orotidine-5'-phosphate decarboxylase compare
BWI76_RS21675 -2.5 -0.9 hypothetical protein compare
BWI76_RS18950 -2.5 -1.3 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS17100 -2.4 -2.4 glutathione peroxidase compare
BWI76_RS01615 -2.4 -4.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS17290 -2.4 -2.7 formyltetrahydrofolate deformylase compare
BWI76_RS03080 -2.3 -3.8 (Fe-S)-cluster assembly protein compare
BWI76_RS25320 -2.3 -6.0 glutamate synthase compare
BWI76_RS23240 -2.3 -3.9 exonuclease V subunit gamma compare
BWI76_RS04680 -2.3 -7.3 2-isopropylmalate synthase compare
BWI76_RS04605 -2.3 -1.2 thiamine ABC transporter ATP-binding protein compare
BWI76_RS09610 -2.3 -3.0 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS03415 -2.3 -2.5 LacI family transcriptional regulator compare
BWI76_RS16895 -2.2 -1.6 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS20165 -2.2 -2.6 NADH-quinone oxidoreductase subunit G compare
BWI76_RS09970 -2.2 -3.8 porin OmpA compare
BWI76_RS02530 -2.2 -2.4 tRNA dimethylallyltransferase compare
BWI76_RS09515 -2.2 -2.5 arginine ABC transporter substrate-binding protein compare
BWI76_RS01350 -2.1 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS24260 -2.1 -1.9 hypothetical protein compare
BWI76_RS05810 -2.1 -0.9 hypothetical protein compare
BWI76_RS22450 -2.1 -2.0 selenoprotein W-related protein compare
BWI76_RS26055 -2.1 -5.1 siroheme synthase compare
BWI76_RS20650 -2.0 -1.1 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS06525 -2.0 -3.4 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS20795 -2.0 -0.9 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS08535 -2.0 -1.7 translocation protein TolB compare
BWI76_RS19010 -1.9 -2.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS20155 -1.9 -1.7 NADH-quinone oxidoreductase subunit I compare
BWI76_RS08205 -1.9 -2.4 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS23455 -1.9 -2.5 Na(+)-translocating NADH-quinone reductase subunit E compare
BWI76_RS25870 -1.9 -1.1 elongation factor Tu compare
BWI76_RS03700 -1.9 -1.3 hypothetical protein compare
BWI76_RS00065 -1.9 -5.0 MurR/RpiR family transcriptional regulator compare
BWI76_RS08425 -1.9 -3.5 succinyl-CoA ligase subunit beta compare
BWI76_RS24605 -1.9 -6.0 dihydroxyacetone kinase subunit DhaM compare
BWI76_RS25420 -1.8 -2.6 malate dehydrogenase compare
BWI76_RS02410 -1.8 -1.2 EF-P beta-lysylation protein EpmB compare
BWI76_RS03665 -1.8 -1.1 ABC transporter ATP-binding protein compare
BWI76_RS01115 -1.8 -2.2 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS21070 -1.8 -0.9 outer membrane protein assembly factor BamB compare
BWI76_RS15225 -1.8 -2.4 DeoR family transcriptional regulator compare
BWI76_RS17665 -1.8 -2.1 proteasome-type protease compare
BWI76_RS22690 -1.7 -2.5 adenylyl-sulfate kinase compare
BWI76_RS21985 -1.7 -5.0 acetaldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
BWI76_RS21795 -1.7 -2.0 EAL domain-containing protein compare
BWI76_RS16315 -1.7 -0.9 SirA-like protein compare
BWI76_RS14980 -1.7 -1.6 hypothetical protein compare
BWI76_RS16335 -1.7 -1.4 division septum protein Blr compare
BWI76_RS23230 -1.7 -3.6 exodeoxyribonuclease V subunit beta compare
BWI76_RS16210 -1.7 -1.0 hypothetical protein compare
BWI76_RS11100 -1.7 -2.6 beta-ketoacyl-[acyl-carrier-protein] synthase II compare
BWI76_RS05260 -1.7 -1.5 chaperone compare
BWI76_RS08430 -1.7 -2.3 succinate--CoA ligase subunit alpha compare
BWI76_RS24850 -1.7 -4.0 DeoR family transcriptional regulator compare
BWI76_RS08645 -1.7 -2.0 molybdate ABC transporter substrate-binding protein compare
BWI76_RS03045 -1.7 -0.9 hypothetical protein compare
BWI76_RS14935 -1.6 -1.1 NIPSNAP family containing protein compare
BWI76_RS08975 -1.6 -2.3 amino acid ABC transporter substrate-binding protein compare
BWI76_RS20140 -1.6 -2.4 NADH-quinone oxidoreductase subunit L compare
BWI76_RS03880 -1.6 -2.6 homoprotocatechuate degradation operon regulator, HpaR compare
BWI76_RS25280 -1.6 -1.5 RNase adaptor protein RapZ compare
BWI76_RS26570 -1.6 -1.9 anion permease compare
BWI76_RS25355 -1.6 -5.1 cell division protein ZapE compare
BWI76_RS16525 -1.6 -1.8 cyclopropane-fatty-acyl-phospholipid synthase compare
BWI76_RS13715 -1.6 -3.1 2-chlorobenzoate 1 2-dioxygenase electron transfer subunit compare
BWI76_RS26440 -1.6 -0.9 hypothetical protein compare
BWI76_RS01680 -1.6 -4.6 transcriptional regulator IclR compare
BWI76_RS26190 -1.6 -2.5 glycerol-3-phosphate dehydrogenase compare
BWI76_RS01110 -1.6 -2.6 TDP-fucosamine acetyltransferase compare
BWI76_RS27795 -1.6 -4.6 two-component system sensor histidine kinase UhpB compare
BWI76_RS26245 -1.6 -1.7 transcriptional regulator compare
BWI76_RS05050 -1.6 -2.1 general secretion pathway protein GspL compare
BWI76_RS23020 -1.6 -1.4 cobalamin biosynthesis protein CbiQ compare
BWI76_RS04135 -1.6 -3.1 thymidine phosphorylase compare
BWI76_RS27800 -1.5 -3.8 DNA-binding response regulator compare
BWI76_RS04850 -1.5 -1.7 N-acetylmuramoyl-L-alanine amidase compare
BWI76_RS06335 -1.5 -1.7 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS07860 -1.5 -2.0 cytosine permease compare
BWI76_RS04145 -1.5 -1.4 purine-nucleoside phosphorylase compare


Specific Phenotypes

For 2 genes in this experiment

For carbon source 2-Deoxyadenosine 5-monophosphate in Klebsiella michiganensis M5al

For carbon source 2-Deoxyadenosine 5-monophosphate across organisms