Experiment set11IT025 for Pseudomonas syringae pv. syringae B728a

Compare to:

KB with Cyclopamine 10 mM

200 most important genes:

  gene name fitness t score description  
Psyr_0951 -4.4 -4.2 UBA/THIF-type NAD/FAD binding fold:MoeZ/MoeB compare
Psyr_4340 -4.2 -7.5 phosphomethylpyrimidine kinase, putative compare
Psyr_3008 -3.4 -8.3 Undecaprenyl-diphosphatase compare
Psyr_4686 -3.3 -6.5 8-amino-7-oxononanoate synthase compare
Psyr_1544 -3.2 -5.6 SirA-like protein compare
Psyr_4203 -3.1 -3.0 SsrA-binding protein compare
Psyr_0014 -3.0 -4.9 lipid A biosynthesis acyltransferase compare
Psyr_1613 -2.7 -5.1 septum site-determining protein MinC compare
Psyr_1663 -2.6 -3.9 phosphoribosylanthranilate isomerase compare
Psyr_4687 -2.6 -7.5 biotin synthase compare
Psyr_4740 -2.6 -7.0 thiazole-phosphate synthase compare
Psyr_0475 -2.6 -2.5 Protein of unknown function YGGT compare
Psyr_0454 -2.5 -5.7 adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme compare
Psyr_4991 -2.4 -3.3 hypothetical protein compare
Psyr_0849 -2.4 -10.5 CDP-diacylglycerol--serine O-phosphatidyltransferase compare
Psyr_4091 -2.4 -5.6 8-oxo-dGTPase compare
Psyr_4683 -2.3 -5.0 dethiobiotin synthase compare
Psyr_1373 -2.3 -3.6 Peptidoglycan-binding LysM:Peptidase M23B compare
Psyr_4341 -2.1 -5.8 thiamine-phosphate diphosphorylase compare
Psyr_4684 -2.0 -3.4 biotin synthesis protein BioC compare
Psyr_0917 -1.9 -10.2 ABC-2 compare
Psyr_0918 -1.8 -11.1 ABC transporter compare
Psyr_4822 -1.8 -4.4 Helix-turn-helix, Fis-type:Nitrogen regulation protein NR(I) compare
Psyr_0383 -1.8 -1.8 Twin-arginine translocation protein TatB compare
Psyr_0259 -1.7 -4.0 Osmolarity sensor protein envZ compare
Psyr_0549 -1.6 -2.8 Metallophosphoesterase compare
Psyr_3213 -1.6 -3.0 Propeptide, PepSY amd peptidase M4 compare
Psyr_0574 -1.6 -5.3 protease FtsH subunit HflK compare
Psyr_1907 -1.6 -3.6 GTP cyclohydrolase I compare
Psyr_4581 -1.5 -3.5 anthranilate synthase, component II compare
Psyr_2854 -1.5 -4.3 conserved hypothetical protein compare
Psyr_4627 -1.5 -2.8 dimethyladenosine transferase compare
Psyr_3581 -1.5 -5.7 ribosomal large subunit pseudouridine synthase B compare
Psyr_4464 -1.4 -1.8 lipoprotein, putative compare
Psyr_5132 -1.4 -2.6 Glucose-inhibited division protein A subfamily compare
Psyr_1748 -1.3 -4.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Psyr_0487 -1.3 -2.6 glutathione synthase compare
Psyr_2471 -1.3 -2.3 hydroxymethylglutaryl-CoA lyase compare
Psyr_2642 -1.3 -3.9 hypothetical protein compare
Psyr_5133 -1.3 -3.5 tRNA modification GTPase trmE compare
Psyr_1667 -1.2 -4.5 Colicin V production protein compare
Psyr_1930 -1.2 -3.5 hypothetical protein compare
Psyr_2184 -1.2 -2.9 Short-chain dehydrogenase/reductase SDR compare
Psyr_4407 -1.2 -2.4 phosphoribosylamine--glycine ligase compare
Psyr_0281 -1.2 -3.5 ABC transporter compare
Psyr_1885 -1.2 -2.5 hypothetical protein compare
Psyr_4089 -1.2 -4.8 PAS compare
Psyr_1505 -1.2 -3.1 Protein of unknown function DUF156 compare
Psyr_4136 -1.1 -2.4 BolA-like protein compare
Psyr_1751 -1.1 -3.8 PpiC-type peptidyl-prolyl cis-trans isomerase compare
Psyr_0826 -1.1 -5.1 glucose-6-phosphate isomerase compare
Psyr_2807 -1.1 -2.0 NinB compare
Psyr_1556 -1.1 -2.1 hypothetical protein compare
Psyr_0565 -1.1 -4.5 Protein of unknown function UPF0126 compare
Psyr_0464 -1.1 -2.5 hypothetical protein compare
Psyr_0282 -1.1 -4.4 Binding-protein-dependent transport systems inner membrane component compare
Psyr_3554 -1.1 -2.1 Carbon storage regulator compare
Psyr_3620 -1.0 -1.1 hypothetical protein compare
Psyr_0034 -1.0 -1.0 tryptophan synthase, beta chain compare
Psyr_3808 -1.0 -1.7 hypothetical protein compare
Psyr_4884 -1.0 -3.6 Rhodanese-like protein compare
Psyr_1408 -1.0 -1.8 Holliday junction endonuclease RuvC compare
Psyr_2848 -1.0 -3.7 hypothetical protein compare
Psyr_1227 -1.0 -2.6 Queuosine biosynthesis protein compare
Psyr_0550 -1.0 -3.3 Protein of unknown function UPF0227 compare
Psyr_4362 -1.0 -2.8 Rare lipoprotein A compare
Psyr_1460 -0.9 -3.2 hypothetical protein compare
Psyr_2345 -0.9 -3.0 ea59 protein compare
Psyr_3728 -0.9 -2.9 hypothetical protein compare
Psyr_4057 -0.9 -3.0 regulatory protein, LysR:LysR, substrate-binding protein compare
Psyr_2292 -0.9 -2.0 L-glutaminase compare
Psyr_3179 -0.9 -1.8 DNA translocase FtsK compare
Psyr_2980 -0.9 -2.1 UDP-glucose pyrophosphorylase compare
Psyr_4893 -0.9 -1.7 imidazole glycerol phosphate synthase subunit hisF compare
Psyr_5072 -0.9 -1.3 Cobalamin synthesis protein/P47K:Cobalamin synthesis protein/P47K compare
Psyr_3806 -0.9 -3.4 hypothetical protein compare
Psyr_4460 -0.9 -1.8 3,4-dihydroxy-2-butanone 4-phosphate synthase / GTP cyclohydrolase II compare
Psyr_1410 -0.9 -2.4 Holliday junction DNA helicase RuvB compare
Psyr_1688 -0.9 -1.8 Protein of unknown function DUF1315 compare
Psyr_2347 -0.9 -1.5 hypothetical protein compare
Psyr_0831 -0.9 -1.8 Two-component response regulator CbrB compare
Psyr_0575 -0.9 -1.9 protease FtsH subunit HflC compare
Psyr_4408 -0.9 -4.7 Response regulator receiver:ATP-binding region, ATPase-like:Histidine kinase A, N-terminal:Histidine kinase:Histidine kinase compare
Psyr_1747 -0.8 -2.6 ATP-dependent Clp protease proteolytic subunit ClpP compare
Psyr_0215 -0.8 -5.6 Exodeoxyribonuclease III xth compare
Psyr_2855 -0.8 -3.0 methionine synthase (B12-independent) compare
Psyr_3665 -0.8 -2.1 conserved hypothetical protein compare
Psyr_3952 -0.8 -2.8 conserved hypothetical protein compare
Psyr_2251 -0.8 -1.8 Phosphonate metabolism PhnG compare
Psyr_3807 -0.8 -3.1 hypothetical protein compare
Psyr_2680 -0.8 -1.7 Binding-protein-dependent transport systems inner membrane component compare
Psyr_0493 -0.8 -1.6 CheW-like protein compare
Psyr_4566 -0.8 -4.6 Peptidase M23B compare
Psyr_1934 -0.8 -3.7 conserved hypothetical protein compare
Psyr_1588 -0.8 -2.5 Putative exonuclease, RdgC compare
Psyr_2262 -0.8 -1.9 Peptidase M20:Peptidase M20 compare
Psyr_3358 -0.8 -1.9 transmembrane pair compare
Psyr_1953 -0.8 -1.1 conserved hypothetical protein compare
Psyr_5130 -0.8 -4.8 chromosome segregation ATPase compare
Psyr_RNA61 -0.8 -2.2 tRNA-Gly compare
Psyr_1404 -0.8 -4.0 Ferritin and Dps compare
Psyr_0919 -0.8 -5.2 Chromosome segregation ATPase-like protein compare
Psyr_2769 -0.8 -1.8 conserved hypothetical protein compare
Psyr_3005 -0.8 -1.5 3-oxoadipate enol-lactonase compare
Psyr_0255 -0.8 -1.5 glutamate-cysteine ligase compare
Psyr_2112 -0.8 -1.5 Protein with unknown function DUF469 compare
Psyr_1418 -0.8 -1.6 Radical SAM compare
Psyr_1931 -0.8 -3.8 hypothetical protein compare
Psyr_0579 -0.8 -5.2 RNAse R compare
Psyr_2899 -0.7 -3.4 conserved hypothetical protein compare
Psyr_4754 -0.7 -1.7 16S rRNA m(2)G-966 methyltransferase compare
Psyr_2664 -0.7 -3.4 hypothetical protein compare
Psyr_4087 -0.7 -0.7 Protein of unknown function DUF520 compare
Psyr_2501 -0.7 -1.8 Hemerythrin compare
Psyr_0571 -0.7 -2.2 tRNA isopentenyltransferase compare
Psyr_4367 -0.7 -2.8 Iojap-related protein compare
Psyr_2779 -0.7 -1.7 Phage minor tail compare
Psyr_1458 -0.7 -2.3 hypothetical protein compare
Psyr_2847 -0.7 -1.6 hypothetical protein compare
Psyr_1123 -0.7 -2.1 conserved hypothetical protein compare
Psyr_3954 -0.7 -2.9 GTP-binding protein LepA compare
Psyr_0680 -0.7 -2.2 DNA helicase/exodeoxyribonuclease V, gamma subunit compare
Psyr_3133 -0.7 -1.5 Amidohydrolase 2 compare
Psyr_0492 -0.7 -5.0 Response regulator receiver:CheW-like protein:ATP-binding region, ATPase-like:Hpt compare
Psyr_1097 -0.7 -1.3 glycine cleavage system H protein compare
Psyr_1555 -0.7 -1.8 Cobyrinic acid a,c-diamide synthase compare
Psyr_4622 -0.7 -2.4 Nucleotidyl transferase compare
Psyr_1935 -0.7 -2.6 Protein of unknown function DUF796 compare
Psyr_1357 -0.7 -2.2 RNase HII compare
Psyr_0920 -0.7 -5.8 Glycosyl transferase, group 1 compare
Psyr_2039 -0.7 -1.6 Fimbrial protein compare
Psyr_4351 -0.7 -2.1 conserved domain protein compare
Psyr_1749 -0.7 -3.6 ATP-dependent proteinase, Serine peptidase, MEROPS family S16 compare
Psyr_2346 -0.7 -2.4 conserved hypothetical protein compare
Psyr_3833 -0.7 -2.6 Plasmid stabilization system compare
Psyr_2739 -0.7 -2.6 ThiJ/PfpI compare
Psyr_4512 -0.6 -3.0 putative phage-related protein compare
Psyr_1193 -0.6 -1.8 type III helper protein HrpZ1 compare
Psyr_0528 -0.6 -1.7 Carbamoyltransferase compare
Psyr_4995 -0.6 -2.0 RHS protein compare
Psyr_4093 -0.6 -2.1 glutamate N-acetyltransferase compare
Psyr_2607 -0.6 -3.3 regulatory protein, LuxR compare
Psyr_4634 -0.6 -0.7 Polynucleotide adenylyltransferase:Metal-dependent phosphohydrolase, HD subdomain protein compare
Psyr_2823 -0.6 -0.9 hypothetical protein compare
Psyr_3240 -0.6 -2.0 CTP synthase compare
Psyr_2154 -0.6 -2.4 transcriptional regulator, LacI family compare
Psyr_1678 -0.6 -0.8 Hypothetical protein compare
Psyr_4519 -0.6 -3.2 General substrate transporter:Major facilitator superfamily compare
Psyr_3644 -0.6 -2.2 prephenate dehydrogenase compare
Psyr_4040 -0.6 -3.5 putative cytoplasmic protein compare
Psyr_0864 -0.6 -2.2 Protein of unknown function DUF393 compare
Psyr_1371 -0.6 -3.2 5'-nucleotidase / exopolyphosphatase / 3'-nucleotidase compare
Psyr_1832 -0.6 -1.7 Exonuclease compare
Psyr_2143 -0.6 -1.4 delta1-piperideine 2-carboxylate reductase compare
Psyr_1350 -0.6 -1.5 site-2 protease, Metallo peptidase, MEROPS family M50B compare
Psyr_4112 -0.6 -3.6 Protein of unknown function UPF0011 compare
Psyr_3450 -0.6 -1.8 Hpt compare
Psyr_3026 -0.6 -2.2 transcriptional regulator, TetR family compare
Psyr_0202 -0.6 -3.7 transcriptional regulator, LysR family compare
Psyr_2030 -0.6 -1.2 Calcium-binding EF-hand compare
Psyr_2462 -0.6 -2.1 Nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like:Nitrite and sulphite reductase 4Fe-4S region compare
Psyr_3084 -0.6 -2.2 Response regulator receiver:Transcriptional regulatory protein, C-terminal compare
Psyr_1379 -0.6 -1.7 Regulatory protein RecX compare
Psyr_2071 -0.6 -0.7 outer membrane lipoprotein OprI compare
Psyr_0184 -0.6 -1.4 Protein of unknown function DUF484 compare
Psyr_1140 -0.6 -1.8 Disulfide bond formation protein DsbB compare
Psyr_3287 -0.6 -1.2 DNA topoisomerase I compare
Psyr_2084 -0.6 -2.2 transcriptional regulator, GntR family compare
Psyr_4786 -0.6 -1.4 hypothetical protein compare
Psyr_4609 -0.6 -4.2 anthranilate synthase, component I compare
Psyr_5078 -0.6 -2.1 conserved hypothetical protein compare
Psyr_2641 -0.6 -1.4 hypothetical protein compare
Psyr_5135 -0.6 -1.2 Protein of unknown function DUF37 compare
Psyr_2714 -0.6 -2.6 putative transmembrane protein compare
Psyr_0444 -0.6 -0.9 Malonate decarboxylase delta subunit compare
Psyr_1372 -0.6 -1.6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psyr_4856 -0.6 -1.5 conserved hypothetical protein compare
Psyr_1212 -0.6 -1.2 type III secretion protein HrpO compare
Psyr_3036 -0.6 -2.0 transcriptional regulator, TetR family compare
Psyr_2348 -0.6 -1.2 hypothetical protein compare
Psyr_0941 -0.6 -2.6 Conserved hypothetical protein 92 compare
Psyr_3127 -0.5 -1.9 Response regulator receiver:Transcriptional regulatory protein, C-terminal compare
Psyr_2433 -0.5 -1.4 conserved hypothetical protein compare
Psyr_0923 -0.5 -2.5 hypothetical protein compare
Psyr_4979 -0.5 -2.8 hypothetical protein compare
Psyr_2095 -0.5 -2.1 Conserved TM helix compare
Psyr_3090 -0.5 -1.3 hypothetical protein compare
Psyr_3418 -0.5 -1.8 PilT protein, N-terminal compare
Psyr_1322 -0.5 -2.2 Protein of unknown function DUF72 compare
Psyr_1670 -0.5 -1.7 Short-chain dehydrogenase/reductase SDR compare
Psyr_3208 -0.5 -1.1 NADH dehydrogenase subunit M compare
Psyr_4161 -0.5 -1.2 Rod shape-determining protein MreD compare
Psyr_2569 -0.5 -2.6 monosaccharide ABC transporter substrate-binding protein, CUT2 family compare
Psyr_2590 -0.5 -1.4 Periplasmic binding protein compare
Psyr_1553 -0.5 -2.5 hypothetical protein compare
Psyr_1389 -0.5 -1.6 Protein of unknown function DUF1456 compare
Psyr_3282 -0.5 -2.0 transcriptional regulator, TetR family compare
Psyr_2592 -0.5 -1.9 transport system permease protein compare
Psyr_3164 -0.5 -3.4 Protein of unknown function UPF0005 compare
Psyr_4118 -0.5 -2.3 Glutathione S-transferase, N-terminal:Glutathione S-transferase, C-terminal compare


Specific Phenotypes

None in this experiment

For Pseudomonas syringae pv. syringae B728a in stress experiments

For stress Cyclopamine across organisms