Experiment set11IT023 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with Thallium(I) acetate 0.002 mg/ml

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3782 -7.6 -5.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3842 -5.7 -3.9 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3932 -5.5 -7.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_5177 -5.4 -9.7 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3248 -5.2 -6.0 Probable transmembrane protein compare
Pf6N2E2_4597 -5.1 -3.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_64 -5.1 -3.5 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_71 -4.9 -4.8 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3783 -4.9 -6.7 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3253 -4.7 -5.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3630 -4.7 -5.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3382 -4.6 -9.2 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3752 -4.6 -19.3 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4279 -4.5 -16.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4048 -4.5 -9.0 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4826 -4.4 -6.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_2547 -4.4 -11.3 Protein of unknown function UPF0060 conserved
Pf6N2E2_2073 -4.3 -6.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3612 -4.3 -2.9 HflK protein compare
Pf6N2E2_3841 -4.3 -2.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4564 -4.2 -10.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_77 -4.2 -4.0 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3381 -4.1 -10.2 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_3751 -4.1 -11.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3839 -4.0 -2.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4277 -4.0 -13.4 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4596 -3.9 -8.7 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4278 -3.9 -12.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3610 -3.9 -4.8 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3384 -3.8 -5.6 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_3611 -3.8 -3.5 HflC protein compare
Pf6N2E2_5175 -3.8 -5.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_66 -3.8 -8.3 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4047 -3.8 -6.2 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_302 -3.7 -6.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3252 -3.7 -7.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_4825 -3.6 -8.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_1617 -3.6 -1.3 COG2199: FOG: GGDEF domain compare
Pf6N2E2_2129 -3.6 -4.7 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_50 -3.5 -10.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_1673 -3.5 -3.1 Transcriptional regulator, TetR family compare
Pf6N2E2_3383 -3.5 -5.0 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_5176 -3.4 -3.3 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3940 -3.4 -9.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4797 -3.4 -1.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3380 -3.4 -11.3 L-lactate permease compare
Pf6N2E2_63 -3.3 -4.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4272 -3.2 -2.2 putative membrane protein compare
Pf6N2E2_2074 -3.2 -1.7 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4072 -3.2 -9.6 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_3251 -3.1 -10.6 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5150 -2.9 -6.3 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2519 -2.8 -1.0 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_4624 -2.8 -1.1 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_4394 -2.8 -4.6 Putrescine utilization regulator compare
Pf6N2E2_2277 -2.8 -3.2 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_5258 -2.8 -8.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_2465 -2.6 -4.4 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3351 -2.6 -2.5 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_5723 -2.6 -9.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_5574 -2.6 -7.7 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_3461 -2.5 -1.6 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3763 -2.5 -1.6 hypothetical protein compare
Pf6N2E2_5841 -2.4 -0.9 GlcG protein compare
Pf6N2E2_5257 -2.4 -10.1 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2088 -2.4 -2.4 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_2899 -2.3 -5.6 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_3820 -2.2 -3.6 hypothetical protein compare
Pf6N2E2_3264 -2.2 -3.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_5728 -2.2 -5.3 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2646 -2.2 -1.4 FIG00953416: hypothetical protein compare
Pf6N2E2_2574 -2.2 -2.0 Flagellar synthesis regulator FleN compare
Pf6N2E2_1083 -2.2 -2.0 hypothetical protein compare
Pf6N2E2_1239 -2.1 -7.7 Putative TEGT family carrier/transport protein compare
Pf6N2E2_3170 -2.1 -5.7 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2121 -2.1 -2.1 hypothetical protein compare
Pf6N2E2_3627 -2.1 -7.1 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) compare
Pf6N2E2_1352 -2.1 -2.6 Cation transport ATPase compare
Pf6N2E2_5666 -2.1 -9.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4988 -2.1 -4.2 Antiholin-like protein LrgA compare
Pf6N2E2_2546 -2.1 -3.1 Carbon storage regulator compare
Pf6N2E2_5188 -2.1 -2.7 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_1391 -2.1 -2.5 DNA-binding response regulator, LuxR family compare
Pf6N2E2_2510 -2.0 -1.9 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_2258 -2.0 -8.6 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_2588 -2.0 -3.0 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_1705 -2.0 -2.5 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_1128 -2.0 -1.4 Two-component response regulator compare
Pf6N2E2_4075 -2.0 -8.5 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_4989 -2.0 -4.8 LrgA-associated membrane protein LrgB compare
Pf6N2E2_5704 -1.9 -3.2 Transcriptional regulatory protein PhoP compare
Pf6N2E2_4057 -1.9 -0.7 lipoprotein, putative compare
Pf6N2E2_3183 -1.9 -2.5 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_4773 -1.9 -1.5 Coenzyme PQQ synthesis protein D compare
Pf6N2E2_4414 -1.9 -1.2 FIG00953808: hypothetical protein compare
Pf6N2E2_5178 -1.9 -2.6 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_1987 -1.8 -2.0 hypothetical protein compare
Pf6N2E2_3349 -1.8 -3.7 Polyribonucleotide nucleotidyltransferase (EC 2.7.7.8) compare
Pf6N2E2_4074 -1.8 -14.3 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_2261 -1.8 -5.3 VacJ-like lipoprotein precursor compare
Pf6N2E2_3074 -1.8 -1.7 FIG00960973: hypothetical protein compare
Pf6N2E2_288 -1.8 -1.1 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_3941 -1.8 -1.7 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_4579 -1.8 -1.2 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2586 -1.8 -2.2 Hpt domain protein compare
Pf6N2E2_2152 -1.8 -0.8 hypothetical protein compare
Pf6N2E2_760 -1.7 -9.9 Na+/H+ antiporter NhaB compare
Pf6N2E2_5536 -1.7 -1.1 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3666 -1.7 -2.9 InaA protein compare
Pf6N2E2_1656 -1.7 -1.7 hypothetical protein compare
Pf6N2E2_3033 -1.7 -1.5 hypothetical protein compare
Pf6N2E2_4584 -1.7 -1.6 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2480 -1.7 -0.8 FIG00957636: hypothetical protein compare
Pf6N2E2_2186 -1.7 -6.6 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_3770 -1.7 -1.1 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_5001 -1.7 -1.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_4762 -1.6 -1.5 Biotin synthesis protein BioH compare
Pf6N2E2_2825 -1.6 -5.5 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_5006 -1.6 -4.5 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_5605 -1.6 -1.9 FxsA protein compare
Pf6N2E2_3258 -1.6 -2.4 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_309 -1.6 -1.4 FIG00957702: hypothetical protein compare
Pf6N2E2_1545 -1.6 -2.9 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_146 -1.6 -0.8 Transcriptional regulator, MarR family compare
Pf6N2E2_4372 -1.6 -1.5 FIG00460773: hypothetical protein compare
Pf6N2E2_2381 -1.6 -3.6 Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3847 -1.6 -4.0 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_2823 -1.6 -3.8 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_2286 -1.6 -2.0 FIG00953287: hypothetical protein compare
Pf6N2E2_311 -1.6 -3.6 hypothetical protein compare
Pf6N2E2_689 -1.6 -2.2 FIG00956189: hypothetical protein compare
Pf6N2E2_2513 -1.6 -1.8 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_1778 -1.6 -3.1 Positive regulator of CheA protein activity (CheW) compare
Pf6N2E2_5153 -1.6 -4.9 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_4423 -1.5 -2.8 FIG00953342: hypothetical protein compare
Pf6N2E2_2681 -1.5 -2.3 3-phosphoglycerate kinase compare
Pf6N2E2_2384 -1.5 -2.5 CmpX compare
Pf6N2E2_2022 -1.5 -2.6 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_3261 -1.5 -6.7 hypothetical protein compare
Pf6N2E2_1340 -1.5 -2.0 major pilin protein fimA compare
Pf6N2E2_1512 -1.5 -2.0 Thiamin biosynthesis lipoprotein ApbE compare
Pf6N2E2_3933 -1.5 -6.6 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_3885 -1.5 -1.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2065 -1.5 -2.1 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_601 -1.5 -3.1 GlpG protein (membrane protein of glp regulon) compare
Pf6N2E2_3938 -1.5 -9.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_1797 -1.5 -1.7 Transcriptional regulator compare
Pf6N2E2_5793 -1.5 -5.0 Aspartyl aminopeptidase compare
Pf6N2E2_5342 -1.5 -1.6 21 kDa hemolysin precursor compare
Pf6N2E2_5575 -1.5 -2.3 Glycerol uptake facilitator protein compare
Pf6N2E2_1056 -1.5 -0.7 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_1090 -1.4 -3.8 Transcriptional regulator for ferulate or vanillate catabolism compare
Pf6N2E2_5667 -1.4 -6.3 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_1283 -1.4 -1.5 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3825 -1.4 -3.5 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_816 -1.4 -5.0 Chemotaxis protein methyltransferase CheR (EC 2.1.1.80) compare
Pf6N2E2_4013 -1.4 -6.6 5-aminovalerate transaminase (EC 2.6.1.48) (from data) compare
Pf6N2E2_4416 -1.4 -2.0 Tyrosine recombinase XerC compare
Pf6N2E2_3899 -1.4 -6.0 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_4969 -1.4 -1.4 hypothetical protein compare
Pf6N2E2_3060 -1.4 -2.0 Outer membrane protein H precursor compare
Pf6N2E2_5560 -1.4 -2.5 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf6N2E2_3260 -1.4 -3.2 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_248 -1.3 -4.4 hypothetical protein compare
Pf6N2E2_2824 -1.3 -6.8 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2756 -1.3 -4.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_2325 -1.3 -5.1 Recombination protein RecR compare
Pf6N2E2_3477 -1.3 -0.9 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_4599 -1.3 -2.4 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4162 -1.3 -3.6 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_4479 -1.3 -1.5 FIG001590: Putative conserved exported protein precursor compare
Pf6N2E2_2526 -1.3 -3.9 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_5328 -1.3 -4.3 FIG00958649: hypothetical protein compare
Pf6N2E2_405 -1.3 -1.7 hypothetical protein compare
Pf6N2E2_882 -1.3 -3.1 FIG00961517: hypothetical protein compare
Pf6N2E2_5733 -1.3 -3.0 NLP/P60 family protein compare
Pf6N2E2_5743 -1.3 -4.0 Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) compare
Pf6N2E2_2133 -1.3 -5.5 Putative sulfate permease compare
Pf6N2E2_2386 -1.3 -2.2 Magnesium and cobalt transport protein CorA compare
Pf6N2E2_4517 -1.3 -3.9 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
Pf6N2E2_3095 -1.3 -0.4 hypothetical protein compare
Pf6N2E2_4638 -1.3 -1.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_479 -1.3 -2.2 Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (EC 2.3.1.168) (from data) compare
Pf6N2E2_1625 -1.3 -3.1 Ferric reductase (1.6.99.14) compare
Pf6N2E2_5160 -1.2 -1.1 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4601 -1.2 -1.5 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_2885 -1.2 -4.6 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_1315 -1.2 -1.5 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) compare
Pf6N2E2_4764 -1.2 -3.8 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_3257 -1.2 -1.4 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_2852 -1.2 -6.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_3537 -1.2 -2.0 Cobalt-precorrin-6x reductase (EC 1.3.1.54) compare
Pf6N2E2_5780 -1.2 -5.3 Periplasmic protease compare
Pf6N2E2_2440 -1.2 -1.2 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_51 -1.2 -4.1 hypothetical protein compare
Pf6N2E2_2218 -1.2 -3.7 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_5965 -1.2 -2.0 transcriptional regulator compare
Pf6N2E2_338 -1.2 -1.1 Transcriptional regulator, AraC family compare
Pf6N2E2_2072 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_3826 -1.2 -3.5 Nitrogen regulation protein NR(I) compare


Specific Phenotypes

For 5 genes in this experiment

For stress Thallium(I) acetate in Pseudomonas fluorescens FW300-N2E2

For stress Thallium(I) acetate across organisms