Experiment set11IT022 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with copper (II) chloride dihydrate 0.03 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -6.3 -4.4 Probable transmembrane protein compare
Pf6N2E2_3782 -6.3 -7.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3932 -5.9 -5.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4826 -5.7 -3.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4564 -5.5 -7.5 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_5177 -5.4 -7.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_2129 -5.2 -3.6 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_3381 -5.1 -7.0 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_71 -5.0 -3.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4048 -4.9 -7.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3842 -4.9 -4.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4278 -4.9 -12.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_64 -4.8 -3.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3752 -4.7 -17.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4825 -4.7 -4.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3382 -4.6 -8.3 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3751 -4.6 -15.3 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3610 -4.6 -4.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3783 -4.5 -6.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4277 -4.5 -14.6 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3253 -4.5 -5.4 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_2073 -4.5 -4.4 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_4597 -4.5 -6.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3630 -4.5 -5.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4279 -4.4 -16.0 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3383 -4.4 -7.9 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4047 -4.1 -4.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3380 -4.1 -12.0 L-lactate permease compare
Pf6N2E2_3841 -4.0 -3.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3384 -4.0 -6.1 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_4596 -4.0 -8.5 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3839 -3.9 -2.7 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_77 -3.8 -3.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_50 -3.8 -9.6 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_4072 -3.8 -9.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_1673 -3.8 -2.2 Transcriptional regulator, TetR family compare
Pf6N2E2_5150 -3.7 -5.6 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3611 -3.7 -3.3 HflC protein compare
Pf6N2E2_1239 -3.7 -6.0 Putative TEGT family carrier/transport protein compare
Pf6N2E2_5175 -3.5 -4.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_1784 -3.5 -3.6 Methyl-accepting chemotaxis protein compare
Pf6N2E2_3251 -3.4 -10.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_66 -3.4 -8.0 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3252 -3.4 -6.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_4797 -3.3 -1.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3940 -3.3 -10.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2588 -3.3 -4.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3696 -3.3 -1.2 hypothetical protein compare
Pf6N2E2_5176 -3.1 -4.2 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3908 -3.1 -2.1 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_302 -3.1 -5.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_5723 -3.0 -7.0 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_2074 -3.0 -1.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4272 -3.0 -2.9 putative membrane protein compare
Pf6N2E2_3826 -2.8 -5.2 Nitrogen regulation protein NR(I) compare
Pf6N2E2_638 -2.8 -3.1 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf6N2E2_4187 -2.8 -9.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4416 -2.8 -1.9 Tyrosine recombinase XerC compare
Pf6N2E2_3170 -2.8 -7.8 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_5153 -2.8 -5.2 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_3264 -2.8 -8.5 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_55 -2.7 -2.5 Probable hydrolase compare
Pf6N2E2_4599 -2.7 -2.6 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_3627 -2.6 -6.5 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) conserved
Pf6N2E2_3261 -2.6 -9.0 hypothetical protein compare
Pf6N2E2_2465 -2.5 -5.1 Cys regulon transcriptional activator CysB compare
Pf6N2E2_63 -2.5 -4.7 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_74 -2.5 -3.0 DedD protein compare
Pf6N2E2_3825 -2.5 -5.8 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_760 -2.5 -11.9 Na+/H+ antiporter NhaB compare
Pf6N2E2_5172 -2.5 -2.8 FOG: TPR repeat compare
Pf6N2E2_3612 -2.4 -2.5 HflK protein compare
Pf6N2E2_5666 -2.4 -11.1 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_1014 -2.4 -1.5 Nitrate/nitrite transporter compare
Pf6N2E2_5679 -2.4 -3.8 hypothetical protein compare
Pf6N2E2_3461 -2.4 -1.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3763 -2.3 -1.5 hypothetical protein compare
Pf6N2E2_1656 -2.3 -1.8 hypothetical protein compare
Pf6N2E2_5574 -2.3 -7.1 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_4476 -2.3 -5.3 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_2267 -2.3 -4.1 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) conserved
Pf6N2E2_4394 -2.3 -5.0 Putrescine utilization regulator compare
Pf6N2E2_4074 -2.3 -16.6 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_601 -2.3 -3.6 GlpG protein (membrane protein of glp regulon) compare
Pf6N2E2_2899 -2.2 -4.4 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_5014 -2.2 -0.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_2574 -2.2 -2.8 Flagellar synthesis regulator FleN compare
Pf6N2E2_3982 -2.2 -1.9 Tryptophan synthase beta chain like (EC 4.2.1.20) compare
Pf6N2E2_1896 -2.2 -1.3 hypothetical protein compare
Pf6N2E2_5728 -2.1 -5.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_5676 -2.1 -4.5 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5704 -2.1 -3.0 Transcriptional regulatory protein PhoP compare
Pf6N2E2_2646 -2.1 -1.3 FIG00953416: hypothetical protein compare
Pf6N2E2_2510 -2.1 -1.4 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_2681 -2.0 -2.8 3-phosphoglycerate kinase compare
Pf6N2E2_1617 -2.0 -1.0 COG2199: FOG: GGDEF domain compare
Pf6N2E2_2823 -2.0 -5.4 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_4584 -2.0 -1.4 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_2261 -2.0 -4.5 VacJ-like lipoprotein precursor compare
Pf6N2E2_5965 -2.0 -2.4 transcriptional regulator compare
Pf6N2E2_5560 -2.0 -2.9 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf6N2E2_4353 -2.0 -4.4 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_1783 -2.0 -2.8 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_4057 -2.0 -0.7 lipoprotein, putative compare
Pf6N2E2_4059 -1.9 -0.7 DNA-binding protein HU-alpha compare
Pf6N2E2_5258 -1.9 -8.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_1502 -1.9 -1.3 Two-component system regulatory protein compare
Pf6N2E2_4988 -1.9 -3.5 Antiholin-like protein LrgA compare
Pf6N2E2_5103 -1.9 -1.4 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_4206 -1.9 -1.7 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_4414 -1.9 -1.2 FIG00953808: hypothetical protein compare
Pf6N2E2_2675 -1.9 -1.1 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_3786 -1.8 -8.4 Twin-arginine translocation protein TatC compare
Pf6N2E2_2285 -1.8 -2.1 FIG00954079: hypothetical protein compare
Pf6N2E2_2277 -1.8 -2.5 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2281 -1.8 -2.9 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_3933 -1.8 -6.8 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_895 -1.8 -3.5 Transcriptional regulator, HxlR family compare
Pf6N2E2_5236 -1.8 -3.3 hypothetical protein compare
Pf6N2E2_2072 -1.8 -3.8 hypothetical protein compare
Pf6N2E2_4579 -1.8 -1.2 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_3300 -1.8 -3.0 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_3938 -1.8 -9.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_4372 -1.7 -1.2 FIG00460773: hypothetical protein compare
Pf6N2E2_2424 -1.7 -3.3 Molybdopterin-guanine dinucleotide biosynthesis protein MobA compare
Pf6N2E2_5257 -1.7 -8.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_5328 -1.7 -3.9 FIG00958649: hypothetical protein compare
Pf6N2E2_4075 -1.7 -6.2 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_2753 -1.7 -1.6 HtrA protease/chaperone protein compare
Pf6N2E2_37 -1.7 -2.2 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_2022 -1.7 -1.6 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_3132 -1.7 -3.1 FIG00954548: hypothetical protein compare
Pf6N2E2_4071 -1.7 -3.1 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_4803 -1.6 -1.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_6140 -1.6 -0.8 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_3060 -1.6 -2.9 Outer membrane protein H precursor compare
Pf6N2E2_5178 -1.6 -2.5 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_1917 -1.6 -2.6 hypothetical protein compare
Pf6N2E2_5188 -1.6 -2.5 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4013 -1.6 -7.1 5-aminovalerate transaminase (EC 2.6.1.48) (from data) compare
Pf6N2E2_2480 -1.6 -0.8 FIG00957636: hypothetical protein compare
Pf6N2E2_4391 -1.6 -5.2 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_5536 -1.6 -1.0 Holliday junction DNA helicase RuvA compare
Pf6N2E2_5780 -1.6 -5.8 Periplasmic protease compare
Pf6N2E2_5001 -1.6 -1.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_5794 -1.6 -1.3 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_5906 -1.6 -1.8 Flp pilus assembly protein, pilin Flp compare
Pf6N2E2_1545 -1.6 -2.4 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_659 -1.5 -1.5 Transcriptional regulatory protein ompR compare
Pf6N2E2_2518 -1.5 -2.1 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_2274 -1.5 -3.3 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_3351 -1.5 -2.8 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_3635 -1.5 -1.7 FIG00953138: hypothetical protein compare
Pf6N2E2_2885 -1.5 -4.8 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_2133 -1.5 -5.9 Putative sulfate permease compare
Pf6N2E2_3077 -1.5 -1.7 FIG138056: a glutathione-dependent thiol reductase compare
Pf6N2E2_5575 -1.5 -1.5 Glycerol uptake facilitator protein compare
Pf6N2E2_2824 -1.5 -6.4 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_5342 -1.5 -1.4 21 kDa hemolysin precursor compare
Pf6N2E2_3941 -1.5 -1.7 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5006 -1.5 -4.3 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3885 -1.5 -1.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2265 -1.5 -3.1 Copper tolerance protein compare
Pf6N2E2_4763 -1.5 -5.8 Biotin synthesis protein BioC compare
Pf6N2E2_1606 -1.5 -3.9 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_3499 -1.5 -3.0 Permeases of the major facilitator superfamily compare
Pf6N2E2_51 -1.5 -4.8 hypothetical protein compare
Pf6N2E2_1705 -1.5 -1.9 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_2852 -1.5 -6.3 GGDEF domain/EAL domain protein compare
Pf6N2E2_2367 -1.5 -0.9 hypothetical protein compare
Pf6N2E2_4305 -1.4 -1.0 FIG00959590: hypothetical protein compare
Pf6N2E2_813 -1.4 -3.1 Response regulator compare
Pf6N2E2_1797 -1.4 -2.1 Transcriptional regulator compare
Pf6N2E2_906 -1.4 -2.1 ISPpu14, transposase Orf2 compare
Pf6N2E2_2810 -1.4 -3.7 Cardiolipin synthetase (EC 2.7.8.-) compare
Pf6N2E2_2121 -1.4 -1.4 hypothetical protein compare
Pf6N2E2_2605 -1.4 -9.8 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_3258 -1.4 -2.7 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_1501 -1.4 -2.2 Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) (EC 3.6.1.17) compare
Pf6N2E2_3770 -1.4 -1.3 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_6100 -1.4 -1.4 tRNA-Val-TAC compare
Pf6N2E2_3738 -1.4 -2.8 General secretion pathway protein L compare
Pf6N2E2_5496 -1.4 -2.5 FIG00953991: hypothetical protein compare
Pf6N2E2_58 -1.4 -2.0 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_5640 -1.3 -1.4 FIG00955597: hypothetical protein compare
Pf6N2E2_3072 -1.3 -6.4 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_2186 -1.3 -4.1 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_4273 -1.3 -6.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_3179 -1.3 -2.1 FIG021952: putative membrane protein compare
Pf6N2E2_5545 -1.3 -3.1 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_3677 -1.3 -7.3 Sensory box/GGDEF family protein compare
Pf6N2E2_2258 -1.3 -6.4 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3737 -1.3 -1.7 General secretion pathway protein M compare
Pf6N2E2_2111 -1.3 -2.1 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit A (from data) compare
Pf6N2E2_5669 -1.3 -5.2 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_3487 -1.3 -5.8 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_248 -1.3 -3.9 hypothetical protein compare
Pf6N2E2_4762 -1.3 -1.6 Biotin synthesis protein BioH compare
Pf6N2E2_987 -1.3 -0.8 hypothetical protein compare
Pf6N2E2_4516 -1.3 -6.1 Putrescine transport system permease protein PotH (TC 3.A.1.11.2) compare


Specific Phenotypes

For 5 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N2E2

For stress copper (II) chloride dihydrate across organisms