Experiment set11IT021 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with copper (II) chloride dihydrate 0.03 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -6.3 -4.4 Probable transmembrane protein compare
Pf6N2E2_3782 -6.0 -7.1 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_4048 -5.5 -5.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_2129 -5.2 -3.6 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_3630 -5.1 -3.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5177 -5.0 -9.5 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4826 -5.0 -6.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_71 -5.0 -3.4 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3380 -4.9 -10.5 L-lactate permease compare
Pf6N2E2_3382 -4.9 -7.5 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4825 -4.8 -3.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3381 -4.8 -8.1 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_3842 -4.8 -4.7 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3253 -4.7 -4.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3752 -4.7 -18.2 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_77 -4.7 -3.2 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3610 -4.6 -4.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2073 -4.6 -3.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3611 -4.6 -2.7 HflC protein compare
Pf6N2E2_4564 -4.5 -10.4 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3783 -4.5 -6.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3383 -4.4 -7.3 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3751 -4.4 -13.2 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_4279 -4.3 -15.5 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4597 -4.2 -7.0 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3932 -4.2 -6.9 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3612 -4.2 -2.9 HflK protein compare
Pf6N2E2_3841 -4.1 -2.9 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4047 -4.0 -4.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4596 -4.0 -8.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4278 -4.0 -14.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_302 -4.0 -5.3 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4601 -3.7 -2.3 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_66 -3.7 -9.6 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3839 -3.7 -3.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3940 -3.6 -10.9 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_64 -3.6 -2.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4072 -3.5 -8.4 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_5175 -3.4 -5.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_2121 -3.4 -2.3 hypothetical protein compare
Pf6N2E2_3627 -3.4 -8.2 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) conserved
Pf6N2E2_3826 -3.3 -6.7 Nitrogen regulation protein NR(I) compare
Pf6N2E2_50 -3.3 -7.4 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5316 -3.3 -2.2 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4187 -3.2 -9.1 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_1083 -3.2 -2.0 hypothetical protein compare
Pf6N2E2_4277 -3.2 -9.9 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_5328 -3.2 -6.7 FIG00958649: hypothetical protein compare
Pf6N2E2_5571 -3.2 -2.2 hypothetical protein compare
Pf6N2E2_1673 -3.1 -2.6 Transcriptional regulator, TetR family compare
Pf6N2E2_4762 -3.1 -3.2 Biotin synthesis protein BioH compare
Pf6N2E2_3264 -3.1 -6.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3252 -3.1 -7.1 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3251 -3.1 -10.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_2074 -3.0 -1.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3825 -3.0 -4.1 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_2899 -3.0 -5.9 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_3261 -2.9 -17.1 hypothetical protein compare
Pf6N2E2_5176 -2.9 -4.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5723 -2.9 -7.5 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_3908 -2.8 -3.4 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5728 -2.8 -6.4 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4272 -2.8 -2.7 putative membrane protein compare
Pf6N2E2_89 -2.8 -2.3 hypothetical protein compare
Pf6N2E2_4394 -2.8 -4.6 Putrescine utilization regulator compare
Pf6N2E2_3003 -2.8 -2.1 Bacteriophage protein GP46 compare
Pf6N2E2_2465 -2.8 -5.2 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4416 -2.7 -1.9 Tyrosine recombinase XerC compare
Pf6N2E2_5605 -2.7 -2.5 FxsA protein compare
Pf6N2E2_1239 -2.7 -7.0 Putative TEGT family carrier/transport protein compare
Pf6N2E2_2519 -2.7 -1.0 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_3300 -2.7 -3.1 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_2267 -2.7 -4.6 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) conserved
Pf6N2E2_2588 -2.7 -3.5 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_760 -2.6 -13.2 Na+/H+ antiporter NhaB compare
Pf6N2E2_3077 -2.6 -2.3 FIG138056: a glutathione-dependent thiol reductase compare
Pf6N2E2_156 -2.5 -2.9 Carbon storage regulator compare
Pf6N2E2_5950 -2.5 -2.4 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_5679 -2.5 -4.1 hypothetical protein compare
Pf6N2E2_5574 -2.5 -7.1 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_63 -2.5 -3.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2675 -2.5 -1.3 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_1676 -2.4 -2.7 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_5153 -2.4 -4.7 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_3763 -2.4 -1.4 hypothetical protein compare
Pf6N2E2_3666 -2.3 -3.1 InaA protein compare
Pf6N2E2_3461 -2.3 -1.4 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_5150 -2.3 -5.6 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_5704 -2.3 -3.4 Transcriptional regulatory protein PhoP compare
Pf6N2E2_2065 -2.3 -1.5 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_5841 -2.3 -0.8 GlcG protein compare
Pf6N2E2_5160 -2.2 -1.1 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_4797 -2.2 -2.0 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_3384 -2.2 -4.7 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_659 -2.2 -2.7 Transcriptional regulatory protein ompR compare
Pf6N2E2_4074 -2.2 -16.2 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_3941 -2.2 -1.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2681 -2.2 -2.8 3-phosphoglycerate kinase compare
Pf6N2E2_1896 -2.2 -1.3 hypothetical protein compare
Pf6N2E2_5014 -2.1 -0.8 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_5919 -2.1 -3.1 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_4013 -2.1 -8.0 5-aminovalerate transaminase (EC 2.6.1.48) (from data) compare
Pf6N2E2_5794 -2.1 -1.2 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_2133 -2.0 -6.7 Putative sulfate permease compare
Pf6N2E2_3170 -2.0 -5.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4962 -2.0 -4.3 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_5676 -2.0 -4.4 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_2999 -2.0 -2.3 probable tail fiber assembly protein compare
Pf6N2E2_5666 -2.0 -9.6 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5527 -2.0 -1.3 Cold shock protein CspC compare
Pf6N2E2_2646 -2.0 -1.2 FIG00953416: hypothetical protein compare
Pf6N2E2_2823 -2.0 -5.1 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_2261 -2.0 -4.3 VacJ-like lipoprotein precursor compare
Pf6N2E2_3696 -2.0 -1.0 hypothetical protein compare
Pf6N2E2_1705 -1.9 -2.1 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_4059 -1.9 -0.7 DNA-binding protein HU-alpha compare
Pf6N2E2_3720 -1.9 -2.5 FIG027190: Putative transmembrane protein compare
Pf6N2E2_1014 -1.9 -1.3 Nitrate/nitrite transporter compare
Pf6N2E2_3849 -1.9 -1.9 FIG00954739: hypothetical protein compare
Pf6N2E2_1545 -1.9 -2.1 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_3786 -1.9 -10.7 Twin-arginine translocation protein TatC compare
Pf6N2E2_2277 -1.8 -2.6 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3938 -1.8 -11.6 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3138 -1.8 -4.7 YaeQ protein compare
Pf6N2E2_4476 -1.8 -3.4 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_3568 -1.8 -2.4 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_5965 -1.8 -2.4 transcriptional regulator compare
Pf6N2E2_4414 -1.8 -1.2 FIG00953808: hypothetical protein compare
Pf6N2E2_237 -1.8 -2.3 hypothetical protein compare
Pf6N2E2_5342 -1.8 -1.2 21 kDa hemolysin precursor compare
Pf6N2E2_3534 -1.8 -2.8 Cobalamin biosynthesis protein CobG compare
Pf6N2E2_2852 -1.8 -6.4 GGDEF domain/EAL domain protein compare
Pf6N2E2_5188 -1.8 -2.6 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_1683 -1.8 -2.0 Fe2+-dicitrate sensor, membrane component compare
Pf6N2E2_5006 -1.7 -4.2 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4515 -1.7 -8.0 Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2) compare
Pf6N2E2_4399 -1.7 -5.1 GGDEF domain/EAL domain protein compare
Pf6N2E2_5178 -1.7 -2.9 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_4579 -1.7 -1.2 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_3325 -1.7 -1.6 ABC transporter, ATP-binding protein compare
Pf6N2E2_4162 -1.7 -3.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_4764 -1.7 -4.2 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_2274 -1.7 -3.4 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_895 -1.7 -4.2 Transcriptional regulator, HxlR family compare
Pf6N2E2_2386 -1.7 -1.6 Magnesium and cobalt transport protein CorA compare
Pf6N2E2_2375 -1.7 -2.8 Response regulator NasT compare
Pf6N2E2_5534 -1.7 -1.9 FIG000859: hypothetical protein YebC compare
Pf6N2E2_3820 -1.7 -2.8 hypothetical protein compare
Pf6N2E2_4216 -1.7 -2.7 Transcriptional regulator of glmS gene, DeoR family compare
Pf6N2E2_4391 -1.7 -5.2 D-amino acid dehydrogenase small subunit (EC 1.4.99.1) compare
Pf6N2E2_3258 -1.7 -2.5 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_4803 -1.6 -1.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_2022 -1.6 -1.9 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_2514 -1.6 -3.1 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_6140 -1.6 -0.8 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_1797 -1.6 -2.2 Transcriptional regulator compare
Pf6N2E2_5156 -1.6 -1.1 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5667 -1.6 -7.2 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_6100 -1.6 -1.3 tRNA-Val-TAC compare
Pf6N2E2_5536 -1.6 -1.0 Holliday junction DNA helicase RuvA compare
Pf6N2E2_2480 -1.6 -0.8 FIG00957636: hypothetical protein compare
Pf6N2E2_248 -1.6 -4.3 hypothetical protein compare
Pf6N2E2_3589 -1.6 -1.2 Lysine decarboxylase family compare
Pf6N2E2_51 -1.6 -5.2 hypothetical protein compare
Pf6N2E2_2885 -1.5 -4.9 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_5669 -1.5 -5.1 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_2861 -1.5 -3.7 hypothetical protein compare
Pf6N2E2_953 -1.5 -1.8 FIG00958851: hypothetical protein compare
Pf6N2E2_4372 -1.5 -1.7 FIG00460773: hypothetical protein compare
Pf6N2E2_689 -1.5 -2.1 FIG00956189: hypothetical protein compare
Pf6N2E2_3778 -1.5 -2.6 FIG00954300: hypothetical protein compare
Pf6N2E2_2605 -1.5 -10.7 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_5579 -1.5 -5.8 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_5258 -1.5 -5.4 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4071 -1.4 -3.5 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_1352 -1.4 -2.2 Cation transport ATPase compare
Pf6N2E2_3885 -1.4 -1.0 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_2824 -1.4 -6.7 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_5103 -1.4 -1.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2518 -1.4 -2.4 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_2810 -1.4 -3.5 Cardiolipin synthetase (EC 2.7.8.-) compare
Pf6N2E2_928 -1.4 -2.0 Copper metallochaperone, bacterial analog of Cox17 protein compare
Pf6N2E2_4763 -1.4 -6.1 Biotin synthesis protein BioC compare
Pf6N2E2_5428 -1.4 -5.3 DNA recombination and repair protein RecO compare
Pf6N2E2_2746 -1.4 -3.7 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_3677 -1.4 -8.9 Sensory box/GGDEF family protein compare
Pf6N2E2_3060 -1.4 -1.7 Outer membrane protein H precursor compare
Pf6N2E2_3933 -1.4 -5.2 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_4014 -1.4 -5.6 Succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16) compare
Pf6N2E2_4988 -1.4 -3.5 Antiholin-like protein LrgA compare
Pf6N2E2_923 -1.4 -1.5 Haloacid dehalogenase, type II (EC 3.8.1.2) compare
Pf6N2E2_2068 -1.4 -3.6 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_3072 -1.4 -7.0 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_5575 -1.4 -2.0 Glycerol uptake facilitator protein compare
Pf6N2E2_1932 -1.3 -3.0 Transcriptional regulator, IclR family compare
Pf6N2E2_572 -1.3 -2.0 hypothetical protein compare
Pf6N2E2_3074 -1.3 -1.4 FIG00960973: hypothetical protein compare
Pf6N2E2_5738 -1.3 -4.3 Cobyrinic acid A,C-diamide synthase compare
Pf6N2E2_3271 -1.3 -1.8 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_5257 -1.3 -7.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare


Specific Phenotypes

For 7 genes in this experiment

For stress copper (II) chloride dihydrate in Pseudomonas fluorescens FW300-N2E2

For stress copper (II) chloride dihydrate across organisms