Experiment set11IT018 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with Cobalt chloride hexahydrate 0.02 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -6.7 -4.6 Probable transmembrane protein compare
Pf6N2E2_3782 -6.2 -8.4 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3783 -5.6 -5.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_2129 -5.6 -3.9 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_5177 -5.5 -9.1 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3630 -5.4 -3.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3932 -5.4 -7.3 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4826 -5.3 -6.3 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_64 -5.2 -3.6 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3381 -5.1 -8.5 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_4597 -5.0 -5.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_71 -4.9 -4.8 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3611 -4.8 -3.0 HflC protein compare
Pf6N2E2_3384 -4.8 -6.5 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_3842 -4.8 -5.6 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_77 -4.7 -4.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3253 -4.7 -5.6 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_66 -4.7 -9.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4825 -4.6 -6.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3751 -4.5 -13.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3382 -4.5 -9.6 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4278 -4.4 -14.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_2073 -4.4 -7.3 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3752 -4.4 -22.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4048 -4.3 -9.9 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_2681 -4.3 -2.9 3-phosphoglycerate kinase compare
Pf6N2E2_3826 -4.3 -6.5 Nitrogen regulation protein NR(I) compare
Pf6N2E2_4279 -4.2 -14.9 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_4564 -4.0 -8.3 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4596 -4.0 -9.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3612 -3.9 -4.6 HflK protein compare
Pf6N2E2_4047 -3.9 -5.3 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3841 -3.8 -5.2 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_2121 -3.8 -2.6 hypothetical protein compare
Pf6N2E2_1032 -3.8 -1.4 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_3383 -3.8 -5.7 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_50 -3.8 -10.9 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_3839 -3.7 -4.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_5175 -3.7 -6.1 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4277 -3.6 -10.9 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_5150 -3.6 -6.7 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3380 -3.5 -10.7 L-lactate permease compare
Pf6N2E2_302 -3.4 -6.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3940 -3.4 -10.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3252 -3.4 -7.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5176 -3.3 -5.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_2074 -3.3 -1.7 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3610 -3.2 -6.3 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_4072 -3.1 -9.4 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_3251 -3.1 -12.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5723 -3.0 -8.6 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_63 -3.0 -4.0 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4416 -3.0 -2.0 Tyrosine recombinase XerC compare
Pf6N2E2_2519 -3.0 -1.1 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_2899 -2.8 -6.0 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_5728 -2.7 -6.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_1673 -2.7 -2.5 Transcriptional regulator, TetR family compare
Pf6N2E2_3627 -2.6 -8.1 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) compare
Pf6N2E2_3461 -2.6 -1.6 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3908 -2.5 -5.1 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5574 -2.5 -8.4 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_5679 -2.5 -5.3 hypothetical protein compare
Pf6N2E2_919 -2.5 -2.1 FIG00954373: hypothetical protein compare
Pf6N2E2_5258 -2.5 -10.3 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_5571 -2.4 -2.7 hypothetical protein compare
Pf6N2E2_2465 -2.4 -4.4 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5178 -2.4 -3.0 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_5153 -2.4 -5.7 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2013 -2.3 -1.2 hypothetical protein compare
Pf6N2E2_3170 -2.3 -6.1 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2646 -2.3 -1.5 FIG00953416: hypothetical protein compare
Pf6N2E2_5666 -2.3 -9.5 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5014 -2.3 -0.9 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_760 -2.3 -11.1 Na+/H+ antiporter NhaB compare
Pf6N2E2_4797 -2.3 -1.8 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_1239 -2.3 -8.3 Putative TEGT family carrier/transport protein compare
Pf6N2E2_4394 -2.2 -5.1 Putrescine utilization regulator compare
Pf6N2E2_3825 -2.2 -3.6 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_3514 -2.2 -1.5 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_3300 -2.2 -3.5 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_3261 -2.2 -8.9 hypothetical protein compare
Pf6N2E2_3666 -2.2 -3.2 InaA protein compare
Pf6N2E2_4272 -2.1 -3.2 putative membrane protein compare
Pf6N2E2_5328 -2.1 -5.1 FIG00958649: hypothetical protein compare
Pf6N2E2_3938 -2.1 -13.0 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2323 -2.1 -1.4 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_1778 -2.0 -3.9 Positive regulator of CheA protein activity (CheW) compare
Pf6N2E2_5342 -2.0 -1.4 21 kDa hemolysin precursor compare
Pf6N2E2_4414 -2.0 -1.3 FIG00953808: hypothetical protein compare
Pf6N2E2_4708 -2.0 -1.8 hypothetical protein compare
Pf6N2E2_4057 -2.0 -0.7 lipoprotein, putative compare
Pf6N2E2_1545 -2.0 -3.0 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_3933 -2.0 -7.8 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_2274 -2.0 -4.5 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2218 -2.0 -5.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2440 -2.0 -1.7 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_4988 -1.9 -4.6 Antiholin-like protein LrgA compare
Pf6N2E2_4579 -1.9 -1.3 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2261 -1.9 -5.4 VacJ-like lipoprotein precursor compare
Pf6N2E2_5257 -1.9 -9.6 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2518 -1.9 -3.9 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_4298 -1.9 -4.0 Uncharacterized protein ImpB compare
Pf6N2E2_2022 -1.8 -2.6 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_5536 -1.8 -1.2 Holliday junction DNA helicase RuvA compare
Pf6N2E2_3899 -1.8 -8.1 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_4803 -1.8 -1.2 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_5156 -1.8 -1.2 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_2984 -1.8 -2.1 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_3033 -1.8 -1.5 hypothetical protein compare
Pf6N2E2_2286 -1.8 -2.1 FIG00953287: hypothetical protein compare
Pf6N2E2_5704 -1.8 -2.8 Transcriptional regulatory protein PhoP compare
Pf6N2E2_3770 -1.8 -1.2 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_3258 -1.8 -2.9 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5676 -1.8 -3.0 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5575 -1.8 -1.7 Glycerol uptake facilitator protein compare
Pf6N2E2_1606 -1.8 -5.2 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_2675 -1.8 -1.3 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_5667 -1.7 -9.3 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3264 -1.7 -5.9 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_2510 -1.7 -2.5 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3763 -1.7 -1.5 hypothetical protein compare
Pf6N2E2_2588 -1.7 -3.1 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_4049 -1.7 -7.2 Glycine cleavage system transcriptional activator compare
Pf6N2E2_895 -1.7 -4.9 Transcriptional regulator, HxlR family compare
Pf6N2E2_146 -1.7 -0.9 Transcriptional regulator, MarR family compare
Pf6N2E2_4187 -1.7 -9.0 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2810 -1.6 -4.2 Cardiolipin synthetase (EC 2.7.8.-) compare
Pf6N2E2_4074 -1.6 -12.6 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_4372 -1.6 -2.1 FIG00460773: hypothetical protein compare
Pf6N2E2_5739 -1.6 -1.4 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_5669 -1.6 -7.3 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_2258 -1.6 -8.3 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3480 -1.6 -0.8 Transcriptional regulator, ArsR family compare
Pf6N2E2_5967 -1.5 -2.5 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) (from data) compare
Pf6N2E2_4599 -1.5 -2.6 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_1676 -1.5 -2.4 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_1113 -1.5 -1.3 Transcriptional regulator, TetR family compare
Pf6N2E2_3138 -1.5 -4.1 YaeQ protein compare
Pf6N2E2_2065 -1.5 -2.2 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2509 -1.5 -2.0 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_2938 -1.5 -4.5 Outer membrane lipoprotein compare
Pf6N2E2_5534 -1.5 -2.7 FIG000859: hypothetical protein YebC compare
Pf6N2E2_396 -1.5 -3.3 hypothetical protein compare
Pf6N2E2_2110 -1.5 -2.7 LysR family transcriptional regulator near succinyl-CoA:3-ketoacid-coenzyme A transferase compare
Pf6N2E2_2992 -1.5 -3.7 Regulatory protein RecX compare
Pf6N2E2_2885 -1.5 -4.2 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_2325 -1.5 -4.4 Recombination protein RecR compare
Pf6N2E2_70 -1.5 -3.5 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3351 -1.5 -3.0 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_4331 -1.4 -4.0 hypothetical protein compare
Pf6N2E2_3257 -1.4 -1.3 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_2753 -1.4 -1.8 HtrA protease/chaperone protein compare
Pf6N2E2_4039 -1.4 -5.4 NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2) compare
Pf6N2E2_5746 -1.4 -3.1 Cobalamin synthase compare
Pf6N2E2_1870 -1.4 -2.5 hypothetical protein compare
Pf6N2E2_2384 -1.4 -2.7 CmpX compare
Pf6N2E2_3134 -1.4 -1.0 hypothetical protein compare
Pf6N2E2_4206 -1.4 -1.9 Chromosome (plasmid) partitioning protein ParB compare
Pf6N2E2_2277 -1.4 -2.2 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_1797 -1.4 -1.7 Transcriptional regulator compare
Pf6N2E2_2217 -1.4 -4.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_342 -1.4 -1.0 DNA-binding response regulator compare
Pf6N2E2_1776 -1.4 -2.0 Chemotaxis protein CheD compare
Pf6N2E2_4584 -1.4 -1.7 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_5579 -1.4 -4.9 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_2752 -1.3 -4.8 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3095 -1.3 -0.5 hypothetical protein compare
Pf6N2E2_4517 -1.3 -3.7 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
Pf6N2E2_417 -1.3 -1.7 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf6N2E2_51 -1.3 -4.6 hypothetical protein compare
Pf6N2E2_3072 -1.3 -6.7 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_2264 -1.3 -2.6 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_3834 -1.3 -4.4 Lipoprotein NlpD compare
Pf6N2E2_3004 -1.3 -2.3 Prophage baseplate assembly protein V compare
Pf6N2E2_2513 -1.3 -1.5 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_1920 -1.3 -1.8 Rubredoxin compare
Pf6N2E2_2186 -1.3 -3.9 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_5243 -1.3 -1.6 hypothetical protein compare
Pf6N2E2_5277 -1.3 -5.8 FIG00953110: hypothetical protein compare
Pf6N2E2_5520 -1.3 -5.6 Sensory box histidine kinase compare
Pf6N2E2_1441 -1.3 -2.2 Uncharacterized oxidoreductase ydgJ (EC 1.-.-.-) compare
Pf6N2E2_2586 -1.3 -1.7 Hpt domain protein compare
Pf6N2E2_1656 -1.3 -1.1 hypothetical protein compare
Pf6N2E2_3885 -1.3 -1.2 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_953 -1.3 -2.4 FIG00958851: hypothetical protein compare
Pf6N2E2_813 -1.3 -3.1 Response regulator compare
Pf6N2E2_248 -1.2 -4.5 hypothetical protein compare
Pf6N2E2_1153 -1.2 -3.1 small molecule metabolism; degradation; fatty acid compare
Pf6N2E2_601 -1.2 -2.8 GlpG protein (membrane protein of glp regulon) compare
Pf6N2E2_5103 -1.2 -1.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2367 -1.2 -0.9 hypothetical protein compare
Pf6N2E2_4423 -1.2 -2.6 FIG00953342: hypothetical protein compare
Pf6N2E2_4661 -1.2 -3.0 KluA regulatory protein compare
Pf6N2E2_442 -1.2 -2.6 FIG00962345: hypothetical protein compare
Pf6N2E2_2746 -1.2 -3.9 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_4684 -1.2 -3.9 hypothetical protein compare
Pf6N2E2_2386 -1.2 -2.2 Magnesium and cobalt transport protein CorA compare
Pf6N2E2_2133 -1.2 -4.6 Putative sulfate permease compare
Pf6N2E2_5965 -1.2 -1.9 transcriptional regulator compare
Pf6N2E2_1504 -1.2 -2.7 putative 2-pyrone-4,6-dicarboxylic acid hydrolase compare


Specific Phenotypes

For 3 genes in this experiment

For stress Cobalt chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Cobalt chloride hexahydrate across organisms