Experiment set11IT017 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with Cobalt chloride hexahydrate 0.04 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3782 -6.1 -7.3 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3060 -5.9 -3.2 Outer membrane protein H precursor compare
Pf6N2E2_2251 -5.8 -5.6 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) conserved
Pf6N2E2_3783 -5.5 -3.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_4071 -5.5 -5.3 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5177 -5.3 -7.2 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_2129 -5.2 -3.5 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_3381 -5.1 -6.1 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_3383 -4.9 -5.9 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4048 -4.9 -6.7 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3630 -4.9 -3.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5679 -4.8 -3.3 hypothetical protein compare
Pf6N2E2_3248 -4.8 -5.6 Probable transmembrane protein compare
Pf6N2E2_3253 -4.7 -3.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_64 -4.7 -2.8 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4826 -4.7 -6.4 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3382 -4.6 -7.7 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_77 -4.6 -3.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3751 -4.6 -16.4 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3264 -4.5 -6.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3932 -4.4 -6.7 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4072 -4.4 -8.0 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_71 -4.4 -5.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4564 -4.3 -9.6 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4187 -4.3 -12.1 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5728 -4.3 -6.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4597 -4.3 -5.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3752 -4.3 -19.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4825 -4.2 -6.3 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_5178 -4.1 -4.0 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_3270 -4.1 -5.6 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_4047 -4.1 -2.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_2574 -4.0 -2.5 Flagellar synthesis regulator FleN compare
Pf6N2E2_3665 -4.0 -1.3 serine/threonine protein kinase compare
Pf6N2E2_5111 -4.0 -3.1 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_3842 -3.9 -4.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_3612 -3.9 -2.7 HflK protein compare
Pf6N2E2_4596 -3.7 -7.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3841 -3.7 -3.6 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3610 -3.7 -4.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_1673 -3.7 -1.9 Transcriptional regulator, TetR family compare
Pf6N2E2_3661 -3.7 -2.5 hypothetical protein compare
Pf6N2E2_3839 -3.6 -2.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_66 -3.6 -8.4 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3384 -3.5 -5.2 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_4074 -3.5 -18.5 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_3611 -3.5 -2.7 HflC protein compare
Pf6N2E2_302 -3.5 -5.2 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3380 -3.4 -8.9 L-lactate permease compare
Pf6N2E2_4277 -3.4 -11.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3021 -3.4 -1.1 hypothetical protein compare
Pf6N2E2_2073 -3.4 -7.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_2218 -3.3 -3.2 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2217 -3.3 -5.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_2121 -3.3 -2.1 hypothetical protein compare
Pf6N2E2_2186 -3.3 -7.4 Isovaleryl-CoA dehydrogenase (EC 1.3.8.4) compare
Pf6N2E2_4278 -3.3 -12.4 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3062 -3.3 -3.2 Membrane-associated zinc metalloprotease compare
Pf6N2E2_5258 -3.3 -10.0 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4279 -3.2 -13.9 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_2258 -3.2 -11.3 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_58 -3.2 -2.4 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_5711 -3.2 -7.3 tRNA(Cytosine32)-2-thiocytidine synthetase compare
Pf6N2E2_5573 -3.2 -6.6 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_4797 -3.2 -1.4 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_4075 -3.2 -8.3 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_4364 -3.2 -3.8 Protein YicC compare
Pf6N2E2_5175 -3.1 -5.2 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_3251 -3.1 -10.8 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1656 -3.1 -1.7 hypothetical protein compare
Pf6N2E2_2074 -3.1 -1.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3940 -3.0 -9.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_464 -3.0 -2.0 Sensory histidine kinase QseC compare
Pf6N2E2_5578 -3.0 -9.5 Ferric iron ABC transporter, ATP-binding protein conserved
Pf6N2E2_5316 -3.0 -2.0 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4476 -3.0 -5.5 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_3627 -3.0 -9.1 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) compare
Pf6N2E2_3079 -3.0 -8.6 Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA compare
Pf6N2E2_5520 -3.0 -8.4 Sensory box histidine kinase compare
Pf6N2E2_3252 -2.9 -7.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_5176 -2.9 -3.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4483 -2.9 -16.7 Ferric iron ABC transporter, iron-binding protein conserved
Pf6N2E2_5257 -2.9 -9.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4484 -2.8 -15.4 Ferric iron ABC transporter, permease protein conserved
Pf6N2E2_1776 -2.8 -3.0 Chemotaxis protein CheD compare
Pf6N2E2_3261 -2.8 -12.3 hypothetical protein compare
Pf6N2E2_50 -2.8 -6.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_6140 -2.8 -0.9 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_2605 -2.8 -18.4 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_4453 -2.7 -13.6 Polyphosphate kinase (EC 2.7.4.1) compare
Pf6N2E2_4360 -2.7 -9.5 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_2519 -2.7 -0.8 Biosynthetic Aromatic amino acid aminotransferase beta (EC 2.6.1.57) compare
Pf6N2E2_3487 -2.7 -9.6 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2277 -2.7 -2.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3908 -2.7 -1.9 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_3847 -2.7 -3.6 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_2261 -2.7 -4.0 VacJ-like lipoprotein precursor compare
Pf6N2E2_2488 -2.6 -1.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_55 -2.6 -2.2 Probable hydrolase compare
Pf6N2E2_4624 -2.6 -0.8 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_5006 -2.6 -3.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_2675 -2.6 -1.2 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_3659 -2.6 -6.7 Protein fixF compare
Pf6N2E2_2588 -2.6 -4.1 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_1821 -2.6 -1.6 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system compare
Pf6N2E2_2465 -2.6 -4.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_5919 -2.6 -2.8 Flp pilus assembly protein TadD, contains TPR repeats compare
Pf6N2E2_760 -2.5 -11.4 Na+/H+ antiporter NhaB compare
Pf6N2E2_5723 -2.5 -8.3 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_4974 -2.5 -5.9 DedA protein compare
Pf6N2E2_2852 -2.5 -9.9 GGDEF domain/EAL domain protein compare
Pf6N2E2_4357 -2.5 -11.5 Nucleoside-diphosphate-sugar epimerases conserved
Pf6N2E2_4612 -2.4 -4.3 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_4988 -2.4 -3.5 Antiholin-like protein LrgA compare
Pf6N2E2_4989 -2.4 -3.3 LrgA-associated membrane protein LrgB compare
Pf6N2E2_2534 -2.4 -4.6 Cell division protein BolA compare
Pf6N2E2_3666 -2.3 -2.7 InaA protein compare
Pf6N2E2_1606 -2.3 -5.0 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_2606 -2.3 -10.6 hypothetical protein compare
Pf6N2E2_3351 -2.3 -1.6 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_338 -2.3 -1.4 Transcriptional regulator, AraC family compare
Pf6N2E2_4120 -2.3 -12.0 Trk system potassium uptake protein TrkA compare
Pf6N2E2_3134 -2.3 -1.0 hypothetical protein compare
Pf6N2E2_3868 -2.3 -6.5 Transcriptional regulator, LysR family compare
Pf6N2E2_2264 -2.3 -3.3 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_3081 -2.2 -4.4 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf6N2E2_5078 -2.2 -2.7 Carbon starvation protein A compare
Pf6N2E2_5545 -2.2 -3.6 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_5703 -2.2 -4.7 outer membrane protein H1 compare
Pf6N2E2_3869 -2.2 -11.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_939 -2.2 -2.0 hypothetical protein compare
Pf6N2E2_5160 -2.1 -0.9 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3658 -2.1 -9.2 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_5666 -2.1 -9.7 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_1935 -2.1 -2.8 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_5049 -2.1 -2.5 acetyltransferase, GNAT family compare
Pf6N2E2_2391 -2.1 -8.5 FIG137360: hypothetical protein compare
Pf6N2E2_3820 -2.0 -2.8 hypothetical protein compare
Pf6N2E2_5991 -2.0 -2.2 proteinase inhibitor compare
Pf6N2E2_3461 -2.0 -1.1 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_4570 -2.0 -2.7 Cation/multidrug efflux pump compare
Pf6N2E2_4618 -2.0 -5.5 Chemotaxis signal transduction protein compare
Pf6N2E2_3656 -2.0 -12.7 Probable transcription regulator Mig-14 compare
Pf6N2E2_5014 -2.0 -0.6 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4987 -2.0 -0.6 MaoC-like domain protein compare
Pf6N2E2_4272 -2.0 -3.2 putative membrane protein compare
Pf6N2E2_4614 -2.0 -3.9 twitching motility protein PilH compare
Pf6N2E2_2133 -2.0 -6.4 Putative sulfate permease compare
Pf6N2E2_2425 -2.0 -3.8 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3763 -2.0 -1.0 hypothetical protein compare
Pf6N2E2_5955 -2.0 -3.5 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_4817 -2.0 -13.8 Spermidine Putrescine ABC transporter permease component PotB (TC 3.A.1.11.1) compare
Pf6N2E2_1239 -1.9 -6.4 Putative TEGT family carrier/transport protein compare
Pf6N2E2_4067 -1.9 -7.1 Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3) compare
Pf6N2E2_1797 -1.9 -2.0 Transcriptional regulator compare
Pf6N2E2_2065 -1.9 -1.8 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_1676 -1.9 -2.3 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_3072 -1.9 -8.9 [Protein-PII] uridylyltransferase (EC 2.7.7.59) compare
Pf6N2E2_5574 -1.9 -6.3 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_6045 -1.9 -1.0 hypothetical protein compare
Pf6N2E2_74 -1.9 -2.2 DedD protein compare
Pf6N2E2_1932 -1.9 -3.6 Transcriptional regulator, IclR family compare
Pf6N2E2_5331 -1.9 -4.2 ATPase, AFG1 family compare
Pf6N2E2_5618 -1.9 -10.3 Probable thiol oxidoreductase with 2 cytochrome c heme-binding sites conserved
Pf6N2E2_5153 -1.8 -4.7 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_799 -1.8 -2.5 hypothetical protein compare
Pf6N2E2_4889 -1.8 -4.6 Putative transport protein compare
Pf6N2E2_3826 -1.8 -3.7 Nitrogen regulation protein NR(I) compare
Pf6N2E2_1779 -1.8 -2.4 Positive regulator of CheA protein activity (CheW) compare
Pf6N2E2_659 -1.8 -2.5 Transcriptional regulatory protein ompR compare
Pf6N2E2_63 -1.8 -2.5 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_3170 -1.8 -5.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_88 -1.8 -1.2 hypothetical protein compare
Pf6N2E2_2646 -1.8 -0.9 FIG00953416: hypothetical protein compare
Pf6N2E2_608 -1.8 -6.2 Transcriptional regulator of the arabinose operon in Shewanella, GntR family compare
Pf6N2E2_895 -1.8 -4.5 Transcriptional regulator, HxlR family compare
Pf6N2E2_5157 -1.8 -9.7 Two-component sensor CbrA: intrcellular carbon:nitrogen balance compare
Pf6N2E2_1605 -1.8 -4.8 Carboxynorspermidine dehydrogenase, putative (EC 1.1.1.-) compare
Pf6N2E2_37 -1.8 -2.3 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I compare
Pf6N2E2_5677 -1.8 -1.3 Carbon storage regulator compare
Pf6N2E2_672 -1.7 -2.6 ABC-type polar amino acid transport system, ATPase component compare
Pf6N2E2_2549 -1.7 -0.9 hypothetical protein compare
Pf6N2E2_5950 -1.7 -1.9 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_3040 -1.7 -6.4 5-nucleotidase SurE (EC 3.1.3.5) compare
Pf6N2E2_4273 -1.7 -6.6 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_4057 -1.7 -0.5 lipoprotein, putative compare
Pf6N2E2_1784 -1.7 -2.7 Methyl-accepting chemotaxis protein compare
Pf6N2E2_5659 -1.7 -12.3 Acetyl-coenzyme A synthetase (EC 6.2.1.1) compare
Pf6N2E2_2282 -1.7 -2.0 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_4829 -1.7 -3.2 OsmC/Ohr family protein compare
Pf6N2E2_3240 -1.7 -1.2 Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) compare
Pf6N2E2_5240 -1.7 -4.7 FIG00953775: hypothetical protein compare
Pf6N2E2_2068 -1.7 -3.8 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_2885 -1.7 -5.0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_4413 -1.6 -7.1 FIG004064: hypothetical protein compare
Pf6N2E2_1512 -1.6 -2.7 Thiamin biosynthesis lipoprotein ApbE compare
Pf6N2E2_4381 -1.6 -4.6 hypothetical protein compare
Pf6N2E2_4044 -1.6 -3.2 Holliday junction resolvasome, helicase subunit compare
Pf6N2E2_1463 -1.6 -2.3 Isochorismate pyruvate-lyase (EC 4.-.-.-) compare
Pf6N2E2_3055 -1.6 -2.6 Ribonuclease HII (EC 3.1.26.4) compare


Specific Phenotypes

For 46 genes in this experiment

For stress Cobalt chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Cobalt chloride hexahydrate across organisms