Experiment set11IT014 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with Nickel (II) chloride hexahydrate 0.04 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3248 -5.8 -5.6 Probable transmembrane protein compare
Pf6N2E2_3842 -5.7 -3.9 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5177 -5.5 -8.4 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3381 -5.2 -7.9 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_64 -5.1 -3.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3630 -4.9 -4.8 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4048 -4.9 -8.1 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3783 -4.7 -5.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3382 -4.7 -8.4 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4597 -4.6 -6.3 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4564 -4.5 -10.9 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4279 -4.5 -14.7 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3380 -4.4 -12.7 L-lactate permease compare
Pf6N2E2_2129 -4.3 -3.6 Predicted dye-decolorizing peroxidase (DyP), YfeX-like subgroup compare
Pf6N2E2_3751 -4.3 -15.0 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3253 -4.3 -6.5 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3782 -4.3 -8.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3384 -4.3 -6.3 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_2681 -4.2 -2.9 3-phosphoglycerate kinase compare
Pf6N2E2_4278 -4.2 -14.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3383 -4.2 -8.4 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4047 -4.2 -4.9 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3752 -4.2 -22.0 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3841 -4.1 -4.0 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4825 -4.1 -7.4 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3839 -4.0 -2.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4596 -4.0 -9.2 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_5175 -4.0 -2.7 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_77 -4.0 -4.6 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3264 -3.9 -8.4 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_302 -3.8 -6.7 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4826 -3.8 -7.7 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_50 -3.8 -10.4 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_71 -3.8 -6.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_2073 -3.7 -7.5 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5176 -3.7 -2.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3612 -3.6 -4.2 HflK protein compare
Pf6N2E2_1617 -3.5 -1.2 COG2199: FOG: GGDEF domain compare
Pf6N2E2_4277 -3.4 -11.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_1083 -3.4 -2.0 hypothetical protein compare
Pf6N2E2_3932 -3.3 -7.4 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_2465 -3.2 -6.5 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3940 -3.2 -10.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4072 -3.2 -7.8 Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1) compare
Pf6N2E2_66 -3.2 -7.5 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3610 -3.2 -6.1 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2074 -3.2 -1.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3252 -3.2 -6.3 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3627 -3.0 -7.6 Thiosulfate sulfurtransferase, rhodanese (EC 2.8.1.1) compare
Pf6N2E2_3251 -3.0 -12.1 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3300 -3.0 -3.5 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_63 -2.9 -3.3 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_4416 -2.9 -2.0 Tyrosine recombinase XerC compare
Pf6N2E2_3908 -2.9 -3.4 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5560 -2.9 -2.7 Sigma-54 dependent transcriptional regulator/sensory box protein compare
Pf6N2E2_5723 -2.8 -9.1 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) compare
Pf6N2E2_2375 -2.8 -2.4 Response regulator NasT compare
Pf6N2E2_2588 -2.8 -4.1 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3611 -2.7 -2.6 HflC protein compare
Pf6N2E2_5574 -2.7 -7.9 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_3351 -2.7 -2.6 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_4988 -2.7 -4.6 Antiholin-like protein LrgA compare
Pf6N2E2_5103 -2.6 -1.2 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_601 -2.5 -4.0 GlpG protein (membrane protein of glp regulon) compare
Pf6N2E2_5704 -2.5 -3.4 Transcriptional regulatory protein PhoP compare
Pf6N2E2_5666 -2.5 -11.5 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3763 -2.5 -1.4 hypothetical protein compare
Pf6N2E2_3461 -2.5 -1.4 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3170 -2.5 -7.5 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_1673 -2.5 -2.9 Transcriptional regulator, TetR family compare
Pf6N2E2_4074 -2.4 -17.8 Phosphate transport system permease protein PstC (TC 3.A.1.7.1) compare
Pf6N2E2_3514 -2.4 -2.2 Ribosomal protein L11 methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_5841 -2.4 -0.8 GlcG protein compare
Pf6N2E2_4762 -2.4 -2.7 Biotin synthesis protein BioH compare
Pf6N2E2_2251 -2.4 -6.1 NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3) conserved
Pf6N2E2_5261 -2.3 -1.1 FIG00956983: hypothetical protein compare
Pf6N2E2_5150 -2.3 -6.3 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_2984 -2.3 -2.2 LysR family transcriptional regulator PA3398 compare
Pf6N2E2_1776 -2.3 -2.4 Chemotaxis protein CheD compare
Pf6N2E2_5728 -2.3 -4.5 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4272 -2.3 -2.7 putative membrane protein compare
Pf6N2E2_5153 -2.3 -5.6 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_4187 -2.3 -8.7 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5679 -2.3 -4.2 hypothetical protein compare
Pf6N2E2_3261 -2.3 -9.0 hypothetical protein compare
Pf6N2E2_2065 -2.3 -2.1 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_2646 -2.3 -1.2 FIG00953416: hypothetical protein compare
Pf6N2E2_3820 -2.2 -2.2 hypothetical protein compare
Pf6N2E2_5014 -2.2 -0.7 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_760 -2.2 -10.4 Na+/H+ antiporter NhaB compare
Pf6N2E2_2605 -2.2 -14.0 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) compare
Pf6N2E2_5676 -2.2 -4.1 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_4052 -2.2 -1.2 FIG00955481: hypothetical protein compare
Pf6N2E2_1239 -2.2 -7.1 Putative TEGT family carrier/transport protein compare
Pf6N2E2_2261 -2.2 -6.0 VacJ-like lipoprotein precursor compare
Pf6N2E2_3826 -2.2 -5.1 Nitrogen regulation protein NR(I) compare
Pf6N2E2_3477 -2.1 -1.0 2-Oxobutyrate oxidase, putative compare
Pf6N2E2_1718 -2.1 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_5243 -2.0 -1.6 hypothetical protein compare
Pf6N2E2_2510 -2.0 -2.3 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_4057 -2.0 -0.6 lipoprotein, putative compare
Pf6N2E2_3933 -2.0 -7.8 D-2-hydroxyglutarate dehydrogenase compare
Pf6N2E2_5188 -2.0 -2.9 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2753 -1.9 -1.8 HtrA protease/chaperone protein compare
Pf6N2E2_3901 -1.9 -2.2 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) compare
Pf6N2E2_4071 -1.9 -3.8 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_5342 -1.9 -1.3 21 kDa hemolysin precursor compare
Pf6N2E2_4414 -1.9 -1.3 FIG00953808: hypothetical protein compare
Pf6N2E2_1113 -1.9 -1.2 Transcriptional regulator, TetR family compare
Pf6N2E2_5178 -1.9 -2.6 CDP-diacylglycerol--serine O-phosphatidyltransferase (EC 2.7.8.8) compare
Pf6N2E2_1287 -1.9 -2.4 Mobile element protein compare
Pf6N2E2_3941 -1.9 -1.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2586 -1.9 -2.2 Hpt domain protein compare
Pf6N2E2_3062 -1.8 -4.0 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2281 -1.8 -2.9 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_4797 -1.8 -1.1 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2384 -1.8 -2.6 CmpX compare
Pf6N2E2_5536 -1.8 -1.1 Holliday junction DNA helicase RuvA compare
Pf6N2E2_288 -1.8 -1.1 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_2526 -1.8 -4.4 Similar to phosphoglycolate phosphatase, clustered with ubiquinone biosynthesis SAM-dependent O-methyltransferase compare
Pf6N2E2_2823 -1.8 -5.0 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_133 -1.8 -2.5 hypothetical protein compare
Pf6N2E2_5328 -1.8 -4.5 FIG00958649: hypothetical protein compare
Pf6N2E2_5667 -1.8 -5.9 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_4162 -1.7 -3.4 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_4599 -1.7 -3.0 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_4803 -1.7 -1.1 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_5579 -1.7 -6.5 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4764 -1.7 -4.6 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_1920 -1.7 -1.6 Rubredoxin compare
Pf6N2E2_895 -1.7 -4.5 Transcriptional regulator, HxlR family compare
Pf6N2E2_1435 -1.7 -2.3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; sulfonate monooxygenase compare
Pf6N2E2_4759 -1.7 -8.1 Biotin synthase (EC 2.8.1.6) compare
Pf6N2E2_3770 -1.7 -1.1 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_2022 -1.7 -2.2 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_1797 -1.7 -1.7 Transcriptional regulator compare
Pf6N2E2_178 -1.7 -0.5 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_4763 -1.7 -6.7 Biotin synthesis protein BioC compare
Pf6N2E2_3666 -1.7 -2.8 InaA protein compare
Pf6N2E2_1676 -1.7 -2.3 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_5575 -1.6 -1.9 Glycerol uptake facilitator protein compare
Pf6N2E2_5991 -1.6 -3.4 proteinase inhibitor compare
Pf6N2E2_4394 -1.6 -4.2 Putrescine utilization regulator compare
Pf6N2E2_5001 -1.6 -1.1 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_2899 -1.6 -3.5 NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.12) compare
Pf6N2E2_2133 -1.6 -5.2 Putative sulfate permease compare
Pf6N2E2_1029 -1.6 -3.9 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases compare
Pf6N2E2_5961 -1.6 -5.9 Transcriptional regulator, TetR family compare
Pf6N2E2_1876 -1.6 -1.7 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) compare
Pf6N2E2_237 -1.6 -2.3 hypothetical protein compare
Pf6N2E2_3665 -1.6 -1.1 serine/threonine protein kinase compare
Pf6N2E2_5156 -1.6 -1.5 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_4476 -1.6 -3.6 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_2013 -1.6 -0.8 hypothetical protein compare
Pf6N2E2_2513 -1.6 -2.0 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_4517 -1.6 -4.0 Putrescine transport system permease protein PotI (TC 3.A.1.11.2) compare
Pf6N2E2_2852 -1.6 -7.2 GGDEF domain/EAL domain protein compare
Pf6N2E2_2606 -1.6 -7.3 hypothetical protein compare
Pf6N2E2_3260 -1.6 -3.3 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_2264 -1.5 -3.7 NADPH dependent preQ0 reductase (EC 1.7.1.13) compare
Pf6N2E2_5049 -1.5 -2.3 acetyltransferase, GNAT family compare
Pf6N2E2_3060 -1.5 -2.9 Outer membrane protein H precursor compare
Pf6N2E2_1391 -1.5 -2.1 DNA-binding response regulator, LuxR family compare
Pf6N2E2_4989 -1.5 -3.2 LrgA-associated membrane protein LrgB compare
Pf6N2E2_3305 -1.5 -3.6 hypothetical protein compare
Pf6N2E2_1450 -1.5 -1.9 FIG00960438: hypothetical protein compare
Pf6N2E2_3346 -1.5 -4.7 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) compare
Pf6N2E2_4049 -1.5 -7.0 Glycine cleavage system transcriptional activator compare
Pf6N2E2_2277 -1.5 -2.0 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3696 -1.5 -0.8 hypothetical protein compare
Pf6N2E2_5258 -1.5 -5.8 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_3786 -1.5 -9.7 Twin-arginine translocation protein TatC compare
Pf6N2E2_5252 -1.5 -3.8 FIG00956396: hypothetical protein compare
Pf6N2E2_4273 -1.5 -6.5 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_3938 -1.4 -8.7 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_4075 -1.4 -5.5 Phosphate ABC transporter, periplasmic phosphate-binding protein PstS (TC 3.A.1.7.1) compare
Pf6N2E2_3258 -1.4 -3.2 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_5534 -1.4 -2.6 FIG000859: hypothetical protein YebC compare
Pf6N2E2_2574 -1.4 -1.5 Flagellar synthesis regulator FleN compare
Pf6N2E2_2352 -1.4 -2.4 Type III secretion bridge between inner and outermembrane lipoprotein (YscJ,HrcJ,EscJ, PscJ) compare
Pf6N2E2_3277 -1.4 -1.9 FagA protein compare
Pf6N2E2_4601 -1.4 -1.3 Hypothetical protein YggS, proline synthase co-transcribed bacterial homolog PROSC compare
Pf6N2E2_2824 -1.4 -5.8 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_1211 -1.4 -1.4 Lactoylglutathione lyase compare
Pf6N2E2_3134 -1.4 -0.9 hypothetical protein compare
Pf6N2E2_3840 -1.4 -2.5 FIG00956267: hypothetical protein compare
Pf6N2E2_2675 -1.4 -0.9 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_2072 -1.3 -1.6 hypothetical protein compare
Pf6N2E2_2267 -1.3 -2.8 Osmosensitive K+ channel histidine kinase KdpD (EC 2.7.3.-) compare
Pf6N2E2_1545 -1.3 -2.8 N-carbamoylputrescine amidase (EC 3.5.1.53) compare
Pf6N2E2_1056 -1.3 -0.6 Quinone oxidoreductase (EC 1.6.5.5) compare
Pf6N2E2_2825 -1.3 -3.9 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_2123 -1.3 -2.7 hypothetical protein compare
Pf6N2E2_2885 -1.3 -4.1 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_3095 -1.3 -0.4 hypothetical protein compare
Pf6N2E2_4372 -1.3 -2.3 FIG00460773: hypothetical protein compare
Pf6N2E2_88 -1.3 -1.2 hypothetical protein compare
Pf6N2E2_251 -1.3 -3.5 transcriptional regulator compare
Pf6N2E2_5669 -1.3 -5.5 Succinylarginine dihydrolase (EC 3.5.3.23) compare
Pf6N2E2_4073 -1.3 -5.4 Phosphate transport system permease protein PstA (TC 3.A.1.7.1) compare


Specific Phenotypes

For 13 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Nickel (II) chloride hexahydrate across organisms