Experiment set11IT010 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with Zinc sulfate heptahydrate 0.032 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_4597 -5.2 -9.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4187 -5.1 -9.5 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_4826 -5.0 -9.0 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_64 -4.9 -5.2 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_71 -4.9 -7.5 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3948 -4.8 -14.5 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3661 -4.6 -11.1 hypothetical protein compare
Pf6N2E2_3782 -4.4 -6.0 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3839 -4.4 -4.3 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_4596 -4.3 -10.4 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4825 -4.3 -9.9 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3383 -4.2 -7.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4473 -4.1 -12.8 HlyD family secretion protein compare
Pf6N2E2_3783 -4.0 -8.1 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3630 -4.0 -8.4 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2822 -4.0 -7.3 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_3842 -4.0 -5.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_5720 -3.9 -14.1 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_3381 -3.9 -8.7 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_5176 -3.9 -8.6 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_4472 -3.9 -16.2 ABC-type multidrug transport system, permease component compare
Pf6N2E2_4048 -3.9 -10.1 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_2073 -3.9 -9.6 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3610 -3.9 -6.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2323 -3.9 -3.7 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_2022 -3.8 -4.5 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_3382 -3.8 -9.6 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3461 -3.7 -2.5 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2574 -3.7 -3.6 Flagellar synthesis regulator FleN compare
Pf6N2E2_5679 -3.7 -5.0 hypothetical protein compare
Pf6N2E2_5014 -3.7 -1.6 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3264 -3.7 -6.0 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3751 -3.6 -13.7 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_4071 -3.6 -5.0 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_2752 -3.6 -5.5 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_5175 -3.6 -10.5 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4047 -3.6 -7.5 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3253 -3.5 -7.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4564 -3.5 -12.1 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_4278 -3.4 -13.2 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3752 -3.4 -17.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_4279 -3.3 -13.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_5177 -3.3 -8.8 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4987 -3.3 -1.4 MaoC-like domain protein compare
Pf6N2E2_2218 -3.3 -4.9 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_3645 -3.3 -14.6 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_3841 -3.2 -4.4 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_4471 -3.1 -10.4 ABC-type multidrug transport system, permease component compare
Pf6N2E2_2261 -3.1 -4.2 VacJ-like lipoprotein precursor compare
Pf6N2E2_5950 -3.0 -5.3 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2513 -3.0 -5.6 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_2938 -3.0 -6.3 Outer membrane lipoprotein compare
Pf6N2E2_3037 -3.0 -12.5 RNA polymerase sigma factor RpoS compare
Pf6N2E2_77 -2.9 -4.1 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_2217 -2.9 -6.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_5006 -2.8 -7.6 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4678 -2.8 -1.7 hypothetical protein compare
Pf6N2E2_2074 -2.7 -2.4 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3252 -2.7 -8.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3380 -2.7 -8.5 L-lactate permease compare
Pf6N2E2_3932 -2.7 -4.1 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3940 -2.7 -10.2 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_66 -2.6 -8.0 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3384 -2.6 -4.0 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_3351 -2.6 -5.6 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_302 -2.5 -7.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2282 -2.5 -3.7 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_3258 -2.5 -2.4 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_4277 -2.5 -11.5 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_3908 -2.5 -4.0 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5780 -2.4 -8.2 Periplasmic protease compare
Pf6N2E2_4638 -2.4 -3.2 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3170 -2.4 -7.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2510 -2.4 -5.8 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3183 -2.3 -3.0 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_2258 -2.3 -10.0 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_63 -2.2 -4.4 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_6140 -2.2 -0.9 Large Subunit Ribosomal RNA; lsuRNA; LSU rRNA compare
Pf6N2E2_3062 -2.1 -3.9 Membrane-associated zinc metalloprotease compare
Pf6N2E2_3260 -2.1 -3.6 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_5728 -2.1 -5.3 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3248 -2.0 -3.0 Probable transmembrane protein compare
Pf6N2E2_1981 -2.0 -2.5 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_2681 -1.9 -2.8 3-phosphoglycerate kinase compare
Pf6N2E2_5666 -1.9 -7.4 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_3257 -1.9 -2.2 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3095 -1.9 -1.8 hypothetical protein compare
Pf6N2E2_2277 -1.9 -3.0 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3251 -1.9 -8.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_5160 -1.8 -1.5 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2514 -1.7 -4.2 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_3665 -1.7 -1.8 serine/threonine protein kinase compare
Pf6N2E2_987 -1.7 -2.4 hypothetical protein compare
Pf6N2E2_2117 -1.7 -10.6 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_3941 -1.7 -1.9 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_5711 -1.7 -6.0 tRNA(Cytosine32)-2-thiocytidine synthetase compare
Pf6N2E2_4360 -1.7 -8.9 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_5342 -1.7 -2.6 21 kDa hemolysin precursor compare
Pf6N2E2_5705 -1.6 -3.7 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_2286 -1.6 -1.9 FIG00953287: hypothetical protein compare
Pf6N2E2_4611 -1.6 -2.9 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3876 -1.6 -3.6 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_4372 -1.6 -4.4 FIG00460773: hypothetical protein compare
Pf6N2E2_4422 -1.6 -1.9 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_4799 -1.5 -10.6 ycgB component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
Pf6N2E2_2465 -1.5 -4.6 Cys regulon transcriptional activator CysB compare
Pf6N2E2_3762 -1.5 -5.6 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_5536 -1.5 -1.4 Holliday junction DNA helicase RuvA compare
Pf6N2E2_4800 -1.5 -10.0 yeaH component of nitrogen-related signalling system yeaH (of yeaGH-ycgB) (from data) compare
Pf6N2E2_4416 -1.5 -2.1 Tyrosine recombinase XerC compare
Pf6N2E2_3763 -1.4 -1.9 hypothetical protein compare
Pf6N2E2_5667 -1.4 -5.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3663 -1.4 -7.8 Glycosyl transferase compare
Pf6N2E2_3847 -1.4 -3.3 FIG001341: Probable Fe(2+)-trafficking protein YggX compare
Pf6N2E2_3270 -1.4 -4.5 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_4612 -1.4 -3.9 Glutathione synthetase (EC 6.3.2.3) compare
Pf6N2E2_5678 -1.4 -4.3 hypothetical protein compare
Pf6N2E2_3658 -1.4 -6.5 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_3505 -1.4 -1.4 Translation initiation factor SUI1-related protein compare
Pf6N2E2_3385 -1.4 -9.2 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing compare
Pf6N2E2_5520 -1.4 -5.5 Sensory box histidine kinase compare
Pf6N2E2_3659 -1.4 -5.1 Protein fixF compare
Pf6N2E2_2588 -1.4 -2.6 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3487 -1.3 -6.1 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_4614 -1.3 -3.7 twitching motility protein PilH compare
Pf6N2E2_3664 -1.3 -6.1 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_4801 -1.3 -10.0 yeaG component of nitrogen-related signalling system (of yeaGH-ycgB) (from data) compare
Pf6N2E2_1758 -1.3 -2.4 Transcriptional regulator, MarR family compare
Pf6N2E2_5257 -1.3 -6.8 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4049 -1.3 -6.1 Glycine cleavage system transcriptional activator compare
Pf6N2E2_3984 -1.3 -8.4 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_248 -1.3 -5.4 hypothetical protein compare
Pf6N2E2_5573 -1.3 -4.1 Glycerol-3-phosphate regulon repressor, DeoR family compare
Pf6N2E2_3738 -1.2 -3.1 General secretion pathway protein L compare
Pf6N2E2_5258 -1.2 -6.5 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4797 -1.2 -1.4 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_895 -1.2 -3.4 Transcriptional regulator, HxlR family compare
Pf6N2E2_5739 -1.2 -1.2 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_1606 -1.2 -3.8 Carboxynorspermidine decarboxylase, putative (EC 4.1.1.-) compare
Pf6N2E2_4710 -1.2 -1.6 hypothetical protein compare
Pf6N2E2_3300 -1.2 -2.8 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_2068 -1.2 -4.5 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_2746 -1.2 -3.8 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_4059 -1.2 -1.3 DNA-binding protein HU-alpha compare
Pf6N2E2_5665 -1.2 -4.9 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_4988 -1.2 -3.7 Antiholin-like protein LrgA compare
Pf6N2E2_3938 -1.2 -7.5 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3667 -1.2 -1.1 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_2189 -1.2 -4.3 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_5575 -1.2 -0.8 Glycerol uptake facilitator protein compare
Pf6N2E2_4305 -1.2 -1.2 FIG00959590: hypothetical protein compare
Pf6N2E2_3617 -1.2 -3.2 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_4824 -1.2 -3.8 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_2708 -1.2 -4.1 Lactam utilization protein LamB compare
Pf6N2E2_2534 -1.2 -3.5 Cell division protein BolA compare
Pf6N2E2_6045 -1.2 -1.4 hypothetical protein compare
Pf6N2E2_3869 -1.1 -6.0 Branched-chain amino acid transport protein AzlC compare
Pf6N2E2_2506 -1.1 -7.8 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_5647 -1.1 -4.2 Transcriptional regulator, TetR family compare
Pf6N2E2_3517 -1.1 -2.7 tRNA dihydrouridine synthase B (EC 1.-.-.-) compare
Pf6N2E2_170 -1.1 -1.7 lipoprotein, putative compare
Pf6N2E2_300 -1.1 -2.8 CrcB protein compare
Pf6N2E2_5825 -1.1 -3.3 FIG00958237: hypothetical protein compare
Pf6N2E2_2088 -1.1 -2.1 SOS-response repressor and protease LexA (EC 3.4.21.88) compare
Pf6N2E2_2503 -1.1 -1.8 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_1211 -1.1 -1.3 Lactoylglutathione lyase compare
Pf6N2E2_3612 -1.1 -1.9 HflK protein compare
Pf6N2E2_3344 -1.0 -2.6 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD compare
Pf6N2E2_4267 -1.0 -4.6 FIG00957502: hypothetical protein compare
Pf6N2E2_4989 -1.0 -3.7 LrgA-associated membrane protein LrgB compare
Pf6N2E2_4414 -1.0 -1.3 FIG00953808: hypothetical protein compare
Pf6N2E2_5579 -1.0 -3.6 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_4974 -1.0 -5.4 DedA protein compare
Pf6N2E2_4584 -1.0 -2.6 Cell division transporter, ATP-binding protein FtsE (TC 3.A.5.1.1) compare
Pf6N2E2_3134 -1.0 -1.1 hypothetical protein compare
Pf6N2E2_4476 -1.0 -3.5 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) compare
Pf6N2E2_4464 -1.0 -1.6 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases / CDP-6-deoxy-delta-3,4-glucoseen reductase-like compare
Pf6N2E2_2756 -1.0 -3.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_5955 -1.0 -3.2 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_5555 -0.9 -0.9 Cold shock protein CspA compare
Pf6N2E2_5207 -0.9 -2.3 hypothetical protein compare
Pf6N2E2_906 -0.9 -2.2 ISPpu14, transposase Orf2 compare
Pf6N2E2_3079 -0.9 -5.5 Cysteine desulfurase CsdA-CsdE (EC 2.8.1.7), main protein CsdA compare
Pf6N2E2_1932 -0.9 -2.4 Transcriptional regulator, IclR family compare
Pf6N2E2_5339 -0.9 -6.6 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_3840 -0.9 -2.7 FIG00956267: hypothetical protein compare
Pf6N2E2_3027 -0.9 -0.9 Baseplate assembly protein V compare
Pf6N2E2_5153 -0.9 -3.9 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2013 -0.9 -1.0 hypothetical protein compare
Pf6N2E2_600 -0.9 -1.6 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases compare
Pf6N2E2_1935 -0.9 -1.6 Enoyl-CoA hydratase (EC 4.2.1.17) compare
Pf6N2E2_1894 -0.9 -3.0 hypothetical protein compare
Pf6N2E2_5430 -0.9 -3.7 Transglycosylase, Slt family compare
Pf6N2E2_2795 -0.9 -1.7 putative exported protein compare
Pf6N2E2_4273 -0.9 -4.0 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_50 -0.9 -3.8 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_4162 -0.9 -3.1 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_1839 -0.9 -2.4 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase (EC 1.1.1.-) compare
Pf6N2E2_3081 -0.9 -3.1 HesA/MoeB/ThiF family protein related to EC-YgdL compare
Pf6N2E2_5425 -0.9 -1.4 hypothetical protein compare


Specific Phenotypes

For 4 genes in this experiment

For stress Zinc sulfate heptahydrate in Pseudomonas fluorescens FW300-N2E2

For stress Zinc sulfate heptahydrate across organisms