Experiment set11IT009 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with Zinc sulfate heptahydrate 0.016 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3842 -5.9 -4.1 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4597 -5.8 -7.9 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_64 -5.8 -5.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3782 -5.5 -3.8 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_71 -5.3 -6.3 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3383 -5.2 -7.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3630 -5.2 -7.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5176 -4.9 -3.4 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_5177 -4.6 -12.9 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_5720 -4.5 -12.9 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_4048 -4.4 -9.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_3381 -4.4 -11.3 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_3610 -4.3 -5.6 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_3751 -4.3 -14.1 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_3783 -4.2 -5.9 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_2074 -4.2 -2.5 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4047 -4.1 -6.8 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4826 -4.1 -8.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3661 -4.0 -10.2 hypothetical protein compare
Pf6N2E2_66 -4.0 -10.9 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_4279 -3.9 -14.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_2022 -3.9 -4.6 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_4564 -3.8 -9.8 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_5175 -3.8 -8.9 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_77 -3.8 -4.5 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3752 -3.8 -19.5 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3248 -3.7 -4.1 Probable transmembrane protein compare
Pf6N2E2_2323 -3.7 -3.6 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_2073 -3.7 -9.2 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3940 -3.7 -11.5 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_2510 -3.6 -6.4 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3382 -3.6 -8.7 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_2752 -3.6 -4.9 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_3932 -3.5 -5.8 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_4472 -3.5 -15.4 ABC-type multidrug transport system, permease component compare
Pf6N2E2_4825 -3.5 -7.6 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3252 -3.4 -9.0 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3253 -3.4 -7.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_4278 -3.4 -11.1 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_2822 -3.3 -8.4 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_4987 -3.2 -1.3 MaoC-like domain protein compare
Pf6N2E2_4596 -3.2 -9.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3839 -3.1 -5.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3384 -3.1 -5.4 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_4473 -3.1 -8.7 HlyD family secretion protein compare
Pf6N2E2_5006 -3.0 -7.5 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_3645 -3.0 -10.6 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_2513 -3.0 -5.6 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_3380 -2.9 -7.4 L-lactate permease compare
Pf6N2E2_302 -2.9 -6.6 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_4471 -2.9 -8.9 ABC-type multidrug transport system, permease component compare
Pf6N2E2_4277 -2.8 -9.4 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4928 -2.8 -2.3 Permeases of the major facilitator superfamily compare
Pf6N2E2_2574 -2.8 -2.9 Flagellar synthesis regulator FleN compare
Pf6N2E2_4187 -2.7 -11.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_3170 -2.6 -7.3 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2261 -2.6 -4.8 VacJ-like lipoprotein precursor compare
Pf6N2E2_5666 -2.5 -9.0 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_5103 -2.5 -1.4 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_2465 -2.5 -4.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2413 -2.5 -3.2 FIG074102: hypothetical protein compare
Pf6N2E2_5679 -2.3 -5.8 hypothetical protein compare
Pf6N2E2_3264 -2.2 -7.2 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_63 -2.2 -5.2 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2753 -2.1 -3.1 HtrA protease/chaperone protein compare
Pf6N2E2_2218 -2.1 -4.6 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_4638 -2.1 -3.4 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_3325 -2.1 -2.9 ABC transporter, ATP-binding protein compare
Pf6N2E2_5014 -2.1 -1.2 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_3885 -2.1 -2.4 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_3841 -2.1 -4.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3659 -2.0 -8.0 Protein fixF compare
Pf6N2E2_4414 -2.0 -1.9 FIG00953808: hypothetical protein compare
Pf6N2E2_4416 -2.0 -2.3 Tyrosine recombinase XerC compare
Pf6N2E2_5242 -2.0 -1.9 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_4204 -2.0 -1.3 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_2217 -2.0 -5.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4611 -2.0 -2.9 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_3460 -2.0 -1.3 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_2277 -1.9 -2.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_3663 -1.9 -9.1 Glycosyl transferase compare
Pf6N2E2_5780 -1.9 -7.3 Periplasmic protease compare
Pf6N2E2_4372 -1.9 -5.0 FIG00460773: hypothetical protein compare
Pf6N2E2_5728 -1.9 -4.2 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_2281 -1.9 -2.4 Beta N-acetyl-glucosaminidase (EC 3.2.1.52) compare
Pf6N2E2_4579 -1.9 -1.7 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_3251 -1.8 -7.0 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_1162 -1.8 -2.6 Transmembrane amino acid efflux protein compare
Pf6N2E2_2938 -1.8 -4.1 Outer membrane lipoprotein compare
Pf6N2E2_3666 -1.7 -2.8 InaA protein compare
Pf6N2E2_3948 -1.7 -10.0 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3258 -1.7 -2.7 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_1720 -1.7 -3.9 hypothetical protein compare
Pf6N2E2_3658 -1.7 -6.8 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_1806 -1.6 -1.5 hypothetical protein compare
Pf6N2E2_4273 -1.6 -6.1 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_5739 -1.6 -1.2 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_5667 -1.6 -7.1 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3664 -1.5 -7.2 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_5943 -1.5 -1.9 hypothetical protein compare
Pf6N2E2_2503 -1.5 -2.1 Glycosyl transferase, group 1 family protein compare
Pf6N2E2_4803 -1.5 -1.3 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_1981 -1.5 -1.9 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_827 -1.5 -2.1 probable dioxygenase compare
Pf6N2E2_3095 -1.5 -1.4 hypothetical protein compare
Pf6N2E2_3984 -1.5 -7.6 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_1116 -1.5 -2.6 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_2286 -1.4 -1.7 FIG00953287: hypothetical protein compare
Pf6N2E2_3908 -1.4 -4.1 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_5258 -1.4 -5.7 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_241 -1.4 -1.5 hypothetical protein compare
Pf6N2E2_5574 -1.4 -4.3 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_2756 -1.4 -4.5 RNA polymerase sigma-H factor AlgT compare
Pf6N2E2_3260 -1.4 -3.3 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_5520 -1.4 -5.5 Sensory box histidine kinase compare
Pf6N2E2_4548 -1.3 -1.7 hypothetical protein compare
Pf6N2E2_2282 -1.3 -2.8 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_50 -1.3 -5.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_1340 -1.3 -1.5 major pilin protein fimA compare
Pf6N2E2_2675 -1.3 -0.7 ATP-dependent RNA helicase SrmB compare
Pf6N2E2_3037 -1.3 -7.0 RNA polymerase sigma factor RpoS compare
Pf6N2E2_5647 -1.3 -3.7 Transcriptional regulator, TetR family compare
Pf6N2E2_3876 -1.2 -3.0 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_6065 -1.2 -2.5 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_5049 -1.2 -1.3 acetyltransferase, GNAT family compare
Pf6N2E2_3257 -1.2 -2.2 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3938 -1.2 -7.9 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_3183 -1.2 -1.9 Believed to be involved in assembly of Fe-S clusters compare
Pf6N2E2_1596 -1.2 -1.9 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_3786 -1.2 -5.9 Twin-arginine translocation protein TatC compare
Pf6N2E2_5339 -1.2 -7.7 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_4340 -1.2 -4.7 Outer membrane protein ImpK/VasF, OmpA/MotB domain compare
Pf6N2E2_953 -1.2 -2.5 FIG00958851: hypothetical protein compare
Pf6N2E2_84 -1.2 -2.2 hypothetical protein compare
Pf6N2E2_5676 -1.2 -3.5 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_5111 -1.2 -1.3 FKBP-type peptidyl-prolyl cis-trans isomerase SlpA (EC 5.2.1.8) compare
Pf6N2E2_2258 -1.2 -6.5 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5575 -1.2 -0.8 Glycerol uptake facilitator protein compare
Pf6N2E2_2506 -1.2 -7.1 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_971 -1.1 -1.5 hypothetical protein compare
Pf6N2E2_3612 -1.1 -2.0 HflK protein compare
Pf6N2E2_5153 -1.1 -4.3 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_420 -1.1 -0.8 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_5257 -1.1 -5.5 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_2010 -1.1 -1.6 hypothetical protein compare
Pf6N2E2_2080 -1.1 -1.1 hypothetical protein compare
Pf6N2E2_3770 -1.1 -1.3 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_4824 -1.1 -3.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_5155 -1.1 -2.8 Poly(A) polymerase (EC 2.7.7.19) compare
Pf6N2E2_3617 -1.1 -4.4 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_5150 -1.1 -3.4 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_3667 -1.1 -0.9 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3762 -1.1 -3.8 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_3255 -1.0 -2.4 YrbA protein compare
Pf6N2E2_2274 -1.0 -2.7 Soluble pyridine nucleotide transhydrogenase (EC 1.6.1.1) compare
Pf6N2E2_2139 -1.0 -1.5 Paraquat-inducible protein A compare
Pf6N2E2_5665 -1.0 -3.9 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_2284 -1.0 -2.3 Cell division inhibitor-related protein compare
Pf6N2E2_3385 -1.0 -5.9 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing compare
Pf6N2E2_5579 -1.0 -3.4 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_6047 -1.0 -1.7 hypothetical protein compare
Pf6N2E2_4365 -1.0 -3.4 Ribonuclease PH (EC 2.7.7.56) compare
Pf6N2E2_2746 -1.0 -3.3 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_70 -1.0 -2.3 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_1743 -1.0 -2.0 Putrescine transport ATP-binding protein PotA (TC 3.A.1.11.1) compare
Pf6N2E2_1014 -1.0 -0.8 Nitrate/nitrite transporter compare
Pf6N2E2_5950 -1.0 -2.8 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2318 -1.0 -7.4 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_1652 -1.0 -1.4 Transcriptional regulator, TetR family compare
Pf6N2E2_2518 -1.0 -2.1 Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19) compare
Pf6N2E2_5510 -0.9 -1.8 FIG00955324: hypothetical protein compare
Pf6N2E2_2870 -0.9 -2.0 Ribonuclease BN (EC 3.1.-.-) compare
Pf6N2E2_4025 -0.9 -1.0 hypothetical protein compare
Pf6N2E2_2681 -0.9 -1.7 3-phosphoglycerate kinase compare
Pf6N2E2_4071 -0.9 -2.6 Phosphate transport system regulatory protein PhoU compare
Pf6N2E2_3271 -0.9 -1.7 Phosphocarrier protein, nitrogen regulation associated compare
Pf6N2E2_1705 -0.9 -1.2 Branched-chain amino acid transport ATP-binding protein LivG (TC 3.A.1.4.1) compare
Pf6N2E2_2586 -0.9 -1.1 Hpt domain protein compare
Pf6N2E2_2350 -0.9 -2.7 Oxygen-regulated invasion protein OrgB compare
Pf6N2E2_4743 -0.9 -0.7 hypothetical protein compare
Pf6N2E2_3373 -0.9 -3.6 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare
Pf6N2E2_4145 -0.9 -2.1 ABC-type transport system involved in resistance to organic solvents, periplasmic component USSDB6C compare
Pf6N2E2_4162 -0.9 -2.8 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_2480 -0.9 -1.1 FIG00957636: hypothetical protein compare
Pf6N2E2_2201 -0.9 -3.7 Transmembrane regulator protein PrtR compare
Pf6N2E2_3270 -0.9 -3.0 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_1932 -0.9 -2.2 Transcriptional regulator, IclR family compare
Pf6N2E2_6088 -0.9 -2.8 hypothetical protein compare
Pf6N2E2_4360 -0.9 -5.0 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_5338 -0.9 -6.5 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_3840 -0.9 -1.9 FIG00956267: hypothetical protein compare
Pf6N2E2_927 -0.9 -2.1 (AJ250023) putative polyketide synthase compare
Pf6N2E2_3568 -0.9 -2.0 Unsaturated fatty acid biosythesis repressor FabR, TetR family compare
Pf6N2E2_3941 -0.9 -1.3 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2440 -0.9 -1.0 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_2459 -0.8 -1.4 Organic hydroperoxide resistance protein compare
Pf6N2E2_818 -0.8 -2.6 Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY compare
Pf6N2E2_2795 -0.8 -0.9 putative exported protein compare
Pf6N2E2_2509 -0.8 -0.9 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_2111 -0.8 -2.2 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit A (from data) compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens FW300-N2E2 in stress experiments

For stress Zinc sulfate heptahydrate across organisms