Experiment set11IT007 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2 defined with Zinc sulfate heptahydrate 0.016 mM

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_3630 -5.3 -7.3 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_64 -5.2 -4.6 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_4597 -4.8 -11.1 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_3751 -4.7 -16.5 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_5720 -4.5 -14.3 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_4048 -4.4 -10.4 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4825 -4.4 -10.1 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_71 -4.2 -8.0 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_3253 -4.2 -7.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3382 -4.0 -9.4 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_5176 -4.0 -8.5 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_3841 -4.0 -2.7 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3661 -4.0 -10.8 hypothetical protein compare
Pf6N2E2_3752 -3.9 -20.6 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_5177 -3.9 -8.5 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_3842 -3.9 -6.2 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_77 -3.8 -4.4 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_3381 -3.8 -7.9 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_2022 -3.7 -6.2 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_5175 -3.7 -10.8 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4596 -3.7 -10.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_66 -3.7 -10.2 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_3783 -3.7 -7.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_3839 -3.6 -5.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3610 -3.6 -5.5 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2073 -3.5 -10.7 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_3383 -3.5 -6.8 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_4564 -3.4 -8.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_2752 -3.3 -7.4 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_4278 -3.3 -14.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_4279 -3.3 -13.6 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_5006 -3.3 -8.1 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4047 -3.2 -7.4 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_4826 -3.2 -8.8 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_4473 -3.2 -10.7 HlyD family secretion protein compare
Pf6N2E2_4472 -3.2 -15.0 ABC-type multidrug transport system, permease component compare
Pf6N2E2_2513 -3.1 -6.4 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_63 -3.0 -4.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2822 -2.9 -7.7 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_3252 -2.9 -8.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3940 -2.8 -11.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_3264 -2.8 -5.7 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3932 -2.8 -5.3 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3384 -2.7 -4.8 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_302 -2.6 -5.8 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_3782 -2.6 -6.9 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_2277 -2.6 -2.2 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_2074 -2.6 -3.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_3645 -2.5 -8.7 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_2681 -2.5 -3.3 3-phosphoglycerate kinase compare
Pf6N2E2_4277 -2.5 -12.3 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4638 -2.5 -3.3 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_4187 -2.5 -10.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_2261 -2.5 -6.0 VacJ-like lipoprotein precursor compare
Pf6N2E2_5679 -2.4 -4.9 hypothetical protein compare
Pf6N2E2_4471 -2.4 -9.6 ABC-type multidrug transport system, permease component compare
Pf6N2E2_3248 -2.4 -5.8 Probable transmembrane protein compare
Pf6N2E2_3170 -2.3 -7.2 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_2938 -2.3 -5.6 Outer membrane lipoprotein compare
Pf6N2E2_3380 -2.3 -7.0 L-lactate permease compare
Pf6N2E2_5666 -2.2 -11.2 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_2574 -2.2 -2.4 Flagellar synthesis regulator FleN compare
Pf6N2E2_2510 -2.2 -4.6 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_4416 -2.2 -2.5 Tyrosine recombinase XerC compare
Pf6N2E2_2465 -2.2 -5.8 Cys regulon transcriptional activator CysB compare
Pf6N2E2_4372 -2.0 -5.3 FIG00460773: hypothetical protein compare
Pf6N2E2_4797 -2.0 -1.7 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase (EC 2.7.6.3) compare
Pf6N2E2_2323 -2.0 -2.1 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_5728 -1.9 -3.8 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_4928 -1.9 -2.6 Permeases of the major facilitator superfamily compare
Pf6N2E2_3251 -1.9 -9.7 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_3658 -1.8 -8.7 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_3663 -1.8 -8.8 Glycosyl transferase compare
Pf6N2E2_3257 -1.8 -2.6 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3258 -1.8 -3.2 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_4579 -1.7 -1.9 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_2753 -1.7 -3.1 HtrA protease/chaperone protein compare
Pf6N2E2_3461 -1.6 -1.8 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_3664 -1.6 -8.6 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_5780 -1.6 -6.4 Periplasmic protease compare
Pf6N2E2_5667 -1.6 -6.8 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3659 -1.6 -6.3 Protein fixF compare
Pf6N2E2_3941 -1.6 -2.5 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_2217 -1.5 -4.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_4803 -1.4 -1.3 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical (EC 3.6.1.41) compare
Pf6N2E2_1886 -1.4 -2.0 hypothetical protein compare
Pf6N2E2_3948 -1.4 -9.3 Lead, cadmium, zinc and mercury transporting ATPase (EC 3.6.3.3) (EC 3.6.3.5); Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2218 -1.4 -4.1 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2506 -1.4 -9.2 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_1981 -1.3 -1.8 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_4987 -1.3 -1.0 MaoC-like domain protein compare
Pf6N2E2_159 -1.3 -3.9 DNA damage resistance protein (from data) compare
Pf6N2E2_4369 -1.3 -2.0 Exodeoxyribonuclease III (EC 3.1.11.2) compare
Pf6N2E2_3300 -1.3 -2.6 Predicted D-glucarate or D-galactorate regulator, GntR family compare
Pf6N2E2_2258 -1.3 -7.7 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_3908 -1.3 -4.2 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_2286 -1.3 -2.4 FIG00953287: hypothetical protein compare
Pf6N2E2_3984 -1.3 -9.1 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_2514 -1.3 -2.7 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_3260 -1.2 -3.4 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_1169 -1.2 -2.1 TnpR protein compare
Pf6N2E2_288 -1.2 -1.1 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_3037 -1.2 -7.6 RNA polymerase sigma factor RpoS compare
Pf6N2E2_6164 -1.2 -1.1 tRNA-Val-TAC compare
Pf6N2E2_2588 -1.2 -2.9 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_3617 -1.2 -5.0 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_3085 -1.2 -1.9 FIG00954614: hypothetical protein compare
Pf6N2E2_4273 -1.2 -5.3 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_2189 -1.2 -4.7 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_4678 -1.2 -1.2 hypothetical protein compare
Pf6N2E2_4414 -1.2 -1.6 FIG00953808: hypothetical protein compare
Pf6N2E2_6082 -1.2 -3.7 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3876 -1.2 -3.2 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_2827 -1.1 -1.5 hypothetical protein compare
Pf6N2E2_50 -1.1 -6.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_895 -1.1 -3.9 Transcriptional regulator, HxlR family compare
Pf6N2E2_1875 -1.1 -2.2 Protoporphyrinogen oxidase (EC 1.3.3.4) compare
Pf6N2E2_5574 -1.1 -4.1 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_5258 -1.1 -5.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_1652 -1.1 -1.8 Transcriptional regulator, TetR family compare
Pf6N2E2_3667 -1.1 -1.3 Heptose kinase WapQ, eukaryotic type compare
Pf6N2E2_3826 -1.1 -4.4 Nitrogen regulation protein NR(I) compare
Pf6N2E2_6060 -1.1 -3.3 Propionate catabolism operon transcriptional regulator of GntR family [predicted] compare
Pf6N2E2_5579 -1.0 -3.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_476 -1.0 -2.7 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_5257 -1.0 -5.2 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_3938 -1.0 -7.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2017 -1.0 -2.9 DNA-binding protein compare
Pf6N2E2_4394 -1.0 -2.9 Putrescine utilization regulator compare
Pf6N2E2_5316 -1.0 -1.9 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_1932 -1.0 -2.6 Transcriptional regulator, IclR family compare
Pf6N2E2_58 -1.0 -1.7 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_5665 -1.0 -4.6 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_3786 -1.0 -5.6 Twin-arginine translocation protein TatC compare
Pf6N2E2_5252 -1.0 -2.2 FIG00956396: hypothetical protein compare
Pf6N2E2_3199 -1.0 -2.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase (EC 5.-.-.-) compare
Pf6N2E2_1696 -1.0 -2.2 Alkanesulfonates-binding protein compare
Pf6N2E2_5103 -1.0 -1.1 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_1435 -1.0 -2.3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; sulfonate monooxygenase compare
Pf6N2E2_70 -1.0 -2.8 tRNA pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_3833 -1.0 -3.6 hypothetical protein compare
Pf6N2E2_2003 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_3385 -0.9 -6.8 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing compare
Pf6N2E2_2746 -0.9 -3.4 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_300 -0.9 -2.4 CrcB protein compare
Pf6N2E2_5955 -0.9 -3.2 Aminodeoxychorismate lyase (EC 4.1.3.38) compare
Pf6N2E2_3947 -0.9 -2.2 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_2010 -0.9 -1.1 hypothetical protein compare
Pf6N2E2_3283 -0.9 -2.5 Cytoplasmic axial filament protein CafA and Ribonuclease G (EC 3.1.4.-) compare
Pf6N2E2_5950 -0.9 -2.3 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_434 -0.9 -1.4 hypothetical protein compare
Pf6N2E2_2117 -0.9 -6.3 1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18) compare
Pf6N2E2_2340 -0.9 -2.7 Transcriptional regulator, GntR family compare
Pf6N2E2_3763 -0.9 -1.5 hypothetical protein compare
Pf6N2E2_5704 -0.9 -2.4 Transcriptional regulatory protein PhoP compare
Pf6N2E2_5508 -0.9 -1.3 Formyltetrahydrofolate deformylase (EC 3.5.1.10) compare
Pf6N2E2_3270 -0.8 -3.1 Hypothetical ATP-binding protein UPF0042, contains P-loop compare
Pf6N2E2_579 -0.8 -1.9 FIG00962753: hypothetical protein compare
Pf6N2E2_2072 -0.8 -1.6 hypothetical protein compare
Pf6N2E2_5150 -0.8 -3.0 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_529 -0.8 -4.0 FIG00954439: hypothetical protein compare
Pf6N2E2_5245 -0.8 -4.1 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_3460 -0.8 -0.9 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_3134 -0.8 -1.1 hypothetical protein compare
Pf6N2E2_3825 -0.8 -2.2 Nitrogen regulation protein NtrB (EC 2.7.13.3) compare
Pf6N2E2_922 -0.8 -2.3 FIG00794167: hypothetical protein compare
Pf6N2E2_3666 -0.8 -1.9 InaA protein compare
Pf6N2E2_5520 -0.8 -3.5 Sensory box histidine kinase compare
Pf6N2E2_841 -0.8 -1.9 hypothetical protein compare
Pf6N2E2_4614 -0.8 -2.1 twitching motility protein PilH compare
Pf6N2E2_5062 -0.8 -2.8 3-dehydroquinate dehydratase II (EC 4.2.1.10) compare
Pf6N2E2_238 -0.8 -1.7 hypothetical protein compare
Pf6N2E2_1958 -0.8 -2.5 Predicted dinucleotide-binding enzymes compare
Pf6N2E2_2509 -0.8 -1.4 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_3899 -0.8 -4.3 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_51 -0.8 -4.3 hypothetical protein compare
Pf6N2E2_5523 -0.8 -2.3 Small-conductance mechanosensitive channel compare
Pf6N2E2_2285 -0.8 -1.0 FIG00954079: hypothetical protein compare
Pf6N2E2_4360 -0.8 -4.8 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_2500 -0.8 -2.4 Putative membrane protein compare
Pf6N2E2_4298 -0.8 -2.2 Uncharacterized protein ImpB compare
Pf6N2E2_3942 -0.8 -5.1 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_3255 -0.8 -2.4 YrbA protein compare
Pf6N2E2_5331 -0.8 -3.0 ATPase, AFG1 family compare
Pf6N2E2_5160 -0.8 -0.9 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_3062 -0.8 -2.2 Membrane-associated zinc metalloprotease compare
Pf6N2E2_2794 -0.8 -1.7 putative membrane protein compare
Pf6N2E2_3952 -0.7 -2.7 putative RecF protein compare
Pf6N2E2_2318 -0.7 -5.9 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_2068 -0.7 -3.1 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_3516 -0.7 -2.0 Probable transmembrane protein compare
Pf6N2E2_4162 -0.7 -2.2 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_1469 -0.7 -2.7 NAD-dependent formate dehydrogenase gamma subunit compare
Pf6N2E2_2384 -0.7 -1.5 CmpX compare
Pf6N2E2_4824 -0.7 -2.5 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_82 -0.7 -1.7 hypothetical protein compare
Pf6N2E2_2312 -0.7 -1.7 Cytochrome c oxidase subunit CcoQ (EC 1.9.3.1) compare
Pf6N2E2_5339 -0.7 -5.0 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_1759 -0.7 -2.1 uncharacterized domain 1 compare
Pf6N2E2_5338 -0.7 -6.1 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens FW300-N2E2 in stress experiments

For stress Zinc sulfate heptahydrate across organisms