Experiment set11IT006 for Pseudomonas fluorescens FW300-N2E2

Compare to:

RCH2_defined

200 most important genes:

  gene name fitness t score description  
Pf6N2E2_64 -7.7 -5.3 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) compare
Pf6N2E2_3253 -5.2 -7.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Pf6N2E2_3839 -4.9 -4.8 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Pf6N2E2_3630 -4.9 -8.7 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_4597 -4.8 -11.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_4047 -4.8 -4.7 Tryptophan synthase alpha chain (EC 4.2.1.20) compare
Pf6N2E2_3782 -4.8 -6.5 Phosphoribosyl-AMP cyclohydrolase (EC 3.5.4.19) compare
Pf6N2E2_3751 -4.7 -16.9 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) compare
Pf6N2E2_77 -4.7 -5.5 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) compare
Pf6N2E2_5176 -4.6 -7.0 Acetolactate synthase small subunit (EC 2.2.1.6) compare
Pf6N2E2_71 -4.6 -8.2 Phosphoribosylanthranilate isomerase (EC 5.3.1.24) compare
Pf6N2E2_4596 -4.5 -11.6 Homoserine O-acetyltransferase (EC 2.3.1.31) compare
Pf6N2E2_2022 -4.5 -3.1 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_3381 -4.5 -11.4 Predicted L-lactate dehydrogenase, Fe-S oxidoreductase subunit YkgE compare
Pf6N2E2_5006 -4.5 -7.4 Muramoyltetrapeptide carboxypeptidase (EC 3.4.17.13) compare
Pf6N2E2_4279 -4.4 -16.1 Pyruvate carboxyl transferase subunit B (EC 6.4.1.1) compare
Pf6N2E2_3752 -4.4 -21.7 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) compare
Pf6N2E2_3783 -4.4 -8.8 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Pf6N2E2_5720 -4.3 -14.1 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_4048 -4.3 -9.5 Tryptophan synthase beta chain (EC 4.2.1.20) compare
Pf6N2E2_4825 -4.2 -11.1 Anthranilate phosphoribosyltransferase (EC 2.4.2.18) compare
Pf6N2E2_3252 -4.1 -10.8 Histidinol dehydrogenase (EC 1.1.1.23) compare
Pf6N2E2_3248 -3.9 -4.7 Probable transmembrane protein compare
Pf6N2E2_3461 -3.9 -2.7 Exodeoxyribonuclease V gamma chain (EC 3.1.11.5) compare
Pf6N2E2_2073 -3.9 -11.1 Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) compare
Pf6N2E2_5177 -3.9 -10.6 Ketol-acid reductoisomerase (EC 1.1.1.86) compare
Pf6N2E2_4826 -3.8 -9.9 Indole-3-glycerol phosphate synthase (EC 4.1.1.48) compare
Pf6N2E2_3932 -3.8 -4.5 D-3-phosphoglycerate dehydrogenase (EC 1.1.1.95) compare
Pf6N2E2_3382 -3.8 -9.1 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3383 -3.8 -9.0 Predicted L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit YkgF compare
Pf6N2E2_3661 -3.7 -10.4 hypothetical protein compare
Pf6N2E2_3645 -3.7 -10.7 Type I secretion outer membrane protein, TolC precursor compare
Pf6N2E2_3384 -3.7 -4.8 Predicted L-lactate dehydrogenase, hypothetical protein subunit YkgG compare
Pf6N2E2_4638 -3.6 -2.5 5,10-methylenetetrahydrofolate reductase (EC 1.5.1.20) compare
Pf6N2E2_66 -3.6 -10.1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) compare
Pf6N2E2_2752 -3.6 -6.5 Exported zinc metalloprotease YfgC precursor compare
Pf6N2E2_4473 -3.6 -13.1 HlyD family secretion protein compare
Pf6N2E2_3842 -3.6 -6.8 Imidazoleglycerol-phosphate dehydratase (EC 4.2.1.19) compare
Pf6N2E2_4472 -3.5 -15.6 ABC-type multidrug transport system, permease component compare
Pf6N2E2_5175 -3.5 -12.1 Acetolactate synthase large subunit (EC 2.2.1.6) compare
Pf6N2E2_4564 -3.4 -8.7 Dihydroxy-acid dehydratase (EC 4.2.1.9) compare
Pf6N2E2_3841 -3.1 -5.5 Imidazole glycerol phosphate synthase amidotransferase subunit (EC 2.4.2.-) compare
Pf6N2E2_3264 -3.1 -7.6 Uncharacterized protein YrbK clustered with lipopolysaccharide transporters compare
Pf6N2E2_3940 -3.0 -10.0 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_5666 -3.0 -9.7 Arginine N-succinyltransferase, alpha subunit (EC 2.3.1.109) compare
Pf6N2E2_4278 -2.9 -12.6 Pyruvate carboxyl transferase subunit A (EC 6.4.1.1) compare
Pf6N2E2_3610 -2.9 -4.0 ATP phosphoribosyltransferase regulatory subunit (EC 2.4.2.17) compare
Pf6N2E2_2277 -2.9 -3.8 NADPH-dependent glyceraldehyde-3-phosphate dehydrogenase (EC 1.2.1.13) compare
Pf6N2E2_302 -2.9 -7.1 Siroheme synthase / Precorrin-2 oxidase (EC 1.3.1.76) / Sirohydrochlorin ferrochelatase (EC 4.99.1.4) / Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) compare
Pf6N2E2_2753 -2.9 -4.2 HtrA protease/chaperone protein compare
Pf6N2E2_4277 -2.8 -10.8 LysR family transcriptional regulator PA5437 compare
Pf6N2E2_4187 -2.8 -14.8 Lipid A biosynthesis lauroyl acyltransferase (EC 2.3.1.-) compare
Pf6N2E2_63 -2.8 -4.1 3-isopropylmalate dehydratase large subunit (EC 4.2.1.33) compare
Pf6N2E2_2822 -2.8 -9.2 Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family compare
Pf6N2E2_3380 -2.7 -8.5 L-lactate permease compare
Pf6N2E2_2465 -2.7 -6.5 Cys regulon transcriptional activator CysB compare
Pf6N2E2_2513 -2.5 -6.0 UDP-glucose dehydrogenase (EC 1.1.1.22) compare
Pf6N2E2_5014 -2.5 -1.5 Apolipoprotein N-acyltransferase (EC 2.3.1.-) / Copper homeostasis protein CutE compare
Pf6N2E2_4471 -2.5 -8.1 ABC-type multidrug transport system, permease component compare
Pf6N2E2_5728 -2.3 -4.9 Phosphoribosylglycinamide formyltransferase (EC 2.1.2.2) compare
Pf6N2E2_3251 -2.3 -11.3 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Pf6N2E2_4579 -2.2 -2.5 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_3170 -2.2 -6.8 2-isopropylmalate synthase (EC 2.3.3.13) compare
Pf6N2E2_4372 -2.2 -6.2 FIG00460773: hypothetical protein compare
Pf6N2E2_3460 -2.2 -1.5 Exodeoxyribonuclease V beta chain (EC 3.1.11.5) compare
Pf6N2E2_1981 -2.2 -2.6 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_2261 -2.2 -6.3 VacJ-like lipoprotein precursor compare
Pf6N2E2_2217 -2.1 -6.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
Pf6N2E2_178 -2.1 -1.5 Phenylalanyl-tRNA synthetase beta chain (EC 6.1.1.20) compare
Pf6N2E2_5160 -2.0 -1.5 C4-type zinc finger protein, DksA/TraR family compare
Pf6N2E2_2681 -2.0 -2.6 3-phosphoglycerate kinase compare
Pf6N2E2_2510 -2.0 -4.1 Lipid carrier : UDP-N-acetylgalactosaminyltransferase (EC 2.4.1.-) / Alpha-1,3-N-acetylgalactosamine transferase PglA (EC 2.4.1.-); Putative glycosyltransferase compare
Pf6N2E2_3663 -1.9 -10.2 Glycosyl transferase compare
Pf6N2E2_3257 -1.9 -2.7 Uncharacterized ABC transporter, auxiliary component YrbC compare
Pf6N2E2_3258 -1.8 -3.4 Uncharacterized ABC transporter, periplasmic component YrbD compare
Pf6N2E2_3659 -1.8 -8.7 Protein fixF compare
Pf6N2E2_4416 -1.8 -2.6 Tyrosine recombinase XerC compare
Pf6N2E2_5679 -1.8 -4.1 hypothetical protein compare
Pf6N2E2_3260 -1.7 -4.0 Uncharacterized ABC transporter, ATP-binding protein YrbF compare
Pf6N2E2_3664 -1.7 -8.2 Carbamoyltransferase in large core OS assembly cluster compare
Pf6N2E2_2514 -1.7 -4.4 regulator of length of O-antigen component of lipopolysaccharide chains compare
Pf6N2E2_5667 -1.7 -7.1 Arginine N-succinyltransferase (EC 2.3.1.109) compare
Pf6N2E2_3770 -1.6 -2.4 ATP-dependent hsl protease ATP-binding subunit HslU compare
Pf6N2E2_2218 -1.6 -4.0 ATP-dependent Clp protease proteolytic subunit (EC 3.4.21.92) compare
Pf6N2E2_2938 -1.6 -4.7 Outer membrane lipoprotein compare
Pf6N2E2_3658 -1.5 -8.0 Lipid A core - O-antigen ligase and related enzymes compare
Pf6N2E2_5103 -1.5 -1.5 Glutamate 5-kinase (EC 2.7.2.11) / RNA-binding C-terminal domain PUA compare
Pf6N2E2_50 -1.5 -7.7 Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57) compare
Pf6N2E2_5780 -1.5 -6.7 Periplasmic protease compare
Pf6N2E2_2574 -1.5 -2.3 Flagellar synthesis regulator FleN compare
Pf6N2E2_4414 -1.5 -1.9 FIG00953808: hypothetical protein compare
Pf6N2E2_3666 -1.5 -2.9 InaA protein compare
Pf6N2E2_2282 -1.4 -3.2 Predicted transcriptional regulator for fatty acid degradation FadQ, TetR family compare
Pf6N2E2_3984 -1.4 -9.7 T1SS associated transglutaminase-like cysteine proteinase LapP compare
Pf6N2E2_3095 -1.4 -1.7 hypothetical protein compare
Pf6N2E2_3826 -1.4 -5.4 Nitrogen regulation protein NR(I) compare
Pf6N2E2_5575 -1.3 -0.9 Glycerol uptake facilitator protein compare
Pf6N2E2_3938 -1.3 -9.3 Threonine dehydratase biosynthetic (EC 4.3.1.19) compare
Pf6N2E2_2506 -1.3 -9.4 nucleotide sugar epimerase/dehydratase WbpM compare
Pf6N2E2_4273 -1.3 -5.9 ATP-dependent DNA helicase UvrD/PcrA compare
Pf6N2E2_2074 -1.3 -1.2 required for sulfate utilization, putative electron transport protein for sulfite reductase (from data) compare
Pf6N2E2_4025 -1.3 -2.0 hypothetical protein compare
Pf6N2E2_3062 -1.3 -3.3 Membrane-associated zinc metalloprotease compare
Pf6N2E2_1162 -1.3 -2.8 Transmembrane amino acid efflux protein compare
Pf6N2E2_2323 -1.2 -1.3 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_5316 -1.2 -1.7 Periplasmic thiol:disulfide oxidoreductase DsbB, required for DsbA reoxidation compare
Pf6N2E2_4418 -1.1 -0.8 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_2588 -1.1 -2.3 Anti-sigma F factor antagonist (spoIIAA-2); Anti-sigma B factor antagonist RsbV compare
Pf6N2E2_2189 -1.1 -4.0 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_3037 -1.1 -7.4 RNA polymerase sigma factor RpoS compare
Pf6N2E2_3617 -1.1 -4.0 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) compare
Pf6N2E2_4611 -1.1 -2.8 Ferric siderophore transport system, periplasmic binding protein TonB compare
Pf6N2E2_5520 -1.1 -4.4 Sensory box histidine kinase compare
Pf6N2E2_5665 -1.1 -4.5 Succinylornithine transaminase (EC 2.6.1.81) compare
Pf6N2E2_5579 -1.1 -3.7 Ornithine carbamoyltransferase (EC 2.1.3.3) compare
Pf6N2E2_3941 -1.1 -1.8 Adenosine (5')-pentaphospho-(5'')-adenosine pyrophosphohydrolase (EC 3.6.1.-) compare
Pf6N2E2_3899 -1.1 -6.1 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_5527 -1.1 -1.8 Cold shock protein CspC compare
Pf6N2E2_4943 -1.1 -3.5 PspA/IM30 family protein compare
Pf6N2E2_3942 -1.1 -7.3 FIG001592: Phosphocarrier protein kinase/phosphorylase, nitrogen regulation associated compare
Pf6N2E2_2318 -1.1 -8.1 Type cbb3 cytochrome oxidase biogenesis protein CcoI; Copper-translocating P-type ATPase (EC 3.6.3.4) compare
Pf6N2E2_3351 -1.0 -3.9 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_2509 -1.0 -1.7 UDP-glucose 4-epimerase (EC 5.1.3.2) compare
Pf6N2E2_5841 -1.0 -1.1 GlcG protein compare
Pf6N2E2_2746 -1.0 -3.8 Outer membrane protein NlpB, lipoprotein component of the protein assembly complex (forms a complex with YaeT, YfiO, and YfgL); Lipoprotein-34 precursor compare
Pf6N2E2_5258 -1.0 -5.2 Sulfate adenylyltransferase subunit 1 (EC 2.7.7.4) / Adenylylsulfate kinase (EC 2.7.1.25) compare
Pf6N2E2_4982 -1.0 -3.4 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase (EC 6.3.2.-) compare
Pf6N2E2_5676 -1.0 -2.9 Aspartokinase (EC 2.7.2.4) compare
Pf6N2E2_4640 -1.0 -2.1 hypothetical protein compare
Pf6N2E2_5257 -1.0 -5.8 Sulfate adenylyltransferase subunit 2 (EC 2.7.7.4) compare
Pf6N2E2_4162 -1.0 -2.7 DNA polymerase I (EC 2.7.7.7) compare
Pf6N2E2_4147 -1.0 -6.5 Fused spore maturation proteins A and B compare
Pf6N2E2_3876 -1.0 -2.9 Agmatine deiminase (EC 3.5.3.12) compare
Pf6N2E2_1758 -1.0 -2.2 Transcriptional regulator, MarR family compare
Pf6N2E2_3786 -1.0 -4.8 Twin-arginine translocation protein TatC compare
Pf6N2E2_1085 -0.9 -2.9 Fe2+/Zn2+ uptake regulation proteins compare
Pf6N2E2_1044 -0.9 -2.1 hypothetical protein compare
Pf6N2E2_4352 -0.9 -1.4 ATP-dependent DNA helicase RecG (EC 3.6.1.-) compare
Pf6N2E2_5242 -0.9 -1.5 Malate:quinone oxidoreductase (EC 1.1.5.4) compare
Pf6N2E2_1534 -0.9 -2.1 Probable transmembrane protein compare
Pf6N2E2_309 -0.9 -1.1 FIG00957702: hypothetical protein compare
Pf6N2E2_3833 -0.9 -2.8 hypothetical protein compare
Pf6N2E2_51 -0.9 -4.0 hypothetical protein compare
Pf6N2E2_5338 -0.9 -7.4 Ubiquinol--cytochrome c reductase, cytochrome B subunit (EC 1.10.2.2) compare
Pf6N2E2_4562 -0.9 -2.1 L-cystine uptake protein TcyP compare
Pf6N2E2_5806 -0.9 -2.4 hypothetical protein compare
Pf6N2E2_3385 -0.9 -6.0 Predicted D-lactate dehydrogenase, Fe-S protein, FAD/FMN-containing compare
Pf6N2E2_2258 -0.9 -5.1 Transaldolase (EC 2.2.1.2) compare
Pf6N2E2_5339 -0.9 -5.7 ubiquinol cytochrome C oxidoreductase, cytochrome C1 subunit compare
Pf6N2E2_3656 -0.8 -6.0 Probable transcription regulator Mig-14 compare
Pf6N2E2_5188 -0.8 -2.2 Ribosomal-protein-S18p-alanine acetyltransferase (EC 2.3.1.-) compare
Pf6N2E2_5524 -0.8 -5.2 Outer membrane porin, OprD family compare
Pf6N2E2_799 -0.8 -2.8 hypothetical protein compare
Pf6N2E2_2440 -0.8 -1.2 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_4205 -0.8 -2.1 Chromosome (plasmid) partitioning protein ParA compare
Pf6N2E2_3885 -0.8 -1.5 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7) compare
Pf6N2E2_5950 -0.8 -2.4 Phosphate:acyl-ACP acyltransferase PlsX compare
Pf6N2E2_2640 -0.8 -1.4 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_2225 -0.8 -1.6 FIG00953489: hypothetical protein compare
Pf6N2E2_5739 -0.8 -0.8 Cobalamin biosynthesis protein BluB @ 5,6-dimethylbenzimidazole synthase, flavin destructase family compare
Pf6N2E2_3908 -0.8 -3.1 Glutamate--cysteine ligase (EC 6.3.2.2) compare
Pf6N2E2_2207 -0.8 -3.0 cytochrome b(561) compare
Pf6N2E2_4599 -0.8 -1.6 Integral membrane protein YggT, involved in response to extracytoplasmic stress (osmotic shock) compare
Pf6N2E2_5156 -0.8 -0.7 Two-component sensor CbrB: intrcellular carbon:nitrogen balance compare
Pf6N2E2_5705 -0.8 -1.6 Sensor protein PhoQ (EC 2.7.13.3) compare
Pf6N2E2_5153 -0.8 -3.6 3-methyl-2-oxobutanoate hydroxymethyltransferase (EC 2.1.2.11) compare
Pf6N2E2_2286 -0.8 -1.7 FIG00953287: hypothetical protein compare
Pf6N2E2_3261 -0.8 -4.8 hypothetical protein compare
Pf6N2E2_1932 -0.7 -2.1 Transcriptional regulator, IclR family compare
Pf6N2E2_4824 -0.7 -2.4 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85) compare
Pf6N2E2_5150 -0.7 -2.8 Glucose-6-phosphate isomerase (EC 5.3.1.9) compare
Pf6N2E2_638 -0.7 -2.2 4-carboxymuconolactone decarboxylase domain/alkylhydroperoxidase AhpD family core domain protein compare
Pf6N2E2_2068 -0.7 -3.2 5-methyltetrahydrofolate--homocysteine methyltransferase (EC 2.1.1.13) compare
Pf6N2E2_1987 -0.7 -1.0 hypothetical protein compare
Pf6N2E2_84 -0.7 -1.6 hypothetical protein compare
Pf6N2E2_4152 -0.7 -4.0 alginate biosynthesis transcriptional regulatory protein AlgB compare
Pf6N2E2_5574 -0.7 -3.0 Glycerol kinase (EC 2.7.1.30) compare
Pf6N2E2_2013 -0.7 -0.9 hypothetical protein compare
Pf6N2E2_1567 -0.7 -3.3 FIG00964846: hypothetical protein compare
Pf6N2E2_2018 -0.7 -1.3 hypothetical protein compare
Pf6N2E2_4153 -0.7 -1.7 Sensory box histidine kinase compare
Pf6N2E2_1806 -0.7 -2.0 hypothetical protein compare
Pf6N2E2_2707 -0.7 -2.7 Allophanate hydrolase 2 subunit 1 (EC 3.5.1.54) compare
Pf6N2E2_4585 -0.7 -4.8 Cell division protein FtsX compare
Pf6N2E2_2384 -0.7 -1.5 CmpX compare
Pf6N2E2_2156 -0.7 -1.7 Putative polyketide synthase (Fragment) compare
Pf6N2E2_2633 -0.7 -2.4 Nitroreductase family protein compare
Pf6N2E2_5337 -0.7 -4.2 Ubiquinol-cytochrome C reductase iron-sulfur subunit (EC 1.10.2.2) compare
Pf6N2E2_1089 -0.7 -1.2 Delta 1-piperideine-2-carboxylate reductase (EC 1.5.1.21) / Delta 1-pyrroline-2-carboxylate reductase (EC 1.5.1.1) compare
Pf6N2E2_1839 -0.7 -2.4 2-hydroxycyclohexanecarboxyl-CoA dehydrogenase (EC 1.1.1.-) compare
Pf6N2E2_3762 -0.7 -3.2 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_4204 -0.7 -0.7 rRNA small subunit 7-methylguanosine (m7G) methyltransferase GidB compare
Pf6N2E2_4454 -0.7 -2.8 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_4999 -0.7 -2.8 Membrane-bound lytic murein transglycosylase B precursor (EC 3.2.1.-) compare
Pf6N2E2_5001 -0.7 -0.4 D-alanyl-D-alanine carboxypeptidase (EC 3.4.16.4) compare
Pf6N2E2_4764 -0.7 -2.2 Dethiobiotin synthetase (EC 6.3.3.3) compare
Pf6N2E2_1596 -0.7 -1.3 Periplasmic nitrate reductase component NapD compare
Pf6N2E2_3840 -0.7 -1.8 FIG00956267: hypothetical protein compare
Pf6N2E2_4360 -0.7 -4.1 Bona fide RidA/YjgF/TdcF/RutC subgroup compare
Pf6N2E2_3373 -0.7 -1.4 Outer membrane lipoprotein SmpA, a component of the essential YaeT outer-membrane protein assembly complex compare


Specific Phenotypes

None in this experiment

For Pseudomonas fluorescens FW300-N2E2 in carbon source experiments