Experiment set11H7 for Pseudomonas stutzeri RCH2

Compare to:

LB with Cisplatin 0.003 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_3648 -5.4 -7.4 anthranilate phosphoribosyltransferase compare
Psest_2545 -5.3 -3.1 recombination protein RecR compare
Psest_3090 -5.1 -7.7 DNA repair protein RecO conserved
Psest_1492 -4.7 -7.2 DNA-binding ferritin-like protein (oxidative damage protectant) compare
Psest_3647 -4.6 -8.2 Indole-3-glycerol phosphate synthase compare
Psest_0004 -4.4 -13.5 recF protein conserved
Psest_1296 -4.3 -7.8 excinuclease ABC, B subunit conserved
Psest_2584 -4.3 -7.3 Phosphoribosylanthranilate isomerase compare
Psest_2259 -4.3 -15.1 excinuclease ABC, C subunit conserved
Psest_3576 -4.2 -21.6 excinuclease ABC, A subunit conserved
Psest_0063 -3.9 -12.7 tryptophan synthase, beta subunit compare
Psest_3650 -3.8 -15.2 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0062 -3.8 -11.1 tryptophan synthase, alpha subunit compare
Psest_4219 -3.7 -2.6 DNA polymerase I compare
Psest_4078 -3.7 -2.2 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_1653 -3.4 -18.5 transcription-repair coupling factor (mfd) conserved
Psest_0962 -3.2 -12.4 DNA repair protein RecN conserved
Psest_2872 -3.2 -1.9 protein RecA compare
Psest_1496 -3.0 -1.2 Holliday junction DNA helicase, RuvA subunit compare
Psest_3649 -2.8 -9.7 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0309 -2.8 -1.5 RND family efflux transporter, MFP subunit compare
Psest_4191 -2.8 -3.2 Transcriptional regulator compare
Psest_1544 -2.7 -7.4 single-stranded-DNA-specific exonuclease RecJ conserved
Psest_3960 -2.7 -1.9 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_0998 -2.6 -2.7 poly(A) polymerase compare
Psest_3767 -2.6 -5.0 tyrosine recombinase XerC compare
Psest_3401 -2.6 -8.3 DNA repair protein RadA conserved
Psest_2235 -2.6 -8.3 DNA damage response nuclease (from data) conserved
Psest_2304 -2.6 -1.4 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_0411 -2.5 -12.3 biotin synthetase compare
Psest_1869 -2.5 -10.0 ATP-dependent DNA helicase RecQ conserved
Psest_3031 -2.5 -0.8 hypothetical protein compare
Psest_2025 -2.5 -1.2 cold shock domain protein CspD compare
Psest_1660 -2.4 -2.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_2648 -2.4 -2.3 hypothetical protein compare
Psest_0259 -2.3 -1.0 cell division ATP-binding protein FtsE compare
Psest_0031 -2.3 -1.7 Uncharacterized conserved protein compare
Psest_0078 -2.2 -1.2 hypothetical protein compare
Psest_2236 -2.2 -12.2 Rad3-related DNA helicases conserved
Psest_1235 -2.1 -5.2 Leucyl aminopeptidase compare
Psest_3565 -2.1 -1.7 hypothetical protein compare
Psest_1532 -2.1 -4.7 DNA recombination-dependent growth factor C compare
Psest_0515 -2.0 -5.0 rare lipoprotein A compare
Psest_0737 -2.0 -1.0 Cu(I)-responsive transcriptional regulator compare
Psest_2946 -2.0 -2.0 septum site-determining protein MinD compare
Psest_0413 -2.0 -6.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_4098 -2.0 -4.5 Superfamily I DNA and RNA helicases compare
Psest_1525 -2.0 -5.0 Uncharacterized protein conserved in bacteria compare
Psest_4274 -2.0 -2.1 hypothetical protein compare
Psest_0161 -1.9 -2.9 Membrane-bound metallopeptidase compare
Psest_1999 -1.9 -1.1 pseudouridine synthase compare
Psest_0280 -1.9 -11.2 homoserine O-acetyltransferase compare
Psest_0401 -1.9 -2.3 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_3129 -1.8 -1.2 tyrosine recombinase XerD compare
Psest_3881 -1.8 -1.3 hypothetical protein compare
Psest_0310 -1.8 -3.5 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_0260 -1.8 -1.7 Cell division protein compare
Psest_0279 -1.8 -5.9 methionine biosynthesis protein MetW compare
Psest_2243 -1.7 -1.1 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_0805 -1.7 -2.4 hypothetical protein compare
Psest_2530 -1.7 -4.6 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_1663 -1.7 -3.2 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes compare
Psest_3377 -1.7 -1.0 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_3496 -1.7 -1.1 Predicted metal-binding protein compare
Psest_2532 -1.7 -2.9 Uncharacterized protein conserved in bacteria compare
Psest_2651 -1.7 -3.7 DNA topoisomerase I, bacterial compare
Psest_1617 -1.7 -2.2 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Psest_2066 -1.6 -1.2 ABC-type uncharacterized transport system, permease component compare
Psest_1920 -1.6 -0.8 Uncharacterized protein conserved in bacteria compare
Psest_0306 -1.6 -9.7 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_3458 -1.6 -2.6 hypothetical protein compare
Psest_0097 -1.6 -1.4 phosphonates metabolism transcriptional regulator PhnF compare
Psest_0514 -1.6 -4.4 lytic murein transglycosylase B compare
Psest_4142 -1.6 -1.4 hypothetical protein compare
Psest_1103 -1.6 -2.6 GTP-binding protein YchF compare
Psest_1543 -1.5 -4.5 Predicted transcription regulator, contains HTH domain (MarR family) compare
Psest_1979 -1.5 -3.5 Nucleotidyltransferase/DNA polymerase involved in DNA repair compare
Psest_2265 -1.5 -3.0 Outer membrane protein compare
Psest_0415 -1.5 -3.6 dethiobiotin synthase compare
Psest_0115 -1.5 -1.1 Predicted integral membrane protein compare
Psest_2229 -1.5 -2.4 Uncharacterized protein conserved in bacteria compare
Psest_3092 -1.5 -1.5 ribonuclease III, bacterial compare
Psest_1008 -1.5 -1.0 hypothetical protein compare
Psest_2531 -1.5 -8.8 cytochrome c oxidase accessory protein FixG compare
Psest_4335 -1.5 -1.8 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems compare
Psest_3922 -1.4 -3.5 Response regulator of citrate/malate metabolism compare
Psest_3543 -1.4 -2.4 hypothetical protein compare
Psest_1079 -1.4 -4.4 Isopropylmalate/homocitrate/citramalate synthases compare
Psest_2850 -1.4 -1.2 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_4183 -1.4 -2.2 PilZ domain. compare
Psest_1173 -1.4 -4.2 hypothetical protein compare
Psest_3878 -1.4 -2.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_1879 -1.3 -2.6 Trk-type K+ transport systems, membrane components compare
Psest_2857 -1.3 -6.5 Rad3-related DNA helicases conserved
Psest_0412 -1.3 -6.6 8-amino-7-oxononanoate synthase compare
Psest_0673 -1.3 -3.1 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase compare
Psest_2285 -1.3 -2.7 ATP-dependent protease La compare
Psest_1226 -1.3 -2.0 hypothetical protein compare
Psest_3339 -1.3 -4.6 Signal transduction histidine kinase compare
Psest_3766 -1.2 -2.0 Uncharacterized protein conserved in bacteria compare
Psest_2810 -1.2 -3.3 5'/3'-nucleotidase SurE compare
Psest_0678 -1.2 -3.2 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region compare
Psest_2232 -1.2 -6.7 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_1873 -1.2 -3.0 Predicted permease, DMT superfamily compare
Psest_3536 -1.2 -1.2 hypothetical protein compare
Psest_1227 -1.2 -1.5 Predicted SAM-dependent methyltransferase compare
Psest_1242 -1.2 -1.9 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_4151 -1.2 -2.1 Flagellar hook capping protein compare
Psest_1657 -1.2 -1.0 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_0852 -1.2 -3.0 glucose-6-phosphate 1-dehydrogenase compare
Psest_1026 -1.2 -3.3 Uncharacterized iron-regulated protein compare
Psest_1724 -1.2 -2.6 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_2578 -1.2 -6.2 O-succinylhomoserine sulfhydrylase compare
Psest_1750 -1.2 -1.9 Protein of unknown function (DUF2802). compare
Psest_0503 -1.1 -1.2 Acyl dehydratase compare
Psest_0172 -1.1 -4.1 Uncharacterized protein conserved in bacteria compare
Psest_0498 -1.1 -1.0 ribosome small subunit-dependent GTPase A compare
Psest_3180 -1.1 -5.5 Exonuclease I compare
Psest_0697 -1.1 -1.6 ribosomal protein L9 compare
Psest_0725 -1.1 -1.5 Negative regulator of beta-lactamase expression compare
Psest_0719 -1.1 -3.1 Uncharacterized protein conserved in bacteria compare
Psest_3070 -1.1 -1.8 3-oxoadipyl-CoA thiolase compare
Psest_1163 -1.1 -3.3 diguanylate cyclase (GGDEF) domain compare
Psest_3231 -1.1 -1.2 hypothetical protein compare
Psest_1323 -1.1 -4.0 Hydroxypyruvate isomerase compare
Psest_0867 -1.1 -1.1 hypothetical protein compare
Psest_0732 -1.1 -3.2 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_1111 -1.1 -2.0 Flp pilus assembly protein TadD, contains TPR repeats compare
Psest_3480 -1.1 -1.8 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_3790 -1.0 -5.3 Cytochrome c5 compare
Psest_2293 -1.0 -0.9 hypothetical protein compare
Psest_3792 -1.0 -2.4 Putative translation initiation inhibitor, yjgF family compare
Psest_3777 -1.0 -2.2 diguanylate cyclase (GGDEF) domain compare
Psest_1498 -1.0 -1.4 tol-pal system-associated acyl-CoA thioesterase compare
Psest_1452 -1.0 -6.1 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_2527 -1.0 -4.6 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_4158 -1.0 -1.3 Flagellar motor protein compare
Psest_0833 -1.0 -2.9 Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains compare
Psest_0028 -1.0 -3.0 Coproporphyrinogen III oxidase compare
Psest_3456 -1.0 -1.0 RNA polymerase sigma factor, sigma-70 family compare
Psest_3170 -1.0 -3.3 molybdenum cofactor biosynthesis protein MoaC compare
Psest_1540 -1.0 -0.8 biotin-dependent carboxylase uncharacterized domain compare
Psest_3024 -1.0 -3.0 cytochrome d oxidase, subunit II (cydB) compare
Psest_0414 -1.0 -2.7 biotin biosynthesis protein BioC compare
Psest_2083 -1.0 -2.9 Putative sterol carrier protein compare
Psest_4044 -1.0 -1.0 type I site-specific deoxyribonuclease, HsdR family compare
Psest_4391 -1.0 -5.8 ATPases involved in chromosome partitioning compare
Psest_4278 -1.0 -2.5 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component compare
Psest_4342 -1.0 -3.2 Putative GTPases (G3E family) compare
Psest_2357 -1.0 -1.3 Short-chain dehydrogenases of various substrate specificities compare
Psest_3575 -1.0 -3.9 Arabinose efflux permease compare
Psest_3784 -1.0 -1.8 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1595 -1.0 -0.9 Copper chaperone compare
Psest_3518 -1.0 -0.8 Transcriptional regulators compare
Psest_3014 -1.0 -1.3 cob(I)alamin adenosyltransferase compare
Psest_2565 -1.0 -1.8 Transcriptional regulator compare
Psest_2348 -1.0 -2.2 urea carboxylase-associated protein 2 compare
Psest_0385 -1.0 -1.6 Conserved secreted protein compare
Psest_0257 -0.9 -1.8 Predicted Zn-dependent peptidases compare
Psest_1870 -0.9 -0.7 Transcriptional regulators compare
Psest_2260 -0.9 -4.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_0489 -0.9 -1.6 phosphoserine phosphatase SerB compare
Psest_2775 -0.9 -2.1 Glycerol-3-phosphate dehydrogenase compare
Psest_1126 -0.9 -3.6 Uncharacterized protein conserved in bacteria compare
Psest_1029 -0.9 -2.1 Regulator of competence-specific genes compare
Psest_2434 -0.9 -2.4 Protein of unknown function (DUF2892). compare
Psest_0814 -0.9 -1.0 MoxR-like ATPases compare
Psest_0311 -0.9 -2.9 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_2646 -0.9 -1.5 SOS regulatory protein LexA compare
Psest_1986 -0.9 -0.8 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_3128 -0.9 -2.3 Protein-disulfide isomerase compare
Psest_3422 -0.9 -1.7 hypothetical protein compare
Psest_0114 -0.9 -1.5 RNA polymerase sigma factor, sigma-70 family compare
Psest_2543 -0.9 -2.4 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component compare
Psest_1218 -0.9 -2.3 Predicted endonuclease containing a URI domain compare
Psest_1463 -0.9 -0.6 SufE protein probably involved in Fe-S center assembly compare
Psest_4209 -0.9 -1.0 Uncharacterized conserved small protein compare
Psest_2953 -0.9 -1.2 Histone acetyltransferase compare
Psest_2766 -0.9 -0.7 hypothetical protein compare
Psest_2613 -0.9 -0.9 hypothetical protein compare
Psest_2101 -0.9 -0.8 hypothetical protein compare
Psest_0823 -0.9 -2.2 Transcriptional regulators compare
Psest_0292 -0.9 -1.5 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_1661 -0.9 -1.0 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_0487 -0.9 -1.9 Uncharacterized protein conserved in bacteria compare
Psest_3191 -0.9 -1.6 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases compare
Psest_3100 -0.9 -2.0 RNA polymerase sigma factor RpoE compare
Psest_3338 -0.8 -0.9 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_4258 -0.8 -2.1 ABC-type uncharacterized transport system, auxiliary component compare
Psest_1195 -0.8 -2.0 xanthine permease compare
Psest_1619 -0.8 -2.5 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 compare
Psest_4102 -0.8 -1.5 peroxiredoxin, Ohr subfamily compare
Psest_2122 -0.8 -0.8 Parvulin-like peptidyl-prolyl isomerase compare
Psest_1282 -0.8 -1.0 Amidases related to nicotinamidase compare
Psest_0652 -0.8 -2.2 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components compare
Psest_3816 -0.8 -0.7 DNA-directed RNA polymerase, omega subunit compare
Psest_3839 -0.8 -2.7 D-lactate/glycolate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_2911 -0.8 -0.8 Protein of unknown function (DUF2945). compare
Psest_0557 -0.8 -4.7 Urease (EC 3.5.1.5) (from data) compare
Psest_3151 -0.8 -1.3 hypothetical protein compare


Specific Phenotypes

For 14 genes in this experiment

For stress Cisplatin in Pseudomonas stutzeri RCH2

For stress Cisplatin across organisms