Experiment set11H43 for Pseudomonas stutzeri RCH2

Compare to:

LB with D-Cycloserine 0.032 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0062 -6.4 -6.3 tryptophan synthase, alpha subunit compare
Psest_3647 -5.8 -5.7 Indole-3-glycerol phosphate synthase compare
Psest_0063 -5.7 -5.6 tryptophan synthase, beta subunit compare
Psest_3648 -5.6 -5.4 anthranilate phosphoribosyltransferase compare
Psest_2011 -5.2 -8.0 Predicted permease compare
Psest_3510 -5.0 -12.0 Na+-dependent transporters of the SNF family compare
Psest_2584 -4.9 -4.4 Phosphoribosylanthranilate isomerase compare
Psest_1492 -4.5 -4.4 DNA-binding ferritin-like protein (oxidative damage protectant) compare
Psest_3650 -4.2 -13.9 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_1772 -4.1 -4.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0542 -4.1 -13.4 AMP nucleosidase compare
Psest_0359 -3.8 -3.4 Transcriptional regulators compare
Psest_0759 -3.7 -1.9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT). compare
Psest_1496 -3.7 -1.4 Holliday junction DNA helicase, RuvA subunit compare
Psest_2025 -3.7 -1.1 cold shock domain protein CspD compare
Psest_4088 -3.5 -4.5 Transcriptional regulators compare
Psest_4078 -3.4 -2.5 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_0498 -3.4 -1.3 ribosome small subunit-dependent GTPase A compare
Psest_3649 -3.3 -10.7 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3190 -3.3 -7.2 pyruvate kinase compare
Psest_1879 -3.0 -2.9 Trk-type K+ transport systems, membrane components compare
Psest_2682 -3.0 -4.6 fumarate hydratase, class II compare
Psest_4219 -2.9 -2.0 DNA polymerase I compare
Psest_0020 -2.7 -5.7 K+ transport systems, NAD-binding component compare
Psest_0969 -2.7 -2.0 transcription elongation factor GreA compare
Psest_1366 -2.6 -1.7 hypothetical protein compare
Psest_2945 -2.6 -1.2 septum site-determining protein MinC compare
Psest_0958 -2.5 -6.5 Oligoketide cyclase/lipid transport protein compare
Psest_0218 -2.4 -3.1 Acyl-CoA hydrolase compare
Psest_0310 -2.4 -4.0 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_2333 -2.4 -1.1 Protein of unknown function (DUF3359). compare
Psest_2590 -2.3 -1.0 3-isopropylmalate dehydratase, small subunit compare
Psest_0845 -2.3 -0.8 hypothetical protein compare
Psest_0028 -2.2 -5.0 Coproporphyrinogen III oxidase compare
Psest_4314 -2.2 -4.8 ABC-type metal ion transport system, ATPase component compare
Psest_1466 -2.2 -2.9 transcriptional regulator, Spx/MgsR family compare
Psest_1870 -2.2 -1.0 Transcriptional regulators compare
Psest_3732 -2.2 -7.2 polyphosphate kinase 1 compare
Psest_1226 -2.1 -3.9 hypothetical protein compare
Psest_2855 -2.1 -1.5 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_3578 -2.0 -11.5 Catalase compare
Psest_3721 -2.0 -5.0 Malic enzyme compare
Psest_3092 -2.0 -1.7 ribonuclease III, bacterial compare
Psest_3118 -2.0 -7.0 endonuclease III conserved
Psest_2711 -1.9 -2.6 PilZ domain. compare
Psest_0260 -1.9 -1.6 Cell division protein compare
Psest_0411 -1.9 -7.6 biotin synthetase compare
Psest_2872 -1.9 -1.0 protein RecA compare
Psest_0413 -1.9 -5.5 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_1463 -1.9 -0.9 SufE protein probably involved in Fe-S center assembly compare
Psest_2786 -1.9 -0.9 Domain of unknown function (DUF3597). compare
Psest_0306 -1.9 -10.6 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_2561 -1.9 -1.0 hypothetical protein compare
Psest_1103 -1.8 -3.1 GTP-binding protein YchF compare
Psest_1491 -1.8 -2.2 Cold shock proteins compare
Psest_4298 -1.8 -0.9 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_2589 -1.7 -7.6 3-isopropylmalate dehydrogenase compare
Psest_1804 -1.7 -1.2 Superfamily II DNA and RNA helicases compare
Psest_1905 -1.7 -2.5 Uncharacterized conserved protein, contains double-stranded beta-helix domain compare
Psest_2285 -1.7 -2.7 ATP-dependent protease La compare
Psest_3810 -1.7 -1.1 orotate phosphoribosyltransferase compare
Psest_4243 -1.6 -2.0 type VI secretion lipoprotein, VC_A0113 family compare
Psest_2636 -1.6 -7.1 tryptophan synthase, beta subunit compare
Psest_0082 -1.6 -2.9 Domain of unknown function (DUF892). compare
Psest_2645 -1.6 -6.0 Transcriptional regulator compare
Psest_2613 -1.6 -1.4 hypothetical protein compare
Psest_3069 -1.6 -1.5 3-oxoadipate enol-lactonase compare
Psest_1574 -1.6 -2.0 phenazine biosynthesis protein PhzF family compare
Psest_1480 -1.6 -1.9 arsenate reductase (glutaredoxin) compare
Psest_2104 -1.6 -1.5 IscR-regulated protein YhgI compare
Psest_3458 -1.6 -2.8 hypothetical protein compare
Psest_2946 -1.5 -1.8 septum site-determining protein MinD compare
Psest_4191 -1.5 -2.7 Transcriptional regulator compare
Psest_0086 -1.5 -2.7 hypothetical protein compare
Psest_3767 -1.5 -4.4 tyrosine recombinase XerC compare
Psest_0412 -1.5 -6.9 8-amino-7-oxononanoate synthase compare
Psest_0078 -1.5 -0.9 hypothetical protein compare
Psest_2101 -1.5 -1.6 hypothetical protein compare
Psest_2983 -1.5 -2.1 hypothetical protein compare
Psest_4315 -1.5 -1.8 ABC-type metal ion transport system, permease component compare
Psest_2566 -1.5 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_3185 -1.5 -1.6 MoxR-like ATPases compare
Psest_2581 -1.4 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_1470 -1.4 -5.7 succinyldiaminopimelate transaminase conserved
Psest_0415 -1.4 -2.9 dethiobiotin synthase compare
Psest_3351 -1.4 -4.7 peptide chain release factor 3 compare
Psest_4371 -1.4 -1.9 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_1631 -1.4 -1.5 Uncharacterized conserved small protein compare
Psest_2708 -1.4 -6.1 transaldolase compare
Psest_0678 -1.4 -3.2 yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region compare
Psest_2405 -1.4 -1.6 NAD-dependent protein deacetylases, SIR2 family compare
Psest_0209 -1.4 -1.3 membrane protein AbrB duplication compare
Psest_0378 -1.4 -2.3 Lactate dehydrogenase and related dehydrogenases compare
Psest_4051 -1.4 -2.3 molybdenum-pterin binding domain compare
Psest_0133 -1.4 -1.0 type VI secretion protein, VC_A0107 family compare
Psest_2766 -1.3 -0.8 hypothetical protein compare
Psest_2018 -1.3 -1.9 Uncharacterized conserved protein compare
Psest_4318 -1.3 -4.5 Predicted dioxygenase of extradiol dioxygenase family compare
Psest_2718 -1.3 -1.1 hypothetical protein compare
Psest_1327 -1.3 -6.0 Superfamily II DNA/RNA helicases, SNF2 family compare
Psest_2862 -1.3 -6.3 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_1065 -1.3 -1.8 hypothetical protein compare
Psest_2539 -1.3 -2.4 adenine phosphoribosyltransferase compare
Psest_0414 -1.3 -3.2 biotin biosynthesis protein BioC compare
Psest_2809 -1.3 -1.7 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_0298 -1.3 -3.4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_1471 -1.3 -4.6 Predicted membrane protein compare
Psest_2114 -1.2 -3.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_1486 -1.2 -2.9 hypothetical protein compare
Psest_1910 -1.2 -3.0 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase compare
Psest_4406 -1.2 -1.0 hypothetical protein compare
Psest_0442 -1.2 -1.4 ATPases of the AAA+ class compare
Psest_3178 -1.2 -2.1 formyltetrahydrofolate deformylase compare
Psest_4274 -1.2 -2.0 hypothetical protein compare
Psest_1940 -1.2 -2.6 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain compare
Psest_3042 -1.2 -0.7 Nitrate reductase cytochrome c-type subunit compare
Psest_3421 -1.2 -2.6 hypothetical protein compare
Psest_0697 -1.2 -1.8 ribosomal protein L9 compare
Psest_2322 -1.2 -2.2 Transcriptional regulators compare
Psest_1472 -1.2 -5.1 Protein of unknown function (DUF3108). compare
Psest_0181 -1.2 -3.7 glycine cleavage system T protein compare
Psest_3707 -1.1 -2.9 Transcriptional regulator compare
Psest_1999 -1.1 -0.7 pseudouridine synthase compare
Psest_2046 -1.1 -1.7 hypothetical protein compare
Psest_0115 -1.1 -0.9 Predicted integral membrane protein compare
Psest_0515 -1.1 -2.3 rare lipoprotein A compare
Psest_3013 -1.1 -2.0 cobyrinic acid a,c-diamide synthase compare
Psest_1183 -1.1 -1.7 hydroxyisourate hydrolase compare
Psest_4276 -1.1 -2.2 hypothetical protein compare
Psest_0093 -1.1 -2.9 Uncharacterized enzyme of phosphonate metabolism compare
Psest_2092 -1.1 -2.0 hypothetical protein compare
Psest_3890 -1.1 -1.0 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_3168 -1.1 -1.2 Molybdopterin converting factor, large subunit compare
Psest_3479 -1.1 -3.0 molybdenum cofactor synthesis domain compare
Psest_0962 -1.1 -4.8 DNA repair protein RecN compare
Psest_3502 -1.1 -1.3 flavoprotein, HI0933 family/uncharacterized flavoprotein, PP_4765 family compare
Psest_1139 -1.1 -2.8 PAS domain S-box compare
Psest_1516 -1.1 -1.3 Uncharacterized lipoprotein compare
Psest_3426 -1.1 -4.2 Uncharacterized protein conserved in bacteria compare
Psest_2090 -1.1 -1.7 Protein of unknown function (DUF2970). compare
Psest_2976 -1.1 -1.0 hypothetical protein compare
Psest_0212 -1.0 -1.5 exodeoxyribonuclease V, gamma subunit compare
Psest_1665 -1.0 -1.6 hypothetical protein compare
Psest_3172 -1.0 -2.9 cation diffusion facilitator family transporter compare
Psest_2988 -1.0 -2.8 aspartate kinase, monofunctional class compare
Psest_2134 -1.0 -5.6 amino acid carrier protein compare
Psest_4155 -1.0 -2.6 Flagellin and related hook-associated proteins compare
Psest_0719 -1.0 -2.6 Uncharacterized protein conserved in bacteria compare
Psest_2460 -1.0 -1.3 hypothetical protein compare
Psest_0922 -1.0 -2.1 alkylhydroperoxidase AhpD family core domain compare
Psest_3926 -1.0 -5.4 GTP-binding protein TypA/BipA compare
Psest_0568 -1.0 -2.3 pseudouridine synthase compare
Psest_1990 -1.0 -2.2 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs compare
Psest_0842 -1.0 -0.9 anaerobic ribonucleoside-triphosphate reductase activating protein compare
Psest_3554 -1.0 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_1873 -1.0 -2.6 Predicted permease, DMT superfamily compare
Psest_2017 -1.0 -1.5 Predicted acyltransferase compare
Psest_2967 -1.0 -1.9 flagellar basal-body rod protein FlgC compare
Psest_2478 -1.0 -3.9 Na+/serine symporter compare
Psest_2037 -1.0 -2.8 uroporphyrin-III C-methyltransferase compare
Psest_2648 -1.0 -1.2 hypothetical protein compare
Psest_2778 -1.0 -1.8 Parvulin-like peptidyl-prolyl isomerase compare
Psest_1663 -1.0 -1.8 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes compare
Psest_3478 -1.0 -0.7 Cytochrome B561 compare
Psest_1540 -1.0 -0.7 biotin-dependent carboxylase uncharacterized domain compare
Psest_4045 -1.0 -2.5 Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen compare
Psest_2407 -1.0 -1.7 nitrite reductase [NAD(P)H], small subunit compare
Psest_0640 -1.0 -2.8 Uncharacterized conserved protein compare
Psest_4183 -1.0 -1.6 PilZ domain. compare
Psest_1185 -0.9 -1.2 heavy metal response regulator compare
Psest_2773 -0.9 -4.2 glycerol kinase compare
Psest_3389 -0.9 -1.6 hypothetical protein compare
Psest_0851 -0.9 -5.0 Transcriptional regulators compare
Psest_3370 -0.9 -5.6 prepilin-type N-terminal cleavage/methylation domain compare
Psest_0655 -0.9 -1.2 Chemotaxis signal transduction protein compare
Psest_1206 -0.9 -1.9 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_1763 -0.9 -2.4 hypothetical protein compare
Psest_3904 -0.9 -1.1 hypothetical protein compare
Psest_4307 -0.9 -1.7 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_2123 -0.9 -1.2 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_3425 -0.9 -4.1 Sortase and related acyltransferases compare
Psest_3303 -0.9 -2.7 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1115 -0.9 -1.5 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_1509 -0.9 -3.5 quinolinate synthetase complex, A subunit compare
Psest_1691 -0.9 -1.3 aminodeoxychorismate lyase compare
Psest_1750 -0.9 -1.0 Protein of unknown function (DUF2802). compare
Psest_3048 -0.9 -1.8 hypothetical protein compare
Psest_2434 -0.9 -1.4 Protein of unknown function (DUF2892). compare
Psest_3962 -0.9 -0.6 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_0558 -0.9 -0.5 urease, beta subunit compare
Psest_1768 -0.9 -1.6 thiopurine S-methyltransferase, Se/Te detoxification family compare
Psest_0848 -0.9 -1.9 hypothetical protein compare
Psest_0575 -0.9 -0.6 HrpA-like helicases compare
Psest_1031 -0.9 -4.0 Uncharacterized protein conserved in bacteria compare
Psest_1860 -0.8 -1.8 Uncharacterized conserved protein compare
Psest_3088 -0.8 -2.1 Protein of unknown function (DUF2905). compare
Psest_1037 -0.8 -1.6 acetolactate synthase, small subunit compare
Psest_2894 -0.8 -1.3 addiction module antidote protein, HigA family compare
Psest_0187 -0.8 -2.2 Metal-dependent hydrolase compare
Psest_3718 -0.8 -3.4 Tfp pilus assembly protein PilN compare


Specific Phenotypes

For 11 genes in this experiment

For stress D-Cycloserine in Pseudomonas stutzeri RCH2

For stress D-Cycloserine across organisms