Experiment set11H39 for Pseudomonas stutzeri RCH2

Compare to:

LB with MreB Perturbing Compound A22 0.005 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_1492 -4.6 -5.5 DNA-binding ferritin-like protein (oxidative damage protectant) compare
Psest_3648 -4.6 -9.7 anthranilate phosphoribosyltransferase compare
Psest_3647 -3.8 -8.6 Indole-3-glycerol phosphate synthase compare
Psest_2584 -3.7 -6.3 Phosphoribosylanthranilate isomerase compare
Psest_0719 -3.5 -9.4 Uncharacterized protein conserved in bacteria compare
Psest_3650 -3.2 -13.4 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0062 -3.1 -8.1 tryptophan synthase, alpha subunit compare
Psest_4219 -2.9 -2.0 DNA polymerase I compare
Psest_0063 -2.9 -11.3 tryptophan synthase, beta subunit compare
Psest_2333 -2.8 -1.4 Protein of unknown function (DUF3359). compare
Psest_3496 -2.3 -1.5 Predicted metal-binding protein compare
Psest_3270 -2.3 -2.6 probable S-adenosylmethionine-dependent methyltransferase, YraL family compare
Psest_3338 -2.2 -1.7 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_2651 -2.1 -4.1 DNA topoisomerase I, bacterial compare
Psest_3092 -2.0 -1.9 ribonuclease III, bacterial compare
Psest_0515 -2.0 -4.9 rare lipoprotein A compare
Psest_0575 -2.0 -1.1 HrpA-like helicases compare
Psest_2025 -2.0 -1.2 cold shock domain protein CspD compare
Psest_2945 -2.0 -1.6 septum site-determining protein MinC compare
Psest_1167 -1.9 -1.3 hypothetical protein compare
Psest_4078 -1.9 -2.0 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D compare
Psest_1999 -1.9 -1.3 pseudouridine synthase compare
Psest_3048 -1.9 -3.1 hypothetical protein compare
Psest_0725 -1.8 -2.3 Negative regulator of beta-lactamase expression compare
Psest_2285 -1.7 -3.4 ATP-dependent protease La compare
Psest_0759 -1.7 -2.0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT). compare
Psest_2613 -1.7 -1.5 hypothetical protein compare
Psest_3047 -1.6 -1.1 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_1510 -1.6 -3.0 Putative Zn-dependent protease, contains TPR repeats compare
Psest_2976 -1.5 -1.6 hypothetical protein compare
Psest_2304 -1.5 -1.2 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_3230 -1.5 -5.1 Uncharacterized conserved protein compare
Psest_3810 -1.5 -1.4 orotate phosphoribosyltransferase compare
Psest_1242 -1.4 -2.1 tRNA-guanine transglycosylase, queuosine-34-forming compare
Psest_1366 -1.4 -1.6 hypothetical protein compare
Psest_0516 -1.4 -7.3 D-alanyl-D-alanine carboxypeptidase compare
Psest_3145 -1.4 -1.4 hypothetical protein compare
Psest_3013 -1.4 -3.0 cobyrinic acid a,c-diamide synthase compare
Psest_2646 -1.4 -1.6 SOS regulatory protein LexA compare
Psest_0191 -1.4 -0.8 PAS domain S-box compare
Psest_0310 -1.4 -3.0 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_0020 -1.4 -4.2 K+ transport systems, NAD-binding component compare
Psest_1012 -1.4 -3.1 Signal transduction histidine kinase compare
Psest_2946 -1.3 -2.4 septum site-determining protein MinD compare
Psest_1417 -1.3 -1.3 hypothetical protein compare
Psest_1540 -1.3 -1.5 biotin-dependent carboxylase uncharacterized domain compare
Psest_0309 -1.3 -1.1 RND family efflux transporter, MFP subunit compare
Psest_2643 -1.3 -1.8 Beta-glucosidase-related glycosidases compare
Psest_1920 -1.2 -0.9 Uncharacterized protein conserved in bacteria compare
Psest_3842 -1.2 -3.6 Transcriptional regulators compare
Psest_4128 -1.2 -1.5 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_1804 -1.2 -1.6 Superfamily II DNA and RNA helicases compare
Psest_0193 -1.2 -0.9 conserved hypothetical protein compare
Psest_2992 -1.2 -4.3 Uncharacterized conserved protein compare
Psest_0466 -1.2 -2.8 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1679 -1.2 -1.7 ribonuclease, Rne/Rng family compare
Psest_4191 -1.2 -2.6 Transcriptional regulator compare
Psest_0514 -1.2 -4.6 lytic murein transglycosylase B compare
Psest_2991 -1.2 -4.7 hypothetical protein compare
Psest_1700 -1.2 -2.7 Transcriptional regulator compare
Psest_0503 -1.2 -1.6 Acyl dehydratase compare
Psest_0078 -1.2 -0.9 hypothetical protein compare
Psest_1879 -1.1 -1.5 Trk-type K+ transport systems, membrane components compare
Psest_2757 -1.1 -1.0 hypothetical protein compare
Psest_0094 -1.1 -2.4 Uncharacterized enzyme of phosphonate metabolism compare
Psest_3100 -1.1 -3.4 RNA polymerase sigma factor RpoE compare
Psest_2114 -1.1 -5.0 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_0401 -1.1 -1.7 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_2101 -1.1 -1.5 hypothetical protein compare
Psest_2894 -1.1 -2.3 addiction module antidote protein, HigA family compare
Psest_3754 -1.1 -3.0 Uncharacterized protein involved in response to NO compare
Psest_2308 -1.1 -1.0 Predicted Fe-S protein compare
Psest_1601 -1.1 -1.7 Signal transduction histidine kinase compare
Psest_4310 -1.1 -1.4 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_3938 -1.0 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_3400 -1.0 -1.0 Copper resistance protein D. compare
Psest_2545 -1.0 -2.4 recombination protein RecR compare
Psest_3502 -1.0 -1.7 flavoprotein, HI0933 family/uncharacterized flavoprotein, PP_4765 family compare
Psest_3146 -1.0 -1.1 hypothetical protein compare
Psest_2104 -1.0 -1.5 IscR-regulated protein YhgI compare
Psest_1472 -1.0 -5.0 Protein of unknown function (DUF3108). compare
Psest_1293 -1.0 -1.3 VanZ like family. compare
Psest_2983 -1.0 -1.7 hypothetical protein compare
Psest_3080 -1.0 -1.7 AraC-type DNA-binding domain-containing proteins compare
Psest_4252 -1.0 -2.8 Uncharacterized protein conserved in bacteria compare
Psest_0998 -1.0 -2.1 poly(A) polymerase compare
Psest_2773 -1.0 -4.1 glycerol kinase compare
Psest_0814 -1.0 -1.8 MoxR-like ATPases compare
Psest_1910 -1.0 -2.2 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase compare
Psest_1149 -0.9 -1.9 Protein affecting phage T7 exclusion by the F plasmid compare
Psest_0334 -0.9 -1.6 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1905 -0.9 -2.2 Uncharacterized conserved protein, contains double-stranded beta-helix domain compare
Psest_1082 -0.9 -1.4 Enoyl-CoA hydratase/carnithine racemase compare
Psest_1506 -0.9 -3.2 queuosine biosynthesis protein QueC compare
Psest_1774 -0.9 -1.6 Glutathione peroxidase compare
Psest_4258 -0.9 -2.9 ABC-type uncharacterized transport system, auxiliary component compare
Psest_4390 -0.9 -2.6 hypothetical protein compare
Psest_2758 -0.9 -2.2 Predicted transcriptional regulators compare
Psest_3860 -0.9 -1.6 Predicted permeases compare
Psest_1282 -0.9 -1.2 Amidases related to nicotinamidase compare
Psest_0115 -0.9 -0.9 Predicted integral membrane protein compare
Psest_0789 -0.9 -3.1 hypothetical protein compare
Psest_1551 -0.9 -1.9 Integral membrane protein, interacts with FtsH compare
Psest_2232 -0.9 -6.3 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_1160 -0.9 -2.8 Uncharacterized conserved protein compare
Psest_2566 -0.9 -0.8 Uncharacterized protein conserved in bacteria compare
Psest_2066 -0.9 -1.3 ABC-type uncharacterized transport system, permease component compare
Psest_3458 -0.9 -2.3 hypothetical protein compare
Psest_2030 -0.9 -3.3 leucyl/phenylalanyl-tRNA--protein transferase compare
Psest_0118 -0.9 -3.4 Predicted membrane protein compare
Psest_2090 -0.9 -2.0 Protein of unknown function (DUF2970). compare
Psest_0050 -0.9 -2.9 Predicted acetyltransferase compare
Psest_0551 -0.8 -2.7 PEP phosphonomutase and related enzymes compare
Psest_3649 -0.8 -3.7 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_3962 -0.8 -0.9 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_0277 -0.8 -1.0 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_2726 -0.8 -1.3 Rhodanese-related sulfurtransferase compare
Psest_0442 -0.8 -1.5 ATPases of the AAA+ class compare
Psest_3937 -0.8 -1.2 ATP-dependent protease HslVU, ATPase subunit compare
Psest_1656 -0.8 -1.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_3296 -0.8 -0.8 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_2718 -0.8 -0.9 hypothetical protein compare
Psest_0172 -0.8 -3.2 Uncharacterized protein conserved in bacteria compare
Psest_1707 -0.8 -2.9 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Psest_2591 -0.8 -1.6 3-isopropylmalate dehydratase, large subunit compare
Psest_1724 -0.8 -2.2 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_3190 -0.8 -3.3 pyruvate kinase compare
Psest_0521 -0.8 -4.4 lytic murein transglycosylase compare
Psest_3816 -0.8 -0.8 DNA-directed RNA polymerase, omega subunit compare
Psest_4338 -0.8 -2.2 Fe2+-dicitrate sensor, membrane component compare
Psest_1117 -0.8 -2.2 Lipid A 3-O-deacylase (PagL). compare
Psest_1227 -0.8 -1.4 Predicted SAM-dependent methyltransferase compare
Psest_1505 -0.8 -1.0 Organic radical activating enzymes compare
Psest_4406 -0.8 -1.0 hypothetical protein compare
Psest_0113 -0.8 -1.3 Uncharacterized protein conserved in bacteria compare
Psest_0133 -0.8 -0.9 type VI secretion protein, VC_A0107 family compare
Psest_2096 -0.8 -1.5 Domain of unknown function (DUF1883). compare
Psest_0958 -0.8 -3.1 Oligoketide cyclase/lipid transport protein compare
Psest_4177 -0.8 -1.3 flagellar biosynthetic protein FliP compare
Psest_1574 -0.8 -1.8 phenazine biosynthesis protein PhzF family compare
Psest_1480 -0.8 -1.9 arsenate reductase (glutaredoxin) compare
Psest_2907 -0.7 -0.8 Protein of unknown function (DUF3618). compare
Psest_2253 -0.7 -1.8 small redox-active disulfide protein 2 compare
Psest_1056 -0.7 -1.3 2-isopropylmalate synthase, bacterial type compare
Psest_2457 -0.7 -2.2 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Psest_2465 -0.7 -2.4 hypothetical protein compare
Psest_2517 -0.7 -2.0 hypothetical protein compare
Psest_3735 -0.7 -1.1 uncharacterized domain 1 compare
Psest_2994 -0.7 -3.7 Uncharacterized protein conserved in bacteria compare
Psest_3535 -0.7 -1.6 hypothetical protein compare
Psest_0259 -0.7 -0.8 cell division ATP-binding protein FtsE compare
Psest_1389 -0.7 -2.6 hypothetical protein compare
Psest_1451 -0.7 -1.3 Uncharacterized ABC-type transport system, permease components compare
Psest_1271 -0.7 -2.4 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family compare
Psest_1661 -0.7 -0.9 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_0279 -0.7 -2.9 methionine biosynthesis protein MetW compare
Psest_1777 -0.7 -2.0 hypothetical protein compare
Psest_4044 -0.7 -1.3 type I site-specific deoxyribonuclease, HsdR family compare
Psest_3301 -0.7 -0.7 Predicted transcriptional regulator, BolA superfamily compare
Psest_1871 -0.7 -2.7 Predicted esterase of the alpha-beta hydrolase superfamily compare
Psest_2266 -0.6 -1.4 hypothetical protein compare
Psest_0568 -0.6 -1.3 pseudouridine synthase compare
Psest_0791 -0.6 -2.0 Acyl-CoA dehydrogenases compare
Psest_2967 -0.6 -1.9 flagellar basal-body rod protein FlgC compare
Psest_0778 -0.6 -1.8 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin compare
Psest_0409 -0.6 -1.7 Putative homoserine kinase type II (protein kinase fold) compare
Psest_4261 -0.6 -3.2 ABC-type multidrug transport system, permease component compare
Psest_0378 -0.6 -2.2 Lactate dehydrogenase and related dehydrogenases compare
Psest_2999 -0.6 -2.1 molybdenum ABC transporter, periplasmic molybdate-binding protein compare
Psest_1525 -0.6 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_4103 -0.6 -0.5 AraC-type DNA-binding domain-containing proteins compare
Psest_0857 -0.6 -0.8 Membrane transporters of cations and cationic drugs compare
Psest_3954 -0.6 -0.9 Small protein A (tmRNA-binding) compare
Psest_2121 -0.6 -2.8 Predicted ATPase compare
Psest_3761 -0.6 -1.2 Transcription elongation factor compare
Psest_1052 -0.6 -1.6 Uncharacterized protein involved in chromosome partitioning compare
Psest_4405 -0.6 -1.1 hypothetical protein compare
Psest_2277 -0.6 -1.4 coenzyme PQQ biosynthesis protein A compare
Psest_3022 -0.6 -2.0 Predicted membrane protein compare
Psest_3896 -0.6 -1.3 arsenite-activated ATPase ArsA compare
Psest_2083 -0.6 -1.9 Putative sterol carrier protein compare
Psest_1323 -0.6 -2.0 Hydroxypyruvate isomerase compare
Psest_3027 -0.6 -2.3 AZL_007950 family protein compare
Psest_0359 -0.6 -1.2 Transcriptional regulators compare
Psest_2997 -0.6 -3.7 Long-chain fatty acid transport protein compare
Psest_3904 -0.6 -1.0 hypothetical protein compare
Psest_1204 -0.6 -0.7 Transcriptional regulators compare
Psest_3742 -0.6 -1.5 hypothetical protein compare
Psest_1395 -0.6 -1.4 Short-chain alcohol dehydrogenase of unknown specificity compare
Psest_0724 -0.6 -1.6 Deoxyinosine 3'endonuclease (endonuclease V) compare
Psest_0774 -0.6 -3.0 cytosine permease (from data) compare
Psest_0120 -0.6 -2.3 hypothetical protein compare
Psest_4001 -0.6 -2.5 acetylornithine deacetylase (ArgE) compare
Psest_0890 -0.6 -2.8 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase compare
Psest_1600 -0.6 -1.1 hypothetical protein compare
Psest_3180 -0.6 -2.8 Exonuclease I compare
Psest_2531 -0.6 -3.9 cytochrome c oxidase accessory protein FixG compare
Psest_0400 -0.6 -1.9 Geranylgeranyl pyrophosphate synthase compare
Psest_4241 -0.6 -1.9 hypothetical protein compare
Psest_0186 -0.6 -1.7 Protein-disulfide isomerase compare


Specific Phenotypes

None in this experiment

For Pseudomonas stutzeri RCH2 in stress experiments

For stress MreB Perturbing Compound A22 across organisms