Experiment set10S99 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Lysine

200 most important genes:

  gene name fitness t score description  
MMP_RS04445 -7.5 -7.4 P-II family nitrogen regulator compare
MMP_RS03450 -7.4 -2.1 glycine synthesis protein GlyXS (from data) compare
MMP_RS04710 -7.2 -2.0 hypothetical protein compare
MMP_RS06895 -6.8 -1.9 selenocysteine-specific translation elongation factor compare
MMP_RS01325 -6.8 -2.2 dihydroneopterin aldolase family protein compare
MMP_RS02685 -6.5 -10.0 molybdate ABC transporter substrate-binding protein compare
MMP_RS06400 -6.4 -1.8 4Fe-4S binding protein compare
MMP_RS04460 -6.3 -16.1 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS04440 -6.2 -8.1 nitrogenase iron protein compare
MMP_RS07435 -6.2 -2.0 GMP synthase subunit A compare
MMP_RS08715 -6.1 -2.0 formylmethanofuran dehydrogenase subunit B compare
MMP_RS06625 -6.0 -2.7 DNA primase compare
MMP_RS05930 -6.0 -2.2 3-isopropylmalate dehydratase large subunit compare
MMP_RS03435 -6.0 -1.9 ketol-acid reductoisomerase compare
MMP_RS03960 -5.9 -1.4 hypothetical protein compare
MMP_RS04465 -5.8 -13.0 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS00555 -5.7 -6.1 MFS transporter compare
MMP_RS02670 -5.7 -10.4 ATP-binding cassette domain-containing protein compare
MMP_RS04455 -5.6 -15.6 nitrogenase subunit alpha compare
MMP_RS04470 -5.5 -13.2 nitrogenase compare
MMP_RS07185 -5.4 -12.6 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS08210 -5.4 -2.7 phosphatidylglycerophosphatase A compare
MMP_RS04450 -5.3 -9.5 P-II family nitrogen regulator compare
MMP_RS06730 -5.3 -1.7 phosphopantothenate/pantothenate synthetase compare
MMP_RS02355 -5.2 -3.5 30S ribosomal protein S27ae compare
MMP_RS02680 -5.1 -4.8 ABC transporter permease compare
MMP_RS07730 -5.1 -1.8 pyruvate synthase subunit beta compare
MMP_RS05500 -5.1 -7.0 2-isopropylmalate synthase compare
MMP_RS07525 -5.0 -6.7 4Fe-4S binding protein compare
MMP_RS07355 -5.0 -0.8 transcription factor S compare
MMP_RS08500 -4.9 -4.8 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS02010 -4.8 -7.0 PHP domain-containing protein compare
MMP_RS01800 -4.7 -4.8 TIGR00303 family protein compare
MMP_RS07345 -4.7 -7.0 glycine synthesis protein GlyXL (from data) compare
MMP_RS08860 -4.6 -5.2 MinD/ParA family protein compare
MMP_RS08165 -4.5 -2.8 phosphoglycerate dehydrogenase compare
MMP_RS00300 -4.5 -0.7 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS09020 -4.4 -1.7 hypothetical protein compare
MMP_RS06475 -4.4 -5.0 FAD-dependent oxidoreductase compare
MMP_RS06270 -4.4 -5.3 TIGR00300 family protein compare
MMP_RS01755 -4.4 -1.0 DUF2097 domain-containing protein compare
MMP_RS02675 -4.3 -3.5 hypothetical protein compare
MMP_RS01175 -4.3 -3.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS04585 -4.2 -10.0 AIR synthase related protein compare
MMP_RS07845 -4.2 -2.3 LL-diaminopimelate aminotransferase compare
MMP_RS00040 -4.1 -6.1 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS06020 -4.0 -5.0 archaeoflavoprotein AfpA compare
MMP_RS00455 -4.0 -6.0 orotate phosphoribosyltransferase-like protein compare
MMP_RS07390 -4.0 -3.3 cell division protein FtsZ compare
MMP_RS03025 -4.0 -4.4 molybdenum cofactor guanylyltransferase compare
MMP_RS07005 -3.9 -0.6 4Fe-4S binding protein compare
MMP_RS08300 -3.9 -1.1 metal-sulfur cluster assembly factor compare
MMP_RS00735 -3.9 -3.5 5 10-methenyltetrahydromethanopterin hydrogenase compare
MMP_RS07635 -3.9 -6.8 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03580 -3.9 -4.5 signal recognition particle-docking protein FtsY compare
MMP_RS06285 -3.9 -2.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS02900 -3.9 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS03315 -3.8 -1.5 ferrous iron transport protein A compare
MMP_RS04090 -3.8 -3.1 hypothetical protein compare
MMP_RS06630 -3.7 -0.8 UPF0058 family protein compare
MMP_RS07365 -3.7 -9.9 2-phosphoglycerate kinase compare
MMP_RS05345 -3.6 -8.6 hypothetical protein compare
MMP_RS08460 -3.6 -2.5 proteasome-activating nucleotidase compare
MMP_RS02730 -3.6 -10.1 ModD protein compare
MMP_RS03640 -3.6 -3.7 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06315 -3.6 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS04890 -3.5 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS06855 -3.5 -8.8 hypothetical protein compare
MMP_RS02145 -3.5 -7.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS01830 -3.3 -1.9 tRNA-Val compare
MMP_RS01500 -3.3 -2.5 CBS domain-containing protein compare
MMP_RS07955 -3.3 -5.0 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS00310 -3.3 -9.3 CBS domain-containing protein compare
MMP_RS01385 -3.3 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS02240 -3.2 -3.1 methanogenesis marker 7 protein compare
MMP_RS07445 -3.2 -4.2 helix-turn-helix domain-containing protein compare
MMP_RS08635 -3.2 -2.0 UbiA family prenyltransferase compare
MMP_RS02345 -3.2 -3.3 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01700 -3.2 -0.7 dihydroxy-acid dehydratase compare
MMP_RS03700 -3.2 -7.2 sodium:proton antiporter compare
MMP_RS01005 -3.2 -1.2 riboflavin synthase compare
MMP_RS06295 -3.1 -5.3 methanogenesis marker 14 protein compare
MMP_RS01220 -3.1 -8.4 hypothetical protein compare
MMP_RS00695 -3.0 -0.7 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS06230 -3.0 -2.4 helix-turn-helix domain-containing protein compare
MMP_RS01265 -3.0 -1.8 hypothetical protein compare
MMP_RS08790 -3.0 -1.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS00810 -3.0 -8.0 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS08645 -3.0 -6.0 UPF0179 family protein compare
MMP_RS06120 -3.0 -2.1 UPF0147 family protein compare
MMP_RS02800 -3.0 -7.4 nucleotidyltransferase domain-containing protein compare
MMP_RS01380 -2.9 -5.8 PHP domain-containing protein compare
MMP_RS01020 -2.9 -1.3 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01795 -2.9 -1.6 methanogenesis marker 6 protein compare
MMP_RS04870 -2.9 -5.0 TIGR02253 family HAD-type hydrolase compare
MMP_RS03110 -2.9 -6.2 glycosyltransferase family 2 protein compare
MMP_RS07695 -2.9 -6.4 DUF3236 domain-containing protein compare
MMP_RS04780 -2.8 -2.8 ribonuclease P compare
MMP_RS00320 -2.8 -1.7 class I SAM-dependent methyltransferase compare
MMP_RS07380 -2.8 -2.5 transcription elongation factor Spt5 compare
MMP_RS08440 -2.7 -2.7 cell division protein SepF compare
MMP_RS03445 -2.7 -1.1 methanogenesis marker 17 protein compare
MMP_RS00985 -2.7 -4.7 CDC48 family AAA ATPase compare
MMP_RS00725 -2.7 -8.2 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC compare
MMP_RS04955 -2.7 -6.6 DNA topoisomerase I compare
MMP_RS05265 -2.7 -2.4 2-isopropylmalate synthase compare
MMP_RS00750 -2.7 -2.0 fumarate hydratase compare
MMP_RS04850 -2.6 -14.7 UPF0254 family protein compare
MMP_RS06725 -2.6 -8.6 hypothetical protein compare
MMP_RS01085 -2.6 -2.1 hypothetical protein compare
MMP_RS01455 -2.6 -4.0 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS01880 -2.6 -5.9 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06885 -2.6 -2.5 50S ribosome-binding GTPase compare
MMP_RS08435 -2.6 -2.8 Era-like GTP-binding protein compare
MMP_RS08155 -2.6 -4.5 hypothetical protein compare
MMP_RS07605 -2.5 -2.9 diadenylate cyclase compare
MMP_RS00915 -2.5 -5.4 DUF116 domain-containing protein compare
MMP_RS01545 -2.5 -1.1 CBS domain-containing protein compare
MMP_RS01885 -2.5 -6.7 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS08720 -2.5 -1.6 4Fe-4S binding protein compare
MMP_RS01225 -2.5 -4.3 DUF5379 domain-containing protein compare
MMP_RS02245 -2.4 -3.5 hypothetical protein compare
MMP_RS01610 -2.4 -3.0 hypothetical protein compare
MMP_RS07535 -2.4 -6.5 4Fe-4S binding protein compare
MMP_RS04215 -2.4 -6.2 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS07075 -2.4 -3.9 phosphomannomutase/phosphoglucomutase compare
MMP_RS04900 -2.3 -14.5 hypothetical protein compare
MMP_RS07545 -2.3 -1.1 HTH domain-containing protein compare
MMP_RS03600 -2.3 -2.4 triose-phosphate isomerase compare
MMP_RS02875 -2.3 -10.1 chorismate pyruvate-lyase family protein compare
MMP_RS05430 -2.2 -3.8 TIGR00288 family NYN domain-containing protein compare
MMP_RS08705 -2.2 -5.9 sulfopyruvate decarboxylase subunit beta compare
MMP_RS08650 -2.2 -2.8 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01875 -2.2 -7.7 N-acetyltransferase compare
MMP_RS09055 -2.2 -0.9 CAP domain-containing protein compare
MMP_RS03090 -2.2 -6.8 cation:proton antiporter compare
MMP_RS06340 -2.1 -6.4 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07575 -2.1 -4.3 RNA ligase partner protein compare
MMP_RS05020 -2.1 -3.5 hypothetical protein compare
MMP_RS07090 -2.1 -6.5 tRNA (adenine-N1)-methyltransferase compare
MMP_RS05765 -2.1 -3.9 M42 family metallopeptidase compare
MMP_RS05535 -2.1 -4.3 hypothetical protein compare
MMP_RS07735 -2.0 -0.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08855 -2.0 -6.0 hypothetical protein compare
MMP_RS01725 -2.0 -3.5 class I SAM-dependent methyltransferase family protein compare
MMP_RS08350 -2.0 -1.0 hypothetical protein compare
MMP_RS06375 -2.0 -3.4 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS08660 -2.0 -6.3 DHH family phosphoesterase compare
MMP_RS04685 -2.0 -2.8 DUF126 domain-containing protein compare
MMP_RS06355 -2.0 -1.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS03205 -2.0 -1.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS00730 -2.0 -3.9 5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB compare
MMP_RS07700 -2.0 -8.6 DUF1188 domain-containing protein compare
MMP_RS06105 -1.9 -6.3 hydrogenase maturation peptidase HycI compare
MMP_RS06395 -1.9 -2.6 ThiF family adenylyltransferase compare
MMP_RS03035 -1.9 -2.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS08330 -1.9 -4.0 NADH-quinone oxidoreductase subunit H compare
MMP_RS06175 -1.9 -4.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS03390 -1.9 -5.2 malate dehydrogenase compare
MMP_RS03300 -1.9 -0.9 TOBE domain-containing protein compare
MMP_RS07685 -1.9 -6.3 TIGR01212 family radical SAM protein compare
MMP_RS00315 -1.9 -5.4 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS00685 -1.9 -2.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS02135 -1.9 -2.8 DUF5612 domain-containing protein compare
MMP_RS02340 -1.8 -2.0 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03485 -1.8 -4.5 TIGR00267 family protein compare
MMP_RS00305 -1.8 -1.2 phosphoribosyl-ATP diphosphatase compare
MMP_RS08570 -1.8 -7.8 coenzyme F420-0:L-glutamate ligase compare
MMP_RS01960 -1.8 -0.8 hypothetical protein compare
MMP_RS07710 -1.8 -4.6 cell division protein FtsZ compare
MMP_RS02165 -1.8 -5.8 tRNA-dihydrouridine synthase compare
MMP_RS05250 -1.8 -1.2 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06670 -1.8 -3.1 glucose-6-phosphate isomerase compare
MMP_RS01445 -1.8 -4.6 hypothetical protein compare
MMP_RS07200 -1.8 -4.2 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS08820 -1.7 -4.0 hypothetical protein compare
MMP_RS07530 -1.7 -7.3 4Fe-4S binding protein compare
MMP_RS06900 -1.7 -2.5 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS01720 -1.7 -1.6 replication factor C large subunit compare
MMP_RS00895 -1.7 -3.2 hypothetical protein compare
MMP_RS08195 -1.7 -6.7 hypothetical protein compare
MMP_RS00515 -1.7 -0.8 DUF655 domain-containing protein compare
MMP_RS07755 -1.7 -1.1 DUF555 domain-containing protein compare
MMP_RS05920 -1.7 -0.5 50S ribosomal protein L37e compare
MMP_RS05460 -1.6 -6.9 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS06350 -1.6 -3.5 HesA/MoeB/ThiF family protein compare
MMP_RS04500 -1.6 -8.2 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS05635 -1.6 -6.6 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS09025 -1.6 -1.0 hypothetical protein compare
MMP_RS08785 -1.6 -1.0 RNA-protein complex protein Nop10 compare
MMP_RS02175 -1.6 -0.8 DUF1611 domain-containing protein compare
MMP_RS05295 -1.6 -6.5 minichromosome maintenance protein MCM compare
MMP_RS05540 -1.6 -1.5 hypothetical protein compare
MMP_RS02780 -1.6 -4.3 hypothetical protein compare
MMP_RS03560 -1.5 -10.3 Na+/H+ antiporter NhaC family protein compare
MMP_RS02930 -1.5 -1.9 class I SAM-dependent methyltransferase compare
MMP_RS04720 -1.5 -2.0 DedA family protein compare
MMP_RS07820 -1.5 -3.2 UPF0104 family protein compare
MMP_RS01600 -1.5 -1.5 50S ribosomal protein L15e compare
MMP_RS00900 -1.5 -1.9 50S ribosomal protein L39e compare


Specific Phenotypes

For 1 genes in this experiment

For nitrogen source L-Lysine in Methanococcus maripaludis S2

For nitrogen source L-Lysine across organisms