Experiment set10S99 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Lysine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS02885 +1.9 10.4 molybdopterin biosynthesis protein compare
MMP_RS08320 +1.8 5.6 molybdopterin molybdotransferase MoeA compare
MMP_RS08310 +1.7 3.2 TMEM165/GDT1 family protein compare
MMP_RS02290 +1.6 7.8 MBL fold metallo-hydrolase compare
MMP_RS00325 +1.5 2.5 RNA-binding protein compare
MMP_RS06720 +1.4 4.3 response regulator transcription factor compare
MMP_RS02605 +1.3 1.1 MotA/TolQ/ExbB proton channel family protein compare
MMP_RS06715 +1.3 8.1 cache domain-containing protein compare
MMP_RS08930 +1.2 1.3 hypothetical protein compare
MMP_RS00295 +1.2 2.7 gamma carbonic anhydrase family protein compare
MMP_RS04885 +1.2 7.1 sulfite exporter TauE/SafE family protein compare
MMP_RS07890 +1.2 2.4 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS08725 +1.1 0.9 Ni/Fe hydrogenase subunit alpha compare
MMP_RS02390 +1.1 3.8 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS00675 +1.1 1.1 nitroreductase family protein compare
MMP_RS07765 +1.0 5.8 sodium:alanine symporter family protein compare
MMP_RS08275 +1.0 4.6 hypothetical protein compare
MMP_RS05975 +1.0 1.4 hypothetical protein compare
MMP_RS01675 +1.0 1.4 hypothetical protein compare
MMP_RS08430 +1.0 3.2 HAD family hydrolase compare
MMP_RS08600 +1.0 1.9 flagellar protein D compare
MMP_RS06870 +1.0 4.4 DedA family protein compare
MMP_RS00395 +1.0 1.3 MGMT family protein compare
MMP_RS02045 +0.9 1.4 tRNA-Met compare
MMP_RS00130 +0.9 1.0 nickel-responsive transcriptional regulator NikR compare
MMP_RS06540 +0.9 1.8 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS05695 +0.9 3.4 phospholipase D-like domain-containing protein compare
MMP_RS06905 +0.9 1.5 hypothetical protein compare
MMP_RS01200 +0.9 2.5 hypothetical protein compare
MMP_RS06745 +0.9 2.2 DUF2119 domain-containing protein compare
MMP_RS01055 +0.9 2.7 hypothetical protein compare
MMP_RS00855 +0.9 2.7 DUF367 family protein compare
MMP_RS00290 +0.9 3.5 hypothetical protein compare
MMP_RS07915 +0.9 2.8 DUF4870 domain-containing protein compare
MMP_RS00450 +0.8 1.0 4Fe-4S binding protein compare
MMP_RS08260 +0.8 2.4 DUF99 family protein compare
MMP_RS07800 +0.8 2.7 ATP-binding cassette domain-containing protein compare
MMP_RS06345 +0.8 4.1 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06910 +0.8 3.3 RlmF-related methyltransferase compare
MMP_RS08390 +0.8 2.9 DUF5400 domain-containing protein compare
MMP_RS00345 +0.8 1.9 DUF2666 domain-containing protein compare
MMP_RS00660 +0.8 4.2 alkaline phosphatase family protein compare
MMP_RS07095 +0.8 2.7 PspC domain-containing protein compare
MMP_RS07860 +0.8 0.7 hypothetical protein compare
MMP_RS00950 +0.7 2.9 site-2 protease family protein compare
MMP_RS06685 +0.7 3.8 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS08555 +0.7 1.5 hypothetical protein compare
MMP_RS00650 +0.7 2.6 ABC transporter ATP-binding protein compare
MMP_RS05355 +0.7 0.5 hypothetical protein compare
MMP_RS00655 +0.7 1.5 hypothetical protein compare
MMP_RS04050 +0.7 1.7 hypothetical protein compare
MMP_RS08160 +0.7 2.2 EamA family transporter compare
MMP_RS03840 +0.7 1.9 hypothetical protein compare
MMP_RS08445 +0.7 2.3 DUF2099 family protein compare
MMP_RS01785 +0.7 4.4 hypothetical protein compare
MMP_RS00155 +0.7 2.3 heavy metal-binding domain-containing protein compare
MMP_RS02495 +0.7 1.2 hypothetical protein compare
MMP_RS03220 +0.7 1.7 RNA 2' 3'-cyclic phosphodiesterase compare
MMP_RS00430 +0.7 1.2 hypothetical protein compare
MMP_RS08670 +0.7 2.8 metallophosphoesterase compare
MMP_RS06525 +0.7 0.8 YciI family protein compare
MMP_RS07125 +0.6 1.4 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS07805 +0.6 2.6 ABC transporter permease compare
MMP_RS04145 +0.6 1.0 hypothetical protein compare
MMP_RS08630 +0.6 3.3 archaellar assembly protein FlaJ compare
MMP_RS08265 +0.6 2.7 rubrerythrin compare
MMP_RS01550 +0.6 2.4 DUF1624 domain-containing protein compare
MMP_RS01415 +0.6 1.5 DUF2067 domain-containing protein compare
MMP_RS01160 +0.6 2.2 DMT family transporter compare
MMP_RS02740 +0.6 1.7 hypothetical protein compare
MMP_RS08075 +0.6 1.6 DUF749 domain-containing protein compare
MMP_RS08070 +0.6 2.4 DUF2096 domain-containing protein compare
MMP_RS08380 +0.6 2.7 phosphatase PAP2 family protein compare
MMP_RS01570 +0.6 0.8 hypothetical protein compare
MMP_RS06075 +0.6 3.0 class I SAM-dependent methyltransferase compare
MMP_RS00990 +0.6 1.0 hypothetical protein compare
MMP_RS02805 +0.6 0.7 HEPN domain-containing protein compare
MMP_RS04945 +0.6 3.0 hypothetical protein compare
MMP_RS01120 +0.6 2.3 permease compare
MMP_RS08285 +0.6 2.2 serine/threonine protein kinase compare
MMP_RS03800 +0.6 2.2 hypothetical protein compare
MMP_RS05085 +0.6 2.5 AAA family ATPase compare
MMP_RS03490 +0.6 0.9 DUF2115 domain-containing protein compare
MMP_RS08340 +0.6 1.5 4Fe-4S binding protein compare
MMP_RS07560 +0.6 1.3 prefoldin subunit alpha compare
MMP_RS07840 +0.6 1.3 ribonuclease III compare
MMP_RS02410 +0.6 1.0 ABC transporter substrate-binding protein compare
MMP_RS03575 +0.6 2.6 ECF transporter S component compare
MMP_RS00125 +0.6 0.7 DUF2798 domain-containing protein compare
MMP_RS08245 +0.6 2.4 DUF4013 domain-containing protein compare
MMP_RS08775 +0.6 1.4 methanogenesis marker 9 domain-containing protein compare
MMP_RS05830 +0.6 1.7 peptidyl-prolyl cis-trans isomerase compare
MMP_RS08770 +0.5 1.7 hypothetical protein compare
MMP_RS01630 +0.5 2.1 N-glycosylase/DNA lyase compare
MMP_RS03675 +0.5 3.2 RimK family alpha-L-glutamate ligase compare
MMP_RS08475 +0.5 2.3 ABC transporter permease compare
MMP_RS03150 +0.5 3.0 phosphoglycerate mutase compare
MMP_RS07725 +0.5 1.5 4Fe-4S dicluster domain-containing protein compare
MMP_RS00400 +0.5 1.6 tributyrin esterase compare
MMP_RS00705 +0.5 1.0 hypothetical protein compare
MMP_RS05155 +0.5 2.5 hypothetical protein compare
MMP_RS05780 +0.5 2.6 multidrug resistance efflux transporter family protein compare
MMP_RS04100 +0.5 1.6 hypothetical protein compare
MMP_RS00195 +0.5 4.1 DUF4013 domain-containing protein compare
MMP_RS00670 +0.5 1.7 TIM barrel protein compare
MMP_RS05090 +0.5 1.9 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS02300 +0.5 1.5 NAD(P)H-dependent oxidoreductase compare
MMP_RS08835 +0.5 2.7 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS04635 +0.5 2.1 GNAT family N-acetyltransferase compare
MMP_RS07960 +0.5 2.0 sugar phosphate isomerase/epimerase compare
MMP_RS01095 +0.5 1.5 iron ABC transporter permease compare
MMP_RS07645 +0.5 1.7 aldehyde dehydrogenase family protein compare
MMP_RS04190 +0.5 2.8 hypothetical protein compare
MMP_RS06760 +0.5 1.2 hypothetical protein compare
MMP_RS03890 +0.5 1.9 DUF2540 domain-containing protein compare
MMP_RS02550 +0.5 2.1 helix-turn-helix transcriptional regulator compare
MMP_RS01060 +0.5 3.3 calcium/sodium antiporter compare
MMP_RS04595 +0.5 1.8 hypothetical protein compare
MMP_RS03065 +0.5 1.2 AzlC family ABC transporter permease compare
MMP_RS08130 +0.5 1.9 IGHMBP2 family helicase compare
MMP_RS08325 +0.5 2.6 hypothetical protein compare
MMP_RS06860 +0.5 0.8 4Fe-4S binding protein compare
MMP_RS08205 +0.5 2.4 stage II sporulation protein M compare
MMP_RS03430 +0.5 2.5 bile acid:sodium symporter family protein compare
MMP_RS00545 +0.5 1.4 XRE family transcriptional regulator compare
MMP_RS00080 +0.5 0.9 RecB-family nuclease compare
MMP_RS05315 +0.5 0.8 hypothetical protein compare
MMP_RS02375 +0.5 2.1 hypothetical protein compare
MMP_RS08235 +0.5 1.8 hypothetical protein compare
MMP_RS06965 +0.5 1.7 TIGR04014 family B12-binding domain/radical SAM domain-containing protein compare
MMP_RS08485 +0.5 2.1 tungstate ABC transporter substrate-binding protein WtpA compare
MMP_RS04735 +0.5 1.3 tautomerase family protein compare
MMP_RS05795 +0.5 2.0 redox-regulated ATPase YchF compare
MMP_RS05490 +0.5 1.4 IMPACT family protein compare
MMP_RS08760 +0.5 1.1 hypothetical protein compare
MMP_RS07150 +0.5 1.1 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS03340 +0.5 0.4 ABC transporter ATP-binding protein compare
MMP_RS01640 +0.5 2.1 2-oxoacid:acceptor oxidoreductase subunit alpha compare
MMP_RS02365 +0.5 1.7 nitrogen fixation compare
MMP_RS01495 +0.5 1.8 TraB/GumN family protein compare
MMP_RS07155 +0.5 2.1 MFS transporter compare
MMP_RS02385 +0.4 1.3 ATP-binding protein compare
MMP_RS05110 +0.4 2.3 16S ribosomal RNA methyltransferase A compare
MMP_RS06440 +0.4 1.6 CBS domain-containing protein compare
MMP_RS01320 +0.4 1.4 hypothetical protein compare
MMP_RS09050 +0.4 1.0 CAP domain-containing protein compare
MMP_RS01985 +0.4 1.2 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS00975 +0.4 2.3 HD domain-containing protein compare
MMP_RS08085 +0.4 2.5 hypothetical protein compare
MMP_RS00800 +0.4 1.8 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS00960 +0.4 0.9 iron export ABC transporter permease subunit FetB compare
MMP_RS07835 +0.4 1.1 TldD/PmbA family protein compare
MMP_RS05070 +0.4 1.5 4Fe-4S dicluster domain-containing protein compare
MMP_RS03740 +0.4 1.2 indolepyruvate oxidoreductase subunit beta compare
MMP_RS04800 +0.4 1.5 chemotaxis protein CheW compare
MMP_RS02370 +0.4 0.9 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS00700 +0.4 1.2 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS01210 +0.4 1.6 sodium:solute symporter compare
MMP_RS04060 +0.4 1.4 hypothetical protein compare
MMP_RS06545 +0.4 0.9 ferredoxin family protein compare
MMP_RS06705 +0.4 1.0 formate/nitrite transporter family protein compare
MMP_RS01260 +0.4 1.4 HDIG domain-containing protein compare
MMP_RS05960 +0.4 2.8 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS04205 +0.4 1.8 carboxymuconolactone decarboxylase family protein compare
MMP_RS07650 +0.4 2.3 TldD/PmbA family protein compare
MMP_RS05470 +0.4 1.7 DUF523 and DUF1722 domain-containing protein compare
MMP_RS07985 +0.4 2.2 nitroreductase family protein compare
MMP_RS05720 +0.4 0.7 signal recognition particle subunit SRP19/SEC65 family protein compare
MMP_RS00085 +0.4 1.8 DNA cytosine methyltransferase compare
MMP_RS07145 +0.4 2.0 AmmeMemoRadiSam system protein B compare
MMP_RS09065 +0.4 2.2 hypothetical protein compare
MMP_RS04105 +0.4 1.8 MarR family transcriptional regulator compare
MMP_RS06305 +0.4 2.1 transporter substrate-binding domain-containing protein compare
MMP_RS08400 +0.4 0.9 MJ0307 family thioredoxin compare
MMP_RS04305 +0.4 0.9 hypothetical protein compare
MMP_RS06250 +0.4 1.8 hypothetical protein compare
MMP_RS01660 +0.4 1.1 hypothetical protein compare
MMP_RS01850 +0.4 1.8 phosphate ABC transporter substrate-binding protein compare
MMP_RS02170 +0.4 1.6 CBS domain-containing protein compare
MMP_RS06650 +0.4 1.6 glycoside hydrolase family 57 protein compare
MMP_RS06500 +0.4 2.1 ATP-binding protein compare
MMP_RS05365 +0.4 0.9 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH compare
MMP_RS06320 +0.4 1.4 hypothetical protein compare
MMP_RS08640 +0.4 1.6 TIM barrel protein compare
MMP_RS01430 +0.4 1.2 mechanosensitive ion channel family protein compare
MMP_RS00185 +0.4 2.3 potassium channel protein compare
MMP_RS08080 +0.4 1.6 YchF/TatD family DNA exonuclease compare
MMP_RS03465 +0.4 0.4 adenine phosphoribosyltransferase compare
MMP_RS08395 +0.4 1.4 DsrE family protein compare
MMP_RS06990 +0.4 1.1 CatB-related O-acetyltransferase compare
MMP_RS08345 +0.4 1.6 4Fe-4S binding protein compare
MMP_RS06325 +0.4 0.5 hypothetical protein compare
MMP_RS08410 +0.4 1.2 DUF169 domain-containing protein compare
MMP_RS00105 +0.4 1.9 hypothetical protein compare
MMP_RS01435 +0.4 1.1 DMT family transporter compare
MMP_RS07720 +0.4 1.8 4Fe-4S binding protein compare
MMP_RS00280 +0.4 1.5 DUF2118 domain-containing protein compare
MMP_RS06065 +0.4 2.5 iron ABC transporter substrate-binding protein compare
MMP_RS08890 +0.4 2.3 glycosyltransferase family 4 protein compare
MMP_RS00665 +0.4 1.0 hypothetical protein compare


Specific Phenotypes

For 1 genes in this experiment

For nitrogen source L-Lysine in Methanococcus maripaludis S2

For nitrogen source L-Lysine across organisms